Basic Information

Insect: Drosophila takahashii
Gene Symbol: -
Assembly: GCA_018152695.1
Location: JAECXN010000003.1:8981470-8984066[-]

Transcription Factor Domain

TF Family: THAP
Domain: THAP domain
PFAM: PF05485
TF Group: Zinc-Coordinating Group
Description: The THAP domain is a putative DNA-binding domain (DBD) and probably also binds a zinc ion. It features the conserved C2CH architecture (consensus sequence: Cys - 2-4 residues - Cys - 35-50 residues - Cys - 2 residues - His). Other universal features include the location of the domain at the N-termini of proteins, its size of about 90 residues, a C-terminal AVPTIF box and several other conserved residues. Orthologues of the human THAP domain have been identified in other vertebrates and probably worms and flies, but not in other eukaryotes or any prokaryotes [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 1.5e-14 1.8e-11 44.4 0.4 1 86 70 139 70 140 0.84

2 7 2.7e-08 3.2e-05 24.4 0.6 1 62 167 223 167 238 0.79

3 7 6.1e-12 7.2e-09 36.1 0.0 1 87 243 314 243 314 0.80

4 7 1.4e-13 1.6e-10 41.4 0.0 1 86 337 411 337 412 0.82

5 7 7.6e-08 9e-05 22.9 0.4 1 58 445 496 445 523 0.80

6 7 4e-11 4.7e-08 33.5 0.5 1 87 534 604 534 604 0.78

7 7 1.1e-14 1.3e-11 44.9 2.8 1 85 667 738 667 740 0.80

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	1.5e-14	1.8e-11	44.4	0.4	1	86	70	139	70	140	0.84
2	7	2.7e-08	3.2e-05	24.4	0.6	1	62	167	223	167	238	0.79
3	7	6.1e-12	7.2e-09	36.1	0.0	1	87	243	314	243	314	0.80
4	7	1.4e-13	1.6e-10	41.4	0.0	1	86	337	411	337	412	0.82
5	7	7.6e-08	9e-05	22.9	0.4	1	58	445	496	445	523	0.80
6	7	4e-11	4.7e-08	33.5	0.5	1	87	534	604	534	604	0.78
7	7	1.1e-14	1.3e-11	44.9	2.8	1	85	667	738	667	740	0.80

Sequence Information

Coding Sequence: ATGGATGAAGTTCAGGTGAAGCAGGAGCTGGAGTCAGACGACGACTACGACTGTCAAATGGTGGAGGAGATCAAAATTAAGGCGGAACCACTAATGGAGGAGGAACTCCCGCCGGACGAGGACTTTCCGATGGAGGAGATGTATGTTAAAGTGGAGCCCTCCATGCTGGATAAAGTTAAGGAAGATCCGGAGATCAGGACACCGAAATGTTGCATTCCCACCTGTGGTCAGCAGGAAAGCGAACAAATTCGACTCTTTCGCTTTCCCAGCCAGGAAAATATGCTCATCCAGTGGCTAGTGAACACCGATATGAAGCCTCGCCTGGCTAATCCCCTAGAGCTTTTCGTGTGTCAGTTTCACTTTGAACCCGAAGCCTTTAAGCGGAATGAGCTCTTCGATTGGGCGGTGCCCACTTTATTACTCGGCCATGCAGGATTCGTGATTCCACTTTCGAAACAACCCTCTAAGGAAGTGATGAAGCACATCCGCAGGGAGTACTGCTCCGTGCTCAGTTGCTTCCGGGCCAAGGACGAAGGATACCGGCTGTATGAGTACCCAAAGGACGAGGCCAGCCGTCGCAGGTGGTCACGACGGTGCAGTCATAATCCTGTCCTGGTTGCCAGGCAAGGATTTCGCTTGTGCCGTTCGCACTTCGCCACGGACTCTTTTGATCCGGAGACTTGCGACTTGTTTGCGGGATCCTTGCCCTCCAGGGAGCTATTCACTTGCCTTGTGCCTGGCTGTGCGCAGGATGCAGCTGCTCCTGTGGGCTACTACAAAGTTCCTGTAACTAGCACTCTACTAAATGCCTGGAGCAACAACCTATTGATTGACCAACGAGATCTCCATCGTGATGACCTCCGCGTTTGCGGCCGTCACTTCGAGGACTACTGCTTCACGAATGACAACAAACTTCGTCCTGGTTCGCTGCCCACTCTCTTCCTGAATCATGGCCAGGAAATCCAGCCAAATCCGGGAAGTATAAAATTAGAGTTTCAAAAGATCGCTTGCATAGTGCCCGGCTGTGGACGCATCCGGCAGCCTGGAGAGAAACCGTTTTCCCCGTTTCCCAGACTGCCAGTTCTGGTCAAGAAGTGGCTACACAACTTTCGACTGGACGCCACCTGCGATGCGGTGGAAGGAATGATGGTCTGCGATGAGCACTTCGAGGAGTCCTGTTTAAAAAAGAGTTCAGGACCAAATCGAGTGCGTTTGGGAGCCATGCCGACCTTGAAACTGGGTCATTCCCATCGTGATCTCTACCTGACCAATATGAATCTTCTGGGGAAATCATCATGGGCTTTTTGGAGAATTGGAACAACCAGATTGGATTGCTGCTATCCGAACTGCGTAGAGCAGCATAAAATCAATTGCTACAATCTGCCAAAGATGGATAGTCTTCGCAAAGCGTGGCTGAACCACATGAACATTGAACTGCCTCCGGCCGACTCATCCTCGGATGAACCACAGCTCTGCCCGCTGCACTTCATCCTTCTGTACGAGCACAGTGCCGAAAACTTTGCCGATCACTCGTCCGACGCCTCTCTGGACGATAGCTACAAGGATGCCCGAAGCAAGAAACGAATGCAGGTCCTCAGGTGTGCCATCAAGGGATGCAATACCTTCCTGCCCAGAGACGGAGGCATCCTGCATTGTATGAAGACCATCAAGGAAATCGAGCAGATGTGGGTGGAAAACGGGCAGATGGAGTTGAATGAGAAGAAAGAATACAATCGGGTGTGTAGCAAGCACTTTGAACCGCAATGCTTCCAGGGTCAACGACTCCTCGAGTGGAGTGTGCCCACCCTGCACCTTCCAGGCGAGGCAGTGCATCAAAATGTCACCAGGGAGCAGTACAAGATTTACAACGAGGCGGCGAAGCTGAATGATTGGGAAGACGAGGAGGATGTTGATTACTCCGATTTAAATCCCCTTGCTGGGAAATCCATAGATGAGCCCAAGGATCAAGGACAGCGGAAGAAGTACAGTACCAATCGCTGCGCTGTTCCGCGTTGTAATAAGACTTTCAAGGACGTAACCCGAACTTTCCGCCTGCACAAGCTCCCCGATTCCGAGGAAGCAGCCAAAAAGTGGCTACACAACACCCAGGTGCAGATGGCCAGGGAGTACTGGCCCAGCTTTCGCATCTGCAGCCGCCACTTCGACGAGGATTGCTTCCAAGGATCGAGGGTGCGGAAGGGAGCCATGCCCACGCGTCGCATGGCAAGTGTCCTGCTGGGATCGATGTACGAAAGTGTGTGGAAAGCCAAGAAACGCAAACGTTCCTCCCGTTTTCAAAGGACTAAAAAGAAATAA
Protein Sequence: MDEVQVKQELESDDDYDCQMVEEIKIKAEPLMEEELPPDEDFPMEEMYVKVEPSMLDKVKEDPEIRTPKCCIPTCGQQESEQIRLFRFPSQENMLIQWLVNTDMKPRLANPLELFVCQFHFEPEAFKRNELFDWAVPTLLLGHAGFVIPLSKQPSKEVMKHIRREYCSVLSCFRAKDEGYRLYEYPKDEASRRRWSRRCSHNPVLVARQGFRLCRSHFATDSFDPETCDLFAGSLPSRELFTCLVPGCAQDAAAPVGYYKVPVTSTLLNAWSNNLLIDQRDLHRDDLRVCGRHFEDYCFTNDNKLRPGSLPTLFLNHGQEIQPNPGSIKLEFQKIACIVPGCGRIRQPGEKPFSPFPRLPVLVKKWLHNFRLDATCDAVEGMMVCDEHFEESCLKKSSGPNRVRLGAMPTLKLGHSHRDLYLTNMNLLGKSSWAFWRIGTTRLDCCYPNCVEQHKINCYNLPKMDSLRKAWLNHMNIELPPADSSSDEPQLCPLHFILLYEHSAENFADHSSDASLDDSYKDARSKKRMQVLRCAIKGCNTFLPRDGGILHCMKTIKEIEQMWVENGQMELNEKKEYNRVCSKHFEPQCFQGQRLLEWSVPTLHLPGEAVHQNVTREQYKIYNEAAKLNDWEDEEDVDYSDLNPLAGKSIDEPKDQGQRKKYSTNRCAVPRCNKTFKDVTRTFRLHKLPDSEEAAKKWLHNTQVQMAREYWPSFRICSRHFDEDCFQGSRVRKGAMPTRRMASVLLGSMYESVWKAKKRKRSSRFQRTKKK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00578574;
90% Identity: -
80% Identity: -