Basic Information

Insect: Drosophila suzukii
Gene Symbol: topi
Assembly: GCA_013340165.1
Location: WWNF01000006.1:5749824-5753538[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 5.7 3.9e+02 1.7 0.5 2 20 138 155 137 157 0.86

2 11 4.8e-06 0.00032 20.8 1.1 2 23 235 256 235 256 0.97

3 11 0.043 2.9 8.4 0.0 2 23 282 303 281 303 0.79

4 11 0.054 3.7 8.1 0.0 2 23 367 388 366 388 0.94

5 11 0.0016 0.11 12.8 0.5 1 22 435 456 435 459 0.90

6 11 9.5 6.4e+02 1.0 0.2 2 20 474 492 473 496 0.84

7 11 4.1e-07 2.8e-05 24.2 1.9 1 23 517 539 517 539 0.95

8 11 0.00094 0.064 13.6 1.3 1 23 545 570 545 570 0.96

9 11 0.46 31 5.2 0.5 1 23 576 598 576 598 0.86

10 11 3e-08 2.1e-06 27.7 0.4 1 23 604 626 604 626 0.99

11 11 0.0014 0.094 13.1 2.0 1 23 632 655 632 655 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	5.7	3.9e+02	1.7	0.5	2	20	138	155	137	157	0.86
2	11	4.8e-06	0.00032	20.8	1.1	2	23	235	256	235	256	0.97
3	11	0.043	2.9	8.4	0.0	2	23	282	303	281	303	0.79
4	11	0.054	3.7	8.1	0.0	2	23	367	388	366	388	0.94
5	11	0.0016	0.11	12.8	0.5	1	22	435	456	435	459	0.90
6	11	9.5	6.4e+02	1.0	0.2	2	20	474	492	473	496	0.84
7	11	4.1e-07	2.8e-05	24.2	1.9	1	23	517	539	517	539	0.95
8	11	0.00094	0.064	13.6	1.3	1	23	545	570	545	570	0.96
9	11	0.46	31	5.2	0.5	1	23	576	598	576	598	0.86
10	11	3e-08	2.1e-06	27.7	0.4	1	23	604	626	604	626	0.99
11	11	0.0014	0.094	13.1	2.0	1	23	632	655	632	655	0.96

Sequence Information

Coding Sequence: ATGAAGATTAACATCACGGGTGAATATACGCTAGCGGAGATCGAGGTGGAAGTGGACACCGAGTTGAGCGCCGAGGACCTGCAGCCCGGAGCCACCGTGCTGGCATCTAACGAGGGTGATGGCGGCCTGGAGCAGATAGTCAGCCACGAAGATCTGTCCAGGTTCTTTACCGTGGCGCCGGCGAGTGCCCTCCCCATGCCTACGGATGTTGTGGTGGAGCGCACCCTGGCGGATCCAGCCCTCAAGCAAATCCTGCAGGAGGCTGACGGCAAGAGAGGCTTCGATCCCAAGGCGGAGCAGTTGAAGATTCGCGAATTTCTGGCTGGGGTTACCAACAGCAAGATGACCACTGAGCAATCGGTGTTCCAAGGATCCCGTTCCAATTCCTCTGCGGCTGCTAGCAGCCGTATAAAGTGTCCCCAGTGTCAGGTCTACTATGATGCTGTTTCCTTCCAGAGCCACACCTGTGAAACCGAAGTCGATCGGAAACCTGCTGTAACAGTCACAGTTGCTCAGCAGGAGAAGCCCCCTGCTGTCCCCACTGTAAGTGCTCCTCCCGCTCCGCCCAGTAAGCCAGGCAGCAAGCGTGTGATCCTGGAGAACCAGGTGCGCCTGCGGCGCTACATGAAGGATGAGATGAAATACGACCTGGCCACCGGCGTTGATAGCTCGCGCGGCAGGAAGTCGGGGAAGGGTCCGAACGAGTGCACCATGTGCGACCGGAAGTTTGTGCATCCCTCTGGATTGGTGCGCCATATGGAGAAGCACGCTTTGGACATGATCCCTTCTCAGGCCAGCTTGCAGCCATATACAGCTCCGGCTGCCGGTTTCCATGTCGTGGTGAAGTGCAACATCTGTGGGCGCATCTTCTATGATCCGCTGGCGGCCTTGGAGCACGGCTCCATTCACTATCCGGAGCATGAAGAGCTGTGTCATATTCCGGAGGACCTGTATTCCTCTGGCAAAAAGGATTTCAAGGAACTTCTGCTGGAGGGTGAGATGCTGCTGGCCGGAGAGCTGACAGTAACGGTGGCCCAGCAAAAGGCTGGCCGTCGGGAGAGGGAGCTGTTCTCCAGCCTGATCCTGGGCAGCGTTTTGCAGTGCGAATTCTGCGAGTATATCTTCGCTGATATAGCCGAACTGCTCGTCCATTCGGCCTCCCATGTGGCGGAGCGGCGCTTCGAGTGTACCGCCTGCAACATGCAGATGAACACTGCGAAGGAGGCCAGCACCCACTTCCAGACGGACTGCATCTTTATGCGGGAGGCCATACGATCCCTGAGTGTCACCCTAAGTCGCCACTTTGTGTGCAATGTGTGCGAACTTAAGTTCGCCAACACAGATCTGCTCCAGGAGCATCGATACACCTCGTACCACTACTTCCCCCGGCTCAGCCAGAATGGTAagaagctgctgctgccttgCGAATTCTGCGAGGTCAACTTCGAGTTCGCTCACGAAATCCTGGCCCACAACGAGGAGAAGCACCTGAACAAGAAGAAGCGCGAAAAGGAAACGCGCAATGCGGGCACTGGTCGCTTGCGTCAGTATCTGTGCGACATCTGTGGCAAGTCGTACACCCAGTCGAGCCATCTGTGGCAGCACCTGCGCTTCCACCAAGGTGTCAAGCCGTTTGTCTGCCAGGAAGAGAACTGTGACCGGAAGTTCACCATTCGACCGGATCTGAACGACCACATCCGCAAGTGCCACACGGGCGAGCGTCCGTATCTCTGCCTGGTGTGTGGAAAGCGCTTCCTCACAGGATCCGTCTTCTACCAGCACCGTCTAATCCATCGCGGCGAGCGGCGCTACGAGTGTGAGGAGTGCGGCAAGCGCTTCTACCGGGCGGACGCCCTCAAGAACCACCAGCGCATCCACACCGGCGAAAAGCCTTATAGCTGTCTCTTCTGCACCAAGACCTTTCGCCAGCGTGGCGATCGGGACAAGCACATCCGGGCGCGTCACTCCCACTTGGACGCCAACTCGCGACTGATGATGCAGATGCAAAAGTTCCAGCTGGAGACGGCTGCTGCCCAGCGGGTGCAACATCATACCCCGGAGAagcaggcagcagcagcagcagcagcagcagcagctcttGGTGGCAGTCCTTCGGATGTAGCCTCTTGCTCGGGATCCGGATCTGCCGAGGCTGGCGACCAGGTGATACAGTATTCTGTTATTCAAGAGCCGCAAGAGGAATGA
Protein Sequence: MKINITGEYTLAEIEVEVDTELSAEDLQPGATVLASNEGDGGLEQIVSHEDLSRFFTVAPASALPMPTDVVVERTLADPALKQILQEADGKRGFDPKAEQLKIREFLAGVTNSKMTTEQSVFQGSRSNSSAAASSRIKCPQCQVYYDAVSFQSHTCETEVDRKPAVTVTVAQQEKPPAVPTVSAPPAPPSKPGSKRVILENQVRLRRYMKDEMKYDLATGVDSSRGRKSGKGPNECTMCDRKFVHPSGLVRHMEKHALDMIPSQASLQPYTAPAAGFHVVVKCNICGRIFYDPLAALEHGSIHYPEHEELCHIPEDLYSSGKKDFKELLLEGEMLLAGELTVTVAQQKAGRRERELFSSLILGSVLQCEFCEYIFADIAELLVHSASHVAERRFECTACNMQMNTAKEASTHFQTDCIFMREAIRSLSVTLSRHFVCNVCELKFANTDLLQEHRYTSYHYFPRLSQNGKKLLLPCEFCEVNFEFAHEILAHNEEKHLNKKKREKETRNAGTGRLRQYLCDICGKSYTQSSHLWQHLRFHQGVKPFVCQEENCDRKFTIRPDLNDHIRKCHTGERPYLCLVCGKRFLTGSVFYQHRLIHRGERRYECEECGKRFYRADALKNHQRIHTGEKPYSCLFCTKTFRQRGDRDKHIRARHSHLDANSRLMMQMQKFQLETAAAQRVQHHTPEKQAAAAAAAAAALGGSPSDVASCSGSGSAEAGDQVIQYSVIQEPQEE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00605785;
90% Identity: iTF_00602813;
80% Identity: -