Basic Information

Gene Symbol
-
Assembly
GCA_013340165.1
Location
WWNF01000001.1:20062098-20069482[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 14 0.00033 0.022 15.1 4.8 1 23 237 259 237 259 0.98
2 14 2.3e-05 0.0016 18.7 0.2 1 23 324 346 324 346 0.99
3 14 7.3e-08 5e-06 26.5 0.4 1 23 352 374 352 374 0.99
4 14 5.7e-06 0.00039 20.6 2.4 1 23 380 402 380 402 0.97
5 14 8.1e-06 0.00055 20.1 4.6 1 23 408 430 408 430 0.98
6 14 8e-06 0.00054 20.1 1.3 1 23 436 458 436 458 0.99
7 14 2.4e-06 0.00016 21.8 0.5 1 23 478 500 478 500 0.99
8 14 8e-07 5.4e-05 23.3 3.5 1 23 506 528 506 528 0.98
9 14 0.00025 0.017 15.4 5.6 1 23 534 556 534 556 0.98
10 14 2e-05 0.0013 18.9 4.7 1 23 569 592 569 592 0.96
11 14 1.4e-05 0.00092 19.4 2.4 1 23 596 618 596 618 0.99
12 14 6.8e-05 0.0046 17.2 0.6 1 23 624 646 624 646 0.98
13 14 2.2e-06 0.00015 21.9 2.6 1 23 652 674 652 674 0.98
14 14 0.0023 0.15 12.4 1.2 1 23 680 702 680 702 0.97

Sequence Information

Coding Sequence
ATGGAGGAAATATGCCGGGTTTGCCTGGGCCACTACGATGACATGGTCGACATATTTGCGGGAACGCTAGGATCGGGTCCTTCGATTCCGGACATGATTGCCGAGTGGTCCGGCTACCAAGTGGAGAAAGGCGACTCGCTGCCCGAAAGTATATGCTTAGGTTGCTTGGAAGATGCCCAGAAGGCAGTCGAGATCCAAGAGACTTCCCAGATGGGACACCAGTTCCTATGCCAAGTCAAGGAAGTCGAGCGCATCGGGAATGATTTGCGAAAGGAGGAATACTTTACAATATCAGACTCTGAGAGCGAGGGATCAAGAGCTGGCCACCCAGTCAAGGACAAAACATTCGGGGAAAAGGaatcaaataaagaaaataatgttCAGCAATTTTATACCGAAACTGTGGAACTAAACTCTTTGGAGGATGAGATGTCACTCGGCCAAACTGATCAATCCGTGTGCCAGTTCTCGGAGGACAGTAACAATGAGATATCAATTGGTGAACTTGATCAATCAAAGGGCTACGCTGAAGGTGAAGTCGAAGTCTGTGAAATATCAGACGACGAAACTAAGTCATCAGATTGTCAAATTCAAGAGGATGAGAAGAGTGAAAAGACAGTCGGGAAAGATGATCAACCCCATTTTAGAATTGAAAATGATGGTATGGATCTTGGTAGCCCGAAGACCTCTGACAATGAAGAGCGACCTCACAAGTGCCCCGTCTGTGCTAAAACCTTTGCACGCTATTgtagttttaaaaatcacCTCAGGGGCCATGAGGAGGACCCTGACTCTGCATCATATCATAGTACTGACACTCCAAGTGACAATAGTAGACGACCACATAAGACGGATCAACCGCAgggatttattaaaaatgacaCTTCTTCTAAGTCGGATGACCTATCTAACCGTCCAAACCAAGCAGGTCCAGAGGCCTACAGGAAGGTTCGATCGGGTGAGCGCCCATATAAGTGTAATCTTTGTCAGAAGGATTTTGTGCGAAAAGCTGGTGTAATAGTACACTTGCGTGTTCACACGGGCGAACGACCCTTTAAATGTGACCTATGCCCCAAGGCATTTAAGCAACAGGTTGACCTAAACCGACACATCTTGACCCACACAAAGGAACGACCGCACAAGTGTAACCTCTGCGATATGGCCTTTACGCATCCCTCTGCCCTCAAGGTTCATTACCGCGATCACAGAGGAGAAAGACCATTTAAATGCGGTCGTTGCCCGAAAACTTTTAGGTATAATTCGTGTTTAAAAACACACATCCGTGAACACACGGGGGAACGTCCGTATAAATGTGACAAATGCCCGCAGGCTTTTAAGGCACCACAAGATTTGAGGCGACACATCTGTAGTCACCCAAGGAAATTGCAGTTTAAGCGAATTAAAAGTCTTAATCctcaaaaaaaacacatgTTCCAGTGTGTGCAGTGTCCTAAGATTTTTCGGTCGAAAAGTGTATTGAGAGTGCACCTACGGGTGCACACGGGAGAACGTCCATTTGAATGTGATAAATGCACCAAATCTTTTAAGCACAACATCGACCTAAAGCGACACATTTTAACCCACACAACGAAGGGGCAATACAAGTGTCAGCAGTGCGACATGTCCTTTGCGCGTCACTGGTGCCTCAATGTTCACATGCACGTTCACACGAGAGAGAAACCTGTCCACTCGACAGAAAATCCTTATAAATGTGATCAATGCGACAGATCTTTTAACAAAGAATCCAGTCTCAGGCGACACACGACGATGTGTCACAAGAAAATATTCAAGTGCTTACATTGTACCATTGTTTTTACGGAAAAAAAGAATCTGGAGGAACATGTAAGGACTCATACACGTGAAAAACCATATAGTTGTGATCAATGCCCAAGGACATTTAAGTTTATGCCATCTCTTATGGCGCACAAACGAGTACACGTAGGAGAAAAACCGCATAAATGTGCTTATTGTCAGAAATCATTTGCCTATCAAGCCTCTCTAACGTCGCACATGCAGTCTCACTCCAAGTTGCGGACGTACAAATGTATCCAATGCCTGTTAAGCTTTACGCACCTACCCGCCCTCGAGAAGCACATAAAGACCCACACGTAG
Protein Sequence
MEEICRVCLGHYDDMVDIFAGTLGSGPSIPDMIAEWSGYQVEKGDSLPESICLGCLEDAQKAVEIQETSQMGHQFLCQVKEVERIGNDLRKEEYFTISDSESEGSRAGHPVKDKTFGEKESNKENNVQQFYTETVELNSLEDEMSLGQTDQSVCQFSEDSNNEISIGELDQSKGYAEGEVEVCEISDDETKSSDCQIQEDEKSEKTVGKDDQPHFRIENDGMDLGSPKTSDNEERPHKCPVCAKTFARYCSFKNHLRGHEEDPDSASYHSTDTPSDNSRRPHKTDQPQGFIKNDTSSKSDDLSNRPNQAGPEAYRKVRSGERPYKCNLCQKDFVRKAGVIVHLRVHTGERPFKCDLCPKAFKQQVDLNRHILTHTKERPHKCNLCDMAFTHPSALKVHYRDHRGERPFKCGRCPKTFRYNSCLKTHIREHTGERPYKCDKCPQAFKAPQDLRRHICSHPRKLQFKRIKSLNPQKKHMFQCVQCPKIFRSKSVLRVHLRVHTGERPFECDKCTKSFKHNIDLKRHILTHTTKGQYKCQQCDMSFARHWCLNVHMHVHTREKPVHSTENPYKCDQCDRSFNKESSLRRHTTMCHKKIFKCLHCTIVFTEKKNLEEHVRTHTREKPYSCDQCPRTFKFMPSLMAHKRVHVGEKPHKCAYCQKSFAYQASLTSHMQSHSKLRTYKCIQCLLSFTHLPALEKHIKTHT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00602740;
90% Identity
-
80% Identity
-