Basic Information

Insect: Drosophila sucinea
Gene Symbol: ZNF131
Assembly: GCA_018150745.1
Location: JAECWP010000177.1:17249-26957[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 2.7 2e+02 2.7 3.9 3 23 286 308 284 308 0.91

2 14 6 4.5e+02 1.7 1.1 3 21 448 466 447 470 0.89

3 14 7.6 5.6e+02 1.3 3.4 3 23 493 514 491 514 0.88

4 14 0.086 6.4 7.5 0.2 1 21 559 579 559 583 0.91

5 14 0.0032 0.23 12.0 0.9 2 23 626 648 625 648 0.95

6 14 0.38 28 5.4 0.5 3 21 655 673 655 674 0.93

7 14 0.22 17 6.2 0.9 2 23 693 714 692 714 0.93

8 14 0.00094 0.07 13.6 3.7 2 23 727 747 726 747 0.97

9 14 6.4e-07 4.7e-05 23.6 2.2 1 23 753 776 753 776 0.96

10 14 0.00027 0.02 15.4 0.3 1 23 801 823 801 823 0.98

11 14 2.3 1.7e+02 3.0 1.6 1 23 831 855 831 855 0.89

12 14 0.0091 0.67 10.5 2.9 1 23 860 884 860 884 0.98

13 14 0.0046 0.34 11.5 2.5 1 23 892 914 892 914 0.98

14 14 0.00097 0.072 13.6 4.7 1 21 920 940 920 945 0.93

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	2.7	2e+02	2.7	3.9	3	23	286	308	284	308	0.91
2	14	6	4.5e+02	1.7	1.1	3	21	448	466	447	470	0.89
3	14	7.6	5.6e+02	1.3	3.4	3	23	493	514	491	514	0.88
4	14	0.086	6.4	7.5	0.2	1	21	559	579	559	583	0.91
5	14	0.0032	0.23	12.0	0.9	2	23	626	648	625	648	0.95
6	14	0.38	28	5.4	0.5	3	21	655	673	655	674	0.93
7	14	0.22	17	6.2	0.9	2	23	693	714	692	714	0.93
8	14	0.00094	0.07	13.6	3.7	2	23	727	747	726	747	0.97
9	14	6.4e-07	4.7e-05	23.6	2.2	1	23	753	776	753	776	0.96
10	14	0.00027	0.02	15.4	0.3	1	23	801	823	801	823	0.98
11	14	2.3	1.7e+02	3.0	1.6	1	23	831	855	831	855	0.89
12	14	0.0091	0.67	10.5	2.9	1	23	860	884	860	884	0.98
13	14	0.0046	0.34	11.5	2.5	1	23	892	914	892	914	0.98
14	14	0.00097	0.072	13.6	4.7	1	21	920	940	920	945	0.93

Sequence Information

Coding Sequence: ATGAATACGGGCGATCTGGACGATACTCATCTGTGCATAAAGTGTAATGCAACCATTTTGGGTCTTGCGAAATACATTGAGCACCGCAAAGGGAATTGCTCCACTTTGCAAAAGTCAACAGCTAGTCCATGCGGACTGGCAACTAGGACTGCTACAGCGACAATAACGTCGCCACCGATTATCAGTCGTACCAATTTGGATCATACATACGACGGTTTTCATTTCGCCGAGCCAGAAGCACCAAGCAGTTTCCTACGGAAAGCAACTGAAAGCCACGGCGGAAAAACGTCCAAGACGCTGACAGAAGCTTATGATCTTCCATATGAGCTAGGAGCTGATGTATTCTTTTCATCGTTGCAATTGCAGAGTGTTTCAACTGGTGGTAAGACTGTACCAGGTGGACATCGTGTAGACATCGGAAGATCTAAGGACGAAGACTGGCATGCTCCCCCGGGGGATCCTCTACTCAAGGCTCTACGGGATCATGACAATGCGGTATTTAAACCTCTTAAGTTTGAACACGATTCCCCAGAGCAGAGTGAGGAAGAGGAAGAAGAGGACGAGCCCGAGGATTTTGATGAGGAGATCGATGAAGATTATGATATGAGACGAAATTCTCCACCTGCAGTTCCAGCTACACATACCGGAGGTAAATGGAAGCCAGAGCATCGGCCGCAGTTGCGGCATCCTCACATGGAACGCATTTCACCCAATTGGGATGAGCCTGGAGAGGAATCATATGCCCATCCACCGGCGGAACATACTAAGGGCAAATGGATACCTGGTAGCAAGCAGCTGGAGTATCGCGAAAACATAGATCTCACTAAACTCGAACAATTCGATGACAGCTATTGGTGTAATATCTGTTGTCGTAGATTAAAGAGTCGCACAAATTTCGAGCAGCATCTGAAAAGTACCTTCCATTTAAAGAAGGCAGAAACAGAGTGTCAACTAGAACAGGCCACTCTTGGAACGGAGCTAACTTTAACTGAACAGTTTCCTGTGGGACTTCAGCAGACAAATGCAGATAAAGGTCAATCAAGTAGGCAGCGTCGTCCCAGTCGTCTCCGGTGTAATCTCTGCCGTCACAGCCTGCCACGACATTTGATTGGCAAGCACCTTATCTCCCACTATCACTATCGGCGACTTCAACAGCAAACGCAGCGCCGGCGGCAAAGCTCGCTCCAAGATATACTTACTCACATGGTCAGCATTGTAAGACAATCGCCATTTCAGTGCTTGCCCTGCCGCTTCTATGCCAACACAGAAGCACTTTTCCTAAGTCACTGGCAATCCGCAGACCATCGGGAAGTTACCGATCGGCTTGGGGGCACTTTCTGGTGCGATTACTGTCAGTTTGAGTGTAATTCAAATGAAGCCATGTGGGATCATTTCATGCAATCAACTCACAAGAATGTCATTTTATCCCTTAATCGCTCTGTGCCCGTTTACATAGCTCAAAGAAGACATCTTCACTGTTCTTGCTGCGGCATGCGCTTTCTCTACAATGCACAATTGCGTCGCCATTTTGCCTCCGAGCATCCTGGACTCGCGCCCACCGGAAGTGCTGCCGATGAATATCAGTGTCGTTTCCGTTGTCAATTTTGCCGATCTCCTCATCGTTCCCGAGTGGCCTTGCAGCGTCACGAGAAGTACAAACATCAATTTATGAGATACTACTGCGCGATTTGTCGACTAGAATTTGAAAGTCCAACGGAAGCTCGTCGGCACCGCAGTCTTATGCAGCATAGGATGAAAACTAAACCAAATAAGACGATTTCCCAGCCGGAGAAACAGATCGAACAGATGTTGTGCAAAGTTCTAGAAGACCCGTCTCCCAGTCCTTCTACCGGAAAGCGGCGGACTATTCGTAAGCAGTGCTCAAATTGCTCAGAAACTTTTGAGTCATCCCAACTGCTTGCCCAACATCGGACTAAGGCTCATCCCTCTGAGAATCATGGATGCCTTAGTTGTGGATGCAATTTCCCATCTGCTCAAGCCTTGGGAAGGCATACCCGAAGCTGCCAGCCAATATCCACATCCTCAACACAATCTCAACACAAACTCAACTCATGGCCTTGTGATAAATGCAGTTTTAGTTCTCAGTACAAATCGGACCTAATTTACCATCAATTTTTTCATACTCAAGGAAAGGCAATTGACAAAAATAAGCTGCTCCAATGTCCACTATGCACCAAACAATTTCGAAAACATTCGCTAAGGGATCATTTACGTAATCATACGGGCGAGAAGATATTTCAATGTCCCGAGTGTGGTCAAAAGTTTGCCAGGCGACACAATCTCAAGAATCACTTAACCAGTATGCATAGCCGCCCACTGCAAACAAGAGCAAAGGATCGAGTCCAAGACGGAGAAGTGAAGAGAGATCTAAAAAAGAAGTATCAATGTGGAATCTGCGGAAAAATACTAGCAAAAAAATTCTCCCTAAAATTGCACGAGATGAGCCATAATGCTAACGTCGATCGCAGTTTTCGTTGCCATTTCAAGGACTGCTCGTATTTGGGCTTAACCCAAGAAAATCTAAAAGTCCACTTAATATCACACTCCCAAGGAAGTTACAAATGTAACAAGGAAAATTGCAATTACGTAGGAAAGAGTGAGCTGCATTTAAGGAGGCACCTCAAGTCACATGTAACAGAGAAGACTCATTGGTTCTCCTGCGATCAGTGCGATTTTAGAGCTCGACTTAAGGGTCATCTTACCCGGCATTTACTACGCCACTCTGGAGCGAAACCACACAAATGTCCCTACTGTGATTTCCATTGCAGTACCATTGATAATCTGCGTAAGCACATTATTAAAACGGGCAAGCATCCTGGAAAGTATATTTATGAGTGCGACAAATGTCTGGATGGACAAAGTAATGAAATTTTCAAAAGTAACAGCTTTAAGGAATATCAAAAACATTTGACCATGCATTTAGCAAACTGA
Protein Sequence: MNTGDLDDTHLCIKCNATILGLAKYIEHRKGNCSTLQKSTASPCGLATRTATATITSPPIISRTNLDHTYDGFHFAEPEAPSSFLRKATESHGGKTSKTLTEAYDLPYELGADVFFSSLQLQSVSTGGKTVPGGHRVDIGRSKDEDWHAPPGDPLLKALRDHDNAVFKPLKFEHDSPEQSEEEEEEDEPEDFDEEIDEDYDMRRNSPPAVPATHTGGKWKPEHRPQLRHPHMERISPNWDEPGEESYAHPPAEHTKGKWIPGSKQLEYRENIDLTKLEQFDDSYWCNICCRRLKSRTNFEQHLKSTFHLKKAETECQLEQATLGTELTLTEQFPVGLQQTNADKGQSSRQRRPSRLRCNLCRHSLPRHLIGKHLISHYHYRRLQQQTQRRRQSSLQDILTHMVSIVRQSPFQCLPCRFYANTEALFLSHWQSADHREVTDRLGGTFWCDYCQFECNSNEAMWDHFMQSTHKNVILSLNRSVPVYIAQRRHLHCSCCGMRFLYNAQLRRHFASEHPGLAPTGSAADEYQCRFRCQFCRSPHRSRVALQRHEKYKHQFMRYYCAICRLEFESPTEARRHRSLMQHRMKTKPNKTISQPEKQIEQMLCKVLEDPSPSPSTGKRRTIRKQCSNCSETFESSQLLAQHRTKAHPSENHGCLSCGCNFPSAQALGRHTRSCQPISTSSTQSQHKLNSWPCDKCSFSSQYKSDLIYHQFFHTQGKAIDKNKLLQCPLCTKQFRKHSLRDHLRNHTGEKIFQCPECGQKFARRHNLKNHLTSMHSRPLQTRAKDRVQDGEVKRDLKKKYQCGICGKILAKKFSLKLHEMSHNANVDRSFRCHFKDCSYLGLTQENLKVHLISHSQGSYKCNKENCNYVGKSELHLRRHLKSHVTEKTHWFSCDQCDFRARLKGHLTRHLLRHSGAKPHKCPYCDFHCSTIDNLRKHIIKTGKHPGKYIYECDKCLDGQSNEIFKSNSFKEYQKHLTMHLAN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00555470;
90% Identity: iTF_00555470;
80% Identity: -