Basic Information

Insect: Drosophila sucinea
Gene Symbol: -
Assembly: GCA_018150745.1
Location: JAECWP010000126.1:72534-76938[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 13 4.5e-05 0.0033 17.8 0.5 1 23 169 192 169 192 0.96

2 13 0.0014 0.1 13.1 2.9 2 23 241 263 237 263 0.89

3 13 0.0074 0.55 10.8 0.8 1 23 373 396 373 396 0.93

4 13 0.058 4.3 8.0 6.4 2 23 445 466 444 467 0.94

5 13 0.004 0.3 11.7 0.7 1 23 522 545 522 545 0.88

6 13 6.5 4.8e+02 1.6 0.1 2 14 564 576 563 588 0.83

7 13 0.0008 0.059 13.9 3.5 2 23 596 618 596 618 0.96

8 13 0.15 11 6.7 0.9 1 23 702 725 702 725 0.95

9 13 0.00066 0.049 14.1 0.2 1 23 778 801 778 801 0.93

10 13 0.0011 0.082 13.4 2.2 2 23 851 873 850 873 0.97

11 13 0.0076 0.56 10.8 1.7 1 23 965 988 965 988 0.92

12 13 0.05 3.7 8.2 1.5 1 21 1040 1060 1040 1061 0.95

13 13 7.2 5.3e+02 1.4 0.6 1 12 1150 1161 1150 1174 0.66

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	13	4.5e-05	0.0033	17.8	0.5	1	23	169	192	169	192	0.96
2	13	0.0014	0.1	13.1	2.9	2	23	241	263	237	263	0.89
3	13	0.0074	0.55	10.8	0.8	1	23	373	396	373	396	0.93
4	13	0.058	4.3	8.0	6.4	2	23	445	466	444	467	0.94
5	13	0.004	0.3	11.7	0.7	1	23	522	545	522	545	0.88
6	13	6.5	4.8e+02	1.6	0.1	2	14	564	576	563	588	0.83
7	13	0.0008	0.059	13.9	3.5	2	23	596	618	596	618	0.96
8	13	0.15	11	6.7	0.9	1	23	702	725	702	725	0.95
9	13	0.00066	0.049	14.1	0.2	1	23	778	801	778	801	0.93
10	13	0.0011	0.082	13.4	2.2	2	23	851	873	850	873	0.97
11	13	0.0076	0.56	10.8	1.7	1	23	965	988	965	988	0.92
12	13	0.05	3.7	8.2	1.5	1	21	1040	1060	1040	1061	0.95
13	13	7.2	5.3e+02	1.4	0.6	1	12	1150	1161	1150	1174	0.66

Sequence Information

Coding Sequence: ATGGAAGGCATGGACCTGTGGACGTCAATGTTCTCCAATGATTTTGAGGAGGGTGAGGAAAGTGAGCAATATGGCAATGGAACGGGAACGGATGGCAAGCCACCGGCGGATACAGACGACATTATGGCTGAGGGTTACGATGATGATGCCGATGGCGATGATGATGAGGATGACCTTATGGAAACGGAGGATAATGGCGAAATGGAGGAATCCGATAGAAATGGCAAGGAAAAGGGACCTGAACCTGATGATGATGCCATTTTTGATTTCGAATTGGAACCGATTGTAAGCATTGCCGAACCCCTAACAACACCTCTAGCGCCAGCTGGTCCAACATCAACTCCAGTGCGTCCCATGCATCGACATTCATTGCCCGCTGGTGGCTCTATGCCGGGACGACCCAAGGAAATGCGTCTGTCCGGTGTTCAAATGCGTCCAACCACCTCCCAAATCAATGCTACCGATGAGCACGGTGTTCCCATTAACTACGAGCTGGGGGTAATCTATATATGCCCCGCTTGTGGTGCAGAATTCCGGCAACAGGACCAATGGAAGCGTCACATGAACCACATGCATCAGTTCAACACACGACGTGGCCTGAATTTTATGGCCATAGATAAGCTATATCAGCGCTGCCTGGAATGCAACAAACGCATTGCCATGCATAGTCGCGAGAATCTTCTCAAGCACAAATTCACCCATTTGCCATATCGTTGCACAAAGTGCTATATATGCAAACGGGAGTACAAATATAGACAAGATTTAATGGTTCACCTGCGAATGGTGCATTGTGAGGAGATTGTAAACATGATGCGAGGTGGATACTCTTCGGCGGGACGGAAGACACGTGTCCGAGAGCCACGCACCGAGCAAATGCATCGTAAGGAGTTCTGTCTCGATGATGACGAAGCCATTGAAGTGAGGAATGAAGTGCTGGAACCTGATCTGGATGACTCTAGTTTTGGCGTGTCATCCACTTCATTTATGGAAGACGACCAACCGCAAAACTCGACTCAACCTCACAACGCCATGTCGACGAAGCGAAAGCGAAGTAATCCTTCAGGCAATGGTGGTGGTGCTGGTGGCGCCACCGAATTGTGTGAAGATTACATACATTATATGTGTCCCGATTGCGGAACAGAGTGCGATAATCATGCCCAATGGAGCCAGCACATTGAGTTTGTTCATGATTATGTTAGTCGTCGGGGACTCAACTTCAGAAGCGTAGACATGCAGATGCAGTGCTTGGAATGCAAGCAGATTGTTACCCCCAACACGATTAAGACTCTGAGAGCTCACAAATTCAGCCATCTTCCGCAGTCCGAGTGGCTACGTTGTAAGCTGTGCTACAAGAGTTACACGGAGCATCATGAGTTGGTCTCCCATTTGTTAAAACATCACAATTTGGAGACATTGATACCAGGAGATGGAGAGGACCAATTGCCGAATTGTGCAGGAGATGACGAGGGAGGAGATGGCAACGAGATCTTCGATGATGGCGATGATGTCCGTAAACGTGGTGGACGCATAAGCAGCGATGATATCTATGAGCCGCACATCGATTACCTTTGTCCGCAGTGCGGCAAGGAGTTCATGGAGAAGAAACATTGGCGTACCCATGTCGTCCAAGTCCACGGCATGAACGACATAGCTAAGCTGAACTTTGAGATTATATCTGAGCGCCAGTTGAAGTGCACGGAATGCGAGAAGATCATCACGAATGCCTACGGCATACAGAATGCCCAGCAGCACAGGATAACACATTTGCCCTTTAAGGCCTATGCCAGATGTCGCAAGTGCCACAAGACGTATACGGATCGCAAGGGCTTAGTCAAACACTTGGCCACATATCATCGCGTGGGCTGGGAGGCAGGACGCAAGTCCGGAACGAGTGGTGATGCTGGAGGGGGTCAACCGGCTCTGGCGTCCAAGCAGCCACGAAAGCAAATCGTAACCGTGGCTAATGAAACCTATGAGATTATCTATTTGGATGAGGAGCCGAGCAACATTGAGGAGAATGATTTTGGTGAGCAAATGCAGGCGGATGATGATGAATATGCGCCTCCTCCGCCTCCACCTCCTCCTAATCCTCCTCCCCATCGATACAAGTGCTCGGATTGTGGATCACTGCACAGCACTCAAATGGCTCTCAAGATGCACATCAAAGAGGAGCATAGCTTAAGGGAATCCAAGCATCCTGCAATGAAATATGCCGAGTCTAAGGAAGAGGAAAAAAAGAAGAAAGCACCTGGACCATCGGCACCGTCGTCCTCTTCTACCCCAACCACTTCCATCCGTTCACCAGGTACCACAATTGAGCAAAATTACATTTTCCTGTGCCCTTCTTGCGGTGAGGAGTATAAGACGCAATTCGAGTGGCGACGCCACATCAACGAAGCCCACAACTTTGACAAGCGGGAGTATTTAAATATGCGACAGATGGACAAGTATCGATATCAGTGCACCCAGTGCAAGGATATTGTTTGCAACTCAAAATTGAAGGGACTGCAAGATCATCACTTCCGGCATCTGCCCTACCGTTTGTATCTCAAGTGTTTGGTTTGTGGCACTTGCTACAATCACAAGCCGAATATAGCAGCTCATCTACGGACACGTCATAATATCTTTGAGCGGGAGACACCTTGGCGGGAGCAGCGCAATAAACCGCAATATGCATACGTTCAATCCAAGGACCCAATCGATAAAGGAAGAAACAGCAGACCAGAGTCACCGTCACCAGTTGCCTCGTCATCGTCATCAGCAGTCTTGGTTATTGGTAGCAGCCGCACGCTAAAACCCCAACCAGGTGGATTGCCCACCCGACCCGCTGGTCTCAATACGCTGGAGGATAGCATTTCTTACCACAATGCCGTCGATCTGGACTTTATCACCTACTACTGTCCAAAGTGCAATCAGAATTTCGATTCACATGCTTTCTGGCGCAAACACATTGTGGAACAGCATAATTTCAATTGCCGGGAGGGTCTCAACTTCCGGCAGATCGACAACCATCACTACTTGTGCCTGGAGTGCTATAAACGCGTGACGGTCACCCACACTAAGGGCGCCATCGGTCAGCTGCAATCGCACAAGTTCCGTCATCTGCCCTATCGCTCCTTCAAATGCTTGACCTGCAATGGAGAATTCGTGCGCAAGCAAATGTTCTTTAAGCATCTGAACAGGGATACCAATAGATGCGATAATCGTCCCAGTGGCCTAGATGGCCCGGTCATTGACGATGAGGATCAGGAGGTGGCACAGAGCGCCAGCGAAGTGGTTACGGTTGAAGACGAGGAAGTGGATCCATCTGCGTATCGTTTAATGTGCCCGCAATGCGGTGACAATATCGACACAAGCAGCAAAGCCGTCTGGCGTGAGCACATTAACATCTACCACGGTCTGGGCAAGAAGGAACTCTTGCATATGCGAAAAGTTGGCGACGATCTCTATCGTTGCTACGACTGCGACGAGGAGCTGCAGACGAAGAAGCTGCGTGTGCTTCAGCAGCATCGTTTCCGACATCTGCCTTTTGCTGCCTACATACGTTGCTTGCTCTGCGAGAATCCGGAGGGCGATGATAGCGATGCTGCAGCAGGTCTGCATAGTATGCGGGAATTGCAGCAGCACATACGGGAACATCACCCGACCATTGAGGAGAGCGATGAGCAAATGCAGAGAGTGCGTCAACAGGCCGCCGAAGAGGAGGCTGACGAGGACAGTCATTTGGAGAACGAGACCGCGGCCAGTTCAGAACATCACTCGACTTTGACTCATAATCCTAATTTAACTATAGAACTGACAATTTAA
Protein Sequence: MEGMDLWTSMFSNDFEEGEESEQYGNGTGTDGKPPADTDDIMAEGYDDDADGDDDEDDLMETEDNGEMEESDRNGKEKGPEPDDDAIFDFELEPIVSIAEPLTTPLAPAGPTSTPVRPMHRHSLPAGGSMPGRPKEMRLSGVQMRPTTSQINATDEHGVPINYELGVIYICPACGAEFRQQDQWKRHMNHMHQFNTRRGLNFMAIDKLYQRCLECNKRIAMHSRENLLKHKFTHLPYRCTKCYICKREYKYRQDLMVHLRMVHCEEIVNMMRGGYSSAGRKTRVREPRTEQMHRKEFCLDDDEAIEVRNEVLEPDLDDSSFGVSSTSFMEDDQPQNSTQPHNAMSTKRKRSNPSGNGGGAGGATELCEDYIHYMCPDCGTECDNHAQWSQHIEFVHDYVSRRGLNFRSVDMQMQCLECKQIVTPNTIKTLRAHKFSHLPQSEWLRCKLCYKSYTEHHELVSHLLKHHNLETLIPGDGEDQLPNCAGDDEGGDGNEIFDDGDDVRKRGGRISSDDIYEPHIDYLCPQCGKEFMEKKHWRTHVVQVHGMNDIAKLNFEIISERQLKCTECEKIITNAYGIQNAQQHRITHLPFKAYARCRKCHKTYTDRKGLVKHLATYHRVGWEAGRKSGTSGDAGGGQPALASKQPRKQIVTVANETYEIIYLDEEPSNIEENDFGEQMQADDDEYAPPPPPPPPNPPPHRYKCSDCGSLHSTQMALKMHIKEEHSLRESKHPAMKYAESKEEEKKKKAPGPSAPSSSSTPTTSIRSPGTTIEQNYIFLCPSCGEEYKTQFEWRRHINEAHNFDKREYLNMRQMDKYRYQCTQCKDIVCNSKLKGLQDHHFRHLPYRLYLKCLVCGTCYNHKPNIAAHLRTRHNIFERETPWREQRNKPQYAYVQSKDPIDKGRNSRPESPSPVASSSSSAVLVIGSSRTLKPQPGGLPTRPAGLNTLEDSISYHNAVDLDFITYYCPKCNQNFDSHAFWRKHIVEQHNFNCREGLNFRQIDNHHYLCLECYKRVTVTHTKGAIGQLQSHKFRHLPYRSFKCLTCNGEFVRKQMFFKHLNRDTNRCDNRPSGLDGPVIDDEDQEVAQSASEVVTVEDEEVDPSAYRLMCPQCGDNIDTSSKAVWREHINIYHGLGKKELLHMRKVGDDLYRCYDCDEELQTKKLRVLQQHRFRHLPFAAYIRCLLCENPEGDDSDAAAGLHSMRELQQHIREHHPTIEESDEQMQRVRQQAAEEEADEDSHLENETAASSEHHSTLTHNPNLTIELTI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00503590;
90% Identity: iTF_00555443;
80% Identity: -