Dsuc013278.1
Basic Information
- Insect
- Drosophila sucinea
- Gene Symbol
- -
- Assembly
- GCA_018150745.1
- Location
- JAECWP010000001.1:21334288-21337415[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 17 0.095 7 7.3 7.3 2 23 218 240 217 240 0.94 2 17 4.5 3.3e+02 2.1 0.0 1 23 248 273 248 273 0.91 3 17 0.037 2.8 8.6 2.1 2 23 284 305 284 305 0.93 4 17 4.8 3.6e+02 2.0 0.4 3 23 346 367 345 367 0.91 5 17 0.0064 0.47 11.0 0.9 1 23 373 395 373 395 0.95 6 17 0.004 0.3 11.7 1.6 1 23 403 426 403 426 0.98 7 17 3.9e-05 0.0029 18.0 0.4 2 23 431 452 430 452 0.97 8 17 0.011 0.78 10.3 5.1 1 22 500 521 500 524 0.91 9 17 8.4 6.2e+02 1.2 1.4 3 21 531 549 531 550 0.92 10 17 0.0023 0.17 12.4 1.9 1 23 569 594 569 594 0.96 11 17 0.0049 0.36 11.4 1.7 2 23 619 641 618 641 0.94 12 17 0.0079 0.58 10.7 0.2 2 23 647 669 646 669 0.92 13 17 0.02 1.5 9.4 0.3 2 23 673 695 672 695 0.94 14 17 1e-05 0.00075 19.8 3.0 1 23 701 723 701 723 0.98 15 17 0.0068 0.51 10.9 2.7 1 23 727 750 727 750 0.93 16 17 6e-05 0.0044 17.4 0.8 1 23 756 779 756 779 0.96 17 17 2 1.5e+02 3.2 0.2 1 23 783 811 783 811 0.83
Sequence Information
- Coding Sequence
- ATGGAGAAAAAGTTACAAAATTGTCTGCATTGTACAGTGTATAATCCGGAATTGAAATACCATGAAATTTTCAAAGGACTTGGCGCAGAAATTGGATTGCAACAATTATTGGCAAATCATTTCCAATTCGATGTAACAGAGGACTCCTCGAAGCCGCAGCTGCTTTGCGAGAGGTGCGTCAACAGTTTGATAAGATTCTTTGACATAGATGAACTGGAACGGGAACAGCATGCACCAAGGCCAGGAGAAAGTAATTGCATCAAGCCCAGTGAAAAAACTAAAGAAAAAGATGTGGGAAAACCAATCATAGATGAGACCTGCATTTATGATATCATATTCAAATCGGACGAAGATGTATCGGCGGTGGAAGAGGAGAAAGGGGAATACGAAGTCACCAGCAAGTCAGAACACGTGGGAAATGAGGATAGTGTGGACGACCGGGTAACAGTGATTCAACTGGAGAGTAATGAGCAATTAGTGGATTTGGATGTAGAAGCAGAGGACGACGAAGATGGTAATAAAACAGACAGCAATGTGATAATACTAAATTTTGTTGAGATTAAAGAAAAGGATGACATTGATGATTTATATGCCTATTTCGCCACTGCGGTAAAGACGAACTTTGAAAACTTGTCCTTTGAATGGAGCACCGTATGCAAACATTGCTCAGTGTCTTGCTCCAACTATCAGCAGCTATTTAACCATATGCTTCATAAGCACAAGGACGTTAAGGCTCATTCCTTTGACTGTCCCATCGAGGGGTGCGTGGCGCAACTGAAGGATAAACAATATCTGGCCATGCATTTGGTTATGTTGCATGGTCCAGTGGCAGAAATTCCCATCTATGGCAGTTGTCCGGAGTGCAAATTGACCTTTTCCAATATTCTGCAATATAATAAACATTCCTGTGCCCATGTGATTAAGAAGAAACGGGGAATCCAACTCTATTGCGAAATGTGTTCCATTGAGTTTCCCTCTTGGAAACGTTTTAATTTCCATAATCAATTCCATTTAGAGAGACATCGACCTCGAGCATGTTTTGTCTGCAACTATGCGGACACCAATATAAGTGATCTCTTCCAGCATTTGCATTATGCCCATGAACCGGAGGGCACATTCTTTTGTAATCTCTGTGATCGCACATTTCGTGATGAGGCCGTCTTCTTGGAGCACAACAAATCCCATTCCAATGTTAGCAGCAACACTTACACTTGTGTTGAATGCTTCAGCAGTTTTGACACACGGAGTCGTTTCAATGGACACATGCGCTCTATGCATGGCAGCTTCATCACTTGCGAGATCTGTTCCCGTGAATTTGCAAGCGAATCCACTTACAATGTGCATATGAAGAAGCATTTGATCATTGAACGGGATGTCCATATATGCCGGAATTGTGGCCAACTTAGCGAACATGAGAATAGAATGCAGCAGCATAAACTAAATGAATCGACAAATTGTCATCAGGCTGAGATCTATACGCATCTCTTGCGTAATGCTTATATATGCGAAAATTGTTCATGTTATTTTCGTAAGAAATCGGATTTACATAAGCATCGTCAGTCAGGCGTACATGATGATGGATTATTTTGGTGTCACCCTTGTGCCAAGGAATTCACCGATATGAAAGTTTATCGTCATCATTTGCGAAACTTTCAACAACTCAAATCTGACACGGAACACAGGAAATTGGAAATATGTTTGTATTATATGTGTGATCAGAAAGATTGCTTCGAATCTTATACGAATTGGAACTCCTTGTATACGCATAAGCGACGTACCCATAAAAGTGACCATAAGCCATTAAAAGTGGAACCATCCACATCGAAATCTATTGAAAAGCTGAAACCGGAATGGCAATGTCAATTTTGTGACAAGGAATGCCGCTCTAAAATGTCCCTTTCTGTTCATGTGGCACGCAGTCATAATAATGATAATGTGGTCTGTTCCATTTGCAATTCGTCGTATAAGGACCAAGCGGCTTTGGATAAGCATCATGCCTATTGGCATGAACCCATAGAGTGTCCCAAATGCTTTAAAATTGTGAAGAATCGTCGCAATTATGATACCCATGAGAATGTCGTTCATTCGGATAATAAACGTTATTCATGTGAGATTTGTGATAAGGGTTTCTATCATAAAAGTGAAATGAAGTCCCACCAGAAGCTTCATTCCCAGTCGTACAGTTGTAAACATTGCAGTTTTACCACAAGAAATAAAACTTCTTTATCAGTTCATGTTTTGGGTCAGCATTTTAAGCGTTTCGCTTTTGCCTGCAAGATGTGCTCGAAGCGGTTTGGTCGTCGTCAGGGATTGGCTACCCATATGCAGCGTGTACATGGCACCAAGTATGTCTGCCAGGAATATTTTACGGGCGGTTGCAATCGTAGTTTTGCGTCAACTTTGATATTGAGTCAGCATGTTAAGAAAGTCCATAAGGGTACCATATTTCTACCTGATATGCTAGAGGAAGAAATGGACGAGCAGGATGATTTGGAAGAGGAGGAGGACGAGCTCGATCTGGAAGATGATGGTCCTTCTTCGTCCAAGAAACGTTGTTTTCAAATAAATGATACCAAAATTGAGTTTATTGAAGAGGGAGCATACGATAGTCAGGAATTTATAGATACTGACCACCAGGAGGTAGAAGAAGTGCAAGATGAGAGGTAA
- Protein Sequence
- MEKKLQNCLHCTVYNPELKYHEIFKGLGAEIGLQQLLANHFQFDVTEDSSKPQLLCERCVNSLIRFFDIDELEREQHAPRPGESNCIKPSEKTKEKDVGKPIIDETCIYDIIFKSDEDVSAVEEEKGEYEVTSKSEHVGNEDSVDDRVTVIQLESNEQLVDLDVEAEDDEDGNKTDSNVIILNFVEIKEKDDIDDLYAYFATAVKTNFENLSFEWSTVCKHCSVSCSNYQQLFNHMLHKHKDVKAHSFDCPIEGCVAQLKDKQYLAMHLVMLHGPVAEIPIYGSCPECKLTFSNILQYNKHSCAHVIKKKRGIQLYCEMCSIEFPSWKRFNFHNQFHLERHRPRACFVCNYADTNISDLFQHLHYAHEPEGTFFCNLCDRTFRDEAVFLEHNKSHSNVSSNTYTCVECFSSFDTRSRFNGHMRSMHGSFITCEICSREFASESTYNVHMKKHLIIERDVHICRNCGQLSEHENRMQQHKLNESTNCHQAEIYTHLLRNAYICENCSCYFRKKSDLHKHRQSGVHDDGLFWCHPCAKEFTDMKVYRHHLRNFQQLKSDTEHRKLEICLYYMCDQKDCFESYTNWNSLYTHKRRTHKSDHKPLKVEPSTSKSIEKLKPEWQCQFCDKECRSKMSLSVHVARSHNNDNVVCSICNSSYKDQAALDKHHAYWHEPIECPKCFKIVKNRRNYDTHENVVHSDNKRYSCEICDKGFYHKSEMKSHQKLHSQSYSCKHCSFTTRNKTSLSVHVLGQHFKRFAFACKMCSKRFGRRQGLATHMQRVHGTKYVCQEYFTGGCNRSFASTLILSQHVKKVHKGTIFLPDMLEEEMDEQDDLEEEEDELDLEDDGPSSSKKRCFQINDTKIEFIEEGAYDSQEFIDTDHQEVEEVQDER
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00555334;
- 90% Identity
- iTF_00555334;
- 80% Identity
- -