Dsuc016355.1
Basic Information
- Insect
- Drosophila sucinea
- Gene Symbol
- RREB1
- Assembly
- GCA_018150745.1
- Location
- JAECWP010000138.1:2526518-2532737[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 11 0.025 1.8 9.2 0.8 1 21 88 108 88 110 0.93 2 11 0.00023 0.017 15.6 0.2 1 23 120 142 120 142 0.98 3 11 0.5 37 5.1 6.3 2 19 289 306 289 308 0.97 4 11 0.003 0.22 12.1 0.0 1 23 482 504 482 504 0.97 5 11 3.3e-05 0.0024 18.2 2.1 1 23 514 536 514 536 0.99 6 11 0.00057 0.042 14.3 2.0 1 23 542 565 542 565 0.97 7 11 0.002 0.15 12.6 2.0 1 23 736 759 736 759 0.95 8 11 5.9e-05 0.0044 17.4 0.3 2 23 1026 1047 1025 1047 0.97 9 11 0.1 7.4 7.3 6.3 1 23 1053 1076 1053 1076 0.97 10 11 0.0058 0.43 11.2 0.5 3 23 1266 1286 1264 1286 0.96 11 11 0.00092 0.068 13.7 4.8 1 23 1292 1314 1292 1314 0.99
Sequence Information
- Coding Sequence
- ATGCTGGCAGCAACAGCAACAACAACTACTTCGACAGAAATGGAACACGGCGCTGCCGATGCCAATTCGCTGCGCAAGAAATTCCGCTTGAACCGCAGCAACAGCAGCAGTCTAATGAATGGTGAACTATCCGAATCGGGATTTGTCGATGGCAGTGCACACAGTGGCTATCTGATGGGCAATAGCAATGCCTCCGCTGTTGCTGCCGCTGCCAGTCTTTGCATGTCATCGTCCAGTGCTGGCGGCGATGAGCACATGAAATATCTATGCCCCATCTGCGAGGTTGTCTCGGCCACGCCCCACGAGTTTACCAATCACATCCGATGTCATAATTATGCCAATGGCGATACCGAAAATTTCACCTGTCGCATTTGCTCCAAGGTACTATCCTCAGCCTCATCCTTGGATAGGCATGTCCTTGTCCATACGGAGGAGCAAGTGGAGCTCGAAGATGAGGATGATGAACAAGAAGCAGCTGGAGCCATGACCATGGAGGACACCATGCCGCTAATAAAGCAAAAACGTCGTCTCAAGACGACCATCATTAACAACAACAACAACAACAATAAAATAATAAACAACAATGATGATGATGATGATGAAGGAGAAGAAGCCGGCAAGCATGGAGATGACACGGATGGGGATGACAATACAGATGCGGATGATGCTGATGAGGATCGCCGGACAGAAGTGGAAGTGTCCATCACTAGCACACCCGATGTGGCCGCTCTATTGGCTGGAGCCTCGCGATCAGCATCTCCCTCACCACCCCTAATCAGTTGTCCCGTCTGCTGCATGAGCGAATTCGAATCCCTGCCCAGTTTATGCCAACACTTGGATCAGCAACATTCCGATATTTTGGCCAAGTGTCGCGAGTGCGATGTCATCTTTTCCAGCCACAAGCAATTGCAGAAGCATTGCTGTCGCGGCTCAACCGGCTTACCTCCACTCCTCAGAGCGAGTAGCTCCCCCCTGCATGGTGAGGATGAGGATGAGCGGAACGACAATGCGGAGGAGAGGCAAGCCAATCATCATCGTGACAATGGTTGCCATGGCCACGTCGACGACGAAGACGACGACGATGAAGCCGAGGTGGAAAAGGAAGCCGAGGCTGAGGCCAAACAGCGAGACGATTTCTTTCATCATCTGTATCTGAAGAGCAAAACAGAAGCCATGTCCGAGGATAACAATGAATTAATGGCAGCCACTTCGCCACCATCCCCGATCAAGCATGAGCCGAACGACAGCAAGGATCTGGCTGACATCCAGAGCATTCTCAACATGACCAGCTCCAGTTGCACGTCGAGTTTCCTGCGGAACTTTGAGCAATCCGTGAACACGCCCTGCTCGTCCAGCCAGTACAGTTTGGATGGACGCGATCAGGAGGAGGAGGCACAGGATGCCTTCACTTCTGAGTTTCGTCGCATGAAATTGCGCGGAGAATTCCCGTGCAAGCTCTGTCCAGCGGTGTTTCCCAACTTGCGTGCCCTCAAGGGACACAATCGCGTGCATTTGGGGGCGGTGGGACCCACGGGACCCTTCCGCTGCAACATGTGCCAGTTCTCCGTGTGCGACAAGGCCGCCTTGGTGCGTCACATGCGCACCCACAACGGCGATCGTCCGTACGAGTGTGCCGTCTGCAATTACGCCTTCACCACCAAGGCCAATTGCGAGCGGCATCTGAGGAATCGTCATGGCAAAACCAGTCGCGAGGATGTCAAGCGGGCCATTGTCTACCATCCGGCCGAGGATGCCAGCTGCGGTGAGGGTGAGGGCGGCAAGCTCCGCCTGAATGAGGCGGATGAGAGTTATCGTTCGGCATCGCCGCCACCCCTCGAGGTAGCTGCCACTGCCTCCCAGCTGAAGCACATGTTGATGAGCGAACCCAGCGTCGTCCAGAGTGTCCAGCAGCCGCCACTTAAGATTCAAGTCAAGAGCCTGGATCAATTGGTGGAGAAGTCAACGCCCATAAAGGTCGCTCCATCGCCATCAACAACTCCACCGCCAGCGGCATCCTCTGGCGCAGCAGCAACAGCAGAGAAGCTGCCTCCTCCATCGGCGCAGCAGCAGCAACAAATGAGTCCGTCCAGCAATCGTCTGTCCCTGCCGCCCCTCTCTCTGCCTGGTGGCCCCGTCAAGATGGTCATCAAGAACGGCGTCCTGATGCCCAAGCAGAAGCAACGTCGCTATCGCACCGAGCGGCCCTTCGCCTGTGAGCACTGCTCGGCGAGATTCACCTTGCGATCGAACATGGAGCGACACGTGAAGCAGCAGCATCCGCAATTCTATGCCCAGCGCCAGAGGAGTGGCCACCATGTGATGCGTGTGAAATATGCCATTTTGGCGCAACAATTGAAGGCTCACAAGAATACGGATTTGCTGCAGCAGGCGCTGGCCCATGGGTCCAGCAGTGTGGCGGCCTCTTCGCATCTGTTGAACTTCAATTATGCTCTGGCCAATGGCAATGGGAATGGGAATGCCAATGTGGTGTCAGCAGCACTTGACCTGGACATGGAGAAGAAGAAGAAGCTGGTGGAGGAAGAGGTCGAGGTGGTGGAGGATGAGCAGCAGTCACGCAAAGATTTGCCACAAACCATCGAGACCTTGGCCAGCAATGAGGCGGCCAAGAAGGTGGCCGAAACCATATTGGAGCAGGCCATTAAGGCGGGCAAACCCATGGCCATGCCAGTAGAACCAGTGGAACCAGTGGTCGCTCCCCATCAGCCGCCATCGTCAATGAAATCGATGATTGCTCAAGTTGAATCCGTGGCCAAGTCACTGAAGGATGTGGCCAGCTCACCGTTCAACAAAGATGAATCTCCGCTCTCCGACTTGGTGCCGGTGTCCAAGCTGGTGGACAATGCCACCAGCAATCAGTCGATGCAAAGCTTCACCAGTTACTTTCGTCCCAGCGACGTGGCCAATCACATGGAGCAGAGCGATGAGGAGGGACTCGTTGCCTCCGGCAGTGCCAGCGAGAGCAACAACTCCGGCACCGAGGATGTCACCAGCAGCAGCAGCAGTGGCCAGGAGCCCAAGAAGAAATCAGCCTACAGTCTGGCTCCCAATCGTGTCTCCTGCCCCTACTGCCAACGCATGTTCCCCTGGAGCAGCTCACTCAGGCGTCACATTCTAACCCACACCGGGCAAAAGCCCTTCAAATGCTCCCACTGCCCATTGCTCTTCACCACCAAAAGCAATTGTGATCGCCATCTGTTGAGGAAGCATGGCAATGTCGAGTCGGCCATGTCCGTGTATGTCCCCACCGAGGATGTGAGCGAGCCGATTCCGGTGCCCAAGTCGGTGGAAGAGATCGAATTGGAGGAGCAGCGACGGCGGCAAGAGGCGGAGCGTGAAAAGGCCGAATTGGAGCGCGAACGAGAACGTGAACGCGAAAGGCAATTGGAGCGAGAGCGGGAAAAGGAGCGAGAGCGTGAACGTGAACGGGAACGTGAACATGAGCGAGAATTGGAATTGGAGCGAGAGCAGCAGCTTATGCAACAATTGGCTGCCGCTGCTCAACTAAGTCAGCAAATTGCCTGCCATTTGTGTGAATGTTCGTTTAGCGAGCGTTTGCAGTGCTTGGATCACATCAAACAAATGCATGCCCATGAGTTTGCCCTGCTTCTGGCCAAGGGGGCCATCGAAACGGAAGAGCCCACAGCGAATCCAACAACAGGAGCAACAGCAGCTGCTCACTCCGATGATGAGTCCATGGGCATTGGCAATGGCCGTGGTGCTAGTTCCGGTTCCGGATCGGGTAAATATCCCGATTACAGCAATCGCAAAGTCATATGCGCTTTTTGTGTTCGTCGCTTCTGGTCCACCGAGGACTTGCGCCGTCATATGCGCACGCATTCGGGTGAGAGGCCATTTCAGTGCGAGATTTGTCTGCGCAAGTTCACACTGAAGCACAGCATGTTGCGCCACATGAAGAAGCATAGTGGACGGTCTCATAATGCTGGTGAGATGCAAGGTGGATCCGATTGTTCTGATGATGAGCAAATTATGACCACAACAACAGGAGCAGCAGCAACAACAACTACACCGCCACCCACACCCACCCTGCCTAATAATAATAATAATTCTCATACAAACAACAACAATAACAACAACAACAACAATAATACGAACAACAACAACAATAATAACAAATTGGGACTACGTCTACCGAAACTGCATGAGCTACTGGACAAGGCCAACGAATGGCGGGCCAGTCGTTTGGGCGAGCACAAAGAGAATCTGGGCGAAGCGGCCACGACACCGGGAGCAACTGCATCCGCTGTGGCCGGTTCAACGGATCTCATTGGCAATCTGTTGGGCATTAGCGATCAGGGTATATTGAATAAGTTGCTCTCGTCCGCCGATGAGGCAGCCAAGTTTCTGGGAGTGGACAAGTAA
- Protein Sequence
- MLAATATTTTSTEMEHGAADANSLRKKFRLNRSNSSSLMNGELSESGFVDGSAHSGYLMGNSNASAVAAAASLCMSSSSAGGDEHMKYLCPICEVVSATPHEFTNHIRCHNYANGDTENFTCRICSKVLSSASSLDRHVLVHTEEQVELEDEDDEQEAAGAMTMEDTMPLIKQKRRLKTTIINNNNNNNKIINNNDDDDDEGEEAGKHGDDTDGDDNTDADDADEDRRTEVEVSITSTPDVAALLAGASRSASPSPPLISCPVCCMSEFESLPSLCQHLDQQHSDILAKCRECDVIFSSHKQLQKHCCRGSTGLPPLLRASSSPLHGEDEDERNDNAEERQANHHRDNGCHGHVDDEDDDDEAEVEKEAEAEAKQRDDFFHHLYLKSKTEAMSEDNNELMAATSPPSPIKHEPNDSKDLADIQSILNMTSSSCTSSFLRNFEQSVNTPCSSSQYSLDGRDQEEEAQDAFTSEFRRMKLRGEFPCKLCPAVFPNLRALKGHNRVHLGAVGPTGPFRCNMCQFSVCDKAALVRHMRTHNGDRPYECAVCNYAFTTKANCERHLRNRHGKTSREDVKRAIVYHPAEDASCGEGEGGKLRLNEADESYRSASPPPLEVAATASQLKHMLMSEPSVVQSVQQPPLKIQVKSLDQLVEKSTPIKVAPSPSTTPPPAASSGAAATAEKLPPPSAQQQQQMSPSSNRLSLPPLSLPGGPVKMVIKNGVLMPKQKQRRYRTERPFACEHCSARFTLRSNMERHVKQQHPQFYAQRQRSGHHVMRVKYAILAQQLKAHKNTDLLQQALAHGSSSVAASSHLLNFNYALANGNGNGNANVVSAALDLDMEKKKKLVEEEVEVVEDEQQSRKDLPQTIETLASNEAAKKVAETILEQAIKAGKPMAMPVEPVEPVVAPHQPPSSMKSMIAQVESVAKSLKDVASSPFNKDESPLSDLVPVSKLVDNATSNQSMQSFTSYFRPSDVANHMEQSDEEGLVASGSASESNNSGTEDVTSSSSSGQEPKKKSAYSLAPNRVSCPYCQRMFPWSSSLRRHILTHTGQKPFKCSHCPLLFTTKSNCDRHLLRKHGNVESAMSVYVPTEDVSEPIPVPKSVEEIELEEQRRRQEAEREKAELERERERERERQLEREREKEREREREREREHERELELEREQQLMQQLAAAAQLSQQIACHLCECSFSERLQCLDHIKQMHAHEFALLLAKGAIETEEPTANPTTGATAAAHSDDESMGIGNGRGASSGSGSGKYPDYSNRKVICAFCVRRFWSTEDLRRHMRTHSGERPFQCEICLRKFTLKHSMLRHMKKHSGRSHNAGEMQGGSDCSDDEQIMTTTTGAAATTTTPPPTPTLPNNNNNSHTNNNNNNNNNNNTNNNNNNNKLGLRLPKLHELLDKANEWRASRLGEHKENLGEAATTPGATASAVAGSTDLIGNLLGISDQGILNKLLSSADEAAKFLGVDK
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -