Basic Information

Gene Symbol
-
Assembly
GCA_018150745.1
Location
JAECWP010000095.1:505792-508248[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 12 0.065 4.8 7.9 5.9 3 23 281 301 279 301 0.96
2 12 0.0026 0.19 12.3 0.5 1 23 307 332 307 332 0.94
3 12 0.0008 0.059 13.9 0.5 1 23 339 364 339 364 0.95
4 12 0.00018 0.014 15.9 2.4 1 23 373 395 373 395 0.97
5 12 8.7e-05 0.0064 16.9 0.1 1 23 402 424 402 424 0.97
6 12 0.007 0.52 10.9 0.5 1 23 430 452 430 452 0.97
7 12 0.15 11 6.7 1.8 1 23 458 481 458 481 0.96
8 12 0.011 0.85 10.2 4.5 1 23 487 509 487 509 0.96
9 12 0.00032 0.024 15.1 2.4 2 23 516 537 515 537 0.96
10 12 1.5e-05 0.0011 19.3 1.5 1 23 629 652 629 652 0.96
11 12 0.041 3.1 8.5 7.1 1 23 658 680 658 680 0.94
12 12 1.9e-06 0.00014 22.1 2.4 1 23 686 708 686 708 0.99

Sequence Information

Coding Sequence
ATGAATGAGGGAAGTGCGTTATCATCGTACTCCATTCACTCGGTGTGCCGCATCTGTTTGAATCATCTGCAGAATGGCCCCGTTTTCGATCTATTCCTTATACCCGGACTGGCCAAGAAACTGTGTGTGTGCACATCGCTGTCGGTGGAGCAGCAGGATGGATTCCCCCGGAATATTTGCTGCACCTGCCATTCCAAATTGGATGATATGCACCAGTTTCAGAAATTATGCGTCGACTCGGTGCAGAAATTCCAGGAAATGTTGGCCAACAATGCATTCCAGACCAGTTTCGATGTGCTAGATCCCAGTGTGACGGCTCAGGATATGCCAACGCAAGAAGATGACGATCACATTAACTTTGATCCGTTGTTGAATTCCAAAATAGAAATCATAGAGAATGAAGAGGATGTGTTCAAAATGCTCGAGACTGTTGATAAGGAAGTGGAGGAGGTAGAGAAGCCAGTAGATGATGATAGTGACGATGATGATCGTATGGATAATTTCAATGATGAGGAAGACTACTCAATGGAAAGCGGCAATGATAATGATAGAGATGCAGATTTTCAATTAAATAGCAGTGATGATGATATCCCATTGTCCCAGAGGACCAGACCAGCTCAAACCCGTAAGGCTAAGAAGGTGACCAAACAGCAGCACAAGAAAAAGAAGCAGCACCAGCAAACTAAAAAGCCCAAAAAGGACGCTGACGAGGATGAGGATGAACTAAGCAGTTCATCATTTGACTCCGATGAGGATGAGGACGGCGACAGTGATTCCAAATCGAAGGGCAAGCGCAAAAGAATACCAGCAGATGAACGTCATTTACATCGCCTTATCGATTGCCACATTTGCCATCAGAAGTTCAAGAAGGCCATTCGCTATGAGGAGCACATGAAGCACCACAATGATCTCTTACCTTTCCAGTGCACTGTGGAGTCATGTCGCAAGGGATTCACCACAGCCAATGGTCTGAGAGTTCATATAGAGCATGCCCACACGGAGACTTCTGAAATGCATCCCTGCACCGTTGAAGGATGTAATAAAAGCTTTGCCCGCCCCGTCTTGCTAAATTTCCACATGAAACGTGTCCACAAGATCAATACTCCACAGCGGGACTTCCCTTGCACCGAATGCGAGAAGGTATTCCGTTGTCCAACCGCACTCAAGAAGCACATGTACAAGCACACGGGCGAGGAGCTGCCATTTGCCTGTGAAATCTGTGGCAAACGATTCCCCATCAATAGCGTGCTACGCGATCACTTGCTCCGCCATGCTGGAATCAAGAACCACGTCTGCCCCTATTGTGGTGTTGGCAAGACCACTCGGCAAGAGTGGAATAAACACATCTTGACCCACACCAAGGAGAAAAAATATGCTTGCCGGCAATGCGAACATACATCGCACAACAAACAGGCTCTGGCCAATCATGTGAAAGTGGTGCACGAGAAGCGCAAGGATTTCGCATGTCAGTATTGTGGCAAAACCTTTGGCAAATCCCATGCCTGCAAGATTCATGAGCGTAGTCACACGGGTGAAAAGACATGCGAGTGTAAGATCTGTGGGAAAGTATTCCTATTCGAGAAGGGTCTAACAAAGCATTTGAAGACGCACGAGAAACGTGATTTGCCACGAACGCAATCGAATCCACTCAACATGCCCGATCAAGCGGAAGCCTCCACCTCTGCCGATGCCACTGCAACATCAAATTTCTCAGCTGCTGCTCCGACCACTTCTCAGTCTGTGCCCAAACACAAATCCAACAATTCGGGACGCGTTGAGCGTGTGGATATATCTCAATTGGCGGGCACTGTGGTAAATCCTATACCTTCAGTGAATCTCCCATCATGGTCGCCTCAGGTCAGTTTCACCAAGAAGGAGGGCCAACACATTTGTCCGGATTGCGGCAAGGGTTTCAATCATGTCAGCAATATGAAACTCCACTACAAAGTAGTTCATCAGAAGGTCAAGGATTTCTGTTGTCGCTTCTGTCCCAAACGTTTTGCCAAGAAACAATATTTGCGTCATCATGAGTACATCCACACCGGAGAGAAGCCCTATGAGTGCAAGATCTGTGGCAAACACTTCCGCCAGGAGCAAGTCCTTAAGACGCACATGAAAGTACACGATAAGCCACCAAAACCTCCAAGTAAATCTAGCAAGGAATCAGTTCCCAAATCTGATCATCAGCCAACGAAACGTCAGCAACCGAAGAACTTTGAGCAATATCAGGATCCGGCTGCCGAGCGAGCTGCCGCCACAGCTGAGCTGTTGGCCTTCCAGATCGAAGAGAATGAAGCTAAGCGCAAGGCTGAGATTGAATTGAAGAAAATCCAAGAGGCGGCCTTTGAGCAGCTAAATAAGCTGCAAAAGCAACAAAATACCTACGATGGCTTCTATGCTCAAAAGACCGCCGAGGAGGGCACCACTTTGGATTCTCTAAAGTTCGATCATGTGTAA
Protein Sequence
MNEGSALSSYSIHSVCRICLNHLQNGPVFDLFLIPGLAKKLCVCTSLSVEQQDGFPRNICCTCHSKLDDMHQFQKLCVDSVQKFQEMLANNAFQTSFDVLDPSVTAQDMPTQEDDDHINFDPLLNSKIEIIENEEDVFKMLETVDKEVEEVEKPVDDDSDDDDRMDNFNDEEDYSMESGNDNDRDADFQLNSSDDDIPLSQRTRPAQTRKAKKVTKQQHKKKKQHQQTKKPKKDADEDEDELSSSSFDSDEDEDGDSDSKSKGKRKRIPADERHLHRLIDCHICHQKFKKAIRYEEHMKHHNDLLPFQCTVESCRKGFTTANGLRVHIEHAHTETSEMHPCTVEGCNKSFARPVLLNFHMKRVHKINTPQRDFPCTECEKVFRCPTALKKHMYKHTGEELPFACEICGKRFPINSVLRDHLLRHAGIKNHVCPYCGVGKTTRQEWNKHILTHTKEKKYACRQCEHTSHNKQALANHVKVVHEKRKDFACQYCGKTFGKSHACKIHERSHTGEKTCECKICGKVFLFEKGLTKHLKTHEKRDLPRTQSNPLNMPDQAEASTSADATATSNFSAAAPTTSQSVPKHKSNNSGRVERVDISQLAGTVVNPIPSVNLPSWSPQVSFTKKEGQHICPDCGKGFNHVSNMKLHYKVVHQKVKDFCCRFCPKRFAKKQYLRHHEYIHTGEKPYECKICGKHFRQEQVLKTHMKVHDKPPKPPSKSSKESVPKSDHQPTKRQQPKNFEQYQDPAAERAAATAELLAFQIEENEAKRKAEIELKKIQEAAFEQLNKLQKQQNTYDGFYAQKTAEEGTTLDSLKFDHV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00571368;
90% Identity
iTF_00523894;
80% Identity
-