Basic Information

Insect: Drosophila sucinea
Gene Symbol: su(Hw)
Assembly: GCA_018150745.1
Location: JAECWP010000114.1:8442952-8446090[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.00062 0.046 14.2 2.2 1 20 238 257 238 259 0.94

2 12 2.6e-06 0.00019 21.7 0.4 3 23 310 331 308 331 0.93

3 12 0.41 30 5.3 0.1 1 23 337 359 337 359 0.93

4 12 5e-07 3.7e-05 23.9 2.4 1 21 366 386 366 387 0.95

5 12 5.7e-06 0.00042 20.6 1.0 2 23 399 420 398 420 0.96

6 12 9.7e-05 0.0072 16.7 5.3 1 23 431 453 431 453 0.99

7 12 7.5e-05 0.0056 17.1 0.9 1 23 459 481 459 481 0.97

8 12 8.7e-06 0.00064 20.0 0.7 1 23 487 509 487 509 0.98

9 12 1.9e-06 0.00014 22.1 2.2 1 23 515 537 515 537 0.97

10 12 1.5e-05 0.0011 19.3 0.5 1 23 541 563 541 563 0.97

11 12 6.9e-05 0.0051 17.2 0.2 1 21 571 591 571 595 0.92

12 12 7.1e-06 0.00053 20.3 0.4 3 23 615 636 613 636 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.00062	0.046	14.2	2.2	1	20	238	257	238	259	0.94
2	12	2.6e-06	0.00019	21.7	0.4	3	23	310	331	308	331	0.93
3	12	0.41	30	5.3	0.1	1	23	337	359	337	359	0.93
4	12	5e-07	3.7e-05	23.9	2.4	1	21	366	386	366	387	0.95
5	12	5.7e-06	0.00042	20.6	1.0	2	23	399	420	398	420	0.96
6	12	9.7e-05	0.0072	16.7	5.3	1	23	431	453	431	453	0.99
7	12	7.5e-05	0.0056	17.1	0.9	1	23	459	481	459	481	0.97
8	12	8.7e-06	0.00064	20.0	0.7	1	23	487	509	487	509	0.98
9	12	1.9e-06	0.00014	22.1	2.2	1	23	515	537	515	537	0.97
10	12	1.5e-05	0.0011	19.3	0.5	1	23	541	563	541	563	0.97
11	12	6.9e-05	0.0051	17.2	0.2	1	21	571	591	571	595	0.92
12	12	7.1e-06	0.00053	20.3	0.4	3	23	615	636	613	636	0.97

Sequence Information

Coding Sequence: ATGAGTGCCTCCAAGGAGGGTAAAAGGTGGGAAAACGAGACTGTAGTGAAAATCGTGGCCCTCAATCAAGTTACGTCGCCCAAGGACAAAGACAAACGTCCGGCCACACGTATGAAATTGCTGAATGATGTAACAGGATCGGAAACTTCGACAAGTGATAAGGCGGAAAAGCGTGCAGGAGGAGGTGCGCGTATTAAAATACTGAACGATGATGCTAACACGCCTACCAGGGCGGAGAAACGGTTAAGCGGTGGCAGCAACGGAGGCAGTAAGAAGACAGTCAGTCCAGCTGCTGCTCCTGGTGCCTCGGCTGTTAAGATTCTAAACGACAAGCGTTTCCCCTCACCAGTCACGTCCATGGAAACGGTGAAGATTAAGGCCAATCCTAGTAGGAAAAAGAAAACGGATCACTATGTTCTCGAATCGATTAAAAATGAGAACAGTAAAGCTCCGCCGGATGTGACGGCCAAAGTAGTTGTGCACAACGAAGATGAAGATGATGAGGACGATGATGGAGCCATCGCCTTTATCCTTGCTGAAGTCGATGATGAGGAGATGGATGTGGGGAACCACAATGGGACGCAAATTGTAGTCGGTGGCGTGACAGAAGACGATGGCGATGGGGAGGACGAGGAAGGCGATGAGAGCCAAGTGGTCACTGGTGGCCATAATACAACGGCCAATCAGAGTAACATCAAGGAAATTGTGGAGCATGTCTGCGGCAAATGCTACAAGACATTCCGTCGCGTCAAAAGTCTAAAGAAACATTTGGAATTCTGTCGCTATGACAGTGGCTACCATCTACGCAAGGCGGATATGTTAAAGAACATTGAAAAAATCGAAAAGGACGCTGTCGTTATGGAGAAAAAGGATATCTGTTTCTGTTGCAACGAGAGCTACGACACTTTCCATCTGGGTCATATCAACTGCCCGGATTGCCCAAAGTCCTTCAAGACGCAGACCAGCTATGAGCGTCATATTTTCATTACCCACTCTGAATTCAATACGTTCCCCTGCTCCATTTGCAATGCAAATTTGCGCAGCGGAGCCCTTTTGAAGTTGCACGAAGAGCAGCATAAGAATCGCGGCAAGCCCTATGCGTGCAAAATCTGTGGCAAGGACTTCACAAGATCGTATCATCTGAAGCGCCATCAAAAATACTCTTCATGCTCGGCCAATGAGACCGACACCATGAGCTGCAAGGTGTGCGATCGTGTGTTCTATCGCCTTGACAATCTACGCTCCCATCTAAAGCAGCATCTGGGCACCCAAGTTGTTAAGAAACCCGAATATATGTGTCATGTGTGCAAGAATTGCTTCTACAGCTTATCCACACTCAACATTCATATACGAACCCATACGGGTGAGAAACCCTTTGATTGTGATTTGTGTGACAAGAAATTCTCTGCCTTGGTGGCCCTCAAGAAGCATCGACGCTATCACACAGGGGAGAAACCCTACAGCTGCACAGTGTGCAATCAATCCTTTGCCGTGAAAGAAGTCCTCAATCGTCACATGAAACGTCACACAGGCGAGCGTCCGCACAAGTGCAATGAGTGCGGCAAAAGCTTCATTCAGGCCACACAATTGCGCACCCATTCCAAGGTTCATTTGCGTCCATATGCATGTGATTTATGCGACGAGAAGTTCAAAACGGAGAAGCAATTGGAGCGCCACGTCAAGGAGCATACACGCCAAAGGCGACCATCTTTTGCCTGTTCTGAATGTAAGCGAAACTTTCGTACTGCTGATTTGCTCAAAGAGCACATGGATGCTGGTGATCATACACCTAAGCCACAACGCGCCAAGCGCACTAGCACCAAAATGATTGGGCGTACCGATTGCGCCATTTGTGACAAGAACTTTGATAGCACCGATACCTTGCGCAAGCATATACGCACCGTACACGAGTGTGATCCCGATGATATCTTTGGAGTAGATCCACCCTCGGCGAAGCAGAGGAAAAGAGGTGATAAATCTACTGAGCAGGTGGAGAATGATGCAGCAGATGAGGAGGAATCGGCAGATGGATTGGCTCTTAATCCCTCGCCCGGTTCGCTTATTTCCAGTCAAACGGAAGGCAATGGAGTGGTGGTGCGTGAGTTCCTCTTGGATGAGGGCGATGGCGCCGCTCAGACAATTATGCTCGAGAATGAGACTTATACCATACTCCCGCTTGAGGGAGAAATTGAAGCTGGTGAGGAACCACCATTGCCAGAGGGCAAACAACCGAAAACAGAAATAAAGAAGAAGTCAGCCCAAGTGTCACCTGTCGTTAAGAAGGAACAACGCAAGTCCTTGGCTGCCAGTCTGGCGGAGGCCATTGCCGACAATGTGGATGAAGATGACTTCACCGGCGAAGTGCTCACCGAAGAAGATGTGAAGCTAAAGGAGAATGTGGCCAAATTGATTGATATGCTGGTGGATCCACCAATACTTAAGAAATACGGCTGGCCAAACACCTCCGAGGAGACGGTGCTCTGCAAGGTGATCGAGAATTGTGGTCACGATTTGACCAAAGGGGGCGATAACTATGCTGAGATGGAGTATGGTTCACGTATGCGTGAATATTGCAAACTTCTCTTCACTGTGGTCATCCACAATGATTCCATTAAATCATTGCTCAACAATTTCCCCATTGACGATGTGATTGAATACGTTCTGGGTGACGAGGATCAGGAAGATAGCGACAGCAAAGACAAAGCTCATGATGGTGATGAAGATGTTGATGACATGGACAATGATGATGATATGGATGATATTGAAGATGGCGATAAGAAGTCAATCAAAAAGGCGGAGGCCATCGAAGAGAAAGACTAG
Protein Sequence: MSASKEGKRWENETVVKIVALNQVTSPKDKDKRPATRMKLLNDVTGSETSTSDKAEKRAGGGARIKILNDDANTPTRAEKRLSGGSNGGSKKTVSPAAAPGASAVKILNDKRFPSPVTSMETVKIKANPSRKKKTDHYVLESIKNENSKAPPDVTAKVVVHNEDEDDEDDDGAIAFILAEVDDEEMDVGNHNGTQIVVGGVTEDDGDGEDEEGDESQVVTGGHNTTANQSNIKEIVEHVCGKCYKTFRRVKSLKKHLEFCRYDSGYHLRKADMLKNIEKIEKDAVVMEKKDICFCCNESYDTFHLGHINCPDCPKSFKTQTSYERHIFITHSEFNTFPCSICNANLRSGALLKLHEEQHKNRGKPYACKICGKDFTRSYHLKRHQKYSSCSANETDTMSCKVCDRVFYRLDNLRSHLKQHLGTQVVKKPEYMCHVCKNCFYSLSTLNIHIRTHTGEKPFDCDLCDKKFSALVALKKHRRYHTGEKPYSCTVCNQSFAVKEVLNRHMKRHTGERPHKCNECGKSFIQATQLRTHSKVHLRPYACDLCDEKFKTEKQLERHVKEHTRQRRPSFACSECKRNFRTADLLKEHMDAGDHTPKPQRAKRTSTKMIGRTDCAICDKNFDSTDTLRKHIRTVHECDPDDIFGVDPPSAKQRKRGDKSTEQVENDAADEEESADGLALNPSPGSLISSQTEGNGVVVREFLLDEGDGAAQTIMLENETYTILPLEGEIEAGEEPPLPEGKQPKTEIKKKSAQVSPVVKKEQRKSLAASLAEAIADNVDEDDFTGEVLTEEDVKLKENVAKLIDMLVDPPILKKYGWPNTSEETVLCKVIENCGHDLTKGGDNYAEMEYGSRMREYCKLLFTVVIHNDSIKSLLNNFPIDDVIEYVLGDEDQEDSDSKDKAHDGDEDVDDMDNDDDMDDIEDGDKKSIKKAEAIEEKD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00600464;
90% Identity: iTF_00555241;
80% Identity: -