Basic Information

Insect: Drosophila sucinea
Gene Symbol: -
Assembly: GCA_018150745.1
Location: JAECWP010000114.1:492993-497591[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 24 0.0021 0.15 12.6 1.0 1 23 214 236 214 236 0.96

2 24 0.00042 0.031 14.7 1.2 1 23 242 264 242 264 0.98

3 24 0.0031 0.23 12.0 0.4 2 23 296 317 295 317 0.96

4 24 0.012 0.92 10.1 2.1 1 22 391 412 391 414 0.89

5 24 7.1 5.2e+02 1.4 0.7 2 21 424 443 423 444 0.90

6 24 3 2.2e+02 2.6 1.6 3 23 485 505 484 505 0.96

7 24 0.0065 0.48 11.0 1.4 1 23 585 608 585 608 0.96

8 24 0.11 8.5 7.1 1.6 1 22 617 638 617 638 0.95

9 24 0.35 26 5.6 3.9 1 23 647 670 647 670 0.97

10 24 4.4e-05 0.0032 17.8 0.5 2 23 693 714 692 714 0.97

11 24 2.5e-05 0.0019 18.6 5.7 1 23 722 744 722 744 0.98

12 24 0.059 4.4 8.0 0.8 1 23 892 915 892 915 0.93

13 24 0.0012 0.086 13.4 0.8 2 22 924 944 924 944 0.94

14 24 0.46 34 5.2 5.5 1 23 953 976 953 976 0.95

15 24 7.3e-06 0.00054 20.3 4.2 2 23 991 1012 990 1012 0.97

16 24 0.00013 0.0096 16.4 0.9 1 23 1018 1040 1018 1040 0.98

17 24 0.0015 0.11 13.0 0.3 2 21 1067 1086 1066 1087 0.94

18 24 0.0082 0.61 10.7 4.8 1 23 1133 1156 1133 1156 0.96

19 24 6.7e-05 0.005 17.2 1.8 1 23 1250 1273 1250 1273 0.98

20 24 5.4e-06 0.0004 20.7 0.2 2 23 1309 1330 1308 1330 0.95

21 24 0.00075 0.055 14.0 3.0 1 23 1336 1358 1336 1358 0.99

22 24 2.1e-06 0.00016 22.0 2.0 1 23 1364 1386 1364 1386 0.97

23 24 1.9e-07 1.4e-05 25.3 2.4 1 23 1392 1414 1392 1414 0.99

24 24 0.0005 0.037 14.5 0.2 1 22 1420 1441 1420 1444 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	24	0.0021	0.15	12.6	1.0	1	23	214	236	214	236	0.96
2	24	0.00042	0.031	14.7	1.2	1	23	242	264	242	264	0.98
3	24	0.0031	0.23	12.0	0.4	2	23	296	317	295	317	0.96
4	24	0.012	0.92	10.1	2.1	1	22	391	412	391	414	0.89
5	24	7.1	5.2e+02	1.4	0.7	2	21	424	443	423	444	0.90
6	24	3	2.2e+02	2.6	1.6	3	23	485	505	484	505	0.96
7	24	0.0065	0.48	11.0	1.4	1	23	585	608	585	608	0.96
8	24	0.11	8.5	7.1	1.6	1	22	617	638	617	638	0.95
9	24	0.35	26	5.6	3.9	1	23	647	670	647	670	0.97
10	24	4.4e-05	0.0032	17.8	0.5	2	23	693	714	692	714	0.97
11	24	2.5e-05	0.0019	18.6	5.7	1	23	722	744	722	744	0.98
12	24	0.059	4.4	8.0	0.8	1	23	892	915	892	915	0.93
13	24	0.0012	0.086	13.4	0.8	2	22	924	944	924	944	0.94
14	24	0.46	34	5.2	5.5	1	23	953	976	953	976	0.95
15	24	7.3e-06	0.00054	20.3	4.2	2	23	991	1012	990	1012	0.97
16	24	0.00013	0.0096	16.4	0.9	1	23	1018	1040	1018	1040	0.98
17	24	0.0015	0.11	13.0	0.3	2	21	1067	1086	1066	1087	0.94
18	24	0.0082	0.61	10.7	4.8	1	23	1133	1156	1133	1156	0.96
19	24	6.7e-05	0.005	17.2	1.8	1	23	1250	1273	1250	1273	0.98
20	24	5.4e-06	0.0004	20.7	0.2	2	23	1309	1330	1308	1330	0.95
21	24	0.00075	0.055	14.0	3.0	1	23	1336	1358	1336	1358	0.99
22	24	2.1e-06	0.00016	22.0	2.0	1	23	1364	1386	1364	1386	0.97
23	24	1.9e-07	1.4e-05	25.3	2.4	1	23	1392	1414	1392	1414	0.99
24	24	0.0005	0.037	14.5	0.2	1	22	1420	1441	1420	1444	0.91

Sequence Information

Coding Sequence: ATGCTGCCACCGGACATTTGTCGAACGTGTGCCACGCAGCATAATAATTTATTACCGCTGGCCTCCTGCTCGGAAAAGCTACAAGAATTAACACAAATTCCTCTATTGGAGCAGGGCGATGAAAATTTACCACAGCATTTGTGTGCCGATTGCCTGGCCAAATTAGAGAGTGCTTATGCCTTCGTGGAGCAAGCGCGTAAGGTGAATAGGGAGCTGCTAATGAAGTTGAGGCAGTGCCTCCTCGAGGAGACACCCATTGACATACCAATCCCCAATGCCATGCAACATCAGATCAAGATGGAAATGGACGATGAAGATGCTGGTCAGCAAGAACTAGATGAAGAAGAGGCGGCAGCCACAAGATTGGAACTCAAATGGCAAGCAGACAGTGAAGCGGAAAGTGAAGCCGAGGAGGAGGAAGCAGCTGATGGTAATGAAGGCGAATACAAACCGTACCAGCTTAGGCGGAGCCTACGCAAGATCAAGCAGCAATCGGATAGCGAACAGGAAGATCAGCAGCGCGAGGAGGACAAAATAAATCTCAACCCAGAGTTAAATGACCCAGAGCCGCCTCCCAAGCGTCGCCGTGGTCGCCCTCCTCGCCTGGCCAAATCCTTAGCTCTCAATTCCGACGGTCGACACGCATGTGCTGAGTGTGGCAAAACGTTCTCCTGGTATCGGGATATGCAACGTCATGCTCGCAGCCATTTCGAAGACGCCGCCTACAACTGTCCACAATGTGGCAAAGGATTCCTGCGCAAGGATAAATACATGTCTCACCTAAAGTCGCATGAGAGACGACAGGCCAAACGAGAAGTTATCGAATTGGCTAAAGAATGGAAATTCGCTGAGCGTCTGTATAGCTCGGAGCAACTGAAGCATATCGAATGCAAATTATGTTTCGTAGAATTTTCAAAGTTAAAGGACTTAAGATCCCACATGGATATCCATTCGTCCAAAGAAACTCTAGGCCAATTGAAATTGGATCAAGAAGTGGTTAAAGAACACTTTGGAGATGATAACATTGATATAGAAAAGATCAAAGATTTAATAACTAAAGATATAAGTGAAGGACAGTTGGAAAAGTTCTGTGCTGTGGTCAACGCGAATGGCTATGAATTAAGTTTAAGTGATTCCGATGAAGATTTGCCTGACGACATCGAACCCAAATACCATTGTGTGTCCTGCAATGTGCCCTTTAAGCGCAAGCATCTACTCATTCGTCACACAGTGGAAGAGCATTCCCAGGAGCAGAACCAGCCACAATTACGCTGTAATCTCTGCCAGATCGGTTTCGTCTGCCTCAATTTGTATGAGCAACATCAACGCTCTCAATGTTATGGTAAATTTAAGCGATACGGTTGCCGAAAATGCCCTGGCAAATTTATGTGGTTGGAGAACTTGGAGAAACATGAATGTGTCCAAAGCAGAGAGGAGGATAAGCAAATTCTTTGCTGCCTCTGCGATTGCCAATTGCCCAGTTTAGTTCAGTTGAGAGCTCATTTGGTCAGTCATAGAGATGGCCTAACCGGCATTGATCCTCTATATCAAGCAACATTTTTCCGTTGCTATTACCCAAAGGGTTTAGCGTGCAGCCAGTCCGAACTAAGCTCACGCATAATTGGTGATTTTGATGCTCAAGATTATGGTCGCTATTATAACGCCAGCCTTAGCTCTGGCCAAGAATTGGATTTCTATGACTCCGATTCGGATGAGAGTGATGGTCCTGTAGAATCTCAAGAAAAGCCCTTGCACACATGTTCCCTATGCGGTGAATCAATGAAACGTTTAACCAATCTTCTGGAACATCAACAAAACTCTCATGGTCAGGAGATGGCAACGTTTTCGTTTTCTTGTAAAGATTGCTCGGAGCGGTTCGTCTGTGAAGCTCTTCTGCAGCAGCATCGGCGTCGTTCATGTGGCAAGGCACATGCCAAATTCCATTGTCAGTTGTGTCAGATGCATTTCGTTTGGCAAACCAATTATGAGCAGCATTTGCGGGTAAACCATCCATCAGAGAAGGATTTGGATCAGAATATCAAACGGAAACCTGCCGCTGCCGCTGTTGCCAGGCTGAAATGTAATGAGTGTGACAAGGTTTTCATTTGGCCAAAGGATCTTAATCGTCACAAACGCATGCATCAGCCTAGGACAGCATCTCAGTTTGAATGCACGCACTGTGAACGTAAGTTCCATCGCAAAGATGGTCTCAAGTCCCACATGCGAGTGCATAGCGAGGAGCAGCAGCAGCTGGAAAAGATTGATAATGATGAGCATGAGGAGAAACCGCAAGCAATCCAGATTTTAAGCGAACTAAGTCGGCCTCATGGATGCAAGCAAATCCAATGCATGATTTGTCATTCGCAACACTCCAAAATAGCCGATTTGCGATGTCATCTAATGTCCCATCAGTATGTCATCAGTTTGCCACCCGAGAGAGAGAAGGATATAGTTGGAGTTTCCAAATCCTTGTATCCCGAATTGACTGTGGCCCTGTCCAGAGATAATTTAATATCACGTATTATGAATGACATCGGCAAGGGTGTGGAACTAGACAGATTCATATCCATTACCAATGAATCGGGCTTTGAACTTAGTTTGGATAGCAGCGAAACGGATTCAGATACGGAGGAGGAGACGGATGCGAATGATGGCCGTCTTAAGACGAATCGCTATGCTTGCTCCATATGTCAAGTGGAGGTGAAGAGGAAACATCAATTGTATGGCCATCAATTGGATCAACATCCTTGTGCAGAGGCAGCCACAAATGTGTGCCCGCATTGTCAGACGAGATTTGTGAGTGAGCAACTACTCGAACATCATTTGAGATCACAGTGCCGAAATAATCAGAAGAGGCATCAATGCAGGAAGTGCACCTGGCGCTTCCGTTGGCGGGACAACCTTAAGCTCCATAATAATGTATGCCATCAAGCAGATGATTCCATTTTGGGAGCAGATGGTGGAGAATTGCGCTGCAAGGAATGCCATCGAAGCTTCAAAATGCAAAAGGATCTAACCCGTCACATGCTGATGCACTCGGATACGAGTATCTATCGTTGTCGTTGGTGTGCCCGCCGTTTCTATCGGCAGGCCAATCTTCTACAACATATCGAGCGTCACGGCATCAGCGCCGATCAATTGCCTTATGCTGAAGCTCTGCTTAATTCGTATAATCATCCACATGGTCAGAAGGTCATTCAATGTAAAGTGTGCAATATAAACTTTAACTCAATCACTGAGCTACGCCGTCATTTAAAGAGCTCTCCGAATGATTCGCACCATGAACTCACTTCCATGCAAAACTATTCCATTACCAATCAATTGGGCTATGAGCTTCATTTGGACGACTCTGAGACAGATGAGGAGGACATCAAATCGGGAGGTACTAATGAAATTTACACCTGCAGCATGTGTCACCTGCGTTGTGCGCGCAAATATGAACTGTATCAGCATCAACAGGCCATGCATAGGTTGGAGCGTATTCCCGATGGCTGCGATCAGTGCATCTTTAAGAGCGTCTCCAATGACATTATCGAGCATCATAAGCGTAATCAGTGTAACAATCAGGAAAAGCCCTTCAAATGCATTAAATGTGGCTTCAAGTTCATGTGGGAATCCAATATGTTAATACATGCGGATCTCCAGCATAGCAAAAACGAAGAGGAAGAGCAAGTGCAGGAACAACAAACAGTGGAGCAACCGGATTCATCTTTAAATTCCTCGAATTCCAAACAAATGCAACAAATCTTCCAGTGTGCTCTCTGCCCCAGGAAATACAATCGCAAAGATCGTCTCACGGCGCATATGAAAAAATTCCACAATCCAGGTGGATCCACCACAGCATCTCCTGCTCCATCAAAGAAATCTCCATCATCTTCAGCAGCAGCATCATCCATAGCTTCGGTTAAGCAACCGAAACTATTTTTATGCGCCTTCTGTGGCAAGGCAGTCAGTTCCTCCTCCAATCTCATTATCCACATGCGTCGGCACACAGGTGAAAAGCCCTTCAAGTGTGATTTTTGTGAGATGGCTTTCCCCCGATCGTCGGATCTCCAGTGTCATCGGCGTACACATACGGGCGAGCGTCCCCATGTCTGCACCGTGTGTCAAAAAGGTTTTGCCAGATCCTATAAGCTGCAGCAACATATGCGCATTCACAATGGAGAACGACCGTACAAGTGCACCTATTGCGAGAAGAGTTTCACCCAATCCAACGATTTGACTCTCCATATACGTCGCCACACCGGCGAGCGGCCCTATCAATGTGGCATCTGTGGTGAGCGTTTCATTCAGGGCACTGCCTTGAAGAATCATCGCCAGCAGCAGGGACACCATGAACCAGGCACTCAGGGTGGAATGCCAGGAGAGGCACCCATAAGGCGTACAGTTCTTCAGCAATTTTCAGGCGAATGA
Protein Sequence: MLPPDICRTCATQHNNLLPLASCSEKLQELTQIPLLEQGDENLPQHLCADCLAKLESAYAFVEQARKVNRELLMKLRQCLLEETPIDIPIPNAMQHQIKMEMDDEDAGQQELDEEEAAATRLELKWQADSEAESEAEEEEAADGNEGEYKPYQLRRSLRKIKQQSDSEQEDQQREEDKINLNPELNDPEPPPKRRRGRPPRLAKSLALNSDGRHACAECGKTFSWYRDMQRHARSHFEDAAYNCPQCGKGFLRKDKYMSHLKSHERRQAKREVIELAKEWKFAERLYSSEQLKHIECKLCFVEFSKLKDLRSHMDIHSSKETLGQLKLDQEVVKEHFGDDNIDIEKIKDLITKDISEGQLEKFCAVVNANGYELSLSDSDEDLPDDIEPKYHCVSCNVPFKRKHLLIRHTVEEHSQEQNQPQLRCNLCQIGFVCLNLYEQHQRSQCYGKFKRYGCRKCPGKFMWLENLEKHECVQSREEDKQILCCLCDCQLPSLVQLRAHLVSHRDGLTGIDPLYQATFFRCYYPKGLACSQSELSSRIIGDFDAQDYGRYYNASLSSGQELDFYDSDSDESDGPVESQEKPLHTCSLCGESMKRLTNLLEHQQNSHGQEMATFSFSCKDCSERFVCEALLQQHRRRSCGKAHAKFHCQLCQMHFVWQTNYEQHLRVNHPSEKDLDQNIKRKPAAAAVARLKCNECDKVFIWPKDLNRHKRMHQPRTASQFECTHCERKFHRKDGLKSHMRVHSEEQQQLEKIDNDEHEEKPQAIQILSELSRPHGCKQIQCMICHSQHSKIADLRCHLMSHQYVISLPPEREKDIVGVSKSLYPELTVALSRDNLISRIMNDIGKGVELDRFISITNESGFELSLDSSETDSDTEEETDANDGRLKTNRYACSICQVEVKRKHQLYGHQLDQHPCAEAATNVCPHCQTRFVSEQLLEHHLRSQCRNNQKRHQCRKCTWRFRWRDNLKLHNNVCHQADDSILGADGGELRCKECHRSFKMQKDLTRHMLMHSDTSIYRCRWCARRFYRQANLLQHIERHGISADQLPYAEALLNSYNHPHGQKVIQCKVCNINFNSITELRRHLKSSPNDSHHELTSMQNYSITNQLGYELHLDDSETDEEDIKSGGTNEIYTCSMCHLRCARKYELYQHQQAMHRLERIPDGCDQCIFKSVSNDIIEHHKRNQCNNQEKPFKCIKCGFKFMWESNMLIHADLQHSKNEEEEQVQEQQTVEQPDSSLNSSNSKQMQQIFQCALCPRKYNRKDRLTAHMKKFHNPGGSTTASPAPSKKSPSSSAAASSIASVKQPKLFLCAFCGKAVSSSSNLIIHMRRHTGEKPFKCDFCEMAFPRSSDLQCHRRTHTGERPHVCTVCQKGFARSYKLQQHMRIHNGERPYKCTYCEKSFTQSNDLTLHIRRHTGERPYQCGICGERFIQGTALKNHRQQQGHHEPGTQGGMPGEAPIRRTVLQQFSGE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00612227;
90% Identity: iTF_00555240;
80% Identity: -