Basic Information

Insect: Drosophila subsilvestris
Gene Symbol: -
Assembly: GCA_035043285.1
Location: JAWNNB010001922.1:4308741-4310905[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.013 0.94 10.2 1.7 6 23 302 319 302 319 0.98

2 9 3.2e-05 0.0023 18.4 3.4 1 23 325 348 325 348 0.93

3 9 3.4e-05 0.0024 18.3 0.8 1 23 356 378 356 378 0.97

4 9 0.00087 0.063 13.9 0.1 2 23 384 406 383 406 0.95

5 9 0.14 10 6.9 0.1 2 23 412 433 411 433 0.95

6 9 8.3 6e+02 1.4 7.0 2 23 442 463 441 463 0.91

7 9 0.00022 0.016 15.7 0.3 2 23 472 494 472 494 0.96

8 9 1.1e-05 0.00079 19.9 0.8 1 23 500 522 500 522 0.97

9 9 7.8e-05 0.0056 17.2 5.5 1 23 528 551 528 551 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.013	0.94	10.2	1.7	6	23	302	319	302	319	0.98
2	9	3.2e-05	0.0023	18.4	3.4	1	23	325	348	325	348	0.93
3	9	3.4e-05	0.0024	18.3	0.8	1	23	356	378	356	378	0.97
4	9	0.00087	0.063	13.9	0.1	2	23	384	406	383	406	0.95
5	9	0.14	10	6.9	0.1	2	23	412	433	411	433	0.95
6	9	8.3	6e+02	1.4	7.0	2	23	442	463	441	463	0.91
7	9	0.00022	0.016	15.7	0.3	2	23	472	494	472	494	0.96
8	9	1.1e-05	0.00079	19.9	0.8	1	23	500	522	500	522	0.97
9	9	7.8e-05	0.0056	17.2	5.5	1	23	528	551	528	551	0.98

Sequence Information

Coding Sequence: ATGATTTGCCGTTTGTGCCTAAACAGCGTCAGCGACACGGACACCATCCAGATCTTCGAGAGCATCGGCCTCACCCTGAACGTGGCCACTGTGCTGTCGAAGTACTTTTGGTTCGAGCCAAAAAACGATGATCCCATATCGACGGTGATTTGCTTGGACTGCTGGAACCAAGTCAGCCAATTCCACGAGTTCTTTGTGGCCGTGGAGAAGGCGCACCGGCTGCTCACCGAACGCTTCTCCCTGAATGTGGGGGAAAAGGCGAACAGCGGACAGCCAGAGGGTGAGGAGGAGCCAAACCTGCTACCCGAGGAAGCAGAGGAGGTGCACCAGTTGCCTGATGAGAAGGAAGCGCTCAGCCAGTTGCTTGAGGAGTCGCAGAAGTCACATCAGTTGTCTGATGGGGCGGAGGAGCTGATCTTCCAACAGGAATTGGACGTGGGCCATCAGGACTGCGACAGCGATGCCTCCTTCAGCAATGAGCAGTTCCTCAACCAGGTACTGTGTCAGCAGGATACCACTGACGACCAGCAGGCATCTCTTGCCGAGAAGCAAGAGGAAGTGGATCTCAAGAATGTGCCACTGATTGCTGTCGAAGAACGTCGGGAGACGCGCTCAACAGCCAGGAATCAAATCCCATCAAGCACAGTCACAGACAGCGAACCGAAGCCTGTGAATCCTTCCGCTGCCGTCGCCAAGCGACGAATGCGAACTCGCAAGTCCGAGGAGCATTCGATGAAAACCAAACGGTACGTGGACTATAAAAAGTCCATGCTGGATATCGACCAGAAGATCGCTGGCCATATGCGTCTCACCTGCGACATCTGCCACCAGGGGCACGCGACCTTCCTGCTGCTCTGCAAGCACATGCTGCAGGTGCACCACCGCAAGGGCTATGCCATCTGCTGCCACAAGAAGTTCTACAAGCGATCGGCACTCACGGACCACATTGATCGACACATAGATCCCGAGAAGTTCAAgtGCACTGAGTGCGACAAAACTTTTGCGGACAAGCAGTGCCTGCGGAATCACGAGTTGCTGAAGCACCAGCCGGACGATGTGAAGGTCTTCATGTGTGAGCAGTGTCCCAAGCGCTACACGAAGCAGTATTTGCTGGAACAGCATCGCATCATCCACAAGGAGCGCACCATACCGTGCGGCATCTGCGAAAGAAGGTTTCCCAATGACTCCCTGCTCAGTACCCACGTGAAAATGGTGCACAGCAACTATGGCACAATGTGTGACATCTGCGCTCAGGTGATACGCGGACGAGCGGCCTTTAAGCGGCATCAGCTGGAGCACTCGGGTGTCTTAGAGCCGAAGGTACAGTGCGACATCTGTGGATCGTGGCACAAGAACAGGCATAGCCTGAAGAAGCATGTGCGTCGACACAAGGGCTCCTCGGAAGAGGTGCGCACGTGCAAGGTGTGCGGCAAGGTGTCGCCCAATCGAAGCGCCATGCTGAGCCATCAGCGATATGTGCATTTGGCGGATCGCAAGCACGAGTGCAGTGTGTGCAACAAGGCATTCAAGAAGGCCATCACCCTCAAGGAGCACATGGCCATGCATACGGGCGAGGTCCTCTACAAGTGTCCACACTGCCCCAAGACATTCAATTCGAATGCCAACAAGCACACCCATCGCAAGAAGGCTCATCCCAAGGAGTTCGAGGAGGCGCGCAAGGCACGCACCGAGAGCCGAATGGCCACCGCCGAGGATGGGCCTGAGACCCACCACATTATCACAATCTCAACGGAAGGCGACGAGGGCGAAAGCGAAACACACAACATCCTGCTGACCGCCACCGAGGAGGATCTTAAGGCCGAGGGCATTGAGTTCACCCTGTGCCTTAGTCCGCAAGCGGCAGATTGA
Protein Sequence: MICRLCLNSVSDTDTIQIFESIGLTLNVATVLSKYFWFEPKNDDPISTVICLDCWNQVSQFHEFFVAVEKAHRLLTERFSLNVGEKANSGQPEGEEEPNLLPEEAEEVHQLPDEKEALSQLLEESQKSHQLSDGAEELIFQQELDVGHQDCDSDASFSNEQFLNQVLCQQDTTDDQQASLAEKQEEVDLKNVPLIAVEERRETRSTARNQIPSSTVTDSEPKPVNPSAAVAKRRMRTRKSEEHSMKTKRYVDYKKSMLDIDQKIAGHMRLTCDICHQGHATFLLLCKHMLQVHHRKGYAICCHKKFYKRSALTDHIDRHIDPEKFKCTECDKTFADKQCLRNHELLKHQPDDVKVFMCEQCPKRYTKQYLLEQHRIIHKERTIPCGICERRFPNDSLLSTHVKMVHSNYGTMCDICAQVIRGRAAFKRHQLEHSGVLEPKVQCDICGSWHKNRHSLKKHVRRHKGSSEEVRTCKVCGKVSPNRSAMLSHQRYVHLADRKHECSVCNKAFKKAITLKEHMAMHTGEVLYKCPHCPKTFNSNANKHTHRKKAHPKEFEEARKARTESRMATAEDGPETHHIITISTEGDEGESETHNILLTATEEDLKAEGIEFTLCLSPQAAD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00564158;
90% Identity: iTF_00487505;
80% Identity: -