Basic Information

Insect: Drosophila subsilvestris
Gene Symbol: -
Assembly: GCA_035043285.1
Location: JAWNNB010000133.1:5918734-5920584[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 6.4 4.6e+02 1.7 0.1 1 23 402 424 402 424 0.82

2 7 1.3e-05 0.00094 19.6 1.5 1 23 430 452 430 452 0.98

3 7 1.3e-06 9.7e-05 22.7 0.6 3 23 460 480 460 480 0.99

4 7 3.8e-06 0.00028 21.3 6.1 1 23 486 508 486 508 0.98

5 7 1.6e-05 0.0012 19.3 0.8 2 23 515 536 514 536 0.97

6 7 0.00037 0.027 15.0 5.9 2 23 543 564 542 564 0.96

7 7 5.5e-05 0.004 17.7 0.2 1 23 570 592 570 592 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	6.4	4.6e+02	1.7	0.1	1	23	402	424	402	424	0.82
2	7	1.3e-05	0.00094	19.6	1.5	1	23	430	452	430	452	0.98
3	7	1.3e-06	9.7e-05	22.7	0.6	3	23	460	480	460	480	0.99
4	7	3.8e-06	0.00028	21.3	6.1	1	23	486	508	486	508	0.98
5	7	1.6e-05	0.0012	19.3	0.8	2	23	515	536	514	536	0.97
6	7	0.00037	0.027	15.0	5.9	2	23	543	564	542	564	0.96
7	7	5.5e-05	0.004	17.7	0.2	1	23	570	592	570	592	0.98

Sequence Information

Coding Sequence: ATGCCGCCCTATCAGCGCTGCGGGGAGATTGTCTGGCTGGGTAAGCGGCAGACGACGGCTTTCGCCTTCCAGTGCATCTACTGCCGGGACGAGGAGCAGACCAGGACACTCAAAGAGTTCAAGTCGCATCTAGAATCGAAGCACGCGGATCTGTTTGAAGATCAGAAGACTGCAcagacagccacagcctcggACACGACGCTGCGTAGGAGTGGTGCCAGCAAAGAGCAGGCCTTCGAGCCAGAATTGGCCATTGGGAAAGTGGAAAGAGAAGCAGAACCGCCTGTTGATAATGCTCTACCCCTGCCCGATGCTacggctgctgcggctgctgctgacccGCTTTcagatgctgatgatgatgcttcTGAAGAGTGCTTTGAGTCAGAGACAATGTTGTACTGGCCCAGCCAGAGCGATGGCCAGAGCACCACCTCCCAGGAGTGCTACAATGAGGCAAGCTTAGCACTATGCCCAGGCGCAGGGACATGCACGGACACCACGTACTTCTGGCTGCAGGAGCACCCCATTATGCTGGCCTTCATCGggcagctggaggagcagcgccTGCTCTGGGACTTGGGCATGCTGGCCTACCGCAACTACAAGCATCGCAGCGAAGCCTGCACGACGATCGCCGAGCGGCTGAACTCGCAGTTTGGTCTGCAGTTGACGGGCGAGGAGGTGGCCGGTCACACCAGGAGGCTGCAGGATGTCTACCGGCGAGAGAGGCAGCGTCTGGAACGGGCGCACGCCCAGGgatcgacgacgacgacgtcccCACGCTGGTACTACGAGAGGTTGGGCTTCCTGGCGAAGAGTTTGCGCCGGAAGCGGCATCCCAAGATGTCCCTatccgtgcccgtgccccatCTAAACCATCAGCAGTGCCTGAAGCTCATTGAGATCTATCGGCAGTGCAGCGACACCTGGGACATGCAGGACTTGTCCTGCCGCCTGCGTCACGTACGAGATGCGGCCAAGGAGAAGCTGCTGGCGCTGTGCCGCGCCGAGCTGCACATGCCCCAGCTGGAGCCCTCGCTGCTGCAGCGCTACACCCGATATCTGCGCAACGCCTACCAGCAGGAGAAGATGCGACGCATCCAAAGCGAGCGCAAGGGCAGTGCCGGTGGCGGCGTGGTCTTCATCCCCCGTTGCCGCTACTACGAGCAGCTGCGTTTCCTCGATCCGCACGTGGCTCCCTTTCAGTGTGATCTCTGCGAGCAGCTGCTGAACAGCGTGGACGTCTACAAGGTGCATCGGGCCGGGCACGACGGCAGCCTGCCGTTCGTGTGCCCCACCTGCGGCAGGGGCTTCTCGCGCAGCGGCAACTGCACGATCCATCTGCGCCGGCATACGCACGACTACCAGCTGGGCTGCGAGGAGTGCGGCAAGCGGTTTGCCACCACCTCAGATCTGCAGGTCCATCGGCGTTCGCACACCGGCGAGCGGCCCTTCTGCTGTGACATCTGTGGCAAGCGCTTCAGCACGCGGTCCTTTTTCGAGCGTCATCGGCGGCGGCACGAGCAGCGGCCACGCGGCAAGTGCCACATCTGCGGCAAGAGCTTCTTCGAGCAGTCCGTGCTGAACGACCACATCAAGGGGCATCTGAATGTGCGCGACAAGGAGTGCGACATCTGCCACAAGACCTTCACCAGCTGCAAGTACCTGCGCCAGCACAAGGAGATCCACAATCCCCAGAAGCGATACATTTGCAAGATATGCACGAAGGGCTTTGCCCAGTACGCGGGACTCAGTGGCCACATGAAGTCACATGGCCGCACAGTGCCGCCCGATCCGAAAACTATGCTAGAATATCCATCCAATGGCTGCGCGGAGAGGCAACTGTAG
Protein Sequence: MPPYQRCGEIVWLGKRQTTAFAFQCIYCRDEEQTRTLKEFKSHLESKHADLFEDQKTAQTATASDTTLRRSGASKEQAFEPELAIGKVEREAEPPVDNALPLPDATAAAAAADPLSDADDDASEECFESETMLYWPSQSDGQSTTSQECYNEASLALCPGAGTCTDTTYFWLQEHPIMLAFIGQLEEQRLLWDLGMLAYRNYKHRSEACTTIAERLNSQFGLQLTGEEVAGHTRRLQDVYRRERQRLERAHAQGSTTTTSPRWYYERLGFLAKSLRRKRHPKMSLSVPVPHLNHQQCLKLIEIYRQCSDTWDMQDLSCRLRHVRDAAKEKLLALCRAELHMPQLEPSLLQRYTRYLRNAYQQEKMRRIQSERKGSAGGGVVFIPRCRYYEQLRFLDPHVAPFQCDLCEQLLNSVDVYKVHRAGHDGSLPFVCPTCGRGFSRSGNCTIHLRRHTHDYQLGCEECGKRFATTSDLQVHRRSHTGERPFCCDICGKRFSTRSFFERHRRRHEQRPRGKCHICGKSFFEQSVLNDHIKGHLNVRDKECDICHKTFTSCKYLRQHKEIHNPQKRYICKICTKGFAQYAGLSGHMKSHGRTVPPDPKTMLEYPSNGCAERQL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00611558;
90% Identity: -
80% Identity: -