Basic Information

Insect: Drosophila subsilvestris
Gene Symbol: Hivep2
Assembly: GCA_035043285.1
Location: JAWNNB010001922.1:5413118-5421669[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.0003 0.021 15.3 0.4 1 23 289 311 289 311 0.98

2 8 0.00032 0.023 15.2 2.9 1 21 317 337 317 341 0.89

3 8 0.044 3.2 8.5 0.1 1 19 963 981 963 984 0.93

4 8 2.9e-06 0.00021 21.7 2.0 1 23 1716 1738 1716 1738 0.99

5 8 1.2e-05 0.00088 19.7 5.3 1 23 1744 1768 1744 1768 0.92

6 8 0.00016 0.012 16.2 3.1 2 23 2236 2257 2236 2257 0.97

7 8 8.4e-05 0.0061 17.1 0.8 1 23 2263 2287 2263 2287 0.91

8 8 0.0027 0.19 12.3 2.7 1 23 2308 2332 2308 2332 0.92

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.0003	0.021	15.3	0.4	1	23	289	311	289	311	0.98
2	8	0.00032	0.023	15.2	2.9	1	21	317	337	317	341	0.89
3	8	0.044	3.2	8.5	0.1	1	19	963	981	963	984	0.93
4	8	2.9e-06	0.00021	21.7	2.0	1	23	1716	1738	1716	1738	0.99
5	8	1.2e-05	0.00088	19.7	5.3	1	23	1744	1768	1744	1768	0.92
6	8	0.00016	0.012	16.2	3.1	2	23	2236	2257	2236	2257	0.97
7	8	8.4e-05	0.0061	17.1	0.8	1	23	2263	2287	2263	2287	0.91
8	8	0.0027	0.19	12.3	2.7	1	23	2308	2332	2308	2332	0.92

Sequence Information

Coding Sequence: ATGGAAAATGCAAGCACCACAACGGCGGGCAAGCATTATAAGACGGCGGGAAAACAGTACAAGACAAACATCGGCGGCAATAGCCACAAGGATTCGCCACTGGCAGCCGCCACTACTGgcacaagcaacagcagcatcatcagcagcagcatcagcagcagcagcattacccccgccagcagcagcagcagtagcagcatgacagccaccacagcagatgaggctgctgctgttgccattgcgGACTGGCCAAATATCTCTCGCTATTTGCACAAGAAGTTCAAGCGTTTGGCGAGCACCACAGAAGTGGAGGGTGGTGGCAAcggcagtgggagtggcagtgtCAGCCACATTGCAGCCGGGGATGCCGGCCGCACCACATCGCTATCCTCAAATAGCTCACTTTCACCGccgccgcagccacagccgatgGTGCTGGGGCcggtggcagtgccagtggccaACGGTCATCATTTgacccaacaacagcagcagcaacagcagcagcagacgacgaCGAATGAATTCAGTGCCAATTTTGTAAATAGCAATCATGTCAATGCCATCAGCCATGaggagggcagcagcagcagtagcagcaacaacattcaCAATAACAGCCACAGtgcaagtggcagtggcagtgggagcgGGAAGATGGCCAACAATGTGAGCGTGCCCAGAAATCGTACACCGTtgagcaacagccacagcagcaactaTGCGGCCAATGCCACACTGACGCCTGCAACATTTgcccagcatcagcaacagacgcaaccaacagcagcaggaggaggaggagcagctatagcagccacagccgcagcaggcGGAGCACTAATAGCAGAGAAATCTGGCAGATATAAGTGCCCGTATTGTCAGTTGATTTGTGCCAAGCCATCGGTGCTGGAGAAGCATATACGTGCGCACACCAACGAGCGGCCCTATCCCTGCGACACCTGCGGCATTGCCTTCAAAACGAAGAGCAACCTGTACAAGCACTGCCGCTCCCGGTCGCATGCGGCACGTGTGCGCGGCCTGGAGGTGCCCGCAGATGCGGACGATGGCCTGTCCGACCAGGATGCAGATctgagcaacagcagctccgAATTGCCAAGTCGCTCGGGTTCGCCGTTCGATGAGCCCATGGCCTCGCCCACGCCATCGCCCTCCACTTTGTCGGCAGCGAAGAGCGCCTACATCCAGCACCAGCCAACGCTGCCGCAGCACATGCAACAACTGCCGCTGGGGTCGCCGGCTGCGGGCaccctgccacctgccaccgCGGACACCCTGCACTCGGCCACGGCCCAGCATCGTCAGTCCATCGATTACAAGCCATACAAGCCCAAGTTCCATAATGCAGCTCTCTATGTGCCGCctggcagcagcaaagagttgcagctgcaacaacaacagcaactgcagcagcatcatctcgtccagcagcaacagcagcaacagcagcagcagcaacagaagcttTCCATTCAGCTGCCtctggtgcagcagcagcagcagccagcgctGACCCATCCCACACTGTCGCCCAGCACACAGATGAAGCTGAACAATCACATCACCTCGCAcaagatgcagatgcagttgcagcagcagctgcacgcCCAGCAgtccctgctgctggctgccaatCCTGGGGCTTTGCCACCGGGAGCAGGTGTCTACTATCTGGGGCAGCCATCGTATTACAATCAggatgctgcagcagcggcggcggccatGCATCAGCAGGCCATGGTCTTTCAACAATTGCAAATGCAACAGATTCatctgcaccagcagcaacagcagcagcagcagcaacagcaacaacaacagcaacactcTCCACTGGTGAAGGCTCCTCCGCCAGcgatgcaacagcaacagcagcagcagcatccagcgaatattcctccgcaacagTTGGTGCGTGCCAATAGCCAGGCAGCGATTGTGGTGccagtagcaggagcagcaacagcaggaccACAAACACCCAGCACGCCAGCCACCAACCTGAGCAGctttgccagtgccagtggcggCATGCAAGTGAATGTGGAAAAGGTGCAGGAGCACATATCGAAGCTGATTTCGCAGAACGAGGCGATTGTGGAGAACAAGGAGATTCTGCTGCAGAAGAAGTACCCAAAGCAGCTAAATCGTTCGCGCAGCTTCAACAATGCCAATGCGAGTGCCAGCAATGCGGCTGTCAACAGTAGCCAAAATCCACAGATGTTGGGCATCGGTGCCAGCGAACGAGAGACGAAAGTGAATCTCGCTCAGGCCATTgtacaaaaacagcagcagcaacagcagatacagcaacagcagcagcaacactacCAAATGTATATGCAACaacaagtgcagcagcagcagcagcagcagcaacaacaaccactggAACCGCCAAATGGTGTGGTGAAGCGGAATAGCTATAGCTACAAGCCAGCACCGGCCATGCCAACAGCCgccaagcaacagcagcagcagcagcaccaacaacaacaactccagcaacaacaattgccaCCGCCACCCTCACCGCTGCCAATGCAAACGCTACAGTATCGGCAGGACCCGGCGACGCCAGTGCCCAAAATGGAGCAGCCAGCGGCCGCTGGCAATGCCATGCCATTGAATCTTTCTGCCAagccaaagcaacaacagccgaCACCACAGGCCACTGCCATGCCCACGCACACGCCCGCCTCTGCGCCCACTCCCTCGacgagtgcagcagcagcagcagcgggaagTTCTACAAAGATTCCCTCAGCCGCTGCACCCCAAACGCCAAACAATTCAATCATCAAGAATCTGCTGCTGAATGCCCGAGGATTGGCCGTGCCCATTGGCGAGGGCGACGACGCCTTCTACTCGTGCCCCATCTGTGCCAGCGAATTCCGCAGCGCGGACGAACTGAAGCTGCACAACAGCACCTACTGCCAGGACGCCAGCTCCAGTGCACCGATGAGTCCGGCCTCGTCGCCGAGCTCCAAGTACTTTCGTTCCAATTCGATCTCGATGAGCCTGCCAGAGCTCAAGTGTCACATGGCCAACTCCAAGAATCCGCTGTCGCTGGCCAAGCTCGCCTGGTCGCAGCTGAAGACGAAGCGCAGCAGTCTGGTGCTGAGTCGCCTCAGTGCCGCACAATCTCCCGCAAGGACATCGACGGTCACAGCTCCCACGCCAGCTGCTCCTGtccaggtgcaggtgcaggtgcaagTGCAGATCCCTGTCCCCATTCAGGCTCCCATTTGTGTGCCCGTGGAAGCGATGCGTTTTGTGGACGCGCCACTACCATCGCCTGGTCCTTTGCTTGGCAAGACAGCACTGGTGGACTTCGCCCAGCAGAATGCGCCCCGCAAGGCACACGATTCGGTGGTGATCACCAAAATGCACGAGGATCGGCAGTTTTCGATGGGCATGGACGCTGCTGCACAGCCTTCGCCGCCAGCGAAGCGTGCGAAGACCAGCGACACGCCAACGTTCAAGTTCTTTGGCAATCCCAACCACAACATGAGCTTGGtccaggagctgcagcagcagtccagcAGCAAGGAGGATCGCCTGCGCAGGCTAACCTCATCCGGCGGCACCATGATACCCATTTCGGAGTGCCCCGAACTGGAGAACAGCCCCAGGATGATACGCACTCCGCTGCTCTCGGGTGGCAGCTTCCAGGACGTCCTGCCCAAGAACCAAGAGTCGTCGGCCAGCAAGGAGCGcaagctgctggctgctggccttGGCGGTCACCCGTTGCTCGGTGTCAGCAGTGCCCAAGCGGCACAGCACTTCCAATTTCCGCCCATCAACTCGATAACTGCCTTCAATCCACTCACGCTGCCGATGagtggcggcagcggcggcggtggggATAAAACGGCACCCGTCACGCCTATACCGTACGTGCCGGGCATTCCGGGTCCCGGCAGCCTGACGCCCCAGATGTCCCTGCTACCGCCGCCaccgcagcagctgcaactgccgcTAGCTCCCGCCAGTCGTGGCCGCAGTCCCAATCGTAAGCAGCCGagcccgctgctgctgttgggagGAACAGCAGGATCAGCAGGCGAGTCGCTCAAGTCGCTGTCGCCGTTCGGCGGCGTCCAGAATCTCCCAAGTGAGTTCAGCCGCCAGCCGCCGACGCCTGCCCAGAGGAACGCCCTGCAGTGGAACAGCAGCAAGGAGACGCCCAAGAAGGCGCCCTTTAACTTTCTGCGCATGGCGGACAATGTGAAGGCATCGGAGCCGGAGGTGCGCCACTTTAACCTGGACAATGTGATTGCTGTCAAGCAGCCGTCACAGGAGGCGGCACCATTGCCGCCACTGCACGTGGACACGCCCAATGGGAGTGCAGGTGGAGCTGACGCCGTCGTGGCagtagctggagctggagctggagctggagaggAGGCGCTATCCGCCGCCAAATCAAAGTTTCTGCGTCCCACGAGTCTGCCCCTGAAGCCGGGCACCTTCACACCGAAGCGCCATCATGGCATCACGCCGACTGCCAACACCCTGCCGCTGATCTCGCCGGAAACGCCGCGTCCGTCCAAGTCGTGTGTCCAGCTGTATCTGAACGGCCATGCCTACACCTACCTGGGGCTGAAGTGCAGCACCAAGATGTTCTACTGCACCGTGAACTGCCCGCAGCCGTCGTATGTGGCGGGCATGCACAAGCTGTCGATGTACAGCGTGTGGCAGGTGTGCGAGGAGAACCAGCCGCATCCGCTCGGATTCAAGCTCAAGCAGGTGATGGCACTGTACGACTCGCGCCAGAAGATGTTCGGCAATGGCAGCTGCATCTCGATGGCGGGCACGGGGACAGGTGCAGGCACAGGCCCGGGCACAGGGAAGCTGCTCAGCTACAAAGTGGTCAACTCGCAGCAGACCATCTGCTCCGTTTCCACAATCTCCAGCAGTGCACTCCATCAGAATCCGCTGGCTCCACTGCCGGTGGTGGCCGTGGGGGCACTCAGCGAGGCGAATGTGGCGGCCAAGGCCTGTGAGGAGGCGGCCGAGGACAAGAAGATGGAGGTGAGTCCCACGGGACAGCCCCTGGTGGGCGGTTATGAGTCGCACGAGGACTACACCTACATCCGGGGACGGGGACGCGGTCGATATGTGTGCTCCGAGTGCGGCATCCGCTGCAAGAAGCCATCGATGCTCAAGAAGCACATACGCACCCACACGGACGTGCGTCCGTTCACCTGCAGCCACTGTAACTTTAGCTTCAAGACCAAGGGGAATCTCACCAAGCACATGCAATCGAAGACGCACTTCAAGAAATGCATCGAGCTGGGCATCAATCCCGGTCCCATGCCCGCCGATGGCGAGTTCCTCGATGTGGACATGGACTTTGATCAGCAGTCATCGACCTCTGCGGGCGGACGCACCTCCTCGATGGCCGATGGCGAATCCGATTCGGATGATTTCAGTGACATTGAATCCGAGAGCAGTGACACCGACGAATCCAAGTCGCGACTGAAGGAACACGAGGCCGCTCGCTgcctgctgtcgctgtcgatgACGCCGCCCATACCGCAGAGCGTATCGCCATATCCGCAGCTTCAGGAGACACCGGCACCGGCTGGCAGTCCGGCCAACAGCATTGGCTCCTCGGGATCGTCGCAGCCCAAGCCCCGTGGCGTGGTGTGCTCCTTTACGTCGCCAAAGCCGCCGTTCGACTACCAGAAGCAGGAACAGTATTACTCGAATCCCGAGGAGTCCAAGCCCAAGCGGAGCGTGGCCAGCGAGGAGAGTGCGCCCATGGATCTCACCAAGCCACGATGCTCCAGCACACCGATGGCCGCCGTCTCCCCATCCCACTCCCTGGTGGCGCTGGCACAGGACTTGCCCAAGTCGCAGGCACAGCAGATGCACGATGTGATCTTTGGCAGCgctggcagcagtggcagtggcttcATGAAGACCCTCATCTCGGTGTCGGACAAGGTGCGCATCTCCACCGAgttgaaggaggaggaggagcaggccaTGCACGAGGCGGCGGAGGGCGAGGATGTGCTGATGCAGACGTACCGCAAGGAGCATGCCCTGCAGCATGCCAAGATGAAGCAGAGCCAATTCAGTCGCAGCTACCTGATCAGCACGCTCTtctccagcaccagcaccagcgccaCGACCTCCTCCGTCATGACCACTagcactagcagcagcagcagcagcaacctccTCTCCGTGAGCAGCAGGCCCATCATGAGCATCAATGAGGTGCCCAGCATCGAGGTGCATGAGGTGAAGACCCCGGAGGCGGTCGAGGTTTCGCTTCCATCGACATCCACGACAGCGGCTACGTCTGCGATCATCAGCACCCCCTCGAAGGCAACGGCCAACGATGAGAGCGAGGAGAGTGAGGCGCAGTCGGATCAGGAGAGGGCAAGCGAGACGGCGCACAATGCGAATCTCCCTGCTGCAGTGCAGCAGCCGGATGCCACAGACTTTAGCGGTGTTCTGGCCGCACCAGCTGCAACTCCAACTGCAACTCCTCCAGTGtcatcgcagcagcagcagcagcagcagcagcagccgcaaccgcAGCCGCCCACCCGCACTGTGATCGTTGGCGAAGATGGCTTCAAAAGCGCCTCGCCTGGAGCTGTGTCCACATATCCGAGGGGcgtgccaccgccgccacccacTGCCAGCGATGCGAGACCGACGTGCTTGATCTGCTCGAAGACGTTCCAGCGCCAGCACCAGCTGACGCTGCACATGAACATCCACTACATGGAACGGAAATTCAAGTGCGAGCCGTGCGGCATCTCCTTCCGTACCCAGGGCCACCTGCAGAAGCACGAACGCTCCGAGGCGCACAAGAACAAGGTGATGATGACGTCGACGTTTGGGGTGCCGACCACCTCCAATCCGCGGCCATTCGAGTGCACCGACTGCAAGATCGCCTTCCGCATCCACGGCCATCTGGCCAAGCATCTGCGCTCCAAGACACACGTCCAGAAGCTGGAGTGCCTGCAGAAGCTGCCGTTCGGCACCTACGCGGAGATCGAACGCGCCGGCATCAGCCTCACTGAGATCGACACCAGCGACTGCGACAACTCGCTCATCTCCCTCAAGCTGCTCGCCCagaagctgctggagaaggatCCCAACAAGCTGAGCGGCTACACCACGCCCTCGGGCATGATGCAGCTGGCCCAGGATACGCCCACCTCGCAGGATAGCGCCTCTGAGGATGGGTTCAGTGCGGCCATCGCCTCGGCCATTGCCAGGCTGGACAATGACAGTGATGGCAACACGCCGAAGCGTGCCAGCTCCATGTCCGAAGATGAGACCGTGGCCAATGGGCTCACCCACAACCTGAAGCGTCGTCTGCCCGGCAGCTTTAGCAGCACGGGCGGCGAGGAGAGCGACAACCCAGCGGAGGGCGGCACCACCACAGCCGCCAACGAGAAGCGTGCCCGACCATCCCAGGATGGTGGTGgtccgcctctgcctctgcccctccCCGTTGCCGCTACCGTACCCGTTGCCGTTCCCGTGGTCGCCTCGGCAGCGGCCAGCAACTGA
Protein Sequence: MENASTTTAGKHYKTAGKQYKTNIGGNSHKDSPLAAATTGTSNSSIISSSISSSSITPASSSSSSSMTATTADEAAAVAIADWPNISRYLHKKFKRLASTTEVEGGGNGSGSGSVSHIAAGDAGRTTSLSSNSSLSPPPQPQPMVLGPVAVPVANGHHLTQQQQQQQQQQTTTNEFSANFVNSNHVNAISHEEGSSSSSSNNIHNNSHSASGSGSGSGKMANNVSVPRNRTPLSNSHSSNYAANATLTPATFAQHQQQTQPTAAGGGGAAIAATAAAGGALIAEKSGRYKCPYCQLICAKPSVLEKHIRAHTNERPYPCDTCGIAFKTKSNLYKHCRSRSHAARVRGLEVPADADDGLSDQDADLSNSSSELPSRSGSPFDEPMASPTPSPSTLSAAKSAYIQHQPTLPQHMQQLPLGSPAAGTLPPATADTLHSATAQHRQSIDYKPYKPKFHNAALYVPPGSSKELQLQQQQQLQQHHLVQQQQQQQQQQQQKLSIQLPLVQQQQQPALTHPTLSPSTQMKLNNHITSHKMQMQLQQQLHAQQSLLLAANPGALPPGAGVYYLGQPSYYNQDAAAAAAAMHQQAMVFQQLQMQQIHLHQQQQQQQQQQQQQQQHSPLVKAPPPAMQQQQQQQHPANIPPQQLVRANSQAAIVVPVAGAATAGPQTPSTPATNLSSFASASGGMQVNVEKVQEHISKLISQNEAIVENKEILLQKKYPKQLNRSRSFNNANASASNAAVNSSQNPQMLGIGASERETKVNLAQAIVQKQQQQQQIQQQQQQHYQMYMQQQVQQQQQQQQQQPLEPPNGVVKRNSYSYKPAPAMPTAAKQQQQQQHQQQQLQQQQLPPPPSPLPMQTLQYRQDPATPVPKMEQPAAAGNAMPLNLSAKPKQQQPTPQATAMPTHTPASAPTPSTSAAAAAAGSSTKIPSAAAPQTPNNSIIKNLLLNARGLAVPIGEGDDAFYSCPICASEFRSADELKLHNSTYCQDASSSAPMSPASSPSSKYFRSNSISMSLPELKCHMANSKNPLSLAKLAWSQLKTKRSSLVLSRLSAAQSPARTSTVTAPTPAAPVQVQVQVQVQIPVPIQAPICVPVEAMRFVDAPLPSPGPLLGKTALVDFAQQNAPRKAHDSVVITKMHEDRQFSMGMDAAAQPSPPAKRAKTSDTPTFKFFGNPNHNMSLVQELQQQSSSKEDRLRRLTSSGGTMIPISECPELENSPRMIRTPLLSGGSFQDVLPKNQESSASKERKLLAAGLGGHPLLGVSSAQAAQHFQFPPINSITAFNPLTLPMSGGSGGGGDKTAPVTPIPYVPGIPGPGSLTPQMSLLPPPPQQLQLPLAPASRGRSPNRKQPSPLLLLGGTAGSAGESLKSLSPFGGVQNLPSEFSRQPPTPAQRNALQWNSSKETPKKAPFNFLRMADNVKASEPEVRHFNLDNVIAVKQPSQEAAPLPPLHVDTPNGSAGGADAVVAVAGAGAGAGEEALSAAKSKFLRPTSLPLKPGTFTPKRHHGITPTANTLPLISPETPRPSKSCVQLYLNGHAYTYLGLKCSTKMFYCTVNCPQPSYVAGMHKLSMYSVWQVCEENQPHPLGFKLKQVMALYDSRQKMFGNGSCISMAGTGTGAGTGPGTGKLLSYKVVNSQQTICSVSTISSSALHQNPLAPLPVVAVGALSEANVAAKACEEAAEDKKMEVSPTGQPLVGGYESHEDYTYIRGRGRGRYVCSECGIRCKKPSMLKKHIRTHTDVRPFTCSHCNFSFKTKGNLTKHMQSKTHFKKCIELGINPGPMPADGEFLDVDMDFDQQSSTSAGGRTSSMADGESDSDDFSDIESESSDTDESKSRLKEHEAARCLLSLSMTPPIPQSVSPYPQLQETPAPAGSPANSIGSSGSSQPKPRGVVCSFTSPKPPFDYQKQEQYYSNPEESKPKRSVASEESAPMDLTKPRCSSTPMAAVSPSHSLVALAQDLPKSQAQQMHDVIFGSAGSSGSGFMKTLISVSDKVRISTELKEEEEQAMHEAAEGEDVLMQTYRKEHALQHAKMKQSQFSRSYLISTLFSSTSTSATTSSVMTTSTSSSSSSNLLSVSSRPIMSINEVPSIEVHEVKTPEAVEVSLPSTSTTAATSAIISTPSKATANDESEESEAQSDQERASETAHNANLPAAVQQPDATDFSGVLAAPAATPTATPPVSSQQQQQQQQQPQPQPPTRTVIVGEDGFKSASPGAVSTYPRGVPPPPPTASDARPTCLICSKTFQRQHQLTLHMNIHYMERKFKCEPCGISFRTQGHLQKHERSEAHKNKVMMTSTFGVPTTSNPRPFECTDCKIAFRIHGHLAKHLRSKTHVQKLECLQKLPFGTYAEIERAGISLTEIDTSDCDNSLISLKLLAQKLLEKDPNKLSGYTTPSGMMQLAQDTPTSQDSASEDGFSAAIASAIARLDNDSDGNTPKRASSMSEDETVANGLTHNLKRRLPGSFSSTGGEESDNPAEGGTTTAANEKRARPSQDGGGPPLPLPLPVAATVPVAVPVVASAAASN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00474011;
90% Identity: -
80% Identity: -