Basic Information

Insect: Drosophila subsilvestris
Gene Symbol: -
Assembly: GCA_035043285.1
Location: JAWNNB010000653.1:896160-897524[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 0.0037 0.27 11.9 7.8 1 23 154 176 154 176 0.98

2 6 2e-05 0.0014 19.1 1.3 1 23 182 204 182 204 0.99

3 6 7.5e-06 0.00054 20.4 0.4 1 23 210 232 210 232 0.98

4 6 1.2e-05 0.00084 19.8 0.2 3 23 240 260 238 260 0.97

5 6 0.00014 0.0099 16.4 4.4 1 23 266 289 266 289 0.95

6 6 1.8e-07 1.3e-05 25.5 0.4 1 23 323 345 323 345 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	0.0037	0.27	11.9	7.8	1	23	154	176	154	176	0.98
2	6	2e-05	0.0014	19.1	1.3	1	23	182	204	182	204	0.99
3	6	7.5e-06	0.00054	20.4	0.4	1	23	210	232	210	232	0.98
4	6	1.2e-05	0.00084	19.8	0.2	3	23	240	260	238	260	0.97
5	6	0.00014	0.0099	16.4	4.4	1	23	266	289	266	289	0.95
6	6	1.8e-07	1.3e-05	25.5	0.4	1	23	323	345	323	345	0.99

Sequence Information

Coding Sequence: ATGGACTATAATATTCACAAGATCTGCCGGGTTTGCCTGGAGGAGGGCACCCCGGCAGGACCCCTGACGTCCATCTACAGCACAGACTTTGCCATGATGCCCTCTGTGATGCTGATGCAGTGCGCCAAGATACACGTTTACAAGACGGACGCTTTGCCATCGGTTATCTGTAATAATTGTATTTACCGCCTGGGTGTAGCTTTCCATTTTAAGCAGCAATGCGAGAACAGCGATCTGAGACTGCGTCAATATTTGGGTGTACTCGAGTCCTGGCGTCAGGATGCAGCCACCAACACGGACTTTGTAGAGAAACCCTTGCCCCCGAGTCGTGCACTGATCTCCagtgatgaggaggaggagagaacGGAAACGAAGACGAGCAAACGACGTTCGCGCTATCAGCGGAAACCGCCCGAACAGCACAAGAAGCGCGGACCAAAACCCCTGCCCAAGATGCCACACACCTGCTACGAGTGCCACAAGAGCTTCAAGTGCATTGCCCAGCTTACCCAGCACATACGAACGCACACGGGGGAGAAACCCTATCAGTGCGGCTACTGCATCCAGCGATTTGCCCAAAAGTACAACCTGAAGGTGCACGAACGCACCCACACGGGCGACAAGCCCTTCCAGTGCGAGATCTGCTCCAAACAGTTCTCGGCGCTGGGAAACTTTCAGGCGCATCAAAAGATTCACATCGGCGTGAGGGATCAAATCTGCTCGCTGTGCCAGAAGGGCTTCTACACGGCCGGTGATCTGTCCAAGCACATGATAACCCACACTGGAATAAAGAACCATCATTGCGATGTTTGTGGCAAGGCCTTCAGTCGGCGACGTGATATGCGCTCCCACAAGCTAAAGCTCCATCCTTTGGACTCCAGCACGGACATTGtggatgatgacgatgatgagcCCATAGACACAGATCCCGTGGGTCTGGATACCCTCGACGATGATCATGCCCCTTTCAAGTGTCCCGACTGTGATAAAGCCTTCGATACTGCCGACAGTCTGAGCTTGCATTTCCGCACGCACGCAGTGAACAACAATCACCTGAATCTGCCCTTGCCGCCCGCTCCGCCCATGTCTCATCActaccatcaccatcatccgGCAGGGAGTGGACCGTCCTCAGCAGCCATGCATCATCACGATGCGCTGCATCACCTGGGCCCGCCGAATGCAGATTGGATGGGAATGGCTGCGATGGCACATATGCTggcaccaccgccgccgccgccacctaCTCCCATTGAGGGACGCTACTCAATGCTCCATCACACGGCCGCCCAAAGGTTGCATTACTAA
Protein Sequence: MDYNIHKICRVCLEEGTPAGPLTSIYSTDFAMMPSVMLMQCAKIHVYKTDALPSVICNNCIYRLGVAFHFKQQCENSDLRLRQYLGVLESWRQDAATNTDFVEKPLPPSRALISSDEEEERTETKTSKRRSRYQRKPPEQHKKRGPKPLPKMPHTCYECHKSFKCIAQLTQHIRTHTGEKPYQCGYCIQRFAQKYNLKVHERTHTGDKPFQCEICSKQFSALGNFQAHQKIHIGVRDQICSLCQKGFYTAGDLSKHMITHTGIKNHHCDVCGKAFSRRRDMRSHKLKLHPLDSSTDIVDDDDDEPIDTDPVGLDTLDDDHAPFKCPDCDKAFDTADSLSLHFRTHAVNNNHLNLPLPPAPPMSHHYHHHHPAGSGPSSAAMHHHDALHHLGPPNADWMGMAAMAHMLAPPPPPPPTPIEGRYSMLHHTAAQRLHY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00612989;
90% Identity: iTF_00515087;
80% Identity: -