Basic Information

Insect: Drosophila subsilvestris
Gene Symbol: prg
Assembly: GCA_035043285.1
Location: JAWNNB010001739.1:53261-55075[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.29 21 5.9 1.0 1 23 221 244 221 244 0.95

2 9 0.0043 0.31 11.7 3.4 1 23 250 272 250 273 0.95

3 9 1e-05 0.00072 20.0 0.3 1 23 279 301 279 301 0.97

4 9 5.8e-09 4.2e-07 30.2 2.6 1 23 307 329 307 329 0.99

5 9 0.00037 0.027 15.0 0.7 1 23 335 357 335 357 0.97

6 9 0.00048 0.035 14.7 2.6 1 23 363 385 363 385 0.98

7 9 9.9e-06 0.00071 20.0 0.6 1 23 435 457 435 457 0.96

8 9 1.8e-05 0.0013 19.2 0.3 3 23 464 485 462 485 0.92

9 9 0.097 7 7.4 0.8 1 23 489 511 489 511 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.29	21	5.9	1.0	1	23	221	244	221	244	0.95
2	9	0.0043	0.31	11.7	3.4	1	23	250	272	250	273	0.95
3	9	1e-05	0.00072	20.0	0.3	1	23	279	301	279	301	0.97
4	9	5.8e-09	4.2e-07	30.2	2.6	1	23	307	329	307	329	0.99
5	9	0.00037	0.027	15.0	0.7	1	23	335	357	335	357	0.97
6	9	0.00048	0.035	14.7	2.6	1	23	363	385	363	385	0.98
7	9	9.9e-06	0.00071	20.0	0.6	1	23	435	457	435	457	0.96
8	9	1.8e-05	0.0013	19.2	0.3	3	23	464	485	462	485	0.92
9	9	0.097	7	7.4	0.8	1	23	489	511	489	511	0.98

Sequence Information

Coding Sequence: atgtatattacgCAGATTGAGGCTCCACGGGCCCCGCCAAAAGAGAGCCAAAACAGTGCCAGCTCGTGCCGCCTGTGTCATCGGCCGGCAACGACGGAAACCACGCCAAACATTTTCACCGATCGCGAGGGTTTCTGGGATGGAGACAAATTCTGCATTGCCGATGTCTGCCAGAGCGTGTGGGGCGTTCAGTACGATCGGCACGAGTATTTGCCGGAACAGATTTGCTCCGATTGCTTGGAAGTGCTGGAGGATTTCTATAAGCAACGGCGGGGAATGAAGGAGCGGGAAGCTGCCTTACAGGAGCAACTGAAGGAGATCATTAAAAAGGATCCCAAGTACCGGCCCGGCTTGAACGGGAATCCTGGTGAATTTGAGGCCGGAGATGATTGTGAAATTGAGGTAGTGGATCCGGATAAGGTGGCGGAGACGAGCGATGATGAGATGGGCTCCGATGAAGAGAATGACAATGCAGAGGacgaggaggaagaggaggagttCGAGGACTTTGAGGAGGACGAAGCAGACACAACAAATGCAGATGATGCCGACATGCCTTTGGGCACAGATGCGGCTCAAATGGCCAAAATGGCGGTGCAAATGGAGTTGGAGCAGCCCAGTGTTGTGGCCAACTCTGGAGGAGCACGTCCGAAGACCGCTTTTCTGTGTCAGTTCTGCGACTTGGGCTACACCCTTCCATCCGAGTGCCAGCAACATGAGAGAACGGCCCACGATCCCCATGCACCGTACTGTTGCACGTTTTGCAGTTTGCTTTTCATCACGCGTGCCACATTGATTGCCCACATCAAGTCACATCATGATATGGATCGTCCCTATGTGTGTGCCCAGTGCAGGAAGGGATTTGTACGCCGCTCCGACCTAAAAAAGCACGCCATTGTCCATACCGGCGTGCGGCCCTACACCTGCAATGTATGCACAAAGAGCTTTTCGCGAAACACCAATCTCACGAAACACATGCGCATTCACAGCGGAGAGAAGCCCTTCGTGTGCCAGCAATGTCCACGCTCCTTCCAGACCGCCCAGGAGATGACGAACCACTCGCGTTTGCATACCGGGGCCAGACCCTTCCAGTGCAACCGCTGTCCCTTTTCCTCCTCGCGCAAGGACAAACTGGTTGCCCATCAGCATATGCACACTAAGCGCGACGTTGAGCAGAtactacagcagcagcaacaaaacgcTCTGCATCCCCCGACAGCGGAGGAGCTAGCGCAACTACAGCACGAGCTGACGCAACAGTTAAAGCCGAAGCCGATCACCCCACAGAAGCCAGGACGCAGTTTCCGGTGCGATGTCTGCGACAGGGTCTTTCAACGGGAGCGCGATCTTCAGCGCCATCGGGCGCTGCATTTGGACACGCTGCTGGCCTGCAAAATATGCAATTTAGTCTTCAATCGTCGCGAACAACTGCAGCGTCACACACTGGAGGCTCACGGACCCACATATACGTGCGCCATTTGCTGTATTACCTTTTTGCAGAAGATTGAGCTGGAGAACCACCTGAAGGTCCATCAGCTGCAGCACAAGGTGGCCCAGAGCACCCAACAGGCCATGATTGCGGCAGCGATAATGCCCCACAAAATGGTCGAACCGACAGCGGTGGCCAAAATGCCTCCAGTGCCCCAGGTGCCGATACAGATGCGTCCCACAGCCGCCGAGCTCAACTTCTATAGCAACATGATTCCCACAATGAATCTGGGCTTCTATAGCGAAACGCGACCCGACGAATAA
Protein Sequence: MYITQIEAPRAPPKESQNSASSCRLCHRPATTETTPNIFTDREGFWDGDKFCIADVCQSVWGVQYDRHEYLPEQICSDCLEVLEDFYKQRRGMKEREAALQEQLKEIIKKDPKYRPGLNGNPGEFEAGDDCEIEVVDPDKVAETSDDEMGSDEENDNAEDEEEEEEFEDFEEDEADTTNADDADMPLGTDAAQMAKMAVQMELEQPSVVANSGGARPKTAFLCQFCDLGYTLPSECQQHERTAHDPHAPYCCTFCSLLFITRATLIAHIKSHHDMDRPYVCAQCRKGFVRRSDLKKHAIVHTGVRPYTCNVCTKSFSRNTNLTKHMRIHSGEKPFVCQQCPRSFQTAQEMTNHSRLHTGARPFQCNRCPFSSSRKDKLVAHQHMHTKRDVEQILQQQQQNALHPPTAEELAQLQHELTQQLKPKPITPQKPGRSFRCDVCDRVFQRERDLQRHRALHLDTLLACKICNLVFNRREQLQRHTLEAHGPTYTCAICCITFLQKIELENHLKVHQLQHKVAQSTQQAMIAAAIMPHKMVEPTAVAKMPPVPQVPIQMRPTAAELNFYSNMIPTMNLGFYSETRPDE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00487472;
90% Identity: iTF_00515078;
80% Identity: -