Basic Information

Insect: Drosophila subsilvestris
Gene Symbol: -
Assembly: GCA_035043285.1
Location: JAWNNB010001545.1:89584-91689[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.091 6.5 7.5 0.3 3 23 288 309 287 309 0.91

2 10 7.3e-05 0.0052 17.3 0.5 6 23 318 335 318 335 0.99

3 10 1.9e-05 0.0014 19.1 0.3 1 23 341 364 341 364 0.98

4 10 0.00016 0.011 16.2 0.7 1 23 376 398 376 398 0.97

5 10 0.0011 0.079 13.6 7.1 1 23 405 428 405 428 0.96

6 10 3.9e-06 0.00028 21.3 2.4 1 23 434 456 434 456 0.97

7 10 0.073 5.2 7.8 0.7 2 23 465 486 464 486 0.97

8 10 0.00038 0.028 15.0 2.0 3 23 493 514 491 514 0.95

9 10 1.4e-06 0.0001 22.6 1.1 1 23 520 542 520 542 0.98

10 10 0.0002 0.014 15.9 4.4 1 23 548 571 548 571 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.091	6.5	7.5	0.3	3	23	288	309	287	309	0.91
2	10	7.3e-05	0.0052	17.3	0.5	6	23	318	335	318	335	0.99
3	10	1.9e-05	0.0014	19.1	0.3	1	23	341	364	341	364	0.98
4	10	0.00016	0.011	16.2	0.7	1	23	376	398	376	398	0.97
5	10	0.0011	0.079	13.6	7.1	1	23	405	428	405	428	0.96
6	10	3.9e-06	0.00028	21.3	2.4	1	23	434	456	434	456	0.97
7	10	0.073	5.2	7.8	0.7	2	23	465	486	464	486	0.97
8	10	0.00038	0.028	15.0	2.0	3	23	493	514	491	514	0.95
9	10	1.4e-06	0.0001	22.6	1.1	1	23	520	542	520	542	0.98
10	10	0.0002	0.014	15.9	4.4	1	23	548	571	548	571	0.96

Sequence Information

Coding Sequence: ATGATTTGCAGATTATGCCTGCGCAGCATAAATCCCAGCAATGCTGTATTCCTGTTCGAAACGAACGAGACGATGGCGGAGACGACTCTGGTCAAGATGATTGCCAAATTCCTGCAACTGGAGATCACGCCCGACGACAGCATCTCGACGAGTGTCTGCACCGAATGCTGTGAGCATCTGGAGGACTTTAACACCTTCTGGCAGCTGGTGGAACAGAAACAGGGTACTCTCAAAAAGGAGTTCCTCACCGTCGACGTGGACTGCGTGGCGATGAAGTGGACGGGCGAGGTGGATGTGGACGTCAACATTGACGAGCTGCCGCTGGTGGCAGTCGAAATGGACGAGAAGCCCCTCGATATGCACAACCTCAGCCTGCTGGGCAGTGTgctggatgtgaatgtggacaGTGTGGAGGTGCCACAGGCGCCGCCAGTGGATATCAAAATTCAGCAGACTGATTACCTGTCCGAGGAAGACGACCATCCATCCCACCTCGATGCGTCTGACAGCGAGTTCGAGTGCGACGCAGTCGCCGAGGAAGACACCTCGGATGATGAGCCGCTGGTCAAGCTGCAGGACAAGCTGAAGCCCAAGCGCAAGTCTCACGTCCGCTCCACCAAGGCACGGGAAGACAACTGCCCAATCGGAGCTCAGGAGCTGAACTATCTGcttggcgatggcgatggtgaAGGCGAGGGCAGCAAAGGGCGTCGCAAAAAGGCGCCTGGCCAGCGGAGCATACCCACGGAGGTGCAGGAAAGCGAACTGCAGGCAGCGCTCGAGCGCAAGCCCAAGGGCTGCTCGCGTGCCCAGCTGGCCAAGCGGTACGAGGAAGTCATTGCCAGCTACATGAACGCCGACTGCGACCTGTGCGACTTCAGCGCCAAGTATCTGTCCGACCTGAAGGTGCACTTCCTGGAGACCCACCAGCGCGAGTTCTACATCAAGTGCTGCAACAAGGTCTTTACACGCGCCTCCAAGCTGATGGACCACATACGCAAGCACGTCAATCCCAAGCTCTTCACCTGCTCCATCTGCCAGAAGACGCTCAATTCGCAGGACTATCTGGCCACACACATCGAGACGGTGCACAACAAGGTGGAGAAGATCGACAAGGTGCTGCAGTTCCCCTGCTCCAAGTGCGAGCGCACCTTCAGCAGTGAGCGACGACTGGCCAATCATCTCGCTAAGCACGACACGGCGACGCTGGAGCACATCTGCCACATATGCCATAAAAACTTTGCCAATGTCCATCGGCTGCGCCGGCACATACAGTCCATACACGAGGATCTGCACCGGCATGTGTGCGACATCTGCGGCAAGAAGTTCAAATTTAAGCCCTCGTTCGAGCGGCATCTGCGCGAGCATCAAGGCGTGGTGGCCCCGACCATGCAGTGCCCCGTCTGCGGTGTCTGGCTGAAGAACGAGCACAGTCTGCGCCTGCATCGCTTCACCCACGACAGCACCAACACGGCCTGTCCCCACTGCGCGAAGACATGCAACTCGAGAACGGCGCTGCGCGCCCACATCAAGTATGCCCACAAGCTGACGACCAGCTTCCAGTGCACATACTGCGAGAAGACCTTTAAGCAGCAGCGCAACCTGGACGAGCACCTGGCCATCCACACGGGCCTCCAGCTGTACAACTGTCCGCACTGCCCCAAGGAGTGCCGCTCCCGGTCCAACATGTACGTGCACATCAAGCAGCGGCATGCGGAGGAGTGGCTCACCGCCAAGATGGCCCGCTCCCACAATCCGCAGTTCAAGCCGCACGCCTAA
Protein Sequence: MICRLCLRSINPSNAVFLFETNETMAETTLVKMIAKFLQLEITPDDSISTSVCTECCEHLEDFNTFWQLVEQKQGTLKKEFLTVDVDCVAMKWTGEVDVDVNIDELPLVAVEMDEKPLDMHNLSLLGSVLDVNVDSVEVPQAPPVDIKIQQTDYLSEEDDHPSHLDASDSEFECDAVAEEDTSDDEPLVKLQDKLKPKRKSHVRSTKAREDNCPIGAQELNYLLGDGDGEGEGSKGRRKKAPGQRSIPTEVQESELQAALERKPKGCSRAQLAKRYEEVIASYMNADCDLCDFSAKYLSDLKVHFLETHQREFYIKCCNKVFTRASKLMDHIRKHVNPKLFTCSICQKTLNSQDYLATHIETVHNKVEKIDKVLQFPCSKCERTFSSERRLANHLAKHDTATLEHICHICHKNFANVHRLRRHIQSIHEDLHRHVCDICGKKFKFKPSFERHLREHQGVVAPTMQCPVCGVWLKNEHSLRLHRFTHDSTNTACPHCAKTCNSRTALRAHIKYAHKLTTSFQCTYCEKTFKQQRNLDEHLAIHTGLQLYNCPHCPKECRSRSNMYVHIKQRHAEEWLTAKMARSHNPQFKPHA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00474705;
90% Identity: iTF_00580951;
80% Identity: -