Dsub015648.1
Basic Information
- Insect
- Drosophila subsilvestris
- Gene Symbol
- Gzf1
- Assembly
- GCA_035043285.1
- Location
- JAWNNB010002045.1:1452104-1455262[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 12 0.00079 0.057 14.0 2.3 1 23 193 216 193 216 0.97 2 12 2.3e-06 0.00017 22.0 5.1 1 23 221 244 221 244 0.97 3 12 3e-05 0.0021 18.5 3.3 1 23 249 271 249 271 0.98 4 12 4.2 3e+02 2.3 3.9 2 23 278 301 277 301 0.91 5 12 0.00067 0.048 14.2 3.9 3 23 312 333 311 333 0.95 6 12 0.0039 0.28 11.8 0.2 1 23 339 362 339 362 0.96 7 12 0.021 1.5 9.5 0.5 2 23 373 395 372 395 0.92 8 12 0.0012 0.084 13.5 0.4 1 23 423 445 423 445 0.97 9 12 5e-06 0.00036 20.9 3.5 1 23 452 474 452 474 0.97 10 12 0.00024 0.018 15.6 0.1 2 23 481 502 481 502 0.97 11 12 0.00015 0.011 16.3 1.1 1 23 509 531 509 531 0.99 12 12 0.00014 0.01 16.3 3.7 1 23 537 560 537 560 0.98
Sequence Information
- Coding Sequence
- atgGAAACTTGTCGCACCTGTGCGATTTCCATGTTTAGTGAAATGGCCCATATACGACTGGAGTTTGTCCACTGGAATCTGAAGATTTCTCCCAATGATGGATTGCCACAGAAGATATGCAGCGACTGTTTTACCAAGTTCTGCTCCATCTACACATTTCGACTGAGCTGCGAGGAGGCGCAGCTGAAGTTGTCGAACATTTATGATAAAATCGATGCCAGCAGCTTGGAGGATGACAACCAGGAAGAGGAAGAAGCGGATGCTGcgccaaaaacagaaacaattataggaacaaaatcaacaacaacaacaacgacggtTTCAACCGAAACACAACCaaacactgccactgccacgccaATAGAGTTTTTTGTGGAAACCATAGACTCCTACATAGAATCACCACAGCCACCATACCaggatgataatgatgacaatgatgatgataatgccACTGGATGCCAGGAACTGACCATTAGCTATGCCTGTAAGTACTGCTTCAAGCCGCAGGAGAGCtaccagctgcagcagctgctcctggaGCACATCAATGCCAGCCACGATCCCGATCAGCCGTACAACTGTCCGGAGTGTGAGGAGTGCTTCCAGGATGCAGCCTCCCGAACCGTGCACATGAAGAGCTGTCATGTGGAGAAGCAGTTCAAGTGCGAGGTGTGCGGCAAGAAGTACAGCGATCGCCACAATCTGCGCCACCACATTGAGAAGTATCACTCGGAGACGGACTTTGAGTGCACCATGTGCGAGAAGCGCTTCTTCACCCGCAAGAGTCTCACCTATCACATGAAGTGGCACAATCCGGAGCGGCAGCTCAAATGCCGCCAGACCGGCTGCGAGCGTTTGTTCATCAATCAGCGGCATCTCAAATGCCACGAGGCCACGCATACGGGCGCCAGTGCCAGAAAGAGCGAGCACTGTGGCTTCTGTGGTAAAACTTTCATACACCTAAAGACACTGCGATGGCACATCTATAGGCAGCATGGCGGGGAAAAGCCCTACAAATGTGCCAACTGCACGGAGGTGTTCGCCTCGTATGCCGAGAAAAGGATACACATGCTGGAGCGGCACAGGGAGAATCTAACGCCCATTGAGCGCAGCGAGTGCATGTTGTGCCGCCAGCCCTTTGGCACCGAGCATGAGCTCATACAACACATGTCCTTTGATCATTTGCAGCGTGCGAGTGCGCCAGTGATTGCCAACAACAAGCGggtgctgcagcagaagcGGGAGCGTCAGTATTCGGGACTCTTTCAGTGCGACAGCTGCACGCAGAGATTCAATATGAAGTCGGCCCTGGATCGACATGCTGCCGTGCATTCGGAGAAGGACAGGCCGCATGCCTGTCCGCACTGCTCCAAGCGCTTCAAACGGCCCCAGGACATGAACTGGCACATAAAGACGCACGAGAAGGAGAAGCCCaatgtgtgtgatgtgtgtggcAAGGCCTTTGCCCTGAAGTATGTCCTCACACAGCATAGGCTCAGCCATGAAGTATTGGAGAAGAACTTTCAATGCAACATTTGCGGTCGATCCTATCTGTTTGAAAAGTCTCTGCGGCTGCATCAACGCGTCCACACGGGCAATACCTACTACAAATGCGATCTGTGCCAGGAACGTTTCGTAACGCACATTAAGTTGAAAACTCATATGCAGAAGACGCATGCACATGCCTCTGAGACGCCTTCACCGGACTCCCTGGAGGATTTGATAAAAATTGTGATTTCTTAA
- Protein Sequence
- METCRTCAISMFSEMAHIRLEFVHWNLKISPNDGLPQKICSDCFTKFCSIYTFRLSCEEAQLKLSNIYDKIDASSLEDDNQEEEEADAAPKTETIIGTKSTTTTTTVSTETQPNTATATPIEFFVETIDSYIESPQPPYQDDNDDNDDDNATGCQELTISYACKYCFKPQESYQLQQLLLEHINASHDPDQPYNCPECEECFQDAASRTVHMKSCHVEKQFKCEVCGKKYSDRHNLRHHIEKYHSETDFECTMCEKRFFTRKSLTYHMKWHNPERQLKCRQTGCERLFINQRHLKCHEATHTGASARKSEHCGFCGKTFIHLKTLRWHIYRQHGGEKPYKCANCTEVFASYAEKRIHMLERHRENLTPIERSECMLCRQPFGTEHELIQHMSFDHLQRASAPVIANNKRVLQQKRERQYSGLFQCDSCTQRFNMKSALDRHAAVHSEKDRPHACPHCSKRFKRPQDMNWHIKTHEKEKPNVCDVCGKAFALKYVLTQHRLSHEVLEKNFQCNICGRSYLFEKSLRLHQRVHTGNTYYKCDLCQERFVTHIKLKTHMQKTHAHASETPSPDSLEDLIKIVIS
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00473982;
- 90% Identity
- -
- 80% Identity
- -