Dsub013727.1
Basic Information
- Insect
- Drosophila subsilvestris
- Gene Symbol
- ZNF212
- Assembly
- GCA_035043285.1
- Location
- JAWNNB010001922.1:5056197-5059598[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 10 2.1 1.5e+02 3.2 2.9 1 20 98 117 98 118 0.93 2 10 0.0016 0.11 13.1 2.7 1 23 158 180 158 180 0.98 3 10 0.08 5.7 7.7 1.1 1 23 206 227 206 227 0.95 4 10 6.2e-05 0.0045 17.5 1.7 1 23 234 256 234 256 0.97 5 10 4.6e-05 0.0033 17.9 0.8 1 23 280 302 280 302 0.98 6 10 3.1e-06 0.00023 21.6 0.4 1 23 308 330 308 330 0.97 7 10 8.8e-06 0.00064 20.2 2.2 1 23 336 358 336 358 0.98 8 10 7.4e-06 0.00053 20.4 1.2 1 23 364 386 364 386 0.98 9 10 4.3e-06 0.00031 21.2 0.4 1 23 390 412 390 412 0.98 10 10 9.2e-05 0.0066 17.0 0.8 2 23 443 465 442 465 0.95
Sequence Information
- Coding Sequence
- ATGTCCTCCATCAAGCGTGGTCAACCAGCTACCTCCATGCACGTGGAAGACAATAATGCCCAGGAGTCCGTGCTATATTGCAATATTTGTAGAAATTTATACGAGAACGAAGAGGCATACGAGGAGGACCATCATAGGGGCAGCTGCCTCAACGGCAGCGGCATGGAATGCATAGACGAGATTGATTTGGTTGAGGAGGAGGAAATAGTGGAGGCAGATGTGCCACTCTGGGACGTGAtagatgacgatgacgatgcaGCACCCCAGCAAGTCGATGCAGAGTCGGAACGTTACTTTTGCTTTGATTGCCACATCATATACGACAGCCACAGCAGTGCCGAAAACCATGTGTGCCCACCAGAAGGGGCTAGCAATGGAGCCAGCCAAAGGGCGACCATACCCAAGCAACCCGTCCGGCGCAAAGCTCCTGGAGCCGGAGCAACGGCAGGCATCAACGGAGATAGCCCCAAATTTACTTGCAAAATTTGCAACACCATTTTCAACACTGAAAAGAGTCTCAAGTTCCATAAGCGCATACACGACGAGCGCAAGCCCAAGCGAATTAAGGATGCCCTTCCTGTGGGCGCCCATCAGGAATATAGCGAGCTGGATCTGTTCTTCTGCGAGATCTGCCAAAGAGAGTTTGATTACGCCCTCAAGACGATTCACCAGAAGATGCACGTTGAGGCCCCGAGCAAGTTTGCGTGCGGCACTTGCAATCGCCGATTTGAGAACTCCACCAACTACCGGATGCATCTGAAGATGCATGAGAAGAAACAAGCGGAGCCctccgcatcattgtcgagaAAAGGGCCCGTGGACAAAAGTAAAGCACAATTTCCATGCCAGTACTGCGATAAGGTATTCTACCGCCCATTCGAGAAGGTCAAACACGAACGTGTTCACACAGGAGAGAAGCCCTACGCCTGCGAGGCGTGCGGCAAAACGTTTCGCGTCTCGTACTCTCTCACCCTGCACCTGCGCTCCCACACAGACATTCGCCCCTACGTGTGCACTGTCTGCAACAAGCGCTTTAAATTGCAGTCAAATTACGCTCATCACCTGCTCATCCATGGCGCGGAGCGTCTGTTTTCGTGTGATATATGCTCCAAGTCCTTCCGCACATCGGTGCAGTTGAACGGTCATAAGAACTCGCACACCAAGCCATTCGAGTGTGAGATTTGCAATCGTCCCTTTTCCACGATGTATGGCGTCAACAATCACATGAAGACCCACAAGAATGATAAAGGCAGCAAAGCTGCAACTGTGATTGTTTCGGCTGATAAGGAAGACGACTCTGTCAAGATTCTAGCTGGTGGCAAATGCTCCTGCAGTGAATGCGGGGCAGAGTACTCGCGCCTTTATGCGCTGCGGCAGCACCTTAAATCGGCTCACGGCAAGGCATTGGGTGCTAAGGCAAAGAAGAATGAGCAATCTTCCAGTAAGGAGTTGCATGTGGCCGAGTCGGACGACTCTGAGGCAGCCATacgcaaagcagcagcagaggcggATGCTGCCTACATGAATGCGGTGGTGAACGATGTGGACGTCAGTGGTAGCGTGCCCACCTACCAGGAGGCTGTTGAGTTCGATGTGGACAACTTCAACGGCGAGGAAATCATCAGTGATTGGCTGAAATAG
- Protein Sequence
- MSSIKRGQPATSMHVEDNNAQESVLYCNICRNLYENEEAYEEDHHRGSCLNGSGMECIDEIDLVEEEEIVEADVPLWDVIDDDDDAAPQQVDAESERYFCFDCHIIYDSHSSAENHVCPPEGASNGASQRATIPKQPVRRKAPGAGATAGINGDSPKFTCKICNTIFNTEKSLKFHKRIHDERKPKRIKDALPVGAHQEYSELDLFFCEICQREFDYALKTIHQKMHVEAPSKFACGTCNRRFENSTNYRMHLKMHEKKQAEPSASLSRKGPVDKSKAQFPCQYCDKVFYRPFEKVKHERVHTGEKPYACEACGKTFRVSYSLTLHLRSHTDIRPYVCTVCNKRFKLQSNYAHHLLIHGAERLFSCDICSKSFRTSVQLNGHKNSHTKPFECEICNRPFSTMYGVNNHMKTHKNDKGSKAATVIVSADKEDDSVKILAGGKCSCSECGAEYSRLYALRQHLKSAHGKALGAKAKKNEQSSSKELHVAESDDSEAAIRKAAAEADAAYMNAVVNDVDVSGSVPTYQEAVEFDVDNFNGEEIISDWLK
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00601212;
- 90% Identity
- iTF_00564107;
- 80% Identity
- -