Basic Information

Insect: Drosophila subpulchrella
Gene Symbol: ush_1
Assembly: GCA_014743375.2
Location: NC:25471723-25547089[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.0064 0.37 11.1 0.0 1 20 213 232 213 234 0.90

2 9 0.0017 0.097 12.9 0.7 3 23 285 305 283 305 0.97

3 9 0.11 6.1 7.2 2.4 2 21 347 366 347 367 0.92

4 9 0.18 10 6.5 2.2 2 21 736 755 735 756 0.93

5 9 0.0089 0.51 10.6 0.0 3 21 808 826 806 827 0.91

6 9 0.0064 0.37 11.1 0.0 2 23 892 913 891 913 0.98

7 9 0.0026 0.15 12.3 1.2 1 23 919 941 919 941 0.99

8 9 0.00068 0.039 14.1 0.8 1 23 992 1015 992 1015 0.96

9 9 1.5 87 3.6 0.5 2 20 1130 1148 1129 1150 0.89

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.0064	0.37	11.1	0.0	1	20	213	232	213	234	0.90
2	9	0.0017	0.097	12.9	0.7	3	23	285	305	283	305	0.97
3	9	0.11	6.1	7.2	2.4	2	21	347	366	347	367	0.92
4	9	0.18	10	6.5	2.2	2	21	736	755	735	756	0.93
5	9	0.0089	0.51	10.6	0.0	3	21	808	826	806	827	0.91
6	9	0.0064	0.37	11.1	0.0	2	23	892	913	891	913	0.98
7	9	0.0026	0.15	12.3	1.2	1	23	919	941	919	941	0.99
8	9	0.00068	0.039	14.1	0.8	1	23	992	1015	992	1015	0.96
9	9	1.5	87	3.6	0.5	2	20	1130	1148	1129	1150	0.89

Sequence Information

Coding Sequence: ATGTCACGACGCAAACAGTCCAACCCCAAGCCGTTGAATAAAGGTGATTGTTCCGATACCACAGAAGAGATGACCGTCGACAGCAGAGATTCCAAAGATCTGGCAGCTCAGGAGATGGGCGAAGAGAAGCAGCAGCAAATGGAGGATCAACTAGAGGATCAGATGGAGGATTCCAGAGACCCCCAGGagaacaacaataacaatattGATGACGACGATGAAGATGGTGCCTTCGAGCAGCCAGAAGAGACTAATCCCGAGCAGGATCTGGACTTGGGAGAGACAGAGATGGAACAGGATCACGATCTTCAGCCGGAGGAGCAGATTGAACTGCCTGCCAACAGTCCCAGCACTCCGCCCAGGAGTCCCAGCTCGCCGCAGTTGATTCCCAAGCTGGAACAGCCCGCCACGCCGCCCTCGGAGGCGGAACCCTCTCCGTGTCCCTCGCCCTGTCCCCCTACGCCCACGCCCAAGTTCCCCAAGGTGCGTCTGAATGCACTCCTGGCCTCGGATCCTGCTCTCAAGCCGGATGCCAAGGAGCTGACGCTGCCGGACTCACGGCTGCTGGCCCCTCCGCCGCTCGTCAAGCCGGAAACCCAAGCCCAACCGGAGGAACCCCATCTAAAGCCAGCCAGATTCATGTGCCTGCCCTGCGGAATCGCCTTTAGTTCGCCCTCAACGCTAGAAGCCCATCAGGCCTACTATTGCTCTCATAGGATTAAGGAGACGGAAGAGGCGGGCAGTGATAAATCTGGAGCAGGAGGATCTGCAGCCACGAGTGGCGAGGTGGGTTTATCCGGAGGCTCTACCGAGCCACCAGCCAAAATGGCCAGGACAGGAAAGCAATACGGCTGCTCCCAGTGCTCCTACAGTGCGGACAAGAAGGTGTCCCTAAATCGCCACATGCGGATGCACCAGACCTCGCCGGCGGCTCCCACACTGGCCAGTTTGCCAAGTCTCCTCCAGAACGGAATACCACCGCCGGGTGTTACACCAAGTTCACTGGAGGATAGCTCTAGTCAACAGCAAACAGATCGCTACTGCAGCCACTGTGATATCCGGTTCAACAACATCAAGACCTATCGGGCGCACAAGCAGCACTACTGCAGTTCCCGGCGACCGGAGGGACAGCTCACGCCCAAACCAGATGCATCTCCGGGTGCGGGATCAGTAGGACCCGGTTCCTCGGGACCCGGAGGCTCTGGAGGAGTGTCTGCCCAGGCAGCTGCGCCCGGAAAGCTCAGTCCACAGGCCAGGAACAAGACCCCAACTCCGGCGATGGTCGCTGTGGCGGctgcagcggcggcggcagctgCCTCCCTCCAGGCCACGCCCCATTCGCACCCACCCTTCCTGGCACTGCCCACGCACCCGATCATCATTGTGCCCTGCTCGCTAATTCGGGCGGCCAGCTTTATTCCAGGACCACTGCCCACTCCGAACTCGGGAATTGTGAATCCAGAGACCACCTGCTTCACCGTGGACAATGGAACGATCAAGCCCCTGGCCACTGCCCTCATCGGTGCTTCTCTGGAGCCCGAACGTCCCTCAGCTCCCTCTTCGGCTGCTGAGGCCACAGAGCCCAAGAGCAGTCCACCGGAACCCAAGCGAAAGGAGGCAGGAGGAAGTCGCGAATCTGCGCCTTTGGATCTCTCGCTGCGTCGATCGCCCATCTCCCTTAATTCCCTGGCCTTGCGACAGCGCCAACTGCGCAATGCACTGCTCGATGTGGAGGAGGTCCTTCTCGCCGGCGGAGGAGTGAGTGTCAAGGACAACGCGGAGACTCCGCGAGGAGGCGGAAGTGTAACGCCCGAGCAGATTGTGTGCGCCCCCTCCCTGCCGAGCAGTCCTTCGATGAGTCCCTCGCCCAAGCGACGAGCCATTAGTCCACGCAGTTCCGGGGCTGGCAGTGCCTCCTCCATGTCGCCACCTGGTCTCAATGTGGCTGTGCCCCACATGCTCGACATGCGCTCCATGCTGCCGGCGGACTTTGGGCTCTCCGAATCGCTGCTGGCCAAAACCAATCCGGAACTGGCTCTCAAACTGGCGGCAGCAGCTGCAGCGGCTGCTGTCGCGGGCAGCAGTGGGGCAGCAGCCTTTCCGCCATCACCCCTTCCTGCCCAGACAAGTGGCGGAAATCCTGGCGGCGGAGGAGCAGCAGGTGGCGCCCAACAGCCGCAAATTTACGTGAAGAAGGGCGTGTCCAAGTGCATGGAGTGCAATATTGTGTTTTGCAAGTACGAGAACTATTTGGCCCACAAGCAGCATTATTGCTCGGCTCGGAGTCAGGAAGGAACGGGTGAAGTGGATGTCAAGTCGGCCGTTTCACCATCCAATCCAGGAGCTGGAGGACTGGGAGCTGGCGGGTCAGAGGCAGCTTCGTCAGTCGAAACCACTCCGGTGGCCTATCAACAGCTGATCTGCGCCGCCTGTGGCATCAAGTACACCTCCCTGGACAACCTGCGGGCCCATCAGAACTACTACTGCCCCAAGGGAGGAGCAGCTGCTGCCCCCGCCGCGACGCCCTCAGATCCTGGGCAACTGGCCCTGGTCAAGGAGAAGTGCGGAAAGTGCAAGACCCTGCACGAGATTGGGCTACCCTGTCCACCGCCAGTCACAAGTCCCCTCGCCGCACCCACCACCAATTCCCAGCCCGCCTCCAACAGCCTGAACAAGTGTCCTGTGTGCGGAGTAGTCAGTCCCACGGCGGCGATGGCCAAGAAGCACATGGAGATGCACGGCACGGTGAAGGCCTACCGCTGCAGCATCTGCCAGTACAAGGGGAACACCCTTCGCGGCATGCGCACTCACATTCGCACCCATTTCGACAAGAAGACCAGCGATGTGAACGAGGAGCACTACATGACCTGCATCTTCGAGGAGGAGGGTTCCACGCTGACCCAAGAGCTGTCTCCTGCACCTGGAGCACCTGCAACAGTTGCCCACGATTCCATGGACCATCCCTCACAGATGTTCAACTGCGATTATTGCAACTATGCCTCCACCTACAAGGGCAATGTGCTGCGCCACATGAAGCTGCTGCATCCGCATGTTCCCATCAACTCACCTTCGATTTCCCCCGACACCAGAGATCAGGACGTGACCTCGAACCCCACTCCCAACCAACACTCGAATTCCGATGGTTCAAACGGTGAGGCAGCCAGCTTCCACATCAAGTCGGAGCCCCTGGATAATCCGCCGACGCTGAGCCTGGTGCACGAGAACAACAACTCGCCGATTTCAACGCCCCACATCAAGGCTGAGCCAATGGAGATCGGTACGGATGTGGCGCCTGGTGGGCTGGTTCCGCCGATGGCTTCTCCTCTGGGAAACAGCAGCGTGGCCGCCACAGCAGCTGCCGTTGCCGCCGCCGAGGTGATGAAGAAGTACTGCTCGACCTGCGACATATCCTTCCAATACGTGAAGACATACCTGGCCCACAAGCAGTTCTACTGCAAGAACAAGCCGATTCGCCCGGAGGCGAGCGATAGCCCCAGTCCGAATCACCTGGGCGGGGGCGTGGCCGTGGGCTTGGGCATCGGCGGGATCGTGGCTGGACATGGCCAGCAGAAGAACAAGGAGAACCTGCAGGAGGCGGCCATTTGA
Protein Sequence: MSRRKQSNPKPLNKGDCSDTTEEMTVDSRDSKDLAAQEMGEEKQQQMEDQLEDQMEDSRDPQENNNNNIDDDDEDGAFEQPEETNPEQDLDLGETEMEQDHDLQPEEQIELPANSPSTPPRSPSSPQLIPKLEQPATPPSEAEPSPCPSPCPPTPTPKFPKVRLNALLASDPALKPDAKELTLPDSRLLAPPPLVKPETQAQPEEPHLKPARFMCLPCGIAFSSPSTLEAHQAYYCSHRIKETEEAGSDKSGAGGSAATSGEVGLSGGSTEPPAKMARTGKQYGCSQCSYSADKKVSLNRHMRMHQTSPAAPTLASLPSLLQNGIPPPGVTPSSLEDSSSQQQTDRYCSHCDIRFNNIKTYRAHKQHYCSSRRPEGQLTPKPDASPGAGSVGPGSSGPGGSGGVSAQAAAPGKLSPQARNKTPTPAMVAVAAAAAAAAASLQATPHSHPPFLALPTHPIIIVPCSLIRAASFIPGPLPTPNSGIVNPETTCFTVDNGTIKPLATALIGASLEPERPSAPSSAAEATEPKSSPPEPKRKEAGGSRESAPLDLSLRRSPISLNSLALRQRQLRNALLDVEEVLLAGGGVSVKDNAETPRGGGSVTPEQIVCAPSLPSSPSMSPSPKRRAISPRSSGAGSASSMSPPGLNVAVPHMLDMRSMLPADFGLSESLLAKTNPELALKLAAAAAAAAVAGSSGAAAFPPSPLPAQTSGGNPGGGGAAGGAQQPQIYVKKGVSKCMECNIVFCKYENYLAHKQHYCSARSQEGTGEVDVKSAVSPSNPGAGGLGAGGSEAASSVETTPVAYQQLICAACGIKYTSLDNLRAHQNYYCPKGGAAAAPAATPSDPGQLALVKEKCGKCKTLHEIGLPCPPPVTSPLAAPTTNSQPASNSLNKCPVCGVVSPTAAMAKKHMEMHGTVKAYRCSICQYKGNTLRGMRTHIRTHFDKKTSDVNEEHYMTCIFEEEGSTLTQELSPAPGAPATVAHDSMDHPSQMFNCDYCNYASTYKGNVLRHMKLLHPHVPINSPSISPDTRDQDVTSNPTPNQHSNSDGSNGEAASFHIKSEPLDNPPTLSLVHENNNSPISTPHIKAEPMEIGTDVAPGGLVPPMASPLGNSSVAATAAAVAAAEVMKKYCSTCDISFQYVKTYLAHKQFYCKNKPIRPEASDSPSPNHLGGGVAVGLGIGGIVAGHGQQKNKENLQEAAI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00505683;
90% Identity: iTF_00486855;
80% Identity: -