Dsup010976.1
Basic Information
- Insect
- Drosophila subpulchrella
- Gene Symbol
- HINFP
- Assembly
- GCA_014743375.2
- Location
- NC:11814744-11818859[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 10 0.22 13 6.2 0.1 3 23 27 49 25 49 0.90 2 10 8 4.6e+02 1.3 3.5 1 23 64 88 64 88 0.91 3 10 0.014 0.79 10.0 0.1 1 23 128 152 128 152 0.96 4 10 1.2 68 3.9 3.1 3 23 172 194 170 194 0.94 5 10 0.0011 0.064 13.5 1.3 3 22 202 221 201 221 0.95 6 10 0.00023 0.013 15.6 2.0 1 23 230 252 230 252 0.97 7 10 5.1e-06 0.00029 20.8 3.2 1 23 256 279 256 279 0.98 8 10 2.5e-05 0.0014 18.7 0.6 2 23 286 308 285 308 0.96 9 10 0.16 9.5 6.6 4.6 1 23 313 338 313 338 0.91 10 10 0.35 20 5.6 4.7 1 23 345 368 345 368 0.95
Sequence Information
- Coding Sequence
- ATGTTGAGACCCCAGCCATCGATGCCATTGCCACAGCCGCCCGGAAAGCGCAAAAAGCCCGCGGAGCTGCAGTTATCGTGCGGATGGCGAGGTTGCCAGGAGATTTGCACGGGCGAATGGAACCTCAATTCCCACATTGCCGAGCATCTGGAGCAGTATGCCCGGGACCAGGACAGTGGGGAGGATCAGCATCAGTGCACGTGGAACTCCTGCGACTTTTGCACCGAAGACCTGGTGGAATTCGAACGACATTCGTACTATCACGGCTACTACCTGCACCTTCTGCTGCAGGGCAAACTGGAGTGCGACCTGCATCCGGAAATCCCTGCCTGCACTGCTCCCGCCCGCCTCGTGGACAAGCTACCCATTCTTGGCCAGAATTTCCGCTGCGGCTGGACGGATTGCGAGCGCGAGTTCGTCTCGATTGTTGAGTTCCAAGATCATATAGTAAAGCACGCCCTGTTCGAGTACGATATACAGAAGACGCCGGAGGACGAGCGGCCCAAGACCATGTGCAACTGGACCATGTGCCACAAGCACATGGGCAACAAGTACCGCCTCATCGAGCACATCAGCACGCATTCGAACAAGAAGCTGGTGGCCTGCTTCCACTGCGGCGAGCTGTTCCGCACCAAGACCACGCTCTTCGATCACCTGAGACGCCAGCCGGAGAACAACACGAACAGCTTCCAGTGCGCGCAGTGCTTCAAGTTCTTTGCCACCAAGAAGCTACTGAAGAGCCACGTGGTGCGGCATGTAAATTGCTACAAGTGCACCATGTGCGACATGACCTGCAGCTCGGCCAGTTCGCTGACCACCCACATCCGGTACCGCCACCTCAAGGATAAACCCCTGAAGTGCAGCGAGTGCGATACGCGCTGCGTCCGGGAATCGGATCTGGCCAAACACATCCAGATTGTCCACTCGAAGACGGTGCACCAGTGCGAGCATCCGGACTGCCATTACTCCGTGCGCACCTACACGCAGATGCGAAGGCACTTCCTGGAGGTGCACGGCAACAATCCCATTCTGTACGCCTGTCATTGCTGCGAGCGCTTCTTCAAGAGCGGCAAATCCCTATCCGCCCACCTGATCAAAAAGCACGGCTTTCGGCTGCCCTCTGGCCACAAGAGATTCACCTACCGGGTGGACGAGAACGGATTCTATCGCCTGGAGACGACGCGCATCGAGAGTTTGGAGGTGACGCAGCAAATACTATCGCCGCAGGTGAATGTCTCGCTAGAGGTAGACTTGAAACCGGGCACTGGCACATGTTACGAGATCGTGGATCCCACAAACACCGAATTCGAGCGCATCATCGTCTCGAATGATCCGCACGAGGCGCAGTTGATGGGCGAGGTGGTCATCTCGCTGCCAAGCCTAACGGAGGAGCTGTGA
- Protein Sequence
- MLRPQPSMPLPQPPGKRKKPAELQLSCGWRGCQEICTGEWNLNSHIAEHLEQYARDQDSGEDQHQCTWNSCDFCTEDLVEFERHSYYHGYYLHLLLQGKLECDLHPEIPACTAPARLVDKLPILGQNFRCGWTDCEREFVSIVEFQDHIVKHALFEYDIQKTPEDERPKTMCNWTMCHKHMGNKYRLIEHISTHSNKKLVACFHCGELFRTKTTLFDHLRRQPENNTNSFQCAQCFKFFATKKLLKSHVVRHVNCYKCTMCDMTCSSASSLTTHIRYRHLKDKPLKCSECDTRCVRESDLAKHIQIVHSKTVHQCEHPDCHYSVRTYTQMRRHFLEVHGNNPILYACHCCERFFKSGKSLSAHLIKKHGFRLPSGHKRFTYRVDENGFYRLETTRIESLEVTQQILSPQVNVSLEVDLKPGTGTCYEIVDPTNTEFERIIVSNDPHEAQLMGEVVISLPSLTEEL
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00565639;
- 90% Identity
- iTF_00605882;
- 80% Identity
- -