Dsup008189.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila subpulchrella
Gene Symbol
-
Assembly
GCA_014743375.2
Location
NC:9434555-9466699[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 8 0.063 3.6 8.0 1.9 1 23 1408 1430 1408 1431 0.95
2 8 0.0062 0.36 11.1 0.1 1 23 1436 1459 1436 1459 0.98
3 8 0.0024 0.14 12.4 2.6 1 23 1721 1744 1721 1744 0.95
4 8 0.00053 0.031 14.5 2.1 1 23 1752 1774 1752 1774 0.98
5 8 5.5e-05 0.0032 17.6 0.2 1 23 1781 1804 1781 1804 0.97
6 8 2e-05 0.0012 18.9 1.4 1 23 1810 1832 1810 1832 0.97
7 8 1.6e-06 9.3e-05 22.4 1.9 1 23 1837 1859 1837 1859 0.99
8 8 0.00035 0.02 15.0 2.4 1 23 1864 1886 1864 1886 0.99

Sequence Information

Coding Sequence
ATGAGTGCCAACCGAAGAAGACAGAGCAGTTTCTTCTGCGCGAAGACGGCAACAACCGAGGAGAAGACGGCAAAAAGAGTCAGTGCAAGAGCtgcagcaactgcaactgaAATTGCACCATGCAAAGAGCAGCTTTCTCTACCGACTGCTGATGAGGATTTACTGGAAATGCCTCGCATTTGCCGCTGCTGTTGCAAACGGGATTTGGAATTACTCGGCTTATTCGAGGCCAGCCAGCCAACATTGGCCAACACATCAGCATCGAACAAATACAAATCATCGGGAACATTAGCAAAAACATGTGCGACAGAAGCAGAAGCAGAAACCGAAACTCCAGAGACATTGTCCGCAAATCCAGTAAATCCCGGCACTAAAGCTACATCATCTCCATCAGAAGCAGCTACAGCTACAGCAACGGCTACAGcaatgtccgcattttcaacCACACCCTCCTCCACATCTCCCATGAGGCGTCGCACCACTGCTaccaacaccaccaccaccaccaccacaacacCCACTGCACCGCCAGCCCCTCGTGGACGGAGCAGCGATAATGCCGTCGACTACACCCTCAGCGGAGCCCACAGCAGCATGGACATTGTCCTCGAGGAGATGACCATTTGGATGCTCAATATAAATCGCGACGATGGACTGCCGCAAGAAATCTGCCGGCAGTGCATGGCCCAGTTTTTGATGCTGGCCAAGTTCCGGCGGAAATGTGTACGGATGCAACAGCGCCTGCAGGACTTTGCCCAGGAGATATCCGACCGCCAGACGGCCAGACAAGCGAAGCGTCAGCAAAAAGTCCAAAAGAAGAGTCAGAGTCAGGACAGTGAGGCCttcacatccacatccacatccacatcgaCATTCAGCGGGGAACCCCTGACCGTGCCCTTGCGAAAGCGCCGTATGGTATCGGAATCCGATTCCGGAGAATCGGCTTCAGCAGCTGTTGCAGTGAAGCAGGTGCGCACGGAATCGGAGGATTTACCGCCACCCAAGCCGAGTCCAGTGCCACTTCGTCTGCGCAAATATCGCACCTTCTCCATTGGCTGTGAAATGGAGCGTCCCTCCATCGATGCCAGCAGCATGCCCTGGAAGACGAAGGCGGCCCGCAAGCAACTTTCGGAGACCTGGTCATCGTCCCGCTGCTCCCCGGAGCTCCTCATCCCCTCGCCATCGCGCCAacgcagcagcaccagcagcagtgAGCACACAAGCGACCTGTCCGTGGGTCCATGTTGTGGCTTCGAGAGCGACAGCAATCCCTCCTCCTCAACCGCCTTCAGTGCCGCACCGAACATCGGTGTTGTGGTGAGGTCCCCCCCGAAGGCAAAACCCTCGTCGCCAGTCAATGATTTATTGCCCCGCAGGGGTCGGCGTCCGAGGAATGCGCCAATATACCATCCCCCCAAACGACAACGACGATCGCTGGTTAGAAGGGAGCCGTTGAAGCGAAAAGTTATGACAGAACAAGTTAACACAGAGAAAAGAAAGTCTGATCAAAACGATATTTATCCGCCGGAACCGAAGGTGGAGAACTTGGCCCCATCCTGCGATGAGGCCATCGACAGCACATCCGATGCACCAAAGGAAGGACCATCGAATGTGGTCCAAGAGGAATGTAATCCAATTAATTCAAACAAAGTTTGTGGTGATATAAGCCAGGGTGAAAAGGAGAAGGAAATCACATCGAATGGTTTGATAGAGAGTTCCAACCAGGTGCAAGCTGTAGAAGAAGATAAAGCGCCCAATGGCGTTGAGGAACTGGTTCAAGTCGAGGAAGAACTACCTAAAGCTGATCTAAATGTCCTCAGACATCCTTGTACTGATGAAAATGATGAAATTACTGGAACCTACCGGGAGTTACTGGAACAGTTCGAAGCCACCACCGCTCCCAATGAATATGCTTCAGATGATCTCCCCATTAAAGAGGAAATCCAATCCATTTTGAATGTCATCAAAGCTGAAGCCGATCTAGTGCAATCCGGGGAACTGACCTCATCCACGGAACCCAGTGAATTGCAACCGCAAATTGTTGAGCAGCTGGTAACTGTGGAGCAGCAAGCATTTGCTATGGAACAGCAGGAATCCATGGAGCAACCGGTGAGATCTGTAGACCAACCTGACTCAGTGGAGCAGCCGGAGATCATTGTGAGCATACCGCTGGAGGCCCTTGACGAGAATCTACAGCGTCGCCTTTGCTTGGATCCCGAAACCGAGGAGTCGCCGAATCGCGAATCTGCCACGCCCAAGGATCTGCCCATGCAGCCCGATGACGTCAATAACAATGAGAACGATGAAAATTTTTGCCAGAGTGCTACAGCAGATAGCTTCAATTCTGCTGTGGCACTCAGAACCGATCAAATTGAAGCATTACCACCGGGGGAAACGGATGAGACGGACGCGGATGAGGTGCAGGTGGTGCGATCTGGACCCACGCCCATGGATTTTATGGCCGAGTTTGCCAAACACTGTGCAAACGGCATTGAGCAGCTGAAGGCCACCACTCCAGTGGCATCGCCCACGCCCTCGGACCTGCTGCCCCTTAATGATCTGGATGCTAAGCAGAAACTAGAGGTGGAGATGAACGACGTGGAGAACACTCTTAATGGCATCCTTAACGAGATGCAGGACCAGCACATGTACACACCGACTTGTGCCCACATTGATGAGTTTCTCACTCCCGCCGATTATGCTCCAATGACGGAGCAAGAGACGTCCGTTTCATCGCCGCCCAATCCTTTCGAACAGAGTCCACGTGCCGAACCGGAGGCCAAACCCAATGCCTCCGATGATCCCTTCGATAACAGCAACTTTAGCAGCGAACTGATTGGCTTCCAGAACGATATTCCCTGCTTTGAGAATATTGAAACCACTACAGAACAGGGACAGAACCTGCATTTAGAGCTTACTCAGTTCCTAAGGGATCTTCAGCCGGCACAACCAAATCAGCAGCCCCAGGAGCAAGGCGCCAAGACCCAAGTTGAGACACAGGAGACTGTCCAGATGGAAGTCCAAGCCTCCAACCTCCAGATGCAACCTGATATTCAGGCTCAAAATGAGTCTGCCGATCCTTCTCCGAACGAATCTCCCATATCATCACCTCAAGTCGGGTCCCAAATTGAAATACAGATGGAACCTGAAATTGAGACTCAGCTGCAACACGAAATTCTGACAGTGCAGACTCCACAACAAAATCAGCCTGAAGTACAATCTCATGACCAATCTCAGATCCCACCGCAGATAGTGCCTCAGATTCAAGTCCAAAACCATCATGAGCAAACATTACAAATCGTGCCGCATGGCCAGCAACAAGTGGTTGCTCAAATGCATCCCCAGATGCAGCTTCAGTCCCAGATAGTGCCCCATGTCCAGACGCGGGGCACTACGACGACAGTCACCTACGAGCAGATCTATCAGCAGCACATTGTCCAGCAGACGGTGCAGCAATCCTCCAACAAGATGCAGGTCATCTCGCTGCCCTCGGGTGGATCGGAAAGAAGGCAGTGGAAGACACAGCAgtcgcaacagcagcagcagctccagTGGTCAACGGTGGGCGGACTGGAGGCCATTAAGAGTGCCCCCGTCGATAGTGTTTCACCCACAACTACAACATACTACATCAGTGCCGGCGATCTGTATCCGCAGCAGGGTGAAACTTACACTATGCTGCAGCCGGCACCCAAAGACAGCTACATGATCGAGCACGTGaatcaccaccaccaccagcagcaacatcgtcagcagcagcatcaccaGCAGCAAATTCAACTGGCCCAACAGCAACATCACCAGGCGCAGCAACAACCGATTATGATACTGATTCAGCAACAAGATGTTCAGAAACCGGTGGCCTCAGCCAGCAATCCTCGACAGGCACCAATGCACGCCTACAGAAACGATATCCATCAACTCCAGAACACGCAacaccaacaggtacggcagCAATATTACCGTCAGCAGCAATATCAGCCGCAACAGGGaacgcagcagcaacagtcgCAACAAAGTCGAGTCGTACAAAGCCATCCAGTATTGGGAATGCCGGGAGCCACTTCTATTTCCACCAAAGTGACCCCTATTCCCGCCACAACGCCCAAGGGCAGGGCCCTGACGCTCAAGTGCCGCTTCTGCCATAACGGACCGCGATTCTCCAGCAGCCTGGAGTACAGCCGACATATCATCGATCTGCATCCGGCGGTGGCGCCATTCAACTGTCCACACTGTCCTCTCGCATTTGCCGGCCGGACCAAGCGATCGCAGCACATCCTTAGCCACCATGTGGTGCAGCAGTATCAATGCGGCCAGTGCTCTCAGGTGTTCCCGGCCCAGAAGGCTCTGGACATTCACATCCAGCGTTTCCACATGCAACTGAAGACAGAATCTCAGGGGGCTGTGAGTGTGGAGGACGTTCAGCTGGAGATCACCGGAGATCGGAGGCGGGGTAGACCGTATAAACCAAGgttgcagcaacagcagcatcaGCTGCAACCACAGCATCAGCTACAAGTactacagcagcagcagcagcagcaacaacaacagcaacaacaacaacaacatcaggagcagcagcaactgcagcagttacagccgcagcagcaacaacagcattCGTTGCAAGTGCAGCATCCACAGCAACAGCCGATAATGCAGCCGCAATCGCCCCATCCATCAACAATGGAAATCCAGGCCAGCCCAACAACGCCACGAAAGATTCTCTGCTGTCCCGATTGCGAAGACTGCACTTCCGGCCACAACCACGGCCACAGCCACGGCCACGAGCAGTGCGAGGAGCAGGCGGTACTGCAGGCTCCGACAACGGTCCTCACTCCGCCCTCGACCATAGTCTCGGCTCCGTCGCCGCAGCCCATGATGTACTCGCAGCACATAACAATGCCGTCACCGGAACAATCCGAGCCAGATTCCACGACCACGTTGCGACAGTACCGCAAGCGTGGCGTGATCGTTGGGCCACAGGGTCCGCTGCATTTGGCCACACCAGTGGCCTCACCCTCGCCGTCGTCGTCACCCTCCTCGTCGACGGTGGACCATGCGCCGCCAGCCTCCCCGGCGCCGCCCGCTTCTCCGGCTCCGCCTCCATCACCAGCCCCACCCACGGTGCAGATGAACGAGTTGCGAGCGTGCCACCAGTGTCTGTACTGCGAGGAGCGATTCACCAATGAGATTGCCCTGAAGAAGCACCATCAGCTGGCGCACGGAGCCCAGACAACGATGCCTTTCGTGTGCACCATCTGCAAGCGTGGATATCGCATGCGAACGGCTCTGCACCGACACATGGAGTCGCACGACGTGGAGGGACGACCATATGAGTGCAACATTTGTCGCGTGCGTTTCCCACGACCATCGCAGCTGACGCTGCACAAGATCACGGTGCACTTACTCTCGAAGCCGCATACCTGCGACGAGTGCGGCAAACAGTTTGGGACGGAGAGTGCCCTGAAGACGCACATCAAGTTCCATGGTGAGCTCGGTTACCAGTGCGACGGGTGCGATCGGACATTCGAGTATCTGAAAGAATTGCGCAAGCATCGACGCACCCACAGCGAGATGTTTTACAAATGCAAGTTTTGCCCAAGCTCCTTTGTGCGATTCACGGGTTATCGGGCCCACATGAAAACCCATTTGCCACTGGGCGTATTTATCACCGAGGAAGTCGCATCAAAGTCACCCAGCAACAATAATAGCACCACTAGCAATGATAAGGTGCTGGATCCATCCACAACACCCATCGAGGAGACCCCTTTGACGCCGATGAGCAGCGGTGGACACGTGTACAACAGCCCCGATGAATACCCCAATTCGGTGGAAAGCTGTGCTGGCAACAGCCTGGCTTTGGATACAATTGCCACGACGCCATAA
Protein Sequence
MSANRRRQSSFFCAKTATTEEKTAKRVSARAAATATEIAPCKEQLSLPTADEDLLEMPRICRCCCKRDLELLGLFEASQPTLANTSASNKYKSSGTLAKTCATEAEAETETPETLSANPVNPGTKATSSPSEAATATATATAMSAFSTTPSSTSPMRRRTTATNTTTTTTTTPTAPPAPRGRSSDNAVDYTLSGAHSSMDIVLEEMTIWMLNINRDDGLPQEICRQCMAQFLMLAKFRRKCVRMQQRLQDFAQEISDRQTARQAKRQQKVQKKSQSQDSEAFTSTSTSTSTFSGEPLTVPLRKRRMVSESDSGESASAAVAVKQVRTESEDLPPPKPSPVPLRLRKYRTFSIGCEMERPSIDASSMPWKTKAARKQLSETWSSSRCSPELLIPSPSRQRSSTSSSEHTSDLSVGPCCGFESDSNPSSSTAFSAAPNIGVVVRSPPKAKPSSPVNDLLPRRGRRPRNAPIYHPPKRQRRSLVRREPLKRKVMTEQVNTEKRKSDQNDIYPPEPKVENLAPSCDEAIDSTSDAPKEGPSNVVQEECNPINSNKVCGDISQGEKEKEITSNGLIESSNQVQAVEEDKAPNGVEELVQVEEELPKADLNVLRHPCTDENDEITGTYRELLEQFEATTAPNEYASDDLPIKEEIQSILNVIKAEADLVQSGELTSSTEPSELQPQIVEQLVTVEQQAFAMEQQESMEQPVRSVDQPDSVEQPEIIVSIPLEALDENLQRRLCLDPETEESPNRESATPKDLPMQPDDVNNNENDENFCQSATADSFNSAVALRTDQIEALPPGETDETDADEVQVVRSGPTPMDFMAEFAKHCANGIEQLKATTPVASPTPSDLLPLNDLDAKQKLEVEMNDVENTLNGILNEMQDQHMYTPTCAHIDEFLTPADYAPMTEQETSVSSPPNPFEQSPRAEPEAKPNASDDPFDNSNFSSELIGFQNDIPCFENIETTTEQGQNLHLELTQFLRDLQPAQPNQQPQEQGAKTQVETQETVQMEVQASNLQMQPDIQAQNESADPSPNESPISSPQVGSQIEIQMEPEIETQLQHEILTVQTPQQNQPEVQSHDQSQIPPQIVPQIQVQNHHEQTLQIVPHGQQQVVAQMHPQMQLQSQIVPHVQTRGTTTTVTYEQIYQQHIVQQTVQQSSNKMQVISLPSGGSERRQWKTQQSQQQQQLQWSTVGGLEAIKSAPVDSVSPTTTTYYISAGDLYPQQGETYTMLQPAPKDSYMIEHVNHHHHQQQHRQQQHHQQQIQLAQQQHHQAQQQPIMILIQQQDVQKPVASASNPRQAPMHAYRNDIHQLQNTQHQQVRQQYYRQQQYQPQQGTQQQQSQQSRVVQSHPVLGMPGATSISTKVTPIPATTPKGRALTLKCRFCHNGPRFSSSLEYSRHIIDLHPAVAPFNCPHCPLAFAGRTKRSQHILSHHVVQQYQCGQCSQVFPAQKALDIHIQRFHMQLKTESQGAVSVEDVQLEITGDRRRGRPYKPRLQQQQHQLQPQHQLQVLQQQQQQQQQQQQQQQHQEQQQLQQLQPQQQQQHSLQVQHPQQQPIMQPQSPHPSTMEIQASPTTPRKILCCPDCEDCTSGHNHGHSHGHEQCEEQAVLQAPTTVLTPPSTIVSAPSPQPMMYSQHITMPSPEQSEPDSTTTLRQYRKRGVIVGPQGPLHLATPVASPSPSSSPSSSTVDHAPPASPAPPASPAPPPSPAPPTVQMNELRACHQCLYCEERFTNEIALKKHHQLAHGAQTTMPFVCTICKRGYRMRTALHRHMESHDVEGRPYECNICRVRFPRPSQLTLHKITVHLLSKPHTCDECGKQFGTESALKTHIKFHGELGYQCDGCDRTFEYLKELRKHRRTHSEMFYKCKFCPSSFVRFTGYRAHMKTHLPLGVFITEEVASKSPSNNNSTTSNDKVLDPSTTPIEETPLTPMSSGGHVYNSPDEYPNSVESCAGNSLALDTIATTP

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00605113;
90% Identity
iTF_00605113;
80% Identity
-