Basic Information

Insect: Drosophila subpulchrella
Gene Symbol: -
Assembly: GCA_014743375.2
Location: NC:6873962-6877550[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 1.2e-05 0.00069 19.7 0.3 2 23 204 225 203 225 0.96

2 6 0.00073 0.042 14.0 1.9 1 23 231 254 231 255 0.96

3 6 0.00015 0.0084 16.2 0.4 1 23 263 286 263 286 0.97

4 6 3.4e-08 1.9e-06 27.7 1.2 1 23 299 321 299 321 0.97

5 6 0.011 0.62 10.4 3.3 1 23 329 352 329 352 0.96

6 6 4.8e-06 0.00028 20.9 2.7 2 23 359 380 359 380 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	1.2e-05	0.00069	19.7	0.3	2	23	204	225	203	225	0.96
2	6	0.00073	0.042	14.0	1.9	1	23	231	254	231	255	0.96
3	6	0.00015	0.0084	16.2	0.4	1	23	263	286	263	286	0.97
4	6	3.4e-08	1.9e-06	27.7	1.2	1	23	299	321	299	321	0.97
5	6	0.011	0.62	10.4	3.3	1	23	329	352	329	352	0.96
6	6	4.8e-06	0.00028	20.9	2.7	2	23	359	380	359	380	0.98

Sequence Information

Coding Sequence: ATGTTTGAATCGATGCTGAACCAGTGCGCGAGTCGCATGGTCGCGGACTCCACTACCTTGGGAATGGATGGACGAGATGTGACCAAGACGATGATTTGCCGAGCCTGTCTGGTGCTGCTGGGGCCCCAGGATGCCTCCTACCATCTGGACAGCGAGGGGGACTTGGCTAGGAAATATTTCGGCTGCACTGGAGGCGATCCGGGGAACGTATTTCATCCGCAGGACGAGGATTTGCCACCCCAGTTGGTCCTGAAAAGCATCTGCGAATGCTGCTACCAACTGGTGCAAAAGTTTCACGACTTTCAACGCATGTGCGAAGAGTCCTCGCGCAACTTTGAGAAGCTGCTTCTAGACATCGACTTTGAATGCACTAAAAATCAGGATGATATCAACATGCCCGACTTGGATACCCCCtcggaaagtaatgaatccACTAATCAGGAAGCCCAAATGGACGCACCCTGCATCGAATCAACGGAAGAGATTGAGGAAGTATACATAATTGAAGACGAGGCGGTCAAGCAAGATCTTGGAATGGATATACTACCCATTTCGTCTATTAGAAAGTTGTTCAAAGGAAAGAGACGAAGAGGAGAAAGACTCACCCTCGAGTGCAACATATGCCGTCGAGGCTTCTACAAATCGTCGCTGCTGGAGGCCCATATGATGCAGCATGAAGGTCTGAAACCGTATACCTGCGTCCATTGTGCCAAGAGCTATGCGAGGGCCAATCTGCTAGACACGCACCTGCGGGAGATGCATCATAATACCTCCGCGAGGGTAACCTATCCCTGCCCAAACTGCAATAAAGTGTACACAGCTGATCGAAGTCTCAAATATCACTTAAAGAGGGCACACGAAAGGACTCATAGGCTAGAATCCCCCGACTCCCTGCACGTTTGCGAAGAGTGCGGAAAGTCCTTTGTGCGCAGGGCCCTTCTAACACGCCACAGAAGGATCCATGGAAGTGCGGAGGATCGGAAGTACTCCTGCGAATGCTGTGACCAGAGATTCTACACCAAGGAGAACATGGTAGATCATCTGCAGCGAAGACACGGGAACAAGAACCTACCCAGGTGCCGAAAGTGCGGTCGCATTTTCAGGAGCAGGTCAGCCCTCACCACTCATCTGAAAAAACACGAGTTGGCCGGCGAGTTAATGTAG
Protein Sequence: MFESMLNQCASRMVADSTTLGMDGRDVTKTMICRACLVLLGPQDASYHLDSEGDLARKYFGCTGGDPGNVFHPQDEDLPPQLVLKSICECCYQLVQKFHDFQRMCEESSRNFEKLLLDIDFECTKNQDDINMPDLDTPSESNESTNQEAQMDAPCIESTEEIEEVYIIEDEAVKQDLGMDILPISSIRKLFKGKRRRGERLTLECNICRRGFYKSSLLEAHMMQHEGLKPYTCVHCAKSYARANLLDTHLREMHHNTSARVTYPCPNCNKVYTADRSLKYHLKRAHERTHRLESPDSLHVCEECGKSFVRRALLTRHRRIHGSAEDRKYSCECCDQRFYTKENMVDHLQRRHGNKNLPRCRKCGRIFRSRSALTTHLKKHELAGELM

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00536993;
90% Identity: iTF_00605043;
80% Identity: -