Basic Information

Insect: Drosophila subpulchrella
Gene Symbol: -
Assembly: GCA_014743375.2
Location: NC:6771976-6776396[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 13 0.0073 0.42 10.9 0.3 2 23 32 53 31 53 0.96

2 13 0.0043 0.25 11.6 4.4 1 23 59 82 59 82 0.94

3 13 0.014 0.78 10.0 1.2 1 19 96 114 96 117 0.93

4 13 0.0095 0.55 10.5 4.1 2 22 133 153 132 153 0.91

5 13 0.33 19 5.7 2.0 2 23 398 420 397 420 0.94

6 13 0.013 0.76 10.1 0.3 1 23 445 467 445 467 0.97

7 13 0.0053 0.31 11.3 1.6 1 23 475 499 475 499 0.95

8 13 0.12 6.8 7.1 2.4 2 23 504 526 503 526 0.95

9 13 0.0003 0.017 15.3 0.2 2 21 539 558 538 559 0.93

10 13 0.009 0.52 10.6 0.4 3 23 569 589 567 589 0.97

11 13 9.1e-07 5.2e-05 23.2 2.8 1 23 595 618 595 618 0.98

12 13 3.6e-05 0.0021 18.2 1.4 1 23 624 646 624 646 0.98

13 13 0.00033 0.019 15.1 2.9 1 23 652 674 652 674 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	13	0.0073	0.42	10.9	0.3	2	23	32	53	31	53	0.96
2	13	0.0043	0.25	11.6	4.4	1	23	59	82	59	82	0.94
3	13	0.014	0.78	10.0	1.2	1	19	96	114	96	117	0.93
4	13	0.0095	0.55	10.5	4.1	2	22	133	153	132	153	0.91
5	13	0.33	19	5.7	2.0	2	23	398	420	397	420	0.94
6	13	0.013	0.76	10.1	0.3	1	23	445	467	445	467	0.97
7	13	0.0053	0.31	11.3	1.6	1	23	475	499	475	499	0.95
8	13	0.12	6.8	7.1	2.4	2	23	504	526	503	526	0.95
9	13	0.0003	0.017	15.3	0.2	2	21	539	558	538	559	0.93
10	13	0.009	0.52	10.6	0.4	3	23	569	589	567	589	0.97
11	13	9.1e-07	5.2e-05	23.2	2.8	1	23	595	618	595	618	0.98
12	13	3.6e-05	0.0021	18.2	1.4	1	23	624	646	624	646	0.98
13	13	0.00033	0.019	15.1	2.9	1	23	652	674	652	674	0.95

Sequence Information

Coding Sequence: ATGGAAACCGAGTCGATGGCCCCCAGCAGCAGTGCGGCGGCTGCGGCCACCAAACTCCTGGTGGAGATCACCACGGACGGGGTGCCCAAGCTACACTGCCCGGTGTGCAACAAGGCACTGGTCTCCTTAGCCGGATATGTGAAGCACGTGAAGAAGCACCAGCCGCCGGGCGGCTTCGAGTGCCGCCACTGCGATGCTCGGTTCTGCCACGAGGAGGAGCTGACCCAGCACGCCAAGGATGAGCACGGAGTCACCGGCGCGGCAGCTAGCCAGGAACGCAAGCCCTTCGTTTGCGAGAACTGCGGTGCGGAGTACAAGTATCAGGAGGCGTATCGCCGCCACTGCAGGACCAAGTGTGGCGAGGAGAAGCCATCGAAGGAGGAGTCGCGACCCATGGAGTGCAAGTGCTGCTTCACCCGCTtttccagcagctccaatctAACCAAGCACCGACGCAGTCGCCCCGACACCTGTGGCCAGCCGGAGTACGATTCGCCTGGCAAATCGATGAAACGAAAGTCCTTCCGCAAGGGCAGAAAGAGGGACTCCGATGATGACACCACCACCGAAGAATCGGACAGCGACGATGACATTCCTCTGGCCAGCCGGCTGAAGACGAAGCTGAAGCAGGAGAGCCAGAACTCGGACTCGGGCGACGAGTGTCCCGACTTTGAGCCAAACAACAGTGAGGACGATGCGGATGCATCCGGATTCCAGCTGCCTCCGCCGGCCATGGTCAAGGTTGAGGCCTTTGACGAAGAGGATTTCGAGTACCAGGACGCCAGCATGTATGTGAAGACCGAGAGTACCGATATATTCAGCAACGAAAAGGATAAGCTCCTGGATGTGCTCCTCAACGAGGGTGATGGTCTAAAGCCCTTCGAAAGCTTGAAAGTGGAGCAGGGCGCTGGTATACTGGACGAGATCGCGGCCGTGCCGCTGGTGGAGGTGGCCGAAGAAGACGTACTGGCCCTCAGGGGTCATAACAAGGAGCACACTGGGGAAAAACGGAAACGAGGCAGGCCGCCCAAGGAGAAGATACCTGTGGTCAAGAGAAAGTATCGCAAGCGAAACCAACCGAGATCGCCCTCGCCTGAAGATTCGTCAAGTACTCCAAAACGCGTAGCTAAGATCAGCAAAAAGGAGCTAAAGGAGCGCCTCAAGATGATCAACAAGATGGAGAAATCCTGGAAGTGTCCGCATTGCGTTAAAATATACCACATCCGCAAGCCGTATGAAAAGCATTTGCGCGACGACCACAAGTTAAATGAGGCGGAGATGAAGGAGATCTTCAAGGACGTGGACGTGCATGCCAAGCTGGATGAGGAGGTCTTCAAGTGCCCCATATGCAGCAAGATCTATTTGGTGGAGAAGCGCTTGGTCACCCACATGAAGGTGCACGGCGAAGATGGCAAGCTGACCTTTAAGTGTCCCTGCTATTGCAACCTGTTCTTCGCCACCAAGGAACAGGCCACGGAGCACGCTCGGGCCCAGCACAAGGAGCTGCTCTACTGCGAGAAGTGCGACAAGTACATGACCGGCCACGACAGCCTCAAGAACCACGAGCGCAACTTCCACTCGAAGAAGGAGCCGCGCAGCCAACAGCGCAACCTCATCTGCGACAAGTGCGGCAAGAAGTTCACCGGACGCACGTCGCTCTCAGACCACGTGCGATCCGACTGCGGCCGCCTTCCGCTTTACGGCTGCAGCGTATGCGGCAAGCATTTGTCCACAGCTGGTATTCTCAAGACGCACATGCTGCTCCACAAGGCAGACACACCGTACCAATGCGACAAGTGCGGCAAGACATTCAAGGTGAAGGCACAATACAAGTCTCACTTGAAGACGCGGCACACGGACTACAAGCCGTACAAGTGCCACCTGTGCCCCAAGGAGTATCCGTACAGGGAGAGCCTGCTCACCCACATGACCGTGCACACGGGCATCAAGCGATTCCTGTGCAATAACTGCGGCAAGCGCTTCACTTGCATCTCCAATTTGCAGGCCCATCGCAAGGTGCATGCCGACACCTGTGGCCAGTTGCCTTTGAATGCCAAGGCCACCCAGTACATGGGCGTGCAGCGTGGAAAACTCCTGATGGGCGCCAAGCCAGAGGCGGGCATGGAGTACGAGGAGACCAAGACTCTGATCGCCCAGGACGTCATCGACAGGGACATGCCCATGGCCCAGGAGCTGAACTTCCCATCCGACGGCTCTGCGCCACTGGCCACCGTGCCGCTGAACTACGCCTCCACGCACTTGGTGCCACACATCGTACTGCAGACCATGCAAGCCGAGGCCCGGCGATTGGAGTAA
Protein Sequence: METESMAPSSSAAAAATKLLVEITTDGVPKLHCPVCNKALVSLAGYVKHVKKHQPPGGFECRHCDARFCHEEELTQHAKDEHGVTGAAASQERKPFVCENCGAEYKYQEAYRRHCRTKCGEEKPSKEESRPMECKCCFTRFSSSSNLTKHRRSRPDTCGQPEYDSPGKSMKRKSFRKGRKRDSDDDTTTEESDSDDDIPLASRLKTKLKQESQNSDSGDECPDFEPNNSEDDADASGFQLPPPAMVKVEAFDEEDFEYQDASMYVKTESTDIFSNEKDKLLDVLLNEGDGLKPFESLKVEQGAGILDEIAAVPLVEVAEEDVLALRGHNKEHTGEKRKRGRPPKEKIPVVKRKYRKRNQPRSPSPEDSSSTPKRVAKISKKELKERLKMINKMEKSWKCPHCVKIYHIRKPYEKHLRDDHKLNEAEMKEIFKDVDVHAKLDEEVFKCPICSKIYLVEKRLVTHMKVHGEDGKLTFKCPCYCNLFFATKEQATEHARAQHKELLYCEKCDKYMTGHDSLKNHERNFHSKKEPRSQQRNLICDKCGKKFTGRTSLSDHVRSDCGRLPLYGCSVCGKHLSTAGILKTHMLLHKADTPYQCDKCGKTFKVKAQYKSHLKTRHTDYKPYKCHLCPKEYPYRESLLTHMTVHTGIKRFLCNNCGKRFTCISNLQAHRKVHADTCGQLPLNAKATQYMGVQRGKLLMGAKPEAGMEYEETKTLIAQDVIDRDMPMAQELNFPSDGSAPLATVPLNYASTHLVPHIVLQTMQAEARRLE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00615081;
90% Identity: iTF_00606536;
80% Identity: -