Basic Information

Insect: Drosophila subpulchrella
Gene Symbol: -
Assembly: GCA_014743375.2
Location: NC:12805446-12809165[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.0021 0.12 12.6 5.0 1 23 192 215 192 215 0.97

2 12 5.7e-06 0.00033 20.7 6.0 2 23 222 244 221 244 0.96

3 12 0.01 0.6 10.4 9.0 2 23 483 504 483 504 0.97

4 12 1.9e-06 0.00011 22.2 2.9 1 23 510 533 510 533 0.95

5 12 0.00064 0.037 14.2 0.8 1 23 538 561 538 561 0.93

6 12 6.2e-05 0.0035 17.4 5.5 1 23 579 601 579 601 0.96

7 12 2.3e-05 0.0013 18.8 0.7 1 23 606 628 606 628 0.98

8 12 3.2e-05 0.0019 18.3 1.7 1 23 634 656 634 656 0.95

9 12 2.3e-05 0.0013 18.8 0.7 1 23 662 684 662 684 0.98

10 12 3.4e-07 1.9e-05 24.5 2.7 3 23 692 712 691 712 0.99

11 12 2.5e-08 1.4e-06 28.1 1.1 1 23 718 740 718 740 0.99

12 12 0.37 21 5.5 3.4 1 19 745 763 745 768 0.89

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.0021	0.12	12.6	5.0	1	23	192	215	192	215	0.97
2	12	5.7e-06	0.00033	20.7	6.0	2	23	222	244	221	244	0.96
3	12	0.01	0.6	10.4	9.0	2	23	483	504	483	504	0.97
4	12	1.9e-06	0.00011	22.2	2.9	1	23	510	533	510	533	0.95
5	12	0.00064	0.037	14.2	0.8	1	23	538	561	538	561	0.93
6	12	6.2e-05	0.0035	17.4	5.5	1	23	579	601	579	601	0.96
7	12	2.3e-05	0.0013	18.8	0.7	1	23	606	628	606	628	0.98
8	12	3.2e-05	0.0019	18.3	1.7	1	23	634	656	634	656	0.95
9	12	2.3e-05	0.0013	18.8	0.7	1	23	662	684	662	684	0.98
10	12	3.4e-07	1.9e-05	24.5	2.7	3	23	692	712	691	712	0.99
11	12	2.5e-08	1.4e-06	28.1	1.1	1	23	718	740	718	740	0.99
12	12	0.37	21	5.5	3.4	1	19	745	763	745	768	0.89

Sequence Information

Coding Sequence: ATGGCAACGCACCAGCCGCACGCGCAGCTGGAGCCGGGTTCGGgtcaggagcaggagcagtcGGCTGGCCAGCCGGCGGGCAGCAAGATGATTCTCCTCAACGCAGTGGACACCACCATGGACACGGAGCGCGTCTGTCGCGTTTGCCTGAAGGACGCCTCGCTGGACGGGGAGTTGCACTTCATCTTCAACGATACGCCCGTCGAGGAGGATGCCAATCTGGCCCGCATCCTTGACGAGTGCACCCTGCACCAGTGTCATCGGCACGACGGGATGCCCCCGCATATGTGCGGCCCTTGCGTGGACGCGGCCCGCCATGCCTATCGCTTCAAGCGGCACGCGGAGCGCTCCTACTGCTCGCTAGTGGCACTGCTGGGCCGCTCGCCCCAGCTGAAGGCTCGCGGCGCCGAGGCGTCCAGCCAGACGGACCAGGTGGCCCTGCTGCCCTGCGAGATGTGCCACGACCAGTTCCTTAACAGCCTGGAGCTCCGCCTGCATCGCAATCAGGTGCACAGGACGAACAAGGATGGCAGCGTCGCTACGGGGACGGATGGCCAGCAGCAGGCAGAGGAATTCAAGTGCAAATTTTGCCCGCAGCATTTCCCGCATCTCCGACAGCTACGCAGCCATTTGGCGCGCAGCCACGAGCAGGTAACGCGACTCCAGTGCGGCCAATGCCATCGCACCTTTAGCCGTCGTGATCATTTGCTGCGCCACATGCGCAACAAGCATCGCGACCTGGACGACGACCTTCTGCGCACCTGGCCGCCGGCGGATGAAAATACCATGAACAGCGACGGCGGGGACGAGCTGGTCTCCGCTGAGGTGCTGCTGAACGAGGAGGACGACGACCATGATGGGGTCGGTGAAGCTTTCCAGTGCAATACGAATCCCATTTCCAGCAACGAGGAGGACGATGAGGATGACGAAGAGCCCAATGTGACCAATCAAACTCTGTGGCTGCACATTAAGCCGGAGCCCTGCCTGGAGGCGGAGGAAGTCGACCTGGCCATGCAGCTGAAGCTCGAGAAGAAGCGTCGACGACGGGAGAAGGCGGAGGCCCAAGCCGAGGGCTCCATGAATCGGCCTGTAAAGGATGAGCCCATTGCCATCGGCGACTCGCCGTTTAGCATTAAGGAGGAGAGCCACCCTGTGGGCAGCGAGGACGAGGCACCAATGGGAGTGGAAGATTTCATGAAGCTGCATGTCAGTGGCGAACTGACGCTTAGTGACGAGGACCGGTTCGGCGAGTTCGTGGACGATGATAGCGACctggatgaggatgaggacgacgacgacgacgacgacggtGGTGAAGATGGTGGTGAAGACGAGGATGGGGAATACCGGCTCAAGCAGGAGCCGCTAGACGGCGAGAAGCCGCCGAAGAAGTCCAAGTCCGGAAGGCGACGGCGCCGCAATAAGGGCGAACCCAATCCCGAGAACCGCTGCGAAGTGTGCCAGCGCACCTTCTCACGCCACTGCCACCTGCTGCGTCACAAGCTGTCGCATTTGGAGAAGAAGCCGCACAACTGCCCACACTGCCCCAAGGCGTTCGCGCGCAGTGACCACCTCAAGGCGCATGTGCAGAGCCTGCACAGCAACAAGGAGCACAAGTGTTCGCTCTGCGAGGCTGCCTTTTCGCGACTGGACGCCCTGGAGCGTCACAAGGTCAGCAAGCACAATGGCGAGGGTCTTGAGCCGGGCAGCGAACTGAAGCTCCAGCTGGCGGAGCACACATGCGAATACTGCTCCAAGCGTTTCTCCAGCAAGACCTACCTGCGCAAGCACACGCTGCTGCACACCGACTTCCTCTACGCCTGCAAGACCTGCGACGAGACATTCCGCGAGCGAGCGCAGCTCAGGGAGCACGAAAAGACCCACACCGGGCAGCGCAACTTCCTGTGCTGCATCTGCGGCGACAGTTTCGCTCGCAACGACTACCTCCGAGTGCACATGCGTCGCCACAACGGCGAGAAGCCCTACAAGTGCCGCTACTGTGTCAAGGCCTTTCCCCGCGCCACCGATCTCAAGGTCCATGAACGTTACCATACGGGCACCAAGCCGAATCTGTGCAATACATGCGGCAAAAGCTTCCACCGTGCCTACAACCTGACCATCCACATGCGCACGCACACCGGTGAGCGGCCCTATAAATGCGACCAGTGTCCCAAGAGCTTCACGCAGAGCAACGACCTCAAGGCGCACATCCGGAGGCATACGGGCGAGCGGTACAAGTGTCCGCACTGCGACGCCTACTTCCTGCAGCTGTACAATATGCGCAATCACTGTTTGAGCGCCCACAACAAGCACATCGAGACGAAGACTGGCCGTCTGCAGCGGACGGGCCTGCTGGACGATGGCGGGCAGTCGCATTTGACCACCGTGGTCATGCCGCCGGCACGGTATCCACATGATTTGGATCCCCAGCTGGCCGTGGTGGCCGCAGCTGCTGGCACTGAGAGCTCATCCGCGACTACCGTCATCCACTCACCGGGAACGTACAATGCCACGCAATCCTCTGGACTGGCGCCGGGATCAGCGGCCGCTGCTCCAACCAGCACCCTCGATGGAGCCAGCTTTGTGCCCACGACGGTGAATGCGACGGCTGCTCCGTTTGGCGCCTTCAACTTTCCGCCTGTCGTTATGGCGCATCTCATGTACAACCACGGAGGAAGCAGCCAGCACAGCCAGAGTGGAAGTGACACGGGCAAATAG
Protein Sequence: MATHQPHAQLEPGSGQEQEQSAGQPAGSKMILLNAVDTTMDTERVCRVCLKDASLDGELHFIFNDTPVEEDANLARILDECTLHQCHRHDGMPPHMCGPCVDAARHAYRFKRHAERSYCSLVALLGRSPQLKARGAEASSQTDQVALLPCEMCHDQFLNSLELRLHRNQVHRTNKDGSVATGTDGQQQAEEFKCKFCPQHFPHLRQLRSHLARSHEQVTRLQCGQCHRTFSRRDHLLRHMRNKHRDLDDDLLRTWPPADENTMNSDGGDELVSAEVLLNEEDDDHDGVGEAFQCNTNPISSNEEDDEDDEEPNVTNQTLWLHIKPEPCLEAEEVDLAMQLKLEKKRRRREKAEAQAEGSMNRPVKDEPIAIGDSPFSIKEESHPVGSEDEAPMGVEDFMKLHVSGELTLSDEDRFGEFVDDDSDLDEDEDDDDDDDGGEDGGEDEDGEYRLKQEPLDGEKPPKKSKSGRRRRRNKGEPNPENRCEVCQRTFSRHCHLLRHKLSHLEKKPHNCPHCPKAFARSDHLKAHVQSLHSNKEHKCSLCEAAFSRLDALERHKVSKHNGEGLEPGSELKLQLAEHTCEYCSKRFSSKTYLRKHTLLHTDFLYACKTCDETFRERAQLREHEKTHTGQRNFLCCICGDSFARNDYLRVHMRRHNGEKPYKCRYCVKAFPRATDLKVHERYHTGTKPNLCNTCGKSFHRAYNLTIHMRTHTGERPYKCDQCPKSFTQSNDLKAHIRRHTGERYKCPHCDAYFLQLYNMRNHCLSAHNKHIETKTGRLQRTGLLDDGGQSHLTTVVMPPARYPHDLDPQLAVVAAAAGTESSSATTVIHSPGTYNATQSSGLAPGSAAAAPTSTLDGASFVPTTVNATAAPFGAFNFPPVVMAHLMYNHGGSSQHSQSGSDTGK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00504826;
90% Identity: iTF_00486710;
80% Identity: -