Dsup013876.1


Basic Information
Transcription Factor Domain
Sequence Information
Similar Transcription Factors

Basic Information

Insect
Drosophila subpulchrella
Gene Symbol
-
Assembly
GCA_014743375.2
Location
NC:13302816-13305604[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 17 1.3e-06 7.5e-05 22.7 3.2 2 23 181 202 180 202 0.98
2 17 2.7e-05 0.0015 18.6 0.4 1 23 207 229 207 229 0.95
3 17 6.7e-08 3.9e-06 26.7 0.4 1 23 235 257 235 257 0.98
4 17 1.4e-05 0.0008 19.5 6.4 1 23 263 285 263 285 0.99
5 17 0.0053 0.3 11.3 0.5 1 23 290 312 290 312 0.98
6 17 8.8e-05 0.005 16.9 4.4 2 23 319 340 318 340 0.97
7 17 1e-05 0.00059 19.9 5.2 1 23 346 368 346 368 0.99
8 17 1.9e-05 0.0011 19.0 7.5 1 23 410 432 410 432 0.98
9 17 0.00027 0.015 15.4 0.2 1 23 437 459 437 459 0.95
10 17 7.5e-08 4.3e-06 26.6 0.4 1 23 465 487 465 487 0.98
11 17 9.1e-06 0.00052 20.0 3.7 1 23 493 515 493 515 0.99
12 17 0.0051 0.29 11.4 0.1 2 23 521 542 520 542 0.96
13 17 8.8e-05 0.005 16.9 4.4 2 23 549 570 548 570 0.97
14 17 0.0003 0.017 15.3 3.1 1 23 576 598 576 598 0.99
15 17 1.8e-05 0.001 19.1 0.4 1 23 604 626 604 626 0.95
16 17 4.3e-06 0.00025 21.1 0.7 1 23 632 654 632 654 0.98
17 17 6.5e-05 0.0038 17.3 9.1 1 23 660 682 660 682 0.98

Sequence Information

Coding Sequence
ATGGGGTCTTCAGTGTGCCGCGTTTGCCTGGCAAATTGTGAGAATATGATCAATATTTTCGATGTGATTGAGGGAAATCCAATTTCGACTATGCTTTCTGAGTGTACCGGATTTAAAGTTGAGAAAGGTGACCGGTGTCCAGAAAACATTTGCACATCCTGCCTGCAGGATGTAAAAGTTGCGTTTAAGATGAAGAAAACATACGAAAGGAGTCGCCAGATCTACGGCCAGTTAAATAGGGATTCATTGGAGGGCGACATACTCGAGGAATCAAACACTAAAGAAGGAGGTCTTGAGTATGCTAGCCAAGTTAAAGAAGAAAGCGATGATCTGCTATGGAAGGAGGAATCACATAGCTACCTTTGCCAAGTGAAGAACGAACCAGTTGATGAAGACATGCTTGAGGAGGAGCACAGTCCTTTATCAGAGGGCAATATCAATCAGTCCGATAGCCAAGTGAAGGTCGAGGAATCAATATATGACGGATCCGATGAGGACCATGATTCTGTTGATCATGAAAGTAAGATATACAGTCCGAATAAATGCCCGCAGTGTCCAAAGACTTGTATATCAAAATCAGATCTTAAGCGACACTTGCGCAGCCACATAAGAGAACCATTTCGGTGCTCCGTTTGCTCAAAGATTTTTGCAAATAGAGCGAATCTTTTAAGGCATTTCGTTATCCACGCGGGAGAACGTCCTTTCGAGTGCTCCCGATGTCCAAAGACGTTCACCCAGGCCGCAAATCTTCAGATACACATGCGACTCCACACAGGAGAACGTCCTTTCCAGTGCTCCCATTGCTCTAAAACCTATACTTTAAATTCACATCTTCAGGTACACCTTAAAACCCACACGGACGGGCAGTTCCAGTGCTCTCAGTGCTCAGACACGTTTAATAATGGATCAGATCTTATGTTACACGAGCGACTGCACGCTAGAGACCAACCACTAAGTTGTACCCACTGCTCAAAGGCTTATATAAAGGAGTCGCATCTTCGGAAACACTTGCTAACCCACCCAGAAGAACAACATTATAAGTGTACCCACTGCTCAAAAACTTTCTCAGACGATTCCGTTTTTCAAAAACACTTACGAACCCACGAAGAGGGCAACATTGATCAGTGCGATAGCCAAATAAAGATGCAGACAACAAAAGATGATGGAACTGATGCCATTAATAAGGACCACGGTTCTCTTAATAATGAAATGAATCCTTACAGTCCGCATAAATGCACGCATTGTCCGAAGATTTGTATATCAAAATCAGATCTTAAGCGACACTTGCGAAGCCACAAAAGAGAACCGTTCCAGTGCTCCGTTTGCTCTAAGATTTTTGCGAATGGTGCTAATCTTTCAAGGCATTTCGTTATCCACACAGGAGAACGGCCTTTCAAGTGCTCCCGATGTCCAAAGGCGTTCACCCAGGCCGCAAATCTTCAGATACACATGCGACTACACACAGGAGAACGTCCTTTCCAGTGCTCCCTCTGCTCTAAGACCTATACTTTAAATTCCCATCTTCAGGTACACCTTAAAACCCACACGGAAGGGCAGCTCCAGTGTTCTCAGTGCTCAGAAGTGTTTGAAAATGGAACCGATCTTATGTTACACGAGCGACTGCACGCAAAAGACCAACCACTAAGTTGTACCCACTGCTCAAAGGCTTATATAAAGGAGTCACATCTTCGGAAACACCTGCTAACCCACTCAGAAGAACAAAATTATAAGTGCGCCCACTGCTCAAAAACTTTCTCAGACGACGccatttttcaaaaacatttACGAACCCACAAAGAAACTCGACCTTTCCAATGCTCCCTTTGCCCAAAGGCTTTTACAAGTGGTTCCAATCTTTCAAGGCATTTCGTTATCCACACAGGAGAACGGCCTTTCAAGTGCTCCCGATGTCCAAAGGCGTTTAGGCAAGGCGCATATCTTAGGATACACATGCGACTCCACACAGGAGAACGCCCATTCCAGTGCTCCCATTGCTCTAGGTGTTACACCACGAATTCGCATCTTCAAATACACCTGAAAAATCACAAAGAATAA
Protein Sequence
MGSSVCRVCLANCENMINIFDVIEGNPISTMLSECTGFKVEKGDRCPENICTSCLQDVKVAFKMKKTYERSRQIYGQLNRDSLEGDILEESNTKEGGLEYASQVKEESDDLLWKEESHSYLCQVKNEPVDEDMLEEEHSPLSEGNINQSDSQVKVEESIYDGSDEDHDSVDHESKIYSPNKCPQCPKTCISKSDLKRHLRSHIREPFRCSVCSKIFANRANLLRHFVIHAGERPFECSRCPKTFTQAANLQIHMRLHTGERPFQCSHCSKTYTLNSHLQVHLKTHTDGQFQCSQCSDTFNNGSDLMLHERLHARDQPLSCTHCSKAYIKESHLRKHLLTHPEEQHYKCTHCSKTFSDDSVFQKHLRTHEEGNIDQCDSQIKMQTTKDDGTDAINKDHGSLNNEMNPYSPHKCTHCPKICISKSDLKRHLRSHKREPFQCSVCSKIFANGANLSRHFVIHTGERPFKCSRCPKAFTQAANLQIHMRLHTGERPFQCSLCSKTYTLNSHLQVHLKTHTEGQLQCSQCSEVFENGTDLMLHERLHAKDQPLSCTHCSKAYIKESHLRKHLLTHSEEQNYKCAHCSKTFSDDAIFQKHLRTHKETRPFQCSLCPKAFTSGSNLSRHFVIHTGERPFKCSRCPKAFRQGAYLRIHMRLHTGERPFQCSHCSRCYTTNSHLQIHLKNHKE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-