Basic Information

Insect: Drosophila suboccidentalis
Gene Symbol: Mtf1
Assembly: GCA_037043435.1
Location: JBAMBK010001507.1:93778-98737[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 0.00011 0.0079 16.8 1.9 1 23 94 118 94 118 0.99

2 6 0.00022 0.016 15.9 0.4 1 23 124 148 124 148 0.98

3 6 0.00032 0.023 15.4 2.6 1 23 154 178 154 178 0.97

4 6 1.3e-07 9.6e-06 26.0 5.1 1 23 183 205 183 205 0.98

5 6 9.8e-07 7.2e-05 23.3 3.2 1 23 211 235 211 235 0.99

6 6 0.00012 0.0087 16.7 3.7 1 23 241 265 241 265 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	0.00011	0.0079	16.8	1.9	1	23	94	118	94	118	0.99
2	6	0.00022	0.016	15.9	0.4	1	23	124	148	124	148	0.98
3	6	0.00032	0.023	15.4	2.6	1	23	154	178	154	178	0.97
4	6	1.3e-07	9.6e-06	26.0	5.1	1	23	183	205	183	205	0.98
5	6	9.8e-07	7.2e-05	23.3	3.2	1	23	211	235	211	235	0.99
6	6	0.00012	0.0087	16.7	3.7	1	23	241	265	241	265	0.95

Sequence Information

Coding Sequence: ATGGTGGAGGGGGGATTCTCAGCTGTCAGCTGTGTCCGTGACAGGGACAGCGACTGCAAATGGTGGGTGACGGGGGTGGGGAGTATAGTGATGACGCAGGGCGGAGGGTATGTCTGGTACCCCCAGGCCCATCCCAGTCCCTATATCGAAGAGCAGAATGAGCcagacgatgacgatgagcTGGCTCACTGCATACACCCGGGCGCCTTGCATAAGGACACCGATGAGGATCAACTGATGGCGATGGCGTACGAGAGCTCCGACGAAGCTCTTAGCCGTTATAAATGCAACTATGAGAACTGTTATCGCAGCTACAGCACGATTGGAAATCTGCGAACGCATTTAAAAACCCACACAGGTGACTACAGCTTCAAGTGCACGGAGGAGGGCTGCAACAAGGCGTTCCTCACATCCTACAGCCTGAAGATTCATGTCCGCGTCCACACCAAGGTGAAGCCCTACGAGTGTGAGGTGAGTGGCTGTGATAAGGCGTTCAACACACGCTACAGATTGCACGCCCATCATCGCCTGCACAATGGCGAGACATTCAATTGTGAAATGTGCCAGAAATGCTTCACCACGCTGAGTGACCTGAAGAAGCATATGCGCACCCATACCCAGGAGCGTCCCTACAAGTGTCCCGAGGACGATTGCGGCAAAGCGTTTACCGCCTCGCATCATTTGAAGACGCACCGACGCACGCACACCGGGGAGAAGCCGTATCCTTGCCAGGAGGACAGTTGCCAGAAATCGTTTAGTACCTCGCACAGTCTCAAGTCGCACAAGAAGACGCATCAGCGTCAGATGCTCAACAAGggaggacGAAGAGGAGCAGCGGAGCAGCAAccggagcaacaacaatttaaagtcAAACAGGAAATCGAAGTTACCGACATGGTGCTACTTAATCCAGGCAGTCACAGCTCGGAGACAACGAGCAATGACAGCGGCGTTGTGCTGCAGCAAGTGTCCAATGTTTTCATGCTGCCAGAGACATCGCAGGCGTATCCATTGTCCTATGCCGCCGAGGAGGAGATACCCAGTCCCTGGATCGATGCTGGCGTGCTCGTCTCCAAGCCCATTATGGCCATGGCGCCGTTAACCGACGCTTGCGTTGCCTTGCCCACTGAAATGCCCAGTTTTGTGGATCTGAAGCAGAGCTTTGGTAATGCCATCAGCGGCAACATGGATGACTTGACAATGACACCATCACTGGATGTGGAAATGTTGAACAGCACCAATAATAATACTAATCAAACTGTAACTGATCCTGCCACTTTGCCCACGCTGGAGTTGAATCCGCAGAACATTGAGGAACTGCTCAAGGATGATAGCTTCGACAATGACGAGGACATGGAGACAGAGTCTCTGCTTAACGATATACTTATGACCattgacaacaacagcgcCTTGTTGCAGGCGACGCTGCATCAGGCGGCCCAGGTGCCCAGCGATGCCTCCGGTTTGGTGGAACTGGACATCAGGGACAACAAGCCGACCCTGAAACAGATCACAGCAGATGCGGGCATCTGTAATTGCACCAATTGCAAGTGTGATCAGACCAAGAGCTGTCACAGCGGTGACTGTGGTGGTGGCGCCTCCACATTGAAATCTGTGAAACCcaccacgacaacaacaattgccagCAGCTCCAATGGCGTGGCCGGGGGCAAACGCATCTGTGGCAGCACTGTCACCAAAAAAGTGAGTAAACGCGATGCGGAAATGAACCAAAACATCGAGGATGTTGCTCTGCTCTTGCAAAATCTGGCTTCTATGAGTGGCGGCAGCAGCTCGgctggcggcggcggtggaTGCTGTGGCggtggtgttgctgctgccaagcCTGCGCCTCCTGCAGCTACCAATGGTTGTGGTTGCTCCTCAAGTGCACCGAAGCCAGCGGCAACTGGTGGTTGCTGTGGTTCCGCTCCAGCGCCAGCTGTCAGCTCCGGCTGCTGTTCGGGCAATAACCCCGCTGCTCCAGTCGCCGCCAGTGGTGGTTGCTGTGCACCACCGGCACCAGCACCCGTTGTGGTGGCTTCCTCTGGCTGTTGCTCCAACAAATCGCCGCAGCCGCCGCCTGCcgtcatcagcaacagcagcagcaatgcaGTCAAGGGCAACTCCTGCACCTGCAAGAGTCCGGCGGAGGGCGTGGCCAACGGTTGCTGCGTCGTCATCTGCATGAAAACATTGCAAGCCTTGCGCAAAGTTCTGACACGCCGGAACCTCAATTTAATGCTTTGTCCGCAGCAGAGTTAA
Protein Sequence: MVEGGFSAVSCVRDRDSDCKWWVTGVGSIVMTQGGGYVWYPQAHPSPYIEEQNEPDDDDELAHCIHPGALHKDTDEDQLMAMAYESSDEALSRYKCNYENCYRSYSTIGNLRTHLKTHTGDYSFKCTEEGCNKAFLTSYSLKIHVRVHTKVKPYECEVSGCDKAFNTRYRLHAHHRLHNGETFNCEMCQKCFTTLSDLKKHMRTHTQERPYKCPEDDCGKAFTASHHLKTHRRTHTGEKPYPCQEDSCQKSFSTSHSLKSHKKTHQRQMLNKGGRRGAAEQQPEQQQFKVKQEIEVTDMVLLNPGSHSSETTSNDSGVVLQQVSNVFMLPETSQAYPLSYAAEEEIPSPWIDAGVLVSKPIMAMAPLTDACVALPTEMPSFVDLKQSFGNAISGNMDDLTMTPSLDVEMLNSTNNNTNQTVTDPATLPTLELNPQNIEELLKDDSFDNDEDMETESLLNDILMTIDNNSALLQATLHQAAQVPSDASGLVELDIRDNKPTLKQITADAGICNCTNCKCDQTKSCHSGDCGGGASTLKSVKPTTTTTIASSSNGVAGGKRICGSTVTKKVSKRDAEMNQNIEDVALLLQNLASMSGGSSSAGGGGGCCGGGVAAAKPAPPAATNGCGCSSSAPKPAATGGCCGSAPAPAVSSGCCSGNNPAAPVAASGGCCAPPAPAPVVVASSGCCSNKSPQPPPAVISNSSSNAVKGNSCTCKSPAEGVANGCCVVICMKTLQALRKVLTRRNLNLMLCPQQS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00519463; iTF_00901747; iTF_00806231; iTF_00523226;
90% Identity: -
80% Identity: -