Basic Information

Insect: Drosophila suboccidentalis
Gene Symbol: wek
Assembly: GCA_037043435.1
Location: JBAMBK010002337.1:158906-160714[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.00065 0.047 14.4 1.2 3 22 287 306 285 306 0.94

2 8 0.0005 0.036 14.8 1.8 2 22 334 354 333 354 0.94

3 8 0.00017 0.013 16.2 0.1 2 23 368 390 368 390 0.94

4 8 4.4e-05 0.0032 18.1 0.6 1 23 396 418 396 418 0.97

5 8 0.0029 0.21 12.4 0.3 1 23 424 446 424 446 0.97

6 8 0.0013 0.096 13.4 0.2 1 23 451 473 451 473 0.96

7 8 1.3e-06 9.5e-05 22.9 2.1 1 23 479 501 479 501 0.99

8 8 0.016 1.2 10.0 5.3 1 23 507 530 507 530 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.00065	0.047	14.4	1.2	3	22	287	306	285	306	0.94
2	8	0.0005	0.036	14.8	1.8	2	22	334	354	333	354	0.94
3	8	0.00017	0.013	16.2	0.1	2	23	368	390	368	390	0.94
4	8	4.4e-05	0.0032	18.1	0.6	1	23	396	418	396	418	0.97
5	8	0.0029	0.21	12.4	0.3	1	23	424	446	424	446	0.97
6	8	0.0013	0.096	13.4	0.2	1	23	451	473	451	473	0.96
7	8	1.3e-06	9.5e-05	22.9	2.1	1	23	479	501	479	501	0.99
8	8	0.016	1.2	10.0	5.3	1	23	507	530	507	530	0.94

Sequence Information

Coding Sequence: ATGACTGAACACAATGTGAATCCAATTACCAAGAGCCATTGGCTAAATTGGTGTCGGCTATGCGCCAAGGATGACGTCCGCTTCAACGTAAAGGTCTGCACAAGCGAGAGTGCAAACAATACCTGGAACAGTGTTCTGGTGATGGCCATCAGAAAGCATTTTGCTGTACATATGCGATTGGAGGATGAGCTGAGCGGTGTTCTTTGCAAGGAATGCTATACGCTAATAAGCGAGCTAATTGATTTCGAGGCACACGTCAACAAAGTTCAGGCAATCTTTGAAATATTGCGACGCTCTGAGCCAAGTGAACACTTGAATGTGGAAGCTCTACGGCTGCAGAATGGTCTGCGTGAGGAAGATTGGACGCACATAATCAAGCCAGTCTTGGACATTGAGCACAATGTCACGAAAACAGACCTAATTGTTGTGCCAAAACAGGAGTTTATTGATTGGGGCGAGGGCGAGACACTCGAAAATCTAGATGAAAGTAATGTTAACAGCCTACAAATCGAGGAAATAATAATTCCTGGCTGGGATGCAGCAAATGATACTCAAAATAATACCAACAAAAGACTGCGCGGCCGGCGAAGAACTTGTCAATTGTCAAATGCAGATTCCACAGAGAAAAGCGAAGAAGATCTCGATGTAGTGCTGAAAGTCGAGTTAATTGATGAGACACCAATTGTAGCGGAAAATGAATCTTCAAGCGTCGTCGCTGAATTGGAATTTCCGCCGGAAAGTCCAACAACTTCCTTCGTAGAACCAGAATTTCTTGGTTTTTCATCtgacagtgagagagaggacATTAGAACTGAGCCCGATGATTTGGATAGCTCGTCGagacgaaaaaaaataaattgcaaatggtGCAATAAAGTGTACCACAATCCTACATCATATCAAAAGCATCTACGAAAAGTCTGTCGGAAATTCGAGGGTATTAGAACTGAAACCGATGATTTGGATAGTTCATCGAAGCGCAGGAAACGAACAAAATTAGAGTGCAAACGGTGCGATAAAGTATACCACAATCCTAAATCATATCAAAAGCATCTACGAAAACGCTGTCGGAATGTAAAGAGAAAGGTAGATCAGAACGCGTACTGCGACCTGTGCAACAAAACCTTGTCGTCTGCCTCGGCGCTGAAAGTGCACATCGATGTAATGCACAAAGACTACAAGCGCTATATATGCGACCATTGTGGCAAGCAGTTTAAGACAATTGCGAATCTCGGCGAGCACAAGCTGGTGCATACGGACGATCGTCCATTCGTCTGTGCGGTATGCAGTATGGGATTCAAAAGCAAAGTTCGACTAAGAGTCCATTCTAAAATCCATGAGAATCTGAACTATGAATGCAACATTTGTGGCAAGAATATGCCGACACGCCGCTCATTGACATTGCACAAAGTGGTGCACAGCGAAGATCGCAAATTCAAATGTGATGTCTGTGATATGCTTTTCAAGCGCTCAAAAACCCTCAGGAGGCACATGCTCACTCATACGGGGCTGCGACCCTATGTCTGCAATTACTGTGAGCAAGCTTTCAGATGTAGTTCAAATTTACGTATGCACAAGCTCCACAGGCATCCACAAGAGTTCAAGAAGGAAGAGGACGGCGTCGTACCGTTGAGATTAAAAATACCCAAGCTAGAGGAACTGCCGGTCATGTCCAACCTGAAAACTGACCCCTAG
Protein Sequence: MTEHNVNPITKSHWLNWCRLCAKDDVRFNVKVCTSESANNTWNSVLVMAIRKHFAVHMRLEDELSGVLCKECYTLISELIDFEAHVNKVQAIFEILRRSEPSEHLNVEALRLQNGLREEDWTHIIKPVLDIEHNVTKTDLIVVPKQEFIDWGEGETLENLDESNVNSLQIEEIIIPGWDAANDTQNNTNKRLRGRRRTCQLSNADSTEKSEEDLDVVLKVELIDETPIVAENESSSVVAELEFPPESPTTSFVEPEFLGFSSDSEREDIRTEPDDLDSSSRRKKINCKWCNKVYHNPTSYQKHLRKVCRKFEGIRTETDDLDSSSKRRKRTKLECKRCDKVYHNPKSYQKHLRKRCRNVKRKVDQNAYCDLCNKTLSSASALKVHIDVMHKDYKRYICDHCGKQFKTIANLGEHKLVHTDDRPFVCAVCSMGFKSKVRLRVHSKIHENLNYECNICGKNMPTRRSLTLHKVVHSEDRKFKCDVCDMLFKRSKTLRRHMLTHTGLRPYVCNYCEQAFRCSSNLRMHKLHRHPQEFKKEEDGVVPLRLKIPKLEELPVMSNLKTDP

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00602086;
90% Identity: -
80% Identity: -