Basic Information

Insect: Drosophila suboccidentalis
Gene Symbol: -
Assembly: GCA_037043435.1
Location: JBAMBK010001359.1:120020-127191[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.00045 0.033 14.9 4.6 1 23 293 315 293 315 0.97

2 14 0.00013 0.0092 16.6 0.1 1 23 321 344 321 344 0.97

3 14 0.0079 0.57 11.0 0.7 1 23 350 373 350 373 0.86

4 14 0.003 0.22 12.3 5.9 1 23 400 422 400 422 0.96

5 14 0.044 3.2 8.6 2.6 1 23 428 450 428 450 0.98

6 14 0.00048 0.035 14.8 0.5 1 23 456 478 456 478 0.98

7 14 0.0096 0.7 10.7 4.8 1 22 484 505 484 508 0.91

8 14 0.00051 0.037 14.7 5.4 1 23 813 835 813 835 0.97

9 14 0.00013 0.0092 16.6 0.1 1 23 841 864 841 864 0.97

10 14 0.0079 0.57 11.0 0.7 1 23 870 893 870 893 0.86

11 14 0.18 13 6.7 8.1 1 23 929 951 929 951 0.95

12 14 0.0022 0.16 12.7 0.7 1 23 957 979 957 979 0.98

13 14 4.3e-05 0.0031 18.1 0.5 1 23 985 1007 985 1007 0.98

14 14 0.0096 0.7 10.7 4.8 1 22 1013 1034 1013 1037 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.00045	0.033	14.9	4.6	1	23	293	315	293	315	0.97
2	14	0.00013	0.0092	16.6	0.1	1	23	321	344	321	344	0.97
3	14	0.0079	0.57	11.0	0.7	1	23	350	373	350	373	0.86
4	14	0.003	0.22	12.3	5.9	1	23	400	422	400	422	0.96
5	14	0.044	3.2	8.6	2.6	1	23	428	450	428	450	0.98
6	14	0.00048	0.035	14.8	0.5	1	23	456	478	456	478	0.98
7	14	0.0096	0.7	10.7	4.8	1	22	484	505	484	508	0.91
8	14	0.00051	0.037	14.7	5.4	1	23	813	835	813	835	0.97
9	14	0.00013	0.0092	16.6	0.1	1	23	841	864	841	864	0.97
10	14	0.0079	0.57	11.0	0.7	1	23	870	893	870	893	0.86
11	14	0.18	13	6.7	8.1	1	23	929	951	929	951	0.95
12	14	0.0022	0.16	12.7	0.7	1	23	957	979	957	979	0.98
13	14	4.3e-05	0.0031	18.1	0.5	1	23	985	1007	985	1007	0.98
14	14	0.0096	0.7	10.7	4.8	1	22	1013	1034	1013	1037	0.91

Sequence Information

Coding Sequence: atggGATTTCCACGCAGTATTAAAAACGAACGGGAGAAATTGAAGAAGCACAAGAACAAAAAGTTGGTCGCTGAGCTGCTCGAGGAAGCAGAAGTACGGGAGGCAGCTGTTCCAAATTTTGTCAGCTCCACGGAAAATGCTTTCGTTCCGTTCACCTCCGCGTCATCAGAGAATGATCCCTTGGCTGAGGAACAGGTGAAGGCAGATAATGCCCCAACGAGCTATGAAAACGATGTTACTTTGGCCAATAAGATGAAATGTCGCACCTGCTTCCGcccttttgttgttgatgacaACGCAAAAGATCTGAGCAACGTGGAAAACGCTGTGATGCTATATCATATTGAATTTATCACCGGAATTTGGATCCAATGCAACGATGAAATTTCTCAATTCATGTGCTCCCATTGTGTTGACAACTTAAGCACAGCCATTGAGTTCCGAGAAACATGCATACGGACAGAACTTCTGCTCACAGGTGGCGACGATGTCGATCTTCCAGAGAACGGCATTGAATTGTGCGATAATGATGAGGTCGAACCGCAGACGGCTGACGATATAAAAGAGGAGGAATTCACCGAGGAAGCAACTGTAATTGAGCCGTCAACACGAGTAGTATCTAAAAAAACATCTGTAGCGGATTCAAGTAGCATTGCTTTGGGTGCCCAGATCTATGAGGAGCTTTTGAGTGAATATCAGGCAAAGGAGAAGActtcacaaacaaaacaaaagatggcaacaacaacaatcccaAACACCCAGTCGACAAAGAAAAGGAAACAAACACCACGGGAGCCAGCTCTCAAACGTACCAAACAAACGAGAGAGGAGAAAAATCGGATACGCCGTGAACAGAATAAAGCCTTGCCCCGCAATCATGTGTGCGATCAGTGCGGTTCATCCTTTCGATTTAGATGCAATCTCACAATACATATGCTGCGGCACACGCGCTCCAAGAACTATCCATGTCCGGAATGCCCCAAGCAGTTTTATGATGCCTATATGAGAAACATGCATATCCGTGTGAGTCACCGAGGCGAACTTCCCTTTGTCTGCAATTATTGTCCGAAAGCATTTAAAGCTTCTAGCTTACGTTATCTGCACGAGaaAAACGATCATGGAGCATCTCCGCGCATTCACAAgaatgtaaataaatcaaaccAAAGGATAGGACTCAAGAAAAGTCAGACGCAGCGTCACTGTTGTAGTTATTGCGATCAAAGCTATGTCACAAAATGCGCGCTGAACTGGCATATAAATCAACATTTAGGCCTAACTCCTTACAAGTGCAAGTGCTGCGATATGAGTTTTCCGAATCCTCAAGCGAAACAACGTCACGAGATGAGGCACGATAGTAAGCGTCCCTTCGAATGTGACATTTGTCTCAAAGGATTCTACACACGGATTAAGCTTAAAGAACATGAACGGATTCATACTGGCGAACGTCCTTACAGGTGTGACATTTGCGATTCCTTTTTCCGATACAAGTTCAACTTGCATTCGCATCAGTTTAGCAAAATGCATAAGGATAATTTGCTAAAGGCGCAAAAGGAGAAGATTGTCGAAGACTCAAgATTTCCAcgcaataataaaaacgaaCGGGAGAAATTGAAGAAGCACAAGAACAAAAAGTTGGTCGCTGAGCTGCTCGAGGAAGCAGAAGTACGGGAGGCAGCTGTTCCGAATTTTGTCAGCTCCACGGAAAATGCCTTCGTTCCGTTCACCTCCGCGTCATCAGAGAATGATCCCTTGGCTGAGGAACAGGTGAAGGCCACAACGAGCTATGAAAACGATGTTACTTTGGCCAATAAGATGAAATGTCGCACCTGCTTCCGcccttttgttgttgatgacaACGCAAAAGATCTGAGCGACGTGGAAAACGCTGTGATGCTATATCATATTGAATTTATCACCGGAATTTGGATCCAATGCAACGATGAAATTTCTCAATTCATGTGCTCCCATTGTGTTGACAACTTAAGCACAGCCATTGAGTTCCGAGAAACATGCATACGGACAGAACTTCTGCTCACAGGTGGCGACGATGTCGATCTTCCAGAGAACGGCATTGAATTGTGCGATAATGATGAGGTCGAACCGCAGACGGCTGACGATATAAAAGAGGAGGAATTCACCGAAGAAGCAACTGTAATTCAGCCGTCAACACGAGCAGTATCTAAAAAAACATCTGTAGCGGATTCAAGTAGCATTGCTTTGGGTGCCCAGATCTATGAGGAGCTTTTGAGTGAATATCAGGCAAAGGAGAAGACTccacaaacaaagcaaaagatggcagcaacaacaatcccAAACACCCAGTCGACAAAGAAAAGGAAACAAACACCACGGGAGCCAGCTCTCAAACGTACCAAACAAACGAGAGAGGAGAAAAATCGGATACGTCGTGAACAGAATAAAGCTTTGCCCCGCAATCATGTGTGCGATCAGTGCGGTTCATCCTTTCGATTTAGATGCAATCTCACACAACATATGCTGCGGCACACGCGCTCCAAGAACTATCCATGTCCGGAATGCCCCAAGCAGTTTTATGATGCCTATATGAGAAACATGCATATCCGTGTGAGTCACCGAGGCGAACTTCCCTTTGTCTGCAATTATTGTCCGAAAGCATTTAAAGCTTCTAGCTTACGTTATCTGCACGAGaaAAACGATCATGGAGCATCTCCGCGCATTCACAGgaatgtaaataaatcaaacaaaggGATAGGACTCAAGAAAAGTCAGACGCAGCCAGAGTCAATTGTAGATGAAGATGGTCGTCATTGTTGTAGTTATTGCGATAAAAGCTATGTCACAAAATGCGCGCTCAAATTCCATATTAATCAACATTTAGGCCTGACTCCTTACAAGTGCAAGCTCTGCGATATGAGGTTTCCGAATCCTCTAGCGAAACAACGTCACGAGATGAGGCACGATAGTAAGCGTCCCTTCGAATGTGACATTTGCCTCAAAGGATTCTACACACGGATTAATCTTAAAAATCATGAACGGATTCATACTGGCGAACGCCCTTACAGGTGTGACATTTGCGATTCCTTTTTCCGATACAAGTTCAACTTGCATTCGCATCAGTTTAGCAAAATGCATAAGGATAATCTGCTAAGGGCGCAAAAGGAGAAAATTGTCGAAGACTCAGGTTCATCGTCAGAATGA
Protein Sequence: MGFPRSIKNEREKLKKHKNKKLVAELLEEAEVREAAVPNFVSSTENAFVPFTSASSENDPLAEEQVKADNAPTSYENDVTLANKMKCRTCFRPFVVDDNAKDLSNVENAVMLYHIEFITGIWIQCNDEISQFMCSHCVDNLSTAIEFRETCIRTELLLTGGDDVDLPENGIELCDNDEVEPQTADDIKEEEFTEEATVIEPSTRVVSKKTSVADSSSIALGAQIYEELLSEYQAKEKTSQTKQKMATTTIPNTQSTKKRKQTPREPALKRTKQTREEKNRIRREQNKALPRNHVCDQCGSSFRFRCNLTIHMLRHTRSKNYPCPECPKQFYDAYMRNMHIRVSHRGELPFVCNYCPKAFKASSLRYLHEKNDHGASPRIHKNVNKSNQRIGLKKSQTQRHCCSYCDQSYVTKCALNWHINQHLGLTPYKCKCCDMSFPNPQAKQRHEMRHDSKRPFECDICLKGFYTRIKLKEHERIHTGERPYRCDICDSFFRYKFNLHSHQFSKMHKDNLLKAQKEKIVEDSRFPRNNKNEREKLKKHKNKKLVAELLEEAEVREAAVPNFVSSTENAFVPFTSASSENDPLAEEQVKATTSYENDVTLANKMKCRTCFRPFVVDDNAKDLSDVENAVMLYHIEFITGIWIQCNDEISQFMCSHCVDNLSTAIEFRETCIRTELLLTGGDDVDLPENGIELCDNDEVEPQTADDIKEEEFTEEATVIQPSTRAVSKKTSVADSSSIALGAQIYEELLSEYQAKEKTPQTKQKMAATTIPNTQSTKKRKQTPREPALKRTKQTREEKNRIRREQNKALPRNHVCDQCGSSFRFRCNLTQHMLRHTRSKNYPCPECPKQFYDAYMRNMHIRVSHRGELPFVCNYCPKAFKASSLRYLHEKNDHGASPRIHRNVNKSNKGIGLKKSQTQPESIVDEDGRHCCSYCDKSYVTKCALKFHINQHLGLTPYKCKLCDMRFPNPLAKQRHEMRHDSKRPFECDICLKGFYTRINLKNHERIHTGERPYRCDICDSFFRYKFNLHSHQFSKMHKDNLLRAQKEKIVEDSGSSSE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -