Basic Information

Insect: Drosophila suboccidentalis
Gene Symbol: Znf574
Assembly: GCA_037043435.1
Location: JBAMBK010001482.1:306787-309008[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.074 5.4 7.9 0.8 2 23 332 354 331 354 0.96

2 10 2.7 1.9e+02 3.0 0.2 6 23 364 381 364 381 0.97

3 10 1.6e-05 0.0012 19.5 0.9 1 23 387 409 387 409 0.98

4 10 0.0007 0.051 14.3 0.8 1 23 420 443 420 443 0.90

5 10 2.4e-05 0.0018 18.9 0.9 1 23 451 474 451 474 0.97

6 10 2.1e-05 0.0015 19.1 1.1 3 23 482 503 480 503 0.92

7 10 0.0074 0.54 11.1 0.4 2 23 515 537 514 537 0.97

8 10 3.9e-05 0.0028 18.2 2.8 1 23 544 567 544 567 0.93

9 10 2.7e-06 0.0002 21.9 1.2 1 23 573 595 573 595 0.98

10 10 6.5e-05 0.0047 17.5 1.4 1 23 601 624 601 624 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.074	5.4	7.9	0.8	2	23	332	354	331	354	0.96
2	10	2.7	1.9e+02	3.0	0.2	6	23	364	381	364	381	0.97
3	10	1.6e-05	0.0012	19.5	0.9	1	23	387	409	387	409	0.98
4	10	0.0007	0.051	14.3	0.8	1	23	420	443	420	443	0.90
5	10	2.4e-05	0.0018	18.9	0.9	1	23	451	474	451	474	0.97
6	10	2.1e-05	0.0015	19.1	1.1	3	23	482	503	480	503	0.92
7	10	0.0074	0.54	11.1	0.4	2	23	515	537	514	537	0.97
8	10	3.9e-05	0.0028	18.2	2.8	1	23	544	567	544	567	0.93
9	10	2.7e-06	0.0002	21.9	1.2	1	23	573	595	573	595	0.98
10	10	6.5e-05	0.0047	17.5	1.4	1	23	601	624	601	624	0.97

Sequence Information

Coding Sequence: ATGGCCGCCTGTGTGCTTTGCCTTGGATGCTGCAAAGTAGGCGAGTCGTACAAGATATTCTCCGAGGCAGGTTTGCGACTGAACATTtgccaaacaataaacaaacatttctgGCTGGAGTTGAACAGCGCGGCCGGTGAAGATGAGGAAGTTTGCCATCAGTGCTGGGAGTGTGTTAGCAACTTTAATGAGTTTTACCAGGGCGTCTACAACACGCACCAGGAACGACGCGAGGTCAAGAATGTGCCCATCGATTTCTGCGCCGAGCCGGGCGCAACTAATCCGCTTGCCCTGGGAGCTGAATTGGATGCACTGGCGGAGGATTTCTTTGCGTCTGGCAATGTCAAGGTGGAAGTGAACGAACTGGAACCACTGACCAAGCTGGAAGTCCTCGAGCAGCCAGTGATTGAGGAAACGAAAGCCACAAAACGCGCCAGTGCCGATATTCCAACAAGTGCAAAGCGTCGCATTAAGAAGGAGAAACCGACCATACTTAGTGACTCCGATGGGGATGTACCACTCGCCGAGTTCCTCGACCTGAAGAAGGCTGGGAAACCAACGGCATCCGGGGATGATCAAACGGCTGCCAAGGGAAGACAATTGCGTCGGAGCTCGCGACGTGGCTGCAGGGCGAAAACATCGCCCGAATCAGCTccagcaaaattgaaaaaggaGTACGTATCGGACGAGGAGCtggacaatgacaatgacaatgacatgGACTTCGCAGCTCCCGAGGCCGTGCTAGGCACCGATGACAGTGAAAGTTCCAGTGAGAGCAGCGACAGTGAGTCTGGGGACAGTTTGCCCGACGTCGAGCCCGAGGAGCGCTACGCGGAGATTCCCAAACGCGTTGTGGTCAAGCCCAAGAAATACCGCAAACGTCAGAAGCCATTGGTTCCTCCCGTGCGCATGAGTCGGGAGGAGATTGAAAAGCGCAAGGCTCAACAGAACGAATACGATGAGATTATATTCGACTTCTTCAAGAAACTGCCATGTCACATATGCAACCTGCTGGTGCAGAACTTCGGAGACATGCGACGCCATCTGCGCATGACCCACAACATTGAAAGCGGATTTATAGCCTGCTGTGGTCGCAAGTTTCACATACGCAAAGGTCTCGCCGAGCATGTGCTTGTCCATAAGAATCCCGAGCACTTTATGTGCACCCAGTGCGGTCGTGTGTTCCAGGACTCGAAAACTCTGGAGACGCACGAACAGACGCACGCCAATCCCCAGGCACAGGACAAAACGATGTACCCGTGTGAAAAGTGTCCCAAGAGTTTCACCACGAAAGCAGCTCGCGAGTATCACAATTTGTCCAAGCATGTGCCCAAGTCGGACTTTAAGTACACCTGCCCCGAGTGCAACAAGAAATTGCCCACGGCGCGTAAACTGAAGCAGCATCTGCGCTACATGCATGATCCGGAGAGTGCCATCATCTGCGACAAGTGCGGCAAAACGCTGCGCACTCAGGCGAATCTCAAGAAGCACCACGAGCTGGAACATTCCGATGCGCCGCGTCCCAAGCCAGATCCGGTGCAGTGCGAGATATGCGGCACCTGGCTGCGCCACATGTCCGGTCTCAAGCAGCACATGAGCACCGTGCACGAGCCACCCGGCACCGAGCATCGCTGTCCCATCTGCGACAAGACATCGACGAATGCGCGAGCTCTGAAGCGACACATTTACCACAACCATCAGTGCGAACGAAAGTTCCGCTGTACCATGTGTGAGAAGGCCTTCAAGAGGCCGCAGGATTTAAGGGAGCACACATCCACGCACACGGGCGAGGTGCTGTACACCTGTCCCAACTGTCCGCAGACGTTCTTCTCCAATGCCAACATGTACAAGCATCGCCAGCGTTTGCATCGCGCCGAATGGGAGGCGGATCGCAAGAAACCTCTGCCGCCCAACATAATGAAGCAGGCGTCGTCGGCGATCAAGAAGCGACAGGTCATCACCATCACCACTGGCCTGGGCGTCTTTACACAGTCCACTGACCTGGCTGAGGGTGTCCACAAACAGGAGCCTCAGCTGCAATAG
Protein Sequence: MAACVLCLGCCKVGESYKIFSEAGLRLNICQTINKHFWLELNSAAGEDEEVCHQCWECVSNFNEFYQGVYNTHQERREVKNVPIDFCAEPGATNPLALGAELDALAEDFFASGNVKVEVNELEPLTKLEVLEQPVIEETKATKRASADIPTSAKRRIKKEKPTILSDSDGDVPLAEFLDLKKAGKPTASGDDQTAAKGRQLRRSSRRGCRAKTSPESAPAKLKKEYVSDEELDNDNDNDMDFAAPEAVLGTDDSESSSESSDSESGDSLPDVEPEERYAEIPKRVVVKPKKYRKRQKPLVPPVRMSREEIEKRKAQQNEYDEIIFDFFKKLPCHICNLLVQNFGDMRRHLRMTHNIESGFIACCGRKFHIRKGLAEHVLVHKNPEHFMCTQCGRVFQDSKTLETHEQTHANPQAQDKTMYPCEKCPKSFTTKAAREYHNLSKHVPKSDFKYTCPECNKKLPTARKLKQHLRYMHDPESAIICDKCGKTLRTQANLKKHHELEHSDAPRPKPDPVQCEICGTWLRHMSGLKQHMSTVHEPPGTEHRCPICDKTSTNARALKRHIYHNHQCERKFRCTMCEKAFKRPQDLREHTSTHTGEVLYTCPNCPQTFFSNANMYKHRQRLHRAEWEADRKKPLPPNIMKQASSAIKKRQVITITTGLGVFTQSTDLAEGVHKQEPQLQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00610837;
90% Identity: iTF_00585399;
80% Identity: -