Basic Information

Insect: Drosophila suboccidentalis
Gene Symbol: ZNF526
Assembly: GCA_037043435.1
Location: JBAMBK010002402.1:2981978-2983995[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.25 18 6.3 0.3 1 21 320 340 320 341 0.95

2 10 4.3e-06 0.00031 21.3 1.3 1 23 349 371 349 371 0.99

3 10 0.0033 0.24 12.2 1.5 1 23 374 397 374 397 0.92

4 10 1.5e-06 0.00011 22.7 0.8 2 23 404 425 403 425 0.98

5 10 2.5e-07 1.9e-05 25.1 0.6 1 23 431 453 431 453 0.98

6 10 5.4e-06 0.00039 20.9 0.7 1 23 459 481 459 481 0.99

7 10 0.00056 0.041 14.6 4.0 1 23 487 509 487 509 0.99

8 10 0.00064 0.047 14.4 0.3 1 23 515 537 515 537 0.98

9 10 0.00013 0.0092 16.6 3.7 1 23 543 565 543 565 0.98

10 10 0.0011 0.082 13.6 0.2 1 23 571 593 571 593 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.25	18	6.3	0.3	1	21	320	340	320	341	0.95
2	10	4.3e-06	0.00031	21.3	1.3	1	23	349	371	349	371	0.99
3	10	0.0033	0.24	12.2	1.5	1	23	374	397	374	397	0.92
4	10	1.5e-06	0.00011	22.7	0.8	2	23	404	425	403	425	0.98
5	10	2.5e-07	1.9e-05	25.1	0.6	1	23	431	453	431	453	0.98
6	10	5.4e-06	0.00039	20.9	0.7	1	23	459	481	459	481	0.99
7	10	0.00056	0.041	14.6	4.0	1	23	487	509	487	509	0.99
8	10	0.00064	0.047	14.4	0.3	1	23	515	537	515	537	0.98
9	10	0.00013	0.0092	16.6	3.7	1	23	543	565	543	565	0.98
10	10	0.0011	0.082	13.6	0.2	1	23	571	593	571	593	0.97

Sequence Information

Coding Sequence: ATGGATGTGGAGAAGATCTGTCGCACTTGCTTGAGTCTATCAGGACCATTTCTGTCCATCTATGATGGCGGCTCCGGCAGCTGTTTGGTCGACATGCTGCGCGAATTCACCAGGACCAAGCCGCGTAGCGAGGATAATTTACCAGGCAGAGTCTGCCTTAATTGCATCAGTGAAATTAACCACTGCTATTCGTTTAAACTCAAATGCGAGAATTCCAATCGCACGCTGCGACAACTGCTGCCAAATGTCCTGCCCGAGGAGCCCGACTATGGAACAGGAGCGAAGCCAACGGTGGCAACAACAGATTCATCAGTCCAAACAGAACTTGTCACCACATGCACAACGGAAGCGCAAACGGATGAGGTGCACACAGCAGATGCAGAGCAAAACACCAGCATGGAGAAACCTGTGGCAATCTGTGACGAGCCAGAGGATGTAGAAGAGTTTGATTATGAGTTTTCCGATGAGCACGAGAACGACGAGATGCCGTCCAAAGTGAGCGCTGAAAACATTATACTGCATGTGGAGAAAGACGACATCAAGTATGAAACGGAAATGATCTATGACAAGAGCACGGGCGAGCTGCACGAACAGCAGGGCAAAGTTGTTCCCAAACAGAAGGAGTACAAATATCGTCTGGTCAGCAATGGCAGTGGGGACACATACATTGCTCCAGAGCCAGCGCCGACACTTACTCAAGTGACGACACGCAAGAGCGCTGCCAagttgttgcagcagcagcaacaacaacagcagcagcaggaggaacCTTATCAGGATGATAATCCACAGAAATCGGAGCAGCAGGAAGCACAAACAACGAGCAAGCGCAGCACAAGACGTCGGGCTGCAGCACAActggaggaggagcagcaggaATCACCAGTCAAGCAACCAAAACGAAGTGTACCCAGTCAATCCATTAATGCATCAGAGACAGAAGATCTTAAGGCGAATTTCCACTGTGATCGCTGCAATGCCGGGTTTGTCCTGGAGAAATCATTGGTTATCCATCGGCGGCAAAATGGTTGCACCAATCGCAGTTTCAAGTGCAATGAATGCGAGCGAGTTTTTGTCTCCCTGAATCATTTGACGGAGCATCAGGCCACGCACGCTGCCCACAATTGTCAGGAGTGCGGAGTGCGGTGTGAGTCCAAGGAGCAGCTGGGCAGGCACATGGTCCAGGCGCACAAACGCAATCTGCGAAATCAGTGCAACGTTTGCCAGAAggTGTTCACGATGCTTTCAACGTTGCGGGATCACATGCGCATCCACACTGGCGAGAAGCCATTTGTGTGCAACGTATGTGGCAAGGGCTTCACACAGAATGCCAATCTGCGTCAGCACAAGCTCCGGCACTCGGACATCAAACGCTTCAAATGCGAGCTGTGCAATAATTCATTTGTGACCAAGGCGGAGCTGACTTCGCATGCGCGGACACACACAGGTGTCAAGCCGTACGAGTGTGATGTTTGCTCCTCGCGATTCACCACCAGTTGCTCATTGGCCAAGCACAAGCGCAAACACACAGGCGAACGGCCCTATCCCTGTGATCTCTGTCCCATGCGCTTCACGGCCCTCAATGTGCTGAAGAATCATCGACGCACGCACACTGGAGAGCGACCATTTGTTTGTCCCTTCTGCTCCAAGAGCTTCACACAGCGTGGCGATTGTCAAATGCATCAGCGTACGCATCAGGGTgacaaaatatacatttgtCCAGTGTGCAGTGAGGAATTCAAGTCCATGAATGATATGCGATCACATTTGACAATACATGAGCAGCAGGACAAGCGATTGGTGCACTTTACCCTCCTCAGCAACAAGGAGAACGGAAATGCGACGACGCTAGAGGAGCGGGATGATGAGTCGGATACAGCGGACACTGACTTGATGTAA
Protein Sequence: MDVEKICRTCLSLSGPFLSIYDGGSGSCLVDMLREFTRTKPRSEDNLPGRVCLNCISEINHCYSFKLKCENSNRTLRQLLPNVLPEEPDYGTGAKPTVATTDSSVQTELVTTCTTEAQTDEVHTADAEQNTSMEKPVAICDEPEDVEEFDYEFSDEHENDEMPSKVSAENIILHVEKDDIKYETEMIYDKSTGELHEQQGKVVPKQKEYKYRLVSNGSGDTYIAPEPAPTLTQVTTRKSAAKLLQQQQQQQQQQEEPYQDDNPQKSEQQEAQTTSKRSTRRRAAAQLEEEQQESPVKQPKRSVPSQSINASETEDLKANFHCDRCNAGFVLEKSLVIHRRQNGCTNRSFKCNECERVFVSLNHLTEHQATHAAHNCQECGVRCESKEQLGRHMVQAHKRNLRNQCNVCQKVFTMLSTLRDHMRIHTGEKPFVCNVCGKGFTQNANLRQHKLRHSDIKRFKCELCNNSFVTKAELTSHARTHTGVKPYECDVCSSRFTTSCSLAKHKRKHTGERPYPCDLCPMRFTALNVLKNHRRTHTGERPFVCPFCSKSFTQRGDCQMHQRTHQGDKIYICPVCSEEFKSMNDMRSHLTIHEQQDKRLVHFTLLSNKENGNATTLEERDDESDTADTDLM

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00537661;
90% Identity: iTF_00586111;
80% Identity: -