Dsub018544.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila suboccidentalis
Gene Symbol
hang
Assembly
GCA_037043435.1
Location
JBAMBK010002656.1:245458-262695[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 18 0.41 30 5.6 1.0 3 23 530 551 529 551 0.93
2 18 0.52 38 5.3 3.2 3 22 658 677 656 677 0.89
3 18 0.00089 0.065 14.0 3.3 1 22 788 809 788 811 0.90
4 18 0.1 7.4 7.5 0.1 2 21 823 842 822 843 0.93
5 18 0.001 0.075 13.8 0.2 2 23 978 1000 977 1000 0.95
6 18 0.003 0.22 12.3 0.1 1 23 1008 1031 1008 1031 0.96
7 18 2.4e-05 0.0017 18.9 0.1 2 23 1117 1138 1116 1138 0.97
8 18 0.00042 0.031 15.0 2.9 2 23 1256 1278 1255 1278 0.97
9 18 0.033 2.4 9.0 0.2 2 23 1287 1309 1286 1309 0.95
10 18 0.0011 0.08 13.7 0.2 1 23 1322 1345 1322 1345 0.97
11 18 0.00018 0.013 16.1 1.1 1 23 1387 1409 1387 1409 0.99
12 18 0.0029 0.21 12.4 0.9 1 23 1417 1440 1417 1440 0.96
13 18 0.1 7.3 7.5 0.4 2 19 1448 1465 1448 1466 0.94
14 18 0.00011 0.0078 16.9 0.4 3 23 1560 1580 1559 1580 0.98
15 18 0.0074 0.54 11.1 0.1 1 23 1615 1637 1615 1637 0.97
16 18 0.00088 0.064 14.0 0.6 2 23 1731 1753 1730 1753 0.93
17 18 0.0095 0.69 10.7 0.3 3 23 1809 1829 1809 1829 0.98
18 18 0.0001 0.0073 17.0 2.1 1 23 2242 2264 2242 2264 0.99

Sequence Information

Coding Sequence
ATGAATCTCATATTAGTAAATCCCCATATGCCAGAAGGCTTCTGCTCTACGTCGCCTCTGTATCCAATTGCGATTTTGCCGCCATCATCGTCGCCACTTGAGAAAGAGATGTGCCCAACAGGACGTCGctgtATCACGCCATTGGATCGCCTGTCGCTGCATATTTGTCATGCCTGCATCAGCTATTTGAACTCTTGGCAGAGCTTCAAGAATCGCTGCCTCAGCTCGCAGTCGAAGCAGCGGCAATGGGTGGACATGGACAGAACCAAACAGCAGACACTATTGGGCTATTTGGATTTGAATCGGGCCGAGAATGGCAGCATTGTtgaccaacagcagcagcaatctgAATTGAAAATCGATACGGCAACATCTGCGGCTGAGAAGGCATCCGCCAACATTTTGGATGGCATACCCTCGCTGAAGAAGCGCAAATCGTTAACAGTCTATGTGAGTCCAAAGCAACAgcttcaacagcaacaacaacaacaacaacagcttcaacagcaacaacaacagcagcagcagcagcaacaacaacagctactaCTGCAAACGGCAAGAACGATGGGCGGGGCAGCGGAGCCACAGCAAACATTGCAGAACCTTTTATTGCAGGTGCCCATAGCGGCGACAATGGCAACGATATcatcacagcagcaacagcaacatcagcagcagcaacagcagcgcaaatatcagcagcaacaacaacgtggcAAGCAAAAACATCACCATcattatcaacaacaacaacaacaacaacatcatcatcaccatcatcatcaacgacagcagcagcaacaacaacagcagcagcaacatcaacaacaacaacaacagcagcgacataGACGCACTCGTCAGCCCAGAAGACAGTCGCAGCagacagcaactgttgctcagCGTTTGACCAAATTTAAGCCAAAAGTGTATTTGCCACTTGACATTTCAGTGCCACCGCTGCCGCCACTGCTGCCGACGTCAActtcaactgctgctgctgctgctgctgctgcaactgcaactgttgctggtgttgctgaGGCGTTGCCATTGGCGTTGCCGTTGTCGCAGCCAATTGATTTCAGCCAGTGTAAGAATTCGAGTCAGAGTCAAAGATATGGCAGCGTGTTGCCCCCGCCGCCACCAGTTGCAACAATGGGCAGCAACGTCgtaacagcaactgcaacagctgcTCCCGCTGCTACTGCTCCCgctgcatctgtatctgccACTGCTACTGCTACTGTCACTGCCTCAGGCTCAGGCACAGGCTCAATCTCAGGCTCTGCTGCAGTCACAACTCCGCTGCTCATGCCGCCGCTGCCTGCCATGCCCATCAAGGATGAGCCATTGGATGACACGGACGATGACTTTCAGATGAAGTGCATTGACGAGTCCGACGATATGATGGATCCCACCATGTTCCTAGAGCGCTCCGAGCACGAGGGCGATGTGCCACTAATGACCTCCGACTATGATTATACGGCGCAGCATGGCGTGACGGCGGCCGTGGCAGCAGCATCGCTGCCACCAAACGCTGTGGCCAATGTGGCAGCCGCTGGGGACTCGAAGGTGGCCAGTTGCCGGGCCTGCAGTCTGCAGTTCTCGACCCGAGCGAATGCGCGTCGCCACGAACGGAACTTGCATCCGAATCTGTTCCAGCTGTCGACAGACTCGCCAAACAATACGCCAATCACAAAGCCGACGCCGGCACTGGCAGCCGCATTGGAAATCCAACGTGCGGCCGCCGCGGCAGCGGCCACAGCGGAGGCAACTAAAGCGGCAGCCGGCGGCAACATATCGACGCAGAAGTACCGCCAGGTGGTCATGAACACGTTCATCAAGTGCGAGAACGGCGGCTATGACTACGACAATCCGGAGCAGTATCAGCAATTGTTGGGCCGCGACAAGGTCGAGTTCATCCAGGAGAATAACGAGTTTCTCGAGCAATATCAAACGATGACGTGTCGATGTTGCAACAAATACTTTAGCACCTATAAGAACTTTATGGCGCACGTGCGCAAGAAGTATCCATTGCTGCCACGCAACCTGTGCTTCAATTGCCTCAAGATGAACGACTCCAAGGCGTTGTTCATATCGCATCTCAAGAAGCGCAACTGCATCAATTTGTATCGTGTGCTCAACGCGTTGCGACTCAAACAGCCAAATTTTGCCCATGCCACGACATCCGGTGTGGTTGCAACCACTGAGCCGCCGCAGcagatgcaacaacagcagcagcagcaacagcagcagcagcagcagcaacaacaattggtgGTAACATCGCATGAAACATCAACGTCGGAGCGACCGGAGAAGCTGCGTGCCAAGGAGCTGCTGGTGAATAAACTGTACGAGTGCAAGCTCTGTCCGAAGGGATTTCGCACGAAGCACGAGTTCCGCACACATGTCTACGATAAGCATGCGGATGTGCAGCGCAAGGATAACAATTCGATACAGTGCAGCTTCTGTGGGCTGGACTTTGCCGATCCGGTGGATCGGCGACGTCATTACAATAACATGGACTGCATTGTCCGTTTGCGCTGCATGACCTGCGATGCCAAATTGGAGACGCATCAGCGTTTCCTCGACCATGTCTATCAGGATCATTTGGGCGGTGCAGTGAGCAGTGATAATGCCTCGACAGCCAACAGCGTTATCGATCATTCGCCGGGGAAGCGGAGTCTGCTCGGTGCccttggcattggcattggtgTGAGTCAATCCTCCAATGATGAAtcccgcagcagcagcaccaacaacaatgccGCAAATGCACCAATAACATCCACACCGAAACtaccaacagcaacatcagcgaTTGGagctgctgcggctgcggctgctgctgcaaccAGTGGTGGCTCCACATCTGGCAGTCGAGATGCACCCAAATCCCAGTATTTCTCCCGCATGCCGCAGGTCTGCCCCATTTGTGGCCAACagtacaacaactacaacaacgtGCTGCGCCACATGGAATCGAAGCATCCAAATAAACTGCCCGAGACATACAAGTGCGTTCGATGCGGCTTGGGCTATCCAAGGATCTCATATCTGCGCGAGCATATGATCAATGTGCATGGCGTGGACAAGAATCGTCATTCCGGCGGCTTTGAGTACATTGTGAATGCGGATGCCGTTAAATTGGCCGATGGCAGCACACCAAATGTCTACACTGGACGCTATGATTATGTGATGAAGGATTTGATGTCCATAACAAATGGTGGGACACTcgATGATGACGAGGATGAAGGCGGCAGCATTGCCAAAAAGATGCGACTCGAcgatagcagcaacaacagcagcattaACACAAGCATCGCCAATCAGCAGAAGGAGTGTCCCATTTGCAATGCCGTGTTTAGTAATAATATTGGATTATCGAATCACATGCGATCACATTACACGGCCTCATCGACGGCAACGAATGCAGCATTGGCGGCTGCCAATCGAATGACGCCCAAGTCGTTGACAATTACAGCAACGCCGCCACTTGAGGtgacagccacagccacagcaacgacggcgacagcaacaacatcatcttCCTCCGCAAgcaacgcagcagcagcaacatcagcaggaACAACAGCGACGCCAGtaaacacaacagcaacagcaactacaataTCTGCGATAACtgcaacgacgacaacgaaaGTGCCACCGGCAATGGTGAATCAAACGCCACAGGAACAGGCCGTATTCCGTCGCAGCTTGGATCAAGCGGCTGATCGTCGCTTCCGTCGGATGCGCTGCCGCATCTGTCAGCGTAGATTCAGCTCGAAGAAGTCGTATCGCTATCACATGCTGACCGATCATCAGGTGCAAAATGTGCAGTTCATCAAATGCAAGCTGTGCAACGCCGAGTTTGCCTACGAGAAGGGATTGAAGGTGCATCTATTCAAGGTGCACGGACGTGCCATCAAAGATGAGATGATTGTCAAACAATTTGAATGTGATGTCTGCTCCATTGTGTACAGCTCGGAAATGGAGCTGAAACAGCACAAACGCAGCGTTCACAAGTCACAATTGGGCTCGAAATCATTAgcattattatcatcatcatcaacaacagctACTGCTACCTCTGCTGACCTGGCCGAAACATCCGCTAGTGCGTTAGCTGCCCTGCCATTGTATTGGTATCAGTGCAAGTATTGTCCATCCAACTTTAATACCAACAAGAAACTGGCCATCCACATCAATTCCCATGATGAGTTCGATTCCAATGATTATTCCTGCAAGGATTGTGGCAACGTCTACAGCGGACGCAAGAGCCTCTGGgTGCATCGGTATAAGAAGCATCCGCAGGTGCCGGACCCGGCGGAGTGCACGCTGTGCCGCAAGATGTTCTTCGATCGCCAGATGCTGGAGAATCACACTCCCACCTGCAATCGCAAGCCGATTACGGCGACGGGAGCACATCAGCAggatcaacagcagcagcaacagttgcaattgcaacagcagcgtGGCATATTCAAGCACAAGACGGGCGACGATGACGaagaggacgaggacgagatGATGTTAGATgatgctgctggtgctggcaATGTTGCCAGCGATGGCAGCAATGGTGGCAACACCGTGGCAGCTGTCGCAAGCAACACAAACACGATCAGTACAAGCAGCTTCAAGATACGCATACCAGAGGTGGCATGCACCATTTGCGGGGCACGTTTCACCGATCAGGAGATGTTTAGCAAGCACATCCAGAAGCACGAACAAGAGCTATATGTGGACAATCCGTTGGCAGCCATGTTCGATGATGGCCCAGCCGATGCGGGACAATTTCAGGTGGAGCGTCAAAATGAGAATGGGGAATATGCGTGCGATTTGTGCGCCAAGACTTTCCCCCAGGTGATTGCGCTCAAGGTGCATCGCAAGTGGCATTTCAGAGGTGATAGCAAGCAGAATCCCATCATCGACGGCGAAGCGACAATGctgaacaacaacaccaacaacaacaacaacagcaccaccagcagcaacagcaattcgATGTTGCATCTACGCGAGTTGCATGCGGTGGGTCTGATGcccaatcaacaacaacaccagaagcagcagcagcagctgcaacaacaacaacagtcccagtcgagcagcagcaacaacaacaccagcaacagctCATCGACCAGCAAATCGATGAAACGGAAACGTGAATTGAAATGCGAATATTGTGCCTCAACATtcattagcaacaacaacctgcGTCGCCACATGTACGAGCTGCACAAACATGAGGTCAGCAATCTTCCCGAGCCGCCAGTGATTGAAGTGGATGAGCCGCTGTGTTGTCGTCGTTGCGGCGATTTACAATTTGAGACCAAGGAATTGTGGATCGAACACAAATTGGCGGACGCAAAGGTGGTGCGTCCATTTTGTCCATTCCAATGGGGCTGTGATCTTTGTGGCGAGTATTTGTCGCGCAAGGAGAAGCTCATCAATCACATTAACAATCATCTCAAGGAGGAGGTAATTGTGCCAGTTGCCAATGCAAAGACAACACTGAACTCGTcagaggcaacaacagcaacagctaaaagcacaacaacagcaaagtcAACAACTGgtggagcaactgcagcaacaacaacggcaactgcaacagaaacaacaacagcaggcaaAGGGTTAAAAGTCAAAGAGATTGAAAGCGAGAGAGGGGGAAAGTTGAGCAAATCGCGTGCTAATGATAATGTAGAGCAACAGGAAGAGGATGGGGAGGATGATAGTGATATGGATGATGATAGTGATAGCGATgacgataatgatgatgatgaggaggaggatgatgatgatgaggagaATAGCACaagcgatgatgatgacgatgatgatgatgatgtcggCGATGAGGATGACGACGAAGACGATGAAGAGGAAGATGTTGTtgcaaaacagcagcaactgttgcaacagccaaacaacaacaatagcaacaacagcaatgcaaTTGACAACGATGATGACGATCTCATTGAGGAGGTTATCGAAGAGattgacgatgacgatggcgatggcgatgtgCATGAACAACATGTTGTTGCCAGAgcaaatgcaaacaacaataaagtcAACATTGATTATACGCGCACGGGCAACGCCAAGTTGAATGGAAATGGTGGCAAAAAGGCAAAGTTGCAACATGGGCAAGTGCTGATCATGCATAGCTCcgaggaagaagaagatgtagacgatgatgatgatgatgtggaaatggaaatggcagaggctgaggcagaggcagaagaGGATGATGAAGAGGGAGTACACGTGGGGGAAGAAATGACCATTGATGATATTATTGAAGAAGATGATGGTGAGGATGATGACGATGTGGTTGGTGTTAGTGGTGAAGTTGTTGaagaggatgatgatgatgacaacgacaacgacaacgatgatcgtgatcatgatgatgttgatgaggaagaggaggaagaTGAAGATATCGATGAAGACGACGATggcgacgatgacgatggcgaCGGCGACGTTGATGTGGGCAATGGTCGTCGTAATCGTGTTGATGGTGGTCGTGATGCTGGTGAtggtggtgatggtgatggtgatggtaCATCATCATCCGAGAGCGAGTCGACAACGACAACCTCGCATTCAACTGGTGAGCGGCGTAAAAAAACTGTAGTTTCATCAGCGGCACATGGCGATGCCGCTGATCAGTCTAATTCCAGCTATACGTGTGATCTATGTCAACTTTGTTTCGATTCTCAGGAGCTTCTGCAGACACACATTAAAAGCCATTTTCTCAATGGGCCAATGGCGGGCGTCAagagcaagaacaacagcagcagcagcagtaatggcagcaacaccagcagcaacggcagcagcagcggcggcgccgccagcagaagcaacaacaacaataataataataataataatagcaacaacaataataaaagcaaaaccaaaaagtccGACTTGTTGGATGCTACAAAATGTGgcggtggcagtggcagtggcagtggcagtacaacaaccacagcaacagccacagcagcagcagcaacaacaacggcaacaacaacgacgtcgacgtcagcagcgactgcgacagcggAAGTTGCTGCAGCGAGCTTGAACTGA
Protein Sequence
MNLILVNPHMPEGFCSTSPLYPIAILPPSSSPLEKEMCPTGRRCITPLDRLSLHICHACISYLNSWQSFKNRCLSSQSKQRQWVDMDRTKQQTLLGYLDLNRAENGSIVDQQQQQSELKIDTATSAAEKASANILDGIPSLKKRKSLTVYVSPKQQLQQQQQQQQQLQQQQQQQQQQQQQQLLLQTARTMGGAAEPQQTLQNLLLQVPIAATMATISSQQQQQHQQQQQQRKYQQQQQRGKQKHHHHYQQQQQQQHHHHHHHQRQQQQQQQQQQHQQQQQQQRHRRTRQPRRQSQQTATVAQRLTKFKPKVYLPLDISVPPLPPLLPTSTSTAAAAAAAATATVAGVAEALPLALPLSQPIDFSQCKNSSQSQRYGSVLPPPPPVATMGSNVVTATATAAPAATAPAASVSATATATVTASGSGTGSISGSAAVTTPLLMPPLPAMPIKDEPLDDTDDDFQMKCIDESDDMMDPTMFLERSEHEGDVPLMTSDYDYTAQHGVTAAVAAASLPPNAVANVAAAGDSKVASCRACSLQFSTRANARRHERNLHPNLFQLSTDSPNNTPITKPTPALAAALEIQRAAAAAAATAEATKAAAGGNISTQKYRQVVMNTFIKCENGGYDYDNPEQYQQLLGRDKVEFIQENNEFLEQYQTMTCRCCNKYFSTYKNFMAHVRKKYPLLPRNLCFNCLKMNDSKALFISHLKKRNCINLYRVLNALRLKQPNFAHATTSGVVATTEPPQQMQQQQQQQQQQQQQQQQLVVTSHETSTSERPEKLRAKELLVNKLYECKLCPKGFRTKHEFRTHVYDKHADVQRKDNNSIQCSFCGLDFADPVDRRRHYNNMDCIVRLRCMTCDAKLETHQRFLDHVYQDHLGGAVSSDNASTANSVIDHSPGKRSLLGALGIGIGVSQSSNDESRSSSTNNNAANAPITSTPKLPTATSAIGAAAAAAAAATSGGSTSGSRDAPKSQYFSRMPQVCPICGQQYNNYNNVLRHMESKHPNKLPETYKCVRCGLGYPRISYLREHMINVHGVDKNRHSGGFEYIVNADAVKLADGSTPNVYTGRYDYVMKDLMSITNGGTLDDDEDEGGSIAKKMRLDDSSNNSSINTSIANQQKECPICNAVFSNNIGLSNHMRSHYTASSTATNAALAAANRMTPKSLTITATPPLEVTATATATTATATTSSSSASNAAAATSAGTTATPVNTTATATTISAITATTTTKVPPAMVNQTPQEQAVFRRSLDQAADRRFRRMRCRICQRRFSSKKSYRYHMLTDHQVQNVQFIKCKLCNAEFAYEKGLKVHLFKVHGRAIKDEMIVKQFECDVCSIVYSSEMELKQHKRSVHKSQLGSKSLALLSSSSTTATATSADLAETSASALAALPLYWYQCKYCPSNFNTNKKLAIHINSHDEFDSNDYSCKDCGNVYSGRKSLWVHRYKKHPQVPDPAECTLCRKMFFDRQMLENHTPTCNRKPITATGAHQQDQQQQQQLQLQQQRGIFKHKTGDDDEEDEDEMMLDDAAGAGNVASDGSNGGNTVAAVASNTNTISTSSFKIRIPEVACTICGARFTDQEMFSKHIQKHEQELYVDNPLAAMFDDGPADAGQFQVERQNENGEYACDLCAKTFPQVIALKVHRKWHFRGDSKQNPIIDGEATMLNNNTNNNNNSTTSSNSNSMLHLRELHAVGLMPNQQQHQKQQQQLQQQQQSQSSSSNNNTSNSSSTSKSMKRKRELKCEYCASTFISNNNLRRHMYELHKHEVSNLPEPPVIEVDEPLCCRRCGDLQFETKELWIEHKLADAKVVRPFCPFQWGCDLCGEYLSRKEKLINHINNHLKEEVIVPVANAKTTLNSSEATTATAKSTTTAKSTTGGATAATTTATATETTTAGKGLKVKEIESERGGKLSKSRANDNVEQQEEDGEDDSDMDDDSDSDDDNDDDEEEDDDDEENSTSDDDDDDDDDVGDEDDDEDDEEEDVVAKQQQLLQQPNNNNSNNSNAIDNDDDDLIEEVIEEIDDDDGDGDVHEQHVVARANANNNKVNIDYTRTGNAKLNGNGGKKAKLQHGQVLIMHSSEEEEDVDDDDDDVEMEMAEAEAEAEEDDEEGVHVGEEMTIDDIIEEDDGEDDDDVVGVSGEVVEEDDDDDNDNDNDDRDHDDVDEEEEEDEDIDEDDDGDDDDGDGDVDVGNGRRNRVDGGRDAGDGGDGDGDGTSSSESESTTTTSHSTGERRKKTVVSSAAHGDAADQSNSSYTCDLCQLCFDSQELLQTHIKSHFLNGPMAGVKSKNNSSSSSNGSNTSSNGSSSGGAASRSNNNNNNNNNNSNNNNKSKTKKSDLLDATKCGGGSGSGSGSTTTTATATAAAATTTATTTTSTSAATATAEVAAASLN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00575750;
90% Identity
-
80% Identity
-