Basic Information

Insect: Drosophila subobscura
Gene Symbol: -
Assembly: GCA_008121235.1
Location: NC:16336339-16344548[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.0027 0.16 12.1 0.6 2 23 295 317 294 317 0.94

2 9 0.011 0.67 10.1 4.6 2 23 440 462 440 462 0.91

3 9 0.0052 0.31 11.2 2.3 2 23 539 561 538 561 0.94

4 9 0.05 3 8.1 3.7 1 19 663 681 663 686 0.94

5 9 0.00018 0.011 15.8 0.2 2 23 794 816 793 816 0.96

6 9 0.0087 0.52 10.5 3.6 2 23 928 950 927 950 0.96

7 9 0.085 5.1 7.3 4.2 2 23 964 986 963 986 0.92

8 9 0.0067 0.4 10.8 0.4 2 23 1047 1069 1047 1069 0.95

9 9 0.027 1.6 8.9 0.7 1 23 1176 1198 1176 1198 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.0027	0.16	12.1	0.6	2	23	295	317	294	317	0.94
2	9	0.011	0.67	10.1	4.6	2	23	440	462	440	462	0.91
3	9	0.0052	0.31	11.2	2.3	2	23	539	561	538	561	0.94
4	9	0.05	3	8.1	3.7	1	19	663	681	663	686	0.94
5	9	0.00018	0.011	15.8	0.2	2	23	794	816	793	816	0.96
6	9	0.0087	0.52	10.5	3.6	2	23	928	950	927	950	0.96
7	9	0.085	5.1	7.3	4.2	2	23	964	986	963	986	0.92
8	9	0.0067	0.4	10.8	0.4	2	23	1047	1069	1047	1069	0.95
9	9	0.027	1.6	8.9	0.7	1	23	1176	1198	1176	1198	0.99

Sequence Information

Coding Sequence: atggaaaatgttttacaacTAAAAGTGCACTTAATATTCAAAGAAAGTTTAATTGATCGCGGAAGCGGCAGCCACTACAATTTATTCATGATAATATCATCCAAAATGGCTGCATCCATATATGCCACCCCACCGCCAGATCTGAGCAGCGAGGACACTGCTCTCTCCGATGTCTCCAACTCATCGACACTCAACACGAAtcgaagcaacaacaacaatacacatgaagccacaacagcagcagcgggaggagcaggaggaggagcagcagctggcaacCATTCACCCACAGAGCAGTTGGTCAAGGGAGGGGAGCTGGAACGGGAGCCCTCGCAGTCGCCAAAGACATTGCAGAAGCCAGCGGGAAGCAGCACAAATGAGGCAGACAATGCCGAAGATGACGAGGATGTGGCAACGGAAGCGGGAGAAGCGACAGCTGAGGGAGGAGTGGAGGatggagcggcagcggcagcggaaacggaaatggaaatggaaacggaagAGGGTGCCAGCAACATGGCGGCAATGGCCGCGGCGGCAGCCAATGCGGCAgccatgcagctgcagctgctggaagcGCTCAGCGATGCGGCCAAGAAGCGGCGCAAGCAGCACAATCCCAGTCGCCTGGAGGCGCTCAACCTGAGCGGGGCGGAGGCACAGCTCGAGGATCGCACGCGGGTGGACTATGAGGAGAAGCTGTCGAAGATGTTTCTGCCCAAGTCCATGGAGAAGCTGAAGGAGACcttcgagctgctgcagcagcacaagcaggagcaggaggagcagcagcaggaggaggagtccgAGCACATATCagaggccaagcagcagcagcagcagcagcaggagcaggatcaGCGTCGCAATCCCTATCAGACCTACTGCAAGCAGTGCGGCGAGAACTTTGAGACCGAGTTCAAGCTCAGTCTGCACATGCTGCAGGATCATCGcgagggacagcagcaggagcgggatGTCGAGCCCATGGACTTTCTCAGCTCGATCAAGGTGAAGCTGGAGCGCGAGGAGAGTCCcaatcagctgcagctcgAGCAGGACATGTCCAATGGGCATGgccgggagcaggagcaggaccaagAGCAGGAACACTGGTACAATGCCAtggcccaacagcagcaacagcagcagcagcagcagcagcagcttcacccTCATGGCTCGGCGCTGGGCCCTGCCTTTCCCTTTCCACCCGGCATGGGTCCGGCGGGttatctgccgctgctgggcaTGTCCGGATTCCCCGGGGTGGATGGACTGAATCGTCCACCGTTGCGCATCTTCAATCCGGAGGCATACTGCGAGCTGTGCAACAAGGAATTctgcaacaaatatttcctcAAGACACACAAAGCCAACAAGCATGGAATCTTTGACCCTGTGGGtgagccaacagccaacagcacttccagcaacaacaacaacaacaacacgaccagcagcaacaacaacagcaacagcggcagctccaTGAGCCACATGTTCCAGCTGCAGCGagaggcagccgcagcgccgcagccaccgccgccaccgccgccagccCCGTCCAGTGTGGCAGCCAAAGTGGATGCAGCAGCGCCCGTGGCCAACATACACTGCGACATCTGCTCGAAGCGCTTCACCAACATCTTTGCCATGCGGCGACACCGCGCCAAGCAGCACgaacaggcagcggcaggggcagcggcagattCCTCGCCCAACTCCCAGGGACAGACGCGACGCGGCAGTCCTCCCATTGAGAGTCAGTCCATCAAGCAGGAGGCAcagccagagctggagctgcaggccAGACCACAGCCGTTTCAGCTGCCCGAGGGCTTCCGCGAGGACTTCACCctcgagcaggaggagctgaactttgtgccgccgccgcgcAAGTTGCccgcgcagctgcagcagcaggcccggGAGTGCGCCTCGAGTGCGGAGAAGCTGCGCCGCTTGGGCGTACACTTCCCGGAGTTCTACTGCGAGCTGTGCCACAAGGAGTACGCCAATCGGTACTTCCTGCGCACGCACAAGTGGAAGCGGCATGGCGTGTTTGTGCCCCCGGAGGAACTGGGCAAGGATGAGGCACAGCTGAGCGGCTGGCCGTTTATGCCGCTCAATCTGATGCTGGCCaaggcagcggctgctgcctcAATGGAGCAGGCAGAACAGGAGCACGAACAGGAGCCCGAACAGGAGCCAGAGGCCGAGCAGGAGCTCAACGAACAGCCCAGCAAGCGCATCAAACTGGAGCCAGacctggaggaggagaagctgaaTGGTTCCTCCGTGATGGGACTGCAGAATCTGCAGAAATTGCAGTccatgttgcagcagctgaacGACATCAATGGCAAGCGTCCGCTGCCGTGTCACCTGTGCGGCAGGGAGCTGGAGAACCAGTACGCACTTCGAGCACATCTCATGACGGAGCATGCCGCACAGATGCAGCTGCCCATGGGCATgccactgcagctgccgcctgtCCATGGCATGTCCATGCCGCTGCCGGAGCAACAGCTGCCCCTCCACGCGctctaccagcagcaggcggggCCACAGACGCCACCGAATGCTGGTGCCAGATCCTCGCCCGGCAGTGGCGAGGAATTCAAGCAACATATCGCCGCTCCCAGTGCGAGTCCGCTGCGCGAGGGCTTCTACACGCCAGAGCGCCCggtggcagctgcaggaggaggaacagcTTCAGGCACTGTCCCCGTGCCGCCGCCGAATCGGCCAGCCTACACGATAACGCCGACGAGCAGCTACTGCGAGATATGCAACAAGGAGCTGTGCAACAAGTACTTCATGAAGACCCACATGCAGCGGATGCACGGCATCGAGATCGAGAACGGAGCGCAGATCGGCGGCGTCGTGTGCAACATCTGCAACAAGGAGCTGTGCAGCAAGTACTTCCTGCGTGTCCACAAGCACAACACCCACGGCATCATCGAGGAGGGTTccccgctgccacagccacgcgGCCAGAACGGAGTCAAGCTGGaggcggcagccgcagcggcagcagcgcagcaggcAGCGCCCGAGCAGGAGCTCAATCTGacgccgccagcagcagcggcagctgcaggagggGAAAGTAACTCTGGGGCTGCCCACGAGGTGTGTCCGCTGTGTGCGCGACAATTCCGGAGCTTCAAGTGGCTGCGCTCGCATCTGATGAACGAACACGGACCGGCGGGCGTGGAGCGACTACGCGAAATGGAGGCAACTCCAGCGGCTGCCTCTGGCCGCAGCAAGCCCAACAGTCCCACGCTCAAGATAcccaacggcagcagcagtggagctCCGCCTGCAccaccagccgcagcagccaccgcaggAGCTGTTGGCAATCCTCCGCCCAATCTCGCTCAAGCGCTGCAGAACCTCAACGCGCAGCATCTCTTCGGGCAGATGCAGCAACAGGTGCCCAAGGGCATGCAGGGcatgccaccgctgccaccactGCCAGGAATGTTCGGGGAGCAGTCCCAGCGCTTCAAGGAGTATCAGTGCTCCATGTGCCCCTTCACCACGCCCTACTACGCATTCCTCTTCATCCACGAACGCTCGCACGCGCTGCTCAACAGTGCCGATGGCATGGAGGCGTCCCTGGaggcgccaccgccaccgccagccgCTGCACGCAGCCAGGGCAAATCCCGCAGCAAGTCCAAccgagcggcagcagctccaccaacCATAGAGGATGCCGAGCTGCACGTGGAACCCACCAATCTAAGCACCTCCAAAGCCACAACCAGCCACTCTCCCACACAACACACGCCAGGAACTCCCTCACCAAAGGCCCAGTCTCCGCTGGCTGCAGGCAAGAACCGCTCACCGAATCTTACCGGACGCCGCAGCTCCAAGTCCAACACGCCCAATGGCATTGGAGGAGGCCATCGATCGGCTGCCACTTCGCCCTTTGAGGTGTGCACCGATCTGGCCAATGGCACTGGGAAACCAGCGAGCTATGCCCAACCCGACCGCTCCGAGGAAGCATATCAGATGCAGGCATTCCATCTGCAGCCAGCCGATGCCGATTCGGAGATGCAATTTGCTCCGGCTCTGGTCTATCTGCCTGTGCGGGTGCGCGCCTCGGAGACGGCCACGCTGAGCTTCAGACTAACACCAGCCTAA
Protein Sequence: MENVLQLKVHLIFKESLIDRGSGSHYNLFMIISSKMAASIYATPPPDLSSEDTALSDVSNSSTLNTNRSNNNNTHEATTAAAGGAGGGAAAGNHSPTEQLVKGGELEREPSQSPKTLQKPAGSSTNEADNAEDDEDVATEAGEATAEGGVEDGAAAAAETEMEMETEEGASNMAAMAAAAANAAAMQLQLLEALSDAAKKRRKQHNPSRLEALNLSGAEAQLEDRTRVDYEEKLSKMFLPKSMEKLKETFELLQQHKQEQEEQQQEEESEHISEAKQQQQQQQEQDQRRNPYQTYCKQCGENFETEFKLSLHMLQDHREGQQQERDVEPMDFLSSIKVKLEREESPNQLQLEQDMSNGHGREQEQDQEQEHWYNAMAQQQQQQQQQQQQLHPHGSALGPAFPFPPGMGPAGYLPLLGMSGFPGVDGLNRPPLRIFNPEAYCELCNKEFCNKYFLKTHKANKHGIFDPVGEPTANSTSSNNNNNNTTSSNNNSNSGSSMSHMFQLQREAAAAPQPPPPPPPAPSSVAAKVDAAAPVANIHCDICSKRFTNIFAMRRHRAKQHEQAAAGAAADSSPNSQGQTRRGSPPIESQSIKQEAQPELELQARPQPFQLPEGFREDFTLEQEELNFVPPPRKLPAQLQQQARECASSAEKLRRLGVHFPEFYCELCHKEYANRYFLRTHKWKRHGVFVPPEELGKDEAQLSGWPFMPLNLMLAKAAAAASMEQAEQEHEQEPEQEPEAEQELNEQPSKRIKLEPDLEEEKLNGSSVMGLQNLQKLQSMLQQLNDINGKRPLPCHLCGRELENQYALRAHLMTEHAAQMQLPMGMPLQLPPVHGMSMPLPEQQLPLHALYQQQAGPQTPPNAGARSSPGSGEEFKQHIAAPSASPLREGFYTPERPVAAAGGGTASGTVPVPPPNRPAYTITPTSSYCEICNKELCNKYFMKTHMQRMHGIEIENGAQIGGVVCNICNKELCSKYFLRVHKHNTHGIIEEGSPLPQPRGQNGVKLEAAAAAAAAQQAAPEQELNLTPPAAAAAAGGESNSGAAHEVCPLCARQFRSFKWLRSHLMNEHGPAGVERLREMEATPAAASGRSKPNSPTLKIPNGSSSGAPPAPPAAAATAGAVGNPPPNLAQALQNLNAQHLFGQMQQQVPKGMQGMPPLPPLPGMFGEQSQRFKEYQCSMCPFTTPYYAFLFIHERSHALLNSADGMEASLEAPPPPPAAARSQGKSRSKSNRAAAAPPTIEDAELHVEPTNLSTSKATTSHSPTQHTPGTPSPKAQSPLAAGKNRSPNLTGRRSSKSNTPNGIGGGHRSAATSPFEVCTDLANGTGKPASYAQPDRSEEAYQMQAFHLQPADADSEMQFAPALVYLPVRVRASETATLSFRLTPA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00603642;
90% Identity: iTF_00515184;
80% Identity: -