Basic Information

Insect: Drosophila subobscura
Gene Symbol: -
Assembly: GCA_008121235.1
Location: NC:9050263-9082671[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.041 2.4 8.3 1.8 1 23 1201 1223 1201 1224 0.94

2 8 0.0087 0.52 10.5 0.1 1 23 1229 1252 1229 1252 0.98

3 8 0.0071 0.42 10.7 2.6 1 23 1438 1461 1438 1461 0.95

4 8 0.00039 0.023 14.7 2.1 1 23 1469 1491 1469 1491 0.98

5 8 4.4e-05 0.0026 17.7 0.8 1 23 1498 1521 1498 1521 0.97

6 8 4.7e-05 0.0028 17.6 1.4 1 23 1527 1549 1527 1549 0.96

7 8 8.5e-06 0.0005 19.9 1.2 1 23 1554 1576 1554 1576 0.99

8 8 0.016 0.96 9.6 3.0 1 23 1582 1604 1582 1604 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.041	2.4	8.3	1.8	1	23	1201	1223	1201	1224	0.94
2	8	0.0087	0.52	10.5	0.1	1	23	1229	1252	1229	1252	0.98
3	8	0.0071	0.42	10.7	2.6	1	23	1438	1461	1438	1461	0.95
4	8	0.00039	0.023	14.7	2.1	1	23	1469	1491	1469	1491	0.98
5	8	4.4e-05	0.0026	17.7	0.8	1	23	1498	1521	1498	1521	0.97
6	8	4.7e-05	0.0028	17.6	1.4	1	23	1527	1549	1527	1549	0.96
7	8	8.5e-06	0.0005	19.9	1.2	1	23	1554	1576	1554	1576	0.99
8	8	0.016	0.96	9.6	3.0	1	23	1582	1604	1582	1604	0.99

Sequence Information

Coding Sequence: ATGagtgccaacagcagcagagtcagGAGGCGCAGCAATAGCTGGTCGTCGGTAAAGCAGCCGGCGGCGCAACTTTCTCTGCCGGCAGACGATGACGTCGCAGGGGGAAATGCTGGAAATTTGCTGGAAATGCCCCGCatatgccgctgctgctgcaaacgGGATTTGGAGCTGCTTAACCTCTTTGGGGCCGACAAACCAACCATATCCTCCACAGACATGGGGAtggagacagacacagacacatctACGATGCGACGCCGCAGCACCACCACATCCACGCCGCTGGGGGATCGCACCAACGGTAATCCCGTAGACTACGCCCTGAGCGGCGCCCACAGCAGCATGGACATTGTCCTCGAGGAGATGATCATCTGGATGCTCAATGTCAGCCGCGACGATGGACTTCCGCAGGAGATCTGCCGCCAGTGCATGGCCCAGTTCCTGATGGTGGCCAAATTTCGTAGGAAATGCGTGCGGATGCAGCAGCGCCTGCAGGACTATGCCCAGGAAATATCCGACCgacaggcagccagacagGCCAAGcggagacagaggcagcagcaacgacaggAACTGCAGAACAGACCACAAGCAGACAAGGAAGCCAAGGACACGGATGCCATTAAGGATGCGAATGCATCGGACTACATGCATTTGCCAGAATCACAGATGGACCGAAAGCGTCGCATTATCTCTGAATCTGAGGGCGGAGCTCCGTCCCCTTTGCCTTCCCTGCCAAAAATTGTGAAGACGGAAGAGTCCATCACGGAGGAGTTTCTGCCCGAGGGACGTCGCTTGCAGCAGAGATTGCGCAGAATGCGCACAAAGTCCGCGGGCACCCCAGCATCGTCTGAGAATGCAGAGGAAGAACCGCCCGTCCGCGCTGATCGCAGGAGCATGCCCTGGAAGACAAAGGcggccaggaaacagctgTCCGAGTCGTGGTCCAGCTACTCGCCGGCCCCCTCCTCGGAGGTGGAGGGCCAatggagcaacagcagtgaGGCGGCCACAGAAAATCTGAGCGATCTGTCGGTGGATCCACTCTGCGGATTCGAGAGCGACAGCAATCCCTCCTCCACCTCAGCGCCCTCGGAGCTCAAGTTCCCCAGACGAGCGCCCAAAGCGGTGCCAGCCCAGCGGCGTGGCCGTCGTCCGCGCAGTTCGCCCGTTTACATGGCAGCCAAGCGGCAGCGGCGATCAGTGAGCAAGAAGCCGACCATGAAGGAGCTCCTGCAGCAGATTGGAGCCAGTGTGGAGGAGAATACAAAGTCTGAGGATAAAATCTGCTGCCAAAATCCAAAGGAAGAGCAGTACGAAAACGATTCGGTGTGTCCAGTGGCAAAGTCTTCCTCCAGTGATGAGGATAGCGACATCAGTACTTCAGATGCAGGAGAATCAACCGTAGGGATCGAAGAagtaaaagaaacaaatggCAAGGAAGAAGCGGCCAAGGAGCTGCCCTCAAGGACTGAGGAATTACCGAGTGATTCTTCCGATGAGAGCAATGAGGAGGCGTCTCCGCCCAAGCTAACTAtgaaagaagaacaaaaattgaatggaGCAACCACTTTCGATGTGTCTTCGATGGAGCTACAGTCGAAGGAACTGACCTCGTCCACGGAGGCCACAGACACAACCACAAGCGCAACCAGTGAGGGGGAGCAGCTGTCGCTGGAAGCTGAAGAAGAGCCCGAGCAGGCAGAGATCATTGTGAGCATACCGCTCGAGGCACTCAATGACGATCTGCAGCGCAGATTGTGCGTGGAAAATgctgagcaggagcaggaggaggatcagcagaagaagcagcagcttccGGGAAATCCCGACGATGTCAACAACAATGCAAACGATGAGAATTTTTGCCAGAGTGCTACAGCAGATAGCTTCAATTCTGCTGTGGCACTCCAAACAATCGAAATTGAAGCAAAAGCAACTGGCCCACCCGATGGGTGCACAGCTGCAGAGCCACTAATACGCGTGGCAGAGTCCCCACCGACACCACCAGATGGGGACGAAGCAGACACCGACACCTCGGCATCCACGGATGAGATTCAAGTGGTCAGGACTGGACCCACGCCCATGGACTTTCTGGCCGAGTTCGAGAAGCATTGCGAGAAGGGTCTCGAGCAGCTGGGGGCCACCACACCCGCCTCATCGCCGCCGGCCACACCCAGGGCCGAGCCCCTGCCGCTGGCCCTCAACGATCTggaggccaagcagcagctcgagGTGGAGATGAACGATGTGGAGACGACACTGAATGGCATCCTCAACGAGATGCAGGACCAGCACATATACACACCGACCTGTCCGCACATCGATGAGTTCCTCACACCCGCCGACTATGCCTCCCTCAGCGAGCccgaacaggagcaggagccggagccaaCCGGCGACATCAAGCCAGAACTCACAGAGTCACAGGAGAAAGCCAACCCAAATCTCTTTGACAACAGCAACTTTAGCAACGAGCTGATTGGCTTTCAGAATGATATTCCCTGCTTTGAGAACATCGAGACCACGCCAGAGCCCGAGCAGAGTTTGCACTTGGAGCTGACGCAGTTTCTCAACGaactgcagccgcagccacagcaggcaGTGCAGACAGTGCAGACAGTGCAGGGGCCGCAGGTTGAGGTAATCCCAACTGAGGTAAAGCCTGTCGTTGAGCAGTCTCCGGTGCAAATACAGGTTCAGGTGCAGCAACAACCTCTGGAGCATATTCAGGTGCGTCAGCCAATAGCCTCGAAAGCCTTAGAGCAGGTGCCGCAGGTGCATCACCAGGAGACGACCACCACCGTGTCCCATGAGCAAATATatcaccatcatcagcagcattctgtccagcagcagcagcagtcggccAGCAAGCTGCAACTCGCAGCTTCCATCGatccgcagcaacagcagcaatggcagcagtaTCAgccccaggagcagcagcagcagacgacacATTTGCAATGGTCAGCAGTGGGTGGACTGGAGGCCATCAAGAGCGGCATTGGACCATTGGATGGCACCACAACAACATATTACATCAGTGCAGGGGACCTctaccagcaccagcagcagggcgcACCACTGGAGACCACGTACACGATGCTGGATCCCAATGAAAACTACATACTGGAGCAGGCCAACCatcaccaacagcagcagcagcagcagcagcaacagcaacagttgcagcaacaacagcaacagcagcagcaacccatCATGATATTGATCCAGCAGCcggagccacagcagccagtgGCCTCGTCCAGCAATCCCCAGCAAGCGCCGATGCACTTTTACGGTGCGCCCATCAGCAACGAGCTGCaccatctgcagcagcagcaacagcagcagcaacatcaacagcagcagcagcagcagcagcagcagcatcaagtaCAAAATCATTCAGTATTAGGAATGCAGagagtggcggcagcagcagcggctgcctcTCCAATGCCCGCCACCACGCCCAAGGGTCGAGCGGTGTCGCTCAAGTGCCGCTTCTGCCAGAACGGACCGAGATTCTCCAACAGTCTCGAGTACAGTCGCCACATCATCGAGCTGCATCCGGCAGTTGCGCCTTTCAACTGTCCGCACTGTCCGCTGGCCTTTGCGGCGCGCAGCAAGCGATCGCAGCACATCCTCAACCATCATGTGGTGCAGCAGTATCAGTGCGGCCAGTGCTCGCAGGTGTTTCCCGCCCAGCGAGCCCTCGACTTGCACATTCAGCGCTTCCACATGCAGGTGACCAGCAACACGGGAGGCTGCGAaaagggaggagcaggaggtgtaCGAGTGGAGGAGGTACAATTGCAGATcagcaacgagcagcagccgcagcagcagcaatcacatCCGCCAGCAAAGCCGCCAGGACCACGCAGGCAACGCATTCTCTGCTGTCCGGACTGCGAGGACTGCACCTCTGGCCACAGTCACGGCAATGGACAgtacgaggagctgcagaCTAATCTGCAGGCACCACCAACGGTGCTTACGCCGCCCTCGACGATCATGTCGGTGCCGTCTCCGCAGCCCATGATGAGCACACATCAGCACATAACCCTGCCCTCGCCCGAGCAATCCGAGCCGGACTCCACTACGACGCTGCGGCAGTTCCGTAAGCGAGGCGTCATCGTGAGCCCGCAGTCGGGGATCTTTAATCAGACGCTGCAGCTGGCCACGCCCGTGGCTTCGCCCTCACcctcgccatcgtcgtcgccgtcCTCTTCCACAATAGACACGGCGCCAAACACACCCGCGTCTGTGCAGGTCAGCGAACTGCGGGCCAGCCACCAGTGTCTGTACTGCGAGGAGCGCTTCACCAACGACATTGCCCTGCGTAAGCACCACCAGCTGGCCCATGGAGCCCAGACCTCGATGCCCTTCGTGTGCACCATTTGCAAGCGGGGCTATCGGATGCGCACGGCCCTGCATCGGCACATGGAATCGCACGATGTGGAGGGCAGGCCGTACGAGTGCAATCTGTGCCACGTGCGTTTCCCGCGACCCTCACAGCTGACGCTGCACAAGATCACCGTCCACCTGCTGTCCAAGCCGCACACCTGCGACGAgtgtggcaaacaatttggTACGGAGAGCGCCCTAAAGACGCACGTTAAGTTTCACGGTGAACTTGCTTACCAGTGCGACGAGTGCGATCTGTCCTTTGAGTATATCAGAGATTTGCGCAAGCACCGACGCACCCACAAAGGCGAATTGTTTTACAAATGCGAGTTCTGTCCACGCTCCTTCTTGCATTTTATGGGTTTCCGCGCTCACATGAACTCCCATCTGCCGCTGGGCGTGTTTCTGAACGAGGAGACCCAACTGAAGTCTTCGTCCAactgcagcaccaccagcaacagcagcatccacaaTGACAAGTCCGGCGAGAATCCAGCCACACCCAGCATGGAGGAGACACCGCTTACCCCGATGAGCAACATAAATAGTAATCCAGATGAATGCTGTCAAATCTCCAATTCGGTGGAGAGCAGCGTTTTGGTTGGGCGTAGCCTGCCTAGCCTAGACTCGATTGCCGCAACGCCATAA
Protein Sequence: MSANSSRVRRRSNSWSSVKQPAAQLSLPADDDVAGGNAGNLLEMPRICRCCCKRDLELLNLFGADKPTISSTDMGMETDTDTSTMRRRSTTTSTPLGDRTNGNPVDYALSGAHSSMDIVLEEMIIWMLNVSRDDGLPQEICRQCMAQFLMVAKFRRKCVRMQQRLQDYAQEISDRQAARQAKRRQRQQQRQELQNRPQADKEAKDTDAIKDANASDYMHLPESQMDRKRRIISESEGGAPSPLPSLPKIVKTEESITEEFLPEGRRLQQRLRRMRTKSAGTPASSENAEEEPPVRADRRSMPWKTKAARKQLSESWSSYSPAPSSEVEGQWSNSSEAATENLSDLSVDPLCGFESDSNPSSTSAPSELKFPRRAPKAVPAQRRGRRPRSSPVYMAAKRQRRSVSKKPTMKELLQQIGASVEENTKSEDKICCQNPKEEQYENDSVCPVAKSSSSDEDSDISTSDAGESTVGIEEVKETNGKEEAAKELPSRTEELPSDSSDESNEEASPPKLTMKEEQKLNGATTFDVSSMELQSKELTSSTEATDTTTSATSEGEQLSLEAEEEPEQAEIIVSIPLEALNDDLQRRLCVENAEQEQEEDQQKKQQLPGNPDDVNNNANDENFCQSATADSFNSAVALQTIEIEAKATGPPDGCTAAEPLIRVAESPPTPPDGDEADTDTSASTDEIQVVRTGPTPMDFLAEFEKHCEKGLEQLGATTPASSPPATPRAEPLPLALNDLEAKQQLEVEMNDVETTLNGILNEMQDQHIYTPTCPHIDEFLTPADYASLSEPEQEQEPEPTGDIKPELTESQEKANPNLFDNSNFSNELIGFQNDIPCFENIETTPEPEQSLHLELTQFLNELQPQPQQAVQTVQTVQGPQVEVIPTEVKPVVEQSPVQIQVQVQQQPLEHIQVRQPIASKALEQVPQVHHQETTTTVSHEQIYHHHQQHSVQQQQQSASKLQLAASIDPQQQQQWQQYQPQEQQQQTTHLQWSAVGGLEAIKSGIGPLDGTTTTYYISAGDLYQHQQQGAPLETTYTMLDPNENYILEQANHHQQQQQQQQQQQQLQQQQQQQQQPIMILIQQPEPQQPVASSSNPQQAPMHFYGAPISNELHHLQQQQQQQQHQQQQQQQQQQHQVQNHSVLGMQRVAAAAAAASPMPATTPKGRAVSLKCRFCQNGPRFSNSLEYSRHIIELHPAVAPFNCPHCPLAFAARSKRSQHILNHHVVQQYQCGQCSQVFPAQRALDLHIQRFHMQVTSNTGGCEKGGAGGVRVEEVQLQISNEQQPQQQQSHPPAKPPGPRRQRILCCPDCEDCTSGHSHGNGQYEELQTNLQAPPTVLTPPSTIMSVPSPQPMMSTHQHITLPSPEQSEPDSTTTLRQFRKRGVIVSPQSGIFNQTLQLATPVASPSPSPSSSPSSSTIDTAPNTPASVQVSELRASHQCLYCEERFTNDIALRKHHQLAHGAQTSMPFVCTICKRGYRMRTALHRHMESHDVEGRPYECNLCHVRFPRPSQLTLHKITVHLLSKPHTCDECGKQFGTESALKTHVKFHGELAYQCDECDLSFEYIRDLRKHRRTHKGELFYKCEFCPRSFLHFMGFRAHMNSHLPLGVFLNEETQLKSSSNCSTTSNSSIHNDKSGENPATPSMEETPLTPMSNINSNPDECCQISNSVESSVLVGRSLPSLDSIAATP

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00515170;
90% Identity: iTF_00515170;
80% Identity: -