Basic Information

Insect: Drosophila subobscura
Gene Symbol: -
Assembly: GCA_008121235.1
Location: NC:222132-226015[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 1.9 1.1e+02 3.1 1.6 3 23 248 269 247 269 0.88

2 8 0.00042 0.025 14.6 3.3 1 23 511 533 511 533 0.98

3 8 0.00082 0.049 13.7 2.5 1 23 539 561 539 561 0.97

4 8 0.00028 0.017 15.2 0.7 1 23 567 589 567 589 0.99

5 8 1.8e-07 1.1e-05 25.2 0.2 1 23 595 617 595 617 0.99

6 8 3.6e-06 0.00021 21.1 0.2 1 23 623 645 623 645 0.98

7 8 7.7e-06 0.00045 20.1 0.7 2 23 652 673 651 673 0.97

8 8 5.5e-05 0.0033 17.4 1.2 1 23 679 702 679 702 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	1.9	1.1e+02	3.1	1.6	3	23	248	269	247	269	0.88
2	8	0.00042	0.025	14.6	3.3	1	23	511	533	511	533	0.98
3	8	0.00082	0.049	13.7	2.5	1	23	539	561	539	561	0.97
4	8	0.00028	0.017	15.2	0.7	1	23	567	589	567	589	0.99
5	8	1.8e-07	1.1e-05	25.2	0.2	1	23	595	617	595	617	0.99
6	8	3.6e-06	0.00021	21.1	0.2	1	23	623	645	623	645	0.98
7	8	7.7e-06	0.00045	20.1	0.7	2	23	652	673	651	673	0.97
8	8	5.5e-05	0.0033	17.4	1.2	1	23	679	702	679	702	0.97

Sequence Information

Coding Sequence: ATGGTCAATGTTCCAGTGCCGATGCCGTCGGTGctgaaagcagcaaaaaaaacaaatggagaCTCCATAATGGTGGCTGCATCGAATGCGGCGGCAGCGTTGGGTGACAACGAAGACTCGGATGAGTCTGAATTGGAGGAAGATGACGATTTACTTGATGATCCTGACGATGTGATTCTACAAATCGACAGCGAGGACGAGGCCGAATTGGAGGCCCAGCGCATTCGCTTAGATGtgaaagcagcggcagccgcagctgcagcggagacagcagaaacaacaacaaagtcgCAGGTCAGTAACGGTAataagcagaagcagcaaaatcagcagcagacgaaTAACAAAGCAGCGTCACGAAAACCTCGTGGTCGTCCCCCTGGAAcgggaaacaaaaacaaacggaaCAAATCGGGTGGAAGAAACTCGAGGAGCTCCGAGGCCTCCACAGCATCCTCTCTGGTCGCCGCCGAGGTCTTGGCAGATGAAAAGTGGCATCGCTTCTTCTACAAATGTTCCCTCTGCTGCAACCAGTACAGCGACGGACTGTCTCTCTCCCGGCACTTCCAGAAGGAGCACCCGGTGCAAGACTGCCAACAGGCCAAGCGCAAGCGTGGTAGAAGCAAATGTTCTTCTATCGGAATCGAGTCACACACCCCTCTTGATATGTCGAGCTTGAATTTAGGTTATTTGAAGCCTTGTGCCCAGCTGCTGATAGAAGGGGAGTCCCTGTTGCAGCTTTGTTTGGCTTGCAACTCCCAGTTCGTGGATGTGAAACATTTTCGCCGTCATCTGAGCGAGCAGCATGGCTACTTTAAGTTGCTCGTACCTAAGGAGGAACCCACAGAGGTGCCACCCACACTTGCTGCTATAGCCATGAGCAAGTCCAGTCAGCAGTTTCAGTTGCCCATCCCAGCACCAGACACGCCACCGCCCGAGCAGGATGGCAAGGATTCGTCGGGGAATGGCTCGCGCAACGAAAAAGATGATCTCGATATATTAAACGCCATGGTGGCCAAAATGGCAGCCGTGAGGGGCAAGCAGAACTGCGTTCACAAGGTCAACAAGATGATTATTAAGCTGCCAGGTGTGGCTAAGCATGGCAAAAAAGTTAATGATCAGGCAGAATATCCTAAGCAAACGGAAAAAGAGCAGAAACGTCCAGACTACATGGAGAACCCTGAAACAAAGAACGAGGATAAGTCGGAAAAAGCAGTGCAAGATCCGCAGCAGTGTCCAGAGGAGATTGAACCAGCCAAGCGGAAACGCGCTTGCAAAAAATTAGTACCGTCATCCTTGGATcctgagaaaaatataaaaaaagagatgGAGTCAAGCGAGCGATGCATGCGCAAGACTCGAAACTTTGTCGACTATGTAATGGATTTGAAGGATGAGGAGGACGAAGACGCAGAGGAGACTGAGGGCTCCTCTGCCACAGTTTCGCCTCGAAACAGCTCGAGCGATGAGAGCCTATTCTCCATTAAACGGGAGTCAATAGAAGAGTCTCAGAGCACTGGTAGGCGCATACACACTTGCAACTTTTGCGGAAAGGCATTTCAGCGCTTCTCACGCATGCAAGATCATCTGCGAATCCACACAGGCGAGAAACCATTCACTTGTAACCATTGCGGAAGAGCTTTTCGCTTGAAGATGCGTCTTGCAGAGCATAAGTTGCGACATCGTACAGAGAAGGCCTATCAATGCGAAATATGTTCCATGCCCTTGGCCACCAAACAAGATCTATCACTGCATATGCGGCATCATAAGAATGACAGGCGGTACAAGTGCGACAAATGTGACAAAGGTTTTGTGCGAAGCTCCGATTTGGCCATCCATGTAAGAATTCATACTGGAGAAAAACCGTATGCTTGTGATCTGTGCGGGAAGGCCTTTCGGGCTCGTCAGAACCTTGTGGTGCACCGACGTACTCATTTAGGCGATAAACCGATACAGTGTGAGCTGTGCGAGAAACGGTTCGCAAGGAAGATTGACATGCGAGTGCACATGCGGAAGCATACAGGTGAGAAACCTTTTAACTGCGAATCTTGTCAGCGTGGCTACTCCTCCCGTGTGAATCTGCAGCGTCATCAACAGCGCGAGCATGGCAAAGGCTCGCAAAATGCCGTACGGAAAACGACCGGGCAAGGAAAAGACATAAAGCCAGAGGCGGGAAACGATTCCATCCCACAGAATGAAACTCAATCCAAGACAGAGCAAAGAACAGAACCCAAAGAACAGGAGAAACCTGATCTGCGCCGTCCGCGGGGTAAGAAGTTACAGCAAACGATCTCTGCTCAGGAAAGACTACTGAATGATCTGAAGCGCAGCTTATGCTCCCTACCGGAAATAGCAGAGGAGTCATGCACAGGAAAGAACGAATTGGACGTATCTACATTTCCAGCCGATACCGGGGCTGGTTGCGTACCTCCCGCTCAGGTGTCAGTCACAGTCTCCTTGCAAATAGAGGCCGCCGCTAATGTAGAAGATGATGAGAAAACTCCGGAGAAAGAGAATGCCATGTCAAGCGGATCTCAAGTTGATGGCAAGtcaaaaacaaatcgaaagaTTACGAGCTACTTCACCGACGTAGGCCAGCAGGCAGAAACGAAAACCTAA
Protein Sequence: MVNVPVPMPSVLKAAKKTNGDSIMVAASNAAAALGDNEDSDESELEEDDDLLDDPDDVILQIDSEDEAELEAQRIRLDVKAAAAAAAAETAETTTKSQVSNGNKQKQQNQQQTNNKAASRKPRGRPPGTGNKNKRNKSGGRNSRSSEASTASSLVAAEVLADEKWHRFFYKCSLCCNQYSDGLSLSRHFQKEHPVQDCQQAKRKRGRSKCSSIGIESHTPLDMSSLNLGYLKPCAQLLIEGESLLQLCLACNSQFVDVKHFRRHLSEQHGYFKLLVPKEEPTEVPPTLAAIAMSKSSQQFQLPIPAPDTPPPEQDGKDSSGNGSRNEKDDLDILNAMVAKMAAVRGKQNCVHKVNKMIIKLPGVAKHGKKVNDQAEYPKQTEKEQKRPDYMENPETKNEDKSEKAVQDPQQCPEEIEPAKRKRACKKLVPSSLDPEKNIKKEMESSERCMRKTRNFVDYVMDLKDEEDEDAEETEGSSATVSPRNSSSDESLFSIKRESIEESQSTGRRIHTCNFCGKAFQRFSRMQDHLRIHTGEKPFTCNHCGRAFRLKMRLAEHKLRHRTEKAYQCEICSMPLATKQDLSLHMRHHKNDRRYKCDKCDKGFVRSSDLAIHVRIHTGEKPYACDLCGKAFRARQNLVVHRRTHLGDKPIQCELCEKRFARKIDMRVHMRKHTGEKPFNCESCQRGYSSRVNLQRHQQREHGKGSQNAVRKTTGQGKDIKPEAGNDSIPQNETQSKTEQRTEPKEQEKPDLRRPRGKKLQQTISAQERLLNDLKRSLCSLPEIAEESCTGKNELDVSTFPADTGAGCVPPAQVSVTVSLQIEAAANVEDDEKTPEKENAMSSGSQVDGKSKTNRKITSYFTDVGQQAETKT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00536260;
90% Identity: iTF_00515097;
80% Identity: -