Basic Information

Insect: Drosophila subobscura
Gene Symbol: -
Assembly: GCA_008121235.1
Location: NC:23832267-23838670[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 0.003 0.18 11.9 0.8 1 23 193 215 193 215 0.98

2 7 0.0046 0.28 11.3 4.4 1 23 544 566 544 566 0.96

3 7 6.2e-05 0.0037 17.2 3.1 1 23 572 594 572 594 0.98

4 7 3.1e-06 0.00018 21.3 0.7 1 23 600 623 600 623 0.96

5 7 2.1e-06 0.00012 21.9 2.9 1 23 629 651 629 651 0.97

6 7 5.6e-06 0.00033 20.5 0.7 1 23 657 679 657 679 0.97

7 7 9.4e-06 0.00056 19.8 1.8 1 23 685 707 685 707 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	0.003	0.18	11.9	0.8	1	23	193	215	193	215	0.98
2	7	0.0046	0.28	11.3	4.4	1	23	544	566	544	566	0.96
3	7	6.2e-05	0.0037	17.2	3.1	1	23	572	594	572	594	0.98
4	7	3.1e-06	0.00018	21.3	0.7	1	23	600	623	600	623	0.96
5	7	2.1e-06	0.00012	21.9	2.9	1	23	629	651	629	651	0.97
6	7	5.6e-06	0.00033	20.5	0.7	1	23	657	679	657	679	0.97
7	7	9.4e-06	0.00056	19.8	1.8	1	23	685	707	685	707	0.97

Sequence Information

Coding Sequence: ATGGAGCGCAAAGAAGTGGATGCACAGCAGTACATTGATCACACGCTGCTGGCCTCGGAGCTAATGCGGGATCCAAATCACTTTATTATGGATCTAATCGATCACACGGGCGTGTTTCCCAAAGCCGAGGGACCCACCAACCTGACCACCAGCACAGGGAATGCCCCAAATGATGGGACTGGCGGCTACGTGGAGAAGGATGCCCTGACGCCGGAGCTGAATTTTCACAACACAATTTTCCAGTTTGTGAATAAACATGTGAACGAGTCCTCGTCGGGGGACAGTGTAGTGGGTCCGGTGGTGTCCCAGCAAGTGCCGCAGCCTGCCTTCCCAGCCCTCGCCATAGAGCCCACAGTGCCCATCGATGTCTCGACGGGTCTGCACGCTGTCGACGATGATGATCTGCTGTATGTGCACAATGCTCTGACGACCAATGCCCGCAAGGTGCTGCCACACAAGAAGCGCATCTCGAGGAAGCTCAAGGGCAACATCGAAGcggagatggagctgcagcatcaacagcagcagcagcacaaacatgTCGTTCAGCATGTGCCCGTCGGAGCGGCCGCGCTCTATAGCTGTGAGATCTGTGGCTATGCCGTGCACACACAATTGGATTTCTTTGCACATCTCAAGCAGCATTATGAGCCACCAATGGCCATGGAGCAGCGACTGGAAGTGCccatacagcagcagcagcaagagcagcagaaggagccaCTGGACATGTGCGGTCTGTCGTCACAGGATAAGCTGCAACAGGAGCAGGCCAAATTGGATCAAGTCTTTCACGATGTTCAGCTGAACTTTGAGAACTTTCATCCCATTAGTCATGTGGATCACgatgtgggcgtgggcgtgggcgtgggagTGCCTGTAAATGTCAACGATGTCGGTGTCAATATGGTCATGCATGGCGAGGCCACAGACAAACTGAATTCAGTGggtgctggcagcagcacgcCCAACGTCAACGTTGTGGTGCCCGTTGTGGATGATGTGGAGTTCAGTGACACGGAGGACATGCTCGAGGGCATACGCAACGTGGTGGACAAGGTGTCCATTGAGGACACTTGCGATGAGCTGGTGGATCTGGAGCTAAGCACTGCCACGATACGAGCGCCCTGGTTTAACAACAACTTCAGTGACATCACATTCccgggcctgctgctgcctggggAGCCGCCTCCAGTATCAGCGGAGCAAGGGCCGACGCCGCTGCTCAAAGAGGATCATCCCAATGAAGCGGAGCAGATGGATTTGGATTTCCTCAATGCCAGCAAACGAGAGCAGTCAAATGATGTCAAAATGGAGAAGCTGGAAAAACCCATCGAGGGGATTGAACAGCCTTTGCTGGTGGCGCCACCAATGTGTTGTACGTCTCCGGCTCCACCTCCTGCGCCGCCGCCTGGCTCGGCCATTGAACAGCTGCGACGTTCCCCGCTAGTTCTACACGAAGCCGCCTACAAACTGGAGGCTGATGAAATGCCCGACGACAGCGCACCGCCCTCACCATTTGAAAGTGAAGAAATCGACAGAGAGGATGAAGACGTTACCGATGGCTATGCCATGGAGAGCATAGACACAAGTCCCAGCGACGACTCCCCGAGCAAAGCGAGGAGGAAACACTTTTGTGAGAAATGCAACAGGGACTTCAATTCATACAATGCCCTCAAATATCATCAATATACACACAACCAGGAGCGGTCGCACAAGTGCAGAAGCTGCGAAAGATCCTTCTACAACCAAAGTGCGCTCACGGCACACGAGAAAACGCACTCTGGGGTGAAGCCCTTTGAGTGCGAGAAATGCGACTACAAGTTCCGACAGTGGGGCGATCTCAAGTACCACATCATCTCCAGACACAGCGACATCAAGGCCCACATGTGCGAGTTCTGCGGCAAGAGCTTCTCCCGAAGGTACTCCCTGGTGCTGCACCGACGGATCCACACCAGCGAACGGAACTACGCCTGCCAGTACTGCGACAAAACGTTTCGTGCAAGTTCTTACCTTCTCAGCCACGTCAAGGTGCACACGGGAGAGCGACCGCACGAATGCGACGTGTGCCAGAAGCGGTTTCGCGTCTCGGGGGATCTCAAGCGGCATTCCCGCATTCACGATCCGGCCAGAAACAGTCAGCCCCCCGCCACAAAAGTCAAGAAAAAGAAGCTGAAGCAAATCAAAGACCAGATCCCAAATGAGAatgaggtggaggaggaggtggtggcggtggccaaCCGTAAACATAAGTCTGACGCCCTGTGCGACGAATCAGAGCAGGAAATTCTCGGCTTATAG
Protein Sequence: MERKEVDAQQYIDHTLLASELMRDPNHFIMDLIDHTGVFPKAEGPTNLTTSTGNAPNDGTGGYVEKDALTPELNFHNTIFQFVNKHVNESSSGDSVVGPVVSQQVPQPAFPALAIEPTVPIDVSTGLHAVDDDDLLYVHNALTTNARKVLPHKKRISRKLKGNIEAEMELQHQQQQQHKHVVQHVPVGAAALYSCEICGYAVHTQLDFFAHLKQHYEPPMAMEQRLEVPIQQQQQEQQKEPLDMCGLSSQDKLQQEQAKLDQVFHDVQLNFENFHPISHVDHDVGVGVGVGVPVNVNDVGVNMVMHGEATDKLNSVGAGSSTPNVNVVVPVVDDVEFSDTEDMLEGIRNVVDKVSIEDTCDELVDLELSTATIRAPWFNNNFSDITFPGLLLPGEPPPVSAEQGPTPLLKEDHPNEAEQMDLDFLNASKREQSNDVKMEKLEKPIEGIEQPLLVAPPMCCTSPAPPPAPPPGSAIEQLRRSPLVLHEAAYKLEADEMPDDSAPPSPFESEEIDREDEDVTDGYAMESIDTSPSDDSPSKARRKHFCEKCNRDFNSYNALKYHQYTHNQERSHKCRSCERSFYNQSALTAHEKTHSGVKPFECEKCDYKFRQWGDLKYHIISRHSDIKAHMCEFCGKSFSRRYSLVLHRRIHTSERNYACQYCDKTFRASSYLLSHVKVHTGERPHECDVCQKRFRVSGDLKRHSRIHDPARNSQPPATKVKKKKLKQIKDQIPNENEVEEEVVAVANRKHKSDALCDESEQEILGL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00517930;
90% Identity: iTF_00515086;
80% Identity: -