Dsub002042.1
Basic Information
- Insect
- Drosophila subobscura
- Gene Symbol
- -
- Assembly
- GCA_008121235.1
- Location
- NC:21062338-21068419[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 12 0.011 0.63 10.2 3.7 3 23 270 290 268 290 0.97 2 12 0.0029 0.17 12.0 0.6 1 23 296 321 296 321 0.92 3 12 0.022 1.3 9.2 1.9 1 23 328 353 328 353 0.95 4 12 5.9e-05 0.0035 17.3 1.3 1 23 365 387 365 387 0.98 5 12 1.7e-06 9.8e-05 22.2 0.1 1 23 394 416 394 416 0.98 6 12 0.01 0.62 10.2 0.2 1 23 422 444 422 444 0.97 7 12 0.017 1 9.5 3.0 1 23 450 473 450 473 0.98 8 12 0.0088 0.52 10.4 4.4 1 23 479 501 479 501 0.96 9 12 0.088 5.2 7.3 5.3 2 23 508 529 507 529 0.96 10 12 1.4e-05 0.00084 19.2 1.9 1 23 639 662 639 662 0.96 11 12 0.038 2.2 8.5 7.1 1 23 668 690 668 690 0.94 12 12 3.1e-06 0.00018 21.3 2.3 1 23 696 718 696 718 0.99
Sequence Information
- Coding Sequence
- ATGGACATGGGCAGGACATATTCGATACACACGCTGTGTCGCGTTTGCCTGAACCACTTGCAAAACGATGCCGCATACGATTTGTATCTGGTGCCAGGCCTGTCGAAAAAACTGTGTCTGTGTACGTCCCTCTCCGTCGAGCAGAACGATGGCTTTCCCAAGAACCTGTGCAGCAATTGCTACACCAGGCTGAACGACCTGCACGATTTCCAAAAACTGTGCGTCGACTCGGTCCAGAAGTTCCAGGATCTGGTCGCCAGCAACGTTTTCACCTGCCAGACGAACTTCGATGTGCTGGATCCCAGTTCGACGGCCCACGATCTGCCAGGAGAGGACGAGGACCACATCAACTTTGATCCCCTATTGAACCACAAAATGGAGCTGATTGAGAACGAGGAGGACGTGTTCAAGATGCTGGAGCATGTGGACAAGGAGGCCGAGGAGTGTGAGAACGAGAGCGTCAAGCAGGACAAGGTGAAGGCTTCGCCCAGCAACGCTCTGCGAATGTTCGACGATGACTCCTCCCTGGAGAGCGGCAATGACAACGACAGAGATGTGGACTTTGagcccaacagcagcgacgacgacatTCCTTTGGCCCAACGCATGAGGGGAAccacccagtcccagtccaccCGCACACCAGCCAaggccaagcccaagcccaagaagAAGCCCAAAGTGGTGGACTACGATGACTtcagcagcaccacctccGACTcggacgacgacgatgactcGAACAGGGAGAAGCCCAAACGCAAGAGGATCCCAGCCGATGAGCGGCACCTTCATCGCATCATTGACTGCCACATTTGTCATCAGAAGTTCAAGAAGGCCATCCGCTACGAGGAGCACATGAAGTACCACAACGATCTGCTGCCCTTCCAGTGCAAAGTGGAGACCTGCCGCAAGGGATTCACCACAGCCAATGGCCTGCGCATCCATGTGGACCATGCCCACACCGAACTGTCCGAGGTGCACCATTGTCCAGCGGAGGGTTGCGAGAAGACGTTCCCACGCATCAGGCTGCTCACGTTCCACATGAAGAAGGTGCACAACATAACGAAGTCGGCCGCTCCGCTGCGCGACTTCCCCTGCCCGGAGTGCGACACCGTCTTCCGCTGCCCCACGGCCCTCAAGAAGCACATGTACAAGCACACGGGCGAGGAGCTGCCCTACCCATGCAACATCTGCGGCAAGCGGTTCGTGATCAACAGCGCCCTCAGGGACCATCTGATGCGGCATGCGGGCATCAAGAATCACGTCTGCCCCTACTGTGGCGTGGGCAAGACGACGCGCCAGGAGTGGAACGCTCACATTCTCACCCACACCAAGGAGAAGAAGTTCAAGTGCCGGCAGTGCGATCACGCCTCGCACAACAAGCAGGCCCTGTCGAACCACATCAAGGTGGTGCACGAGAAGCGGAAGGACTTCGCCTGCCAGTACTGCGGCAAGACGTTCGGCAAGTCGCACGCCTGCAAGGTGCACGAGCGCAGTCACACGGGAGAGAAGTGCTGCGAGTGCAAGATCTGCGGCAAGATTTTCCTCTGCGAGAAGAGCCTGACGAAGCATCTGAAGACGCACGAGAAGCGGGATCTGCCGCCGTCAGAGccgcaacggcaacaacagcttaacattcccattccgatACCGGGCCAGATGCAAGGCGATGGCCTGGggaatcccaatcccaatgcaAACAGCAATATTAATCCCAATCAAAACGAGGACATGCTCAAGGCTTGCGCTAGCAGTGGCGGGCCCGCTGCACCGCTGCCCAAGCAGAAGAACTCCAGGCGCGTCCAACGGGTGGACATTTCCCAGCTGGCGGGCACGGCCGTCAATCCCATACCGTCGGTGTCGGTACCGTCATGGTCGCCGCAGGTGAACTTCACCAAGAAGGAGGGCCAGCACATGTGCCCGGACTGCGGCAAGGGATTCAATCATGTGAGCAACATGAAGCTCCATTACAAGGTGGTGCACCAGAAGGTGAAGGacttctgctgccgcttctgcccCAAGCGGTTCGCCAAGAAGCAGTATCTGCGCCATCACGAGTACATACACACCGGGGAGAAGCCGTACGAGTGCAAGGTGTGCGGCAAACACTTCCGCCAGGAGCAGGTGCTCAAGACCCATATGAAGGTGCACGCCAAGCCGCCGAGGCCGCCACTCAAGCCCAAGGAGCCGGTCGCACCCAAGCCGGAGACGGTGAAGCGACCGCATCCAAAGAATTATGAGCAGTACCAGGATCCGGCTGCGGAGCgggctgccgccaccgccgagCTGTTGGCCTTCCAGCTGGAGGAGAACGAGGCTAAGCGGAaggcggaggtggagctgCGCAAAATCCAGGAGGCGGCATTCGAGCAGTTGAacaagctgcagaagcagtCGAACACCTACGATGGATTCTATGCCCAGAAGGCCGAGGCGGAGGGCGCCACCGTCGATACATTCAAGTTGGATCATGTCTGA
- Protein Sequence
- MDMGRTYSIHTLCRVCLNHLQNDAAYDLYLVPGLSKKLCLCTSLSVEQNDGFPKNLCSNCYTRLNDLHDFQKLCVDSVQKFQDLVASNVFTCQTNFDVLDPSSTAHDLPGEDEDHINFDPLLNHKMELIENEEDVFKMLEHVDKEAEECENESVKQDKVKASPSNALRMFDDDSSLESGNDNDRDVDFEPNSSDDDIPLAQRMRGTTQSQSTRTPAKAKPKPKKKPKVVDYDDFSSTTSDSDDDDDSNREKPKRKRIPADERHLHRIIDCHICHQKFKKAIRYEEHMKYHNDLLPFQCKVETCRKGFTTANGLRIHVDHAHTELSEVHHCPAEGCEKTFPRIRLLTFHMKKVHNITKSAAPLRDFPCPECDTVFRCPTALKKHMYKHTGEELPYPCNICGKRFVINSALRDHLMRHAGIKNHVCPYCGVGKTTRQEWNAHILTHTKEKKFKCRQCDHASHNKQALSNHIKVVHEKRKDFACQYCGKTFGKSHACKVHERSHTGEKCCECKICGKIFLCEKSLTKHLKTHEKRDLPPSEPQRQQQLNIPIPIPGQMQGDGLGNPNPNANSNINPNQNEDMLKACASSGGPAAPLPKQKNSRRVQRVDISQLAGTAVNPIPSVSVPSWSPQVNFTKKEGQHMCPDCGKGFNHVSNMKLHYKVVHQKVKDFCCRFCPKRFAKKQYLRHHEYIHTGEKPYECKVCGKHFRQEQVLKTHMKVHAKPPRPPLKPKEPVAPKPETVKRPHPKNYEQYQDPAAERAAATAELLAFQLEENEAKRKAEVELRKIQEAAFEQLNKLQKQSNTYDGFYAQKAEAEGATVDTFKLDHV
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00484614;
- 90% Identity
- -
- 80% Identity
- -