Basic Information

Insect: Drosophila subobscura
Gene Symbol: -
Assembly: GCA_008121235.1
Location: NC:7687565-7690979[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 0.00025 0.015 15.3 3.6 1 23 174 197 174 197 0.97

2 15 0.00052 0.031 14.3 1.2 1 23 243 266 243 266 0.96

3 15 0.0027 0.16 12.1 5.9 1 23 333 356 333 356 0.96

4 15 0.0012 0.071 13.2 0.7 2 23 418 439 417 439 0.97

5 15 0.017 1 9.5 0.6 1 23 582 604 582 604 0.94

6 15 0.00044 0.026 14.5 2.4 1 23 611 634 611 634 0.96

7 15 0.00075 0.044 13.8 0.4 2 23 643 664 642 664 0.95

8 15 0.0091 0.54 10.4 0.1 2 20 691 709 690 714 0.90

9 15 0.0014 0.086 12.9 1.6 1 23 749 772 749 772 0.96

10 15 2.8 1.7e+02 2.6 0.7 3 22 781 800 779 800 0.95

11 15 1.6 94 3.4 1.9 1 23 809 832 809 832 0.94

12 15 1.5e-05 0.00087 19.2 0.1 1 23 854 877 854 877 0.97

13 15 0.085 5.1 7.3 0.1 1 23 887 909 887 909 0.92

14 15 5.5e-05 0.0033 17.4 3.7 1 23 915 937 915 937 0.99

15 15 5.7e-06 0.00034 20.5 3.2 1 23 943 965 943 965 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	0.00025	0.015	15.3	3.6	1	23	174	197	174	197	0.97
2	15	0.00052	0.031	14.3	1.2	1	23	243	266	243	266	0.96
3	15	0.0027	0.16	12.1	5.9	1	23	333	356	333	356	0.96
4	15	0.0012	0.071	13.2	0.7	2	23	418	439	417	439	0.97
5	15	0.017	1	9.5	0.6	1	23	582	604	582	604	0.94
6	15	0.00044	0.026	14.5	2.4	1	23	611	634	611	634	0.96
7	15	0.00075	0.044	13.8	0.4	2	23	643	664	642	664	0.95
8	15	0.0091	0.54	10.4	0.1	2	20	691	709	690	714	0.90
9	15	0.0014	0.086	12.9	1.6	1	23	749	772	749	772	0.96
10	15	2.8	1.7e+02	2.6	0.7	3	22	781	800	779	800	0.95
11	15	1.6	94	3.4	1.9	1	23	809	832	809	832	0.94
12	15	1.5e-05	0.00087	19.2	0.1	1	23	854	877	854	877	0.97
13	15	0.085	5.1	7.3	0.1	1	23	887	909	887	909	0.92
14	15	5.5e-05	0.0033	17.4	3.7	1	23	915	937	915	937	0.99
15	15	5.7e-06	0.00034	20.5	3.2	1	23	943	965	943	965	0.98

Sequence Information

Coding Sequence: ATGACCCGGACCTGCAGAATCTGTGGAGATACAAATGGGCGTTACAGGATCGAGACGACGGTGGAGAAGTATGCCGAGAAGTCCTTCAATCAGCTGTTGCTGGAGCTAACCAAAATTGAGTTGACCATGGTCCAGGCCGAGAAGTTGCCCCACTGGCTGTGCTCCAGTTGCTCCCAGAAGCTAGAGAGTGCCTATGAATTTGTACTGCTAGCGAAGCAGACGCACAAGCAGTGGCTGCAAAAACTTCAGGATACGGGGGAGATAATGGGCACTGGGTCCTTGGAGTGCCTGCGGGAGACCCCCATACACCTATTTGAGATCGAGGGGGTTACCATCAAAACGGAAGCGCTAGAGTCAACGGCTGCAGATAACGGGAAAACCTCCTGCGATCCTCTAGTCCGCACACGCATTAAAAAGCGTACAATCTTTCACTTCAGCGACACGGAGGATGACCAGGATGATGTGCCGCTAAGGCAACGCAGGGCGAGAAGTCAAGCGAAACGCTCATCAGCAAAGCAGCACAAATGCAATCTGTGCGGCAAATCCTACATTTATATCACAAATCTATATCGCCACAAGAAAAGGGATCACGGCTATCCAGGACATTCGAAGAGTGAGAGCTCCGAGTCCGCCCatgacaacaaacaaaagagcgCCGTGGCACCGCAAGACAGTTCCAACTTGGAaaaaaacgAAGATGAcaatgatgaggatgatgacaACTACTACAAGTGCGATCAGTGCGATAAATCCTACAAGTACATAATGATGCTAGTCAAGCACAAACAGAATGCCCATGAAGCTAACCAATATCAACTGCCAATCAAATCTGTGACCAAGcgaaaaaacagaagagacGTGGGCGAAGCGGCAAGCCCAGCTTCTTCTGGGAAATCCACACAACGCAGCAGAATCAGCAACGATAGCCTAGTCCACAGCCTCATCAAATCAGTGGAGCTTTCCGATGAGGATGCAAACAGCGGCAACGATAACTACTACAAGTGTGATCAGTGCCACAAGTCGTACAAATACATTATTAACCTCatcaagcacaagcacaaggaACACACGGAAGCCGACAACAACTCAGACGCCGAGGATAATCCACAATTGGCCTCCACATCTGCCTGCGCCGCTCCATATGCTAGCGCCTCCGCAGCTGCAGGCTCTTCCGCCAAAGCATCGCGAATCAATCGTCGCGTTCAGGGCTTCGACCCGCATCGCTGCGAGCCGAATGGCGCGAAGGAAATTCAGTGCATGATCTGCCTGCGAAAGTTCACTAAATTGCGAGAGCTGAGAGAACACCTGAGGGCGCATCCCACGGACTTTAATTTTCAGGAGCACGGTGAGCCCATTGAACGCATTGCCGAGGGCTTCTTCAAGACGGCTGTTGAGTCCACTGTGGAGGGTCTGAAGGACAGAATTCTGCGTAATCTCAAGATGGGTGTCTTCGGACGCTTCTATTCCATTACCAACGAGGCGCGCTACGAGATGAATTTGGACAGCTCGGACACGGATAGCGATGGCGATGCAGATGTTGTACTACGACGAAGCTATGCCTGTGAGCTATGCGACGCACCAGAGGCCCGGTGGCCGCGCAAGTATCAGCTGCACGAGCatcacaggcagcagcacacttGGGAAGAAGCTCCGCATGTGTGCCAGCGCTGCGACGCGCGTTTCCTCAgtctccagctgctggagcatcaTACCCTTCAGCTGTGCCATAACACACTGAAGCGATTCATGTGCGACAAGTGCCCGCAGCGCTTCTTCTGGCGTAGAAATCTGCGTGCCCATCTGGTCGAGCACAAGAGCAAGCAAGACAACTATCCGTGCGACCAGTGCCAGCGTAGTTTTCAGCATAAAAGCGCCGTGACCAAGCACAAGTTGATGATGCATCGCGATGAAAAGAATCAGCTTATTCCCTGCCGCTGGTGCTCACGGACATTCTACCGTTCCGGCCTCCTGTACAAGCATGTCGAGCGCCATGGCTTCACCGGCGACGACATGCCACTGGCAGAGACTTTGCTGGCCGATGCAGCCAAGCCATCGGGTCCAAAGACTGTCCAGTGCAAGCTCTGTGATCTGCAGTTCGTAAGCGTAGCAGATCTACGTCGGCACAATGCAATGCTGGGCCACAGTGACCGGATAACCGACTACATGATCAGCACTGAGACCGgcttcgagctgctgctggaggataCAGATGACAGCGATGACGACACTACGGGTGGCAGGTCCTACTCCTGCGATCTCTGTCAGATGACGTTCCGTCGCCGAAGAGAGATGAGCGAGCATCAGTATTCCCTGCACACATTTGACAAGCTGCCGTATGGCTGCGAACATTGCATTTACAAGACCGTGGATAAGCTCATGCTGGAGCATCATCTGCGCACACAATGCCTGAACACCACGAAGCCGTTcagctgctcccgctgcaGATACAAGTTCATGTGGAAGGAGAACCTGGATCAGCATTTTGCCACGCAGCATTCCAAGCAGCCACCCGCCCAGGAGCAGTCGTCTATGCCCTTGAGGAGAAGGCGACGCTTCAGGTATCAATGCCCTCAGTGCTGGCGTTCGTTTGTGGTGCAGGCCAGCCTTGATAAGCATATAAGGGACATGCATGTGGCCAAGAAGAATCCGCGCAAGAAATATCTGTGCTCCCTGTGTGGCCTGGAGGCGCTGACGCCCAACAAGCTCAACATTCATATGCGTCGCCACAACGGGGAAAAGCCCTTCAAATGCGATCTCTGCGACATGCGCTTCACAGTCCACTACGAGCTAAAGGTACATCGGAGGAAGCACACCGGCGAGCGACCCTACCAGTGCACCTTTTGTGACAAGCATTTTGCCCGACCCGACAAGCTGAGACGCCATGTCTACATGCACAGTGCTCGTCGCTAG
Protein Sequence: MTRTCRICGDTNGRYRIETTVEKYAEKSFNQLLLELTKIELTMVQAEKLPHWLCSSCSQKLESAYEFVLLAKQTHKQWLQKLQDTGEIMGTGSLECLRETPIHLFEIEGVTIKTEALESTAADNGKTSCDPLVRTRIKKRTIFHFSDTEDDQDDVPLRQRRARSQAKRSSAKQHKCNLCGKSYIYITNLYRHKKRDHGYPGHSKSESSESAHDNKQKSAVAPQDSSNLEKNEDDNDEDDDNYYKCDQCDKSYKYIMMLVKHKQNAHEANQYQLPIKSVTKRKNRRDVGEAASPASSGKSTQRSRISNDSLVHSLIKSVELSDEDANSGNDNYYKCDQCHKSYKYIINLIKHKHKEHTEADNNSDAEDNPQLASTSACAAPYASASAAAGSSAKASRINRRVQGFDPHRCEPNGAKEIQCMICLRKFTKLRELREHLRAHPTDFNFQEHGEPIERIAEGFFKTAVESTVEGLKDRILRNLKMGVFGRFYSITNEARYEMNLDSSDTDSDGDADVVLRRSYACELCDAPEARWPRKYQLHEHHRQQHTWEEAPHVCQRCDARFLSLQLLEHHTLQLCHNTLKRFMCDKCPQRFFWRRNLRAHLVEHKSKQDNYPCDQCQRSFQHKSAVTKHKLMMHRDEKNQLIPCRWCSRTFYRSGLLYKHVERHGFTGDDMPLAETLLADAAKPSGPKTVQCKLCDLQFVSVADLRRHNAMLGHSDRITDYMISTETGFELLLEDTDDSDDDTTGGRSYSCDLCQMTFRRRREMSEHQYSLHTFDKLPYGCEHCIYKTVDKLMLEHHLRTQCLNTTKPFSCSRCRYKFMWKENLDQHFATQHSKQPPAQEQSSMPLRRRRRFRYQCPQCWRSFVVQASLDKHIRDMHVAKKNPRKKYLCSLCGLEALTPNKLNIHMRRHNGEKPFKCDLCDMRFTVHYELKVHRRKHTGERPYQCTFCDKHFARPDKLRRHVYMHSARR

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00575022;
90% Identity: iTF_00515107;
80% Identity: -