Basic Information

Insect: Drosophila subobscura
Gene Symbol: -
Assembly: GCA_008121235.1
Location: NC:12624008-12626971[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 1.4 84 3.5 5.1 1 23 285 307 285 307 0.98

2 11 8.4e-06 0.0005 20.0 0.1 1 23 313 335 313 335 0.98

3 11 0.0015 0.091 12.8 4.1 1 23 341 364 341 364 0.97

4 11 0.31 18 5.6 3.8 1 20 370 389 370 392 0.95

5 11 0.0072 0.43 10.7 1.7 1 23 398 420 398 420 0.97

6 11 3.5e-05 0.0021 18.0 1.2 1 23 426 448 426 448 0.98

7 11 0.0023 0.13 12.3 2.8 1 23 456 479 456 479 0.95

8 11 0.00085 0.05 13.6 0.4 2 23 486 507 485 507 0.97

9 11 0.001 0.06 13.4 1.4 1 23 513 535 513 535 0.98

10 11 2.5e-06 0.00015 21.6 0.7 1 23 541 564 541 564 0.96

11 11 3.9e-07 2.3e-05 24.1 3.8 1 23 578 600 578 600 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	1.4	84	3.5	5.1	1	23	285	307	285	307	0.98
2	11	8.4e-06	0.0005	20.0	0.1	1	23	313	335	313	335	0.98
3	11	0.0015	0.091	12.8	4.1	1	23	341	364	341	364	0.97
4	11	0.31	18	5.6	3.8	1	20	370	389	370	392	0.95
5	11	0.0072	0.43	10.7	1.7	1	23	398	420	398	420	0.97
6	11	3.5e-05	0.0021	18.0	1.2	1	23	426	448	426	448	0.98
7	11	0.0023	0.13	12.3	2.8	1	23	456	479	456	479	0.95
8	11	0.00085	0.05	13.6	0.4	2	23	486	507	485	507	0.97
9	11	0.001	0.06	13.4	1.4	1	23	513	535	513	535	0.98
10	11	2.5e-06	0.00015	21.6	0.7	1	23	541	564	541	564	0.96
11	11	3.9e-07	2.3e-05	24.1	3.8	1	23	578	600	578	600	0.97

Sequence Information

Coding Sequence: ATGGCGAAATCGTCGCCTAAATCATCCGAGGATCTGCAGTCGTTTCTGAAAAATTTCCACAAGGAAATAGAAGACGGCAGCGACGACAAAGTTGTGCACAAGATTCTAAAATCAATCAGAGACGAGGACGGCGTCACCGACGACCATGAGGGATATGCTGTTGCCTCTGAGGAAGATCAGTCGGAGCAAGATGAGGACTACGATCCAGGTGAAGAGGAAGATGATGGCGACAAATACTTCATTGACGACGACGGAAACTGCTATATCAAGACTAcccaaaagcagaaagaactGCTGGAAAAGCTGAAGAACTcagcaaaaaacacagcaaGACCATCCCTGCAAAGGCTGGCAAGCCGTCCAACAAAGGTGATCATCAATTTACGGCCTGCCCAGTCTTCCACGAAAAGGGTCACAAGATCTgcagcagagccaaagccaatcaGTGTACGAGCagcgagtgcagcagcagtcgtagCTGCTGctagtcccagtcccaagCTGCCAGAAAAGACATTTGCTAAAAGTACCAGAGGCAGGCCCAAAAAGGCAATAAAGCTTCCCTCTCCGAAGCGCGAGCCAAAGACCGAAGCCCTTGACATAGAGCGCGAGATGGAGGAACTGGTGGCTGACACAGATGAGGCAGCTGTCGTAGCCGATATCGCTGATAATTCGGAATACACCCTTGACAATGCTGCCGTAGAAGCACTGGACAATGTGGCTCACGGCGAGGTCTATGAGTTCGATGACAACCCACCGGAGGACTCcaagcaggagctgaagaTCACCAACAGGCAGTTCTTGCTGAAACCAGTGCCAACTGTGGAGAAGAAAACGTCCAAGACGCATCACTTCAGCTGCTCTCATTGCGCCTACACGACCAACAAGAAGTTTCTCATCTCGCgtcacaacaaaacacacgcGACTGAGTTCTCCTACATATGCTCGATATGCGATCGTGGATTCAAGACCAATGTGGGATTGGTCAACCATGTGAACACCCATTTGGGTAATAAGCCGCACAAGTGCAAGCACTGCGAGAGCGCCTTTGTGACCACTGGCGAGCTGATAAGACACACCAGATACAAGCACACCAAGGAGAAGCCCCACAAGTGCACAGAGTGCAGCTACGCTTCGGTGGAGCTGACCAAGCTGAGACGCCACATGACCTGTCACACAGGAGAGCGGCCATACCAGTGTCCCCACTGCACCTATGCCTCGCAGGACATGTTCAAGCTGAAGCGTCATCTGGTTGTCCACACGGGCGAGAAGAAGTATCAGTGCGATATTTGCAAGTCGCGGTTCACGCAGTCCAACTCCCTAAAGGCGCATAAACTGATCCACAGCGTTGTGGACAAGCCCGTGTTCCAGTGCAGTCAGTGTCCCACTACCTGTGGCCGGAAGGCGGATCTGCGCCTTCATGTCATGCACATGCATACGGCAGACAAACCGATACCCTGCAAGCGCTGTGGGCAAAATCTGCCCGATCGCTACCAGTACAAGCTGCACATAAAGACCCACGAGGGCGAGAGATGCTATCGTTGCAAGCTGTGCGAGTACGCCTCTGTTTCCAAGCGCCATTTGGACTCGCACATGCTCATCCACTTGGGTGAGAAGCCCTTCGTGTGCGAGATGTGCCCGCAGAGGTTCCGTCAGCGCCAGCTGCTGCGTCGCCACATGAATCTTGTGCACAACGAGCAATACCAGCGACCCGAGCCGCGCGAAAAGGTGCACAGCTGCCCGAATTGTCCGCGCACATTTACCCACAAGGGTAATCTCATGCGGCACATGGAGCGTCATGACGACTCAAAGAATACTCGCGAGGAGCGgctgaaattaaaaatgggTCGCAATGTTCGTCTACAGCCCGATGGCAGTATCGTGACTCTGGTCAACGAACGTGACTTTGAGAAAGGATTCATTGACATGgatgaagaagaagaagagaacTTTGAGCTGGCCGACGTGGAGCCGGACAACTATGATGATGAAATATTGGATGCCATGGAGATCAAACCTGTCGGGAAAGCTAAGAAAAGTCCGGTCATCATTAACACACAACCCAGAAAGAGCTCCATCAATCAGCCCGTCATTATTAACCGCCGCCTCAGGAACCAAGGCGGCACCAAGACATTCCACATTAAGGAAGAGCCAAATACCTCAGAGTTCACGGTTGAGCTGGATGGCGATGATGGTCAGGTCATGGTCGTCGAACTGGTTAATGGTGAAGAGGAGGTGGTGGTCAAACGCGAGCCCAAAGCCTCCAAGATCAATGCCGCcaattgctttggctttgagGATGATGACGCTGAATTTGTGAATTATGGGGAACAAGAAACCGAAATGGATGGAACTTCACAGGAGTTTTTACAGCTAATGGACATGATTGAGCAAGATACTTAG
Protein Sequence: MAKSSPKSSEDLQSFLKNFHKEIEDGSDDKVVHKILKSIRDEDGVTDDHEGYAVASEEDQSEQDEDYDPGEEEDDGDKYFIDDDGNCYIKTTQKQKELLEKLKNSAKNTARPSLQRLASRPTKVIINLRPAQSSTKRVTRSAAEPKPISVRAASAAAVVAAASPSPKLPEKTFAKSTRGRPKKAIKLPSPKREPKTEALDIEREMEELVADTDEAAVVADIADNSEYTLDNAAVEALDNVAHGEVYEFDDNPPEDSKQELKITNRQFLLKPVPTVEKKTSKTHHFSCSHCAYTTNKKFLISRHNKTHATEFSYICSICDRGFKTNVGLVNHVNTHLGNKPHKCKHCESAFVTTGELIRHTRYKHTKEKPHKCTECSYASVELTKLRRHMTCHTGERPYQCPHCTYASQDMFKLKRHLVVHTGEKKYQCDICKSRFTQSNSLKAHKLIHSVVDKPVFQCSQCPTTCGRKADLRLHVMHMHTADKPIPCKRCGQNLPDRYQYKLHIKTHEGERCYRCKLCEYASVSKRHLDSHMLIHLGEKPFVCEMCPQRFRQRQLLRRHMNLVHNEQYQRPEPREKVHSCPNCPRTFTHKGNLMRHMERHDDSKNTREERLKLKMGRNVRLQPDGSIVTLVNERDFEKGFIDMDEEEEENFELADVEPDNYDDEILDAMEIKPVGKAKKSPVIINTQPRKSSINQPVIINRRLRNQGGTKTFHIKEEPNTSEFTVELDGDDGQVMVVELVNGEEEVVVKREPKASKINAANCFGFEDDDAEFVNYGEQETEMDGTSQEFLQLMDMIEQDT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00487449;
90% Identity: iTF_00515062;
80% Identity: -