Dsub012370.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila subobscura
Gene Symbol
Paris
Assembly
GCA_008121235.1
Location
NC:16053772-16056501[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 22 0.00019 0.011 15.7 1.3 1 23 147 169 147 169 0.98
2 22 5.8e-05 0.0035 17.3 1.4 1 23 175 197 175 197 0.98
3 22 0.00029 0.017 15.1 0.6 1 20 203 222 203 225 0.94
4 22 2.4e-06 0.00014 21.7 0.9 1 23 231 253 231 253 0.98
5 22 4.8e-05 0.0028 17.6 1.4 1 23 259 281 259 281 0.99
6 22 0.00083 0.05 13.7 0.9 1 23 287 309 287 309 0.97
7 22 0.00014 0.0084 16.1 3.3 1 23 315 337 315 337 0.99
8 22 1.1e-05 0.00065 19.6 2.2 1 23 343 365 343 365 0.99
9 22 1.1e-06 6.5e-05 22.7 4.8 1 23 371 393 371 393 0.99
10 22 0.017 1 9.5 0.2 1 21 399 419 399 420 0.92
11 22 3.7 2.2e+02 2.2 0.2 5 20 423 438 422 440 0.90
12 22 4.4e-05 0.0026 17.7 8.9 1 23 454 476 454 476 0.98
13 22 4.6 2.7e+02 1.9 0.1 5 20 486 501 479 503 0.90
14 22 2.1e-06 0.00013 21.8 7.2 1 23 530 552 530 552 0.99
15 22 4.6 2.7e+02 1.9 0.1 5 20 562 577 555 579 0.90
16 22 1.3e-05 0.00075 19.4 7.7 1 23 606 628 606 628 0.99
17 22 4.6 2.7e+02 1.9 0.0 5 20 638 653 631 655 0.90
18 22 1.5e-06 8.8e-05 22.3 5.7 1 23 682 704 682 704 0.98
19 22 0.0019 0.11 12.5 9.4 1 23 707 729 707 729 0.98
20 22 1.8e-06 0.00011 22.1 0.3 1 23 735 757 735 757 0.99
21 22 4.8e-05 0.0028 17.6 2.6 1 23 775 797 775 797 0.97
22 22 0.013 0.75 9.9 2.0 1 23 803 826 803 826 0.96

Sequence Information

Coding Sequence
ATGGAGGAAATATGCAGAGTTTGCTTGGGAACTTCTGGAGCattcacaaacatttttgatgaGACTCCAATAAGGAAAACTGGCATTGCTGAAATGATTACGGAGTGCACAGGATACGTGGTTTGGCGAGGGGATGCACTCCCAGAAAACATATGTCCACCCTGCCTAGAGGATGCAGTGGGCGCATTCTACCTCAAGAGAACCTGCGAGCAGAGCCATAAACTATATTTCACGCGGCTGGAGGaggaaagagaagaagaagaaatctGTGATAATGCAAAAGACGATAGTTGCGAGACGTCGGGTATTGGAAGTGAGCAATTAAACCAGTTAGAAACCGATGCAAAGGATCAAAGTGAGAAGGATACACTTAGTAGGCACTTAATTGATCATCCATACTCAAAGTCATTTAATCGGAAAGTGAGCCTTAAACCACCACATAAATGCCCTCGCTGCTTAAAGGCATTTTCTGAAAAAGAAGAACTAGACGTACACCGCCGTTCTCACGTTGGGGAGCGACCGTTCAAGTGTACTCACTGCCCGAAAGCATATATAAGTGAGAAAGTTCTTACAAATCACATACAAAGTCACACAGGATATCGACCATACAAATGTTCTTACTGCCCGAGATCATTTCAAGAGAAAGCGTTTCTCGAGAGACACCTACCCATTCACACGAAGGAGCGTCCACATAAGTGTCCTGAATGTCCAAAGTCCTATTTTATACCCAATAATCTAAAGATTCACATTCGTACGCACACGGGAGAACGACCATTCAAATGTTCCCTCTGTCCAAAAACCTATACATCAAGAGGTGTTCTCAAACTTCACAGCCGTACTCACACTGGGGAGAGGCCGTTTAAGTGTTCTGAATGCCCCAAGTCATTCGTTGAAAGCGCAGGTCACCGAACTCACATGATAATGCATTCCGATGAGCGACCCTTTCAATGCTCCCGCTGCTCAAAGTCATTTAAAATCAGACGCACCCTTGCATCACACACCCGAACTCACACGGGTGTACGAAAATTTCAATGCTCTCAATGCTCAAAGGCATTTGTAGAAAAACATGCACTAACGAAGCACCTCCTTACTCACACTGGGGAGCGACCATACAAGTGTGATCACTGCCCGAGATCATTTAAGCAAAATATATCTCTAAAAAAGCACTTAAAAAAACATCCAGATTATCGACCACATATATGTTCTTACTGCTCGGAGCCATTTCAAGAGAAAGCGGATCTCGACAGACACCTCACCACTCAGGCTGACTGCTCAAAGAAATTTGAACATGAAATAACTGTTAAAAATCACACCTCCAGTCAGTCGCAAAAGACTAAAGATCCTATCCTTAAGCAATCTTACCATTGTGATCACTGCACGAGATCATTTAAGCAAAAGACATCTCTAACAAAGCACTTAAAAAAACATCCAGATTGTCGACCACATATAAGTTCTCACTGCTCGGAGTCATTTCAAGAGAAAGCGGATCTCGATGAGCACCTCACTGACTGCTCGAAGTCATTTGAACTTGAAATATCTGTTGAACCGCAAGAGCATCAAATCTTTAATCACACTGGGGAGCGACCGTACAAGTGTGATCACTGCCCGAGATCATTTAAGCACAAGACATCTCTTACAAACCACATAAAAAAACATCCAGATTGTCGACCACATATAAGTTCTCACTGCTCGGAGTCATTTCAAGAGAAAGCGGATCTCGATGAGCACCTCACTGACTGCTCGAAGTCATTTGAACTTGAAATATCTGTTGAACCGCAAGAGCATCAAATCCTTAATCACACTGGGGAGCGACCGTACAAGTGTGATCACTGCCCGAGATCATTTAAGCACAAGACATCTCTtacaaaccacacacaaaaacatccAGATTGTCGACCATATGTTAGTTCTCACTGCTCGGAGTCATTTCAAGAGAAAGCGGATCTCGATGAGCACCTCACTGACTGCTCGAAGTCATTTGAACTTGAAATATCTGATGAACCGCAAGAGCATCAAATCCTTAATCACACTGGGGAGCGACCGTTCAAGTGTGATCACTGCCCGAAATCATTTAAGCACAAGCCATCTCTTAcaaaacacatacaaaatcaTCCAGATTATAAGTGTGAGCTCTGCTTTAAGTGCTTTTTTAAAAAGTCCCACCTTCGGGAACACACTTATACGCACATAGATGATGAACCATTTCAATGTCCTCAGTGCGCGAAAACATTTAAAGAGCAAGAGGCCCTCGAGACGCACATTCAAACACATGCGGAGGAGCGAATATATACGATTTCTGACTGCTATCCCAAGGTCAGTGTGTTTAGGTGTCCTCACTGCTCGAAGACATTTCCTGAATACGCAAATCTCCGCTATCACCTTTATTCGCACGCGAATGCACGACCCTACCACTGCTTCTTATGCAGAGCGACGTATACGCAATTACGCAGCCTCAAAGAACACTTATTAAGTGCTCACAATATCGAAGACAAGCGATCATATAGGCGGCCATCTGGTTATACAACTAAATTTAGAGAACATTATCATTTATAA
Protein Sequence
MEEICRVCLGTSGAFTNIFDETPIRKTGIAEMITECTGYVVWRGDALPENICPPCLEDAVGAFYLKRTCEQSHKLYFTRLEEEREEEEICDNAKDDSCETSGIGSEQLNQLETDAKDQSEKDTLSRHLIDHPYSKSFNRKVSLKPPHKCPRCLKAFSEKEELDVHRRSHVGERPFKCTHCPKAYISEKVLTNHIQSHTGYRPYKCSYCPRSFQEKAFLERHLPIHTKERPHKCPECPKSYFIPNNLKIHIRTHTGERPFKCSLCPKTYTSRGVLKLHSRTHTGERPFKCSECPKSFVESAGHRTHMIMHSDERPFQCSRCSKSFKIRRTLASHTRTHTGVRKFQCSQCSKAFVEKHALTKHLLTHTGERPYKCDHCPRSFKQNISLKKHLKKHPDYRPHICSYCSEPFQEKADLDRHLTTQADCSKKFEHEITVKNHTSSQSQKTKDPILKQSYHCDHCTRSFKQKTSLTKHLKKHPDCRPHISSHCSESFQEKADLDEHLTDCSKSFELEISVEPQEHQIFNHTGERPYKCDHCPRSFKHKTSLTNHIKKHPDCRPHISSHCSESFQEKADLDEHLTDCSKSFELEISVEPQEHQILNHTGERPYKCDHCPRSFKHKTSLTNHTQKHPDCRPYVSSHCSESFQEKADLDEHLTDCSKSFELEISDEPQEHQILNHTGERPFKCDHCPKSFKHKPSLTKHIQNHPDYKCELCFKCFFKKSHLREHTYTHIDDEPFQCPQCAKTFKEQEALETHIQTHAEERIYTISDCYPKVSVFRCPHCSKTFPEYANLRYHLYSHANARPYHCFLCRATYTQLRSLKEHLLSAHNIEDKRSYRRPSGYTTKFREHYHL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
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90% Identity
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80% Identity
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