Basic Information

Insect: Drosophila subobscura
Gene Symbol: -
Assembly: GCA_008121235.1
Location: NC:3831568-3838339[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 1e-05 0.0006 19.7 4.0 1 23 288 310 288 310 0.99

2 15 1.7e-05 0.001 18.9 3.5 1 23 316 338 316 338 0.99

3 15 3.3e-06 0.0002 21.2 2.0 1 23 344 366 344 366 0.98

4 15 6.1e-05 0.0036 17.2 1.8 1 23 372 394 372 394 0.97

5 15 7e-05 0.0042 17.0 0.4 1 23 400 422 400 422 0.95

6 15 2.8e-05 0.0016 18.3 0.2 1 23 428 450 428 450 0.98

7 15 1.4e-06 8.3e-05 22.4 3.2 1 23 456 478 456 478 0.98

8 15 6.9e-06 0.00041 20.2 0.7 1 23 484 506 484 506 0.99

9 15 0.00045 0.027 14.5 1.2 2 23 890 911 889 911 0.97

10 15 0.00054 0.032 14.3 1.7 1 23 917 939 917 939 0.96

11 15 4.8e-07 2.9e-05 23.8 1.0 2 23 946 967 946 967 0.96

12 15 3e-07 1.8e-05 24.5 1.5 1 23 973 995 973 995 0.99

13 15 0.00039 0.023 14.7 4.8 1 21 1001 1021 1001 1023 0.94

14 15 2.5e-05 0.0015 18.5 0.3 1 23 1029 1052 1029 1052 0.97

15 15 1.5e-06 8.9e-05 22.3 0.6 1 21 1058 1078 1058 1079 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	1e-05	0.0006	19.7	4.0	1	23	288	310	288	310	0.99
2	15	1.7e-05	0.001	18.9	3.5	1	23	316	338	316	338	0.99
3	15	3.3e-06	0.0002	21.2	2.0	1	23	344	366	344	366	0.98
4	15	6.1e-05	0.0036	17.2	1.8	1	23	372	394	372	394	0.97
5	15	7e-05	0.0042	17.0	0.4	1	23	400	422	400	422	0.95
6	15	2.8e-05	0.0016	18.3	0.2	1	23	428	450	428	450	0.98
7	15	1.4e-06	8.3e-05	22.4	3.2	1	23	456	478	456	478	0.98
8	15	6.9e-06	0.00041	20.2	0.7	1	23	484	506	484	506	0.99
9	15	0.00045	0.027	14.5	1.2	2	23	890	911	889	911	0.97
10	15	0.00054	0.032	14.3	1.7	1	23	917	939	917	939	0.96
11	15	4.8e-07	2.9e-05	23.8	1.0	2	23	946	967	946	967	0.96
12	15	3e-07	1.8e-05	24.5	1.5	1	23	973	995	973	995	0.99
13	15	0.00039	0.023	14.7	4.8	1	21	1001	1021	1001	1023	0.94
14	15	2.5e-05	0.0015	18.5	0.3	1	23	1029	1052	1029	1052	0.97
15	15	1.5e-06	8.9e-05	22.3	0.6	1	21	1058	1078	1058	1079	0.96

Sequence Information

Coding Sequence: ATGATGACGACCAAGGCTGGGAGTGTGGTAATGAATTGCCGCACCTGCACACGAGCCTGCAAGCTGTATAAATCGCTGCAAGATGAGATCGAGATTGGCACCGAGGGCACCACCACACTGGCCAACATGCTGAACTATTGCTCGAGCCTATCCTTTGAGCCGGAAGACGGCGAGACGATGCCGCAACACATCTGCCAGAACTGCTTGCAGCTACTGGAGCAAGCAGTTGCGTTCAAGCGCATGGTTATCGACTCGGACGAGCTGCTGCGCCAGGGATTGAACGAGGCCAACGATGCCTTCGATGAGTACGTCACAGTTGAGATGCTGACCGACGTAGAGGCGGACAACACCAAGCCGGACTCATCCACCACGGACGAGTCGCCGGCCATCATGTTGGAGAATCTTAACGAGCTGCAACAGGGCGAGGAGGAATTCGTCATCGAGGAGGTGGCCGAGCAGGAGGATGAGCAAGAGGACGAGCATGAAATAGAAGAGGCTGAACAGCTTCAgctggtggcagccacagccgagcATTTAGAGATTGAGACCGTGCACGGATACCAGCAGGGAGGCATTCAGTATGTGATCAAGAATGAGTTCGGCTCCCTGGACACCGACGAGGATGAATATGAAGTGATCGacgaggcaacagcagccgatTTGCTCGATGAACGTATGATAGTGATACACGCCGAGGATGCCATCGAGGAGATTGGCGAAGAAGGCCTGGAAATGGTCGAAGAGGAAGCAGAGGAGATGTTGACTTGCGAGGAAGAGGAGATCGAGTGCGATGTTGAGGAGGCGGACTACTTGGATGAGTCAGTGGAGGAGTCGAGCCAACTGCCCAGCGAGCCGCTGCCGTATGTCTGCAAAGTGTGCCAAAAGCCATTCCGCCAGCAATGCCGCCTCAATCAGCACATGCGCTCGCACATCCACGAGAAGCTCTACCGCTGCGACGAGTGCGGCAAGAAGCTGAAACATTTGCGCAACTTCAAGGAGCACATGCTCACCCATTCGAATGTCAAGCCGCATCAGTGCCCCATTTGTGATCGCTTCTATCGCACCACATCCAGCTTGGCCGCCCACAAGCGCACCCATGCCGAGGAAAAGCCACACAATTGTGAGCAGTGTGGACGCGGCTATGCCGCCTTGGATCATCTCAAGCGTCACATGCTCACGCACACCGGCGAGCGTCCGTATGCTTGCGATTTGTGCGACAAGGCCTACTACGACTCGTCGTCGCTGCGGCAGCACAAGGTGAGCCATACGGGCGCCAAGATGTTCACCTGTGAGATATGCGGCGTGGGATTGTCGCAAAAGTCCGGCTACAAGAAGCACATGCTTGTCCACTCTGGCGCAAAGCCGCACAAATGTCACATCTGTGGACGTGCCTTTACATTCACCAGCAATCTCAATGCCCACGTTCGCCTGCATTCCGGCGATAAGCCATTCAAGTGCGAGATCTGCAGCAAGGCATTCCCCACCAAGAAGCGTCTCGTCAGCCACCTGCGTGTCCACAACAAGGAGTCGCGCTCCAATggtgtcagcagcagcagcaacaccgcCAGCATGCCCGTGGCTAATCTGCGCCAACGCGCAGTTGTCAACCAAATGCCCGACATAACTGACCAAAAGGTGTCCAACTCAAAGGTTGTGGTGGTGCTTTTGCGTGGCATCGCGCACCAGACGATACATAATGTAGCCATGCGGATCGAGTGCATCCAGTATGGGGAACACAGTCATGCCCTGCTCAGCCGTGAACACGACAATTTCGAACTCTTTTGCCAGTTCGGCAAGAAAGTGATCGACACCAGGGCGCTTCTTGAAGCGCCAACCAGTTTGATATGTCCAATCCGGATGCACCAGCACGTCCTTCATCTCCAGGACAAGCaaagtgaaaaaaaaacacattgtAACATGTCTTCGTCGAATGGCACTTGCATAGCGCACACCTGTCGCGTCTGCTATGTGCCCGCAATGAAGAGCTACCAACTGTTCAAGCCAAGCCTGGTGTGCGGCCAACTCACAACGCTGGCTCAGGTGCTCAGCTACTGTGTGGGCATCGATGTGCTCGAAGTGGAGAACTATCTGCCCGATCACATATGCAGCGGCTGTGCCGAGAACCTAGAGAAGGTCATGGACTTCAAGGAGAAGGCACGCGGCATCGATAAGATCCTCAGAGAGCGTCATCAAAGGAGGAGCACCGCCAGCGTCAATCTGCGCTGGAACAGTGAGGCGATGGTGCTTGAGCCGGATCCAGACGAGGGCAACTTGCTCTCCGTGTGCGATATTATTGAGGAGGTGCCCGAGGATGATATGCACATGGCAGGCCACATTCCAGAGGAGCAATATCAGATAAgccaagtgcagcagcagcatcagcagcagcagaaactggAGGAGCGGCAGCTGTTGCCTTGGCAGCAGATAGCTGCGGAGAAGGAAACGGAcgaggagggggagggggaggacGAAGAGGAGAAtgaagaagaggaggagcagcagcagcaggaggaggaggaaagtGAGGAGACCAgcgaggaagagcagcagcagcagccgaagaaggagaagcggcagaaggagcagcggcagaaggagcagcagccaccagctgcCAAAACACGCAAACAAACCCGCAGACCAAAGCCCAACTCCGCGCAGTTGCAGTGTCCGATCTGCAATAAGCAGCTGAGCACAACGACATCGTTCAAGTATCACATGCAGCTGCATGGCGACATCAAGCCATTTGCCTGCCACATCTGCGGGGAATCGTTCAAGACACGCAACGCCTTTGATGGCCACAAGACGACGCACGATCCAAACAATCCCAACACATGCCACATATGCGGCAAGGTCTACAGACAAGCCTCATCGCTGCGCACCCACATGCTGGCGCACAAGGGCCTCAAGCCGTACCAGTGTCCGCAGTGCGGCAAGCGTCTCACCCAGAAGTCTGGCTACAAGAAGCACATGCTGACGCACACCGGCGAGATGCCGCACTCCTGCGACATTTGCCAGCGTTCATTTCGATTTTCGAGCAATTTGATTGCGCACAaacgctgccacagccaggagAAACCGTTCGAGTGTCAGGTGTGTCCCAAGCGCAGCTTTGCCAGCAGCTCCGATCTGACGCGACACATGCTCGTCCACTCCGACGAGCGTCCCTTCAAGTGTCTCGATTGTGGCAAAACCTTCAAGCGTCAGATCTCCCTCAGTATTCACatgaaatcaaagaaaacagCGGCCATGGAATCGTCACCAGAGTACGATGAGGAGAACTAG
Protein Sequence: MMTTKAGSVVMNCRTCTRACKLYKSLQDEIEIGTEGTTTLANMLNYCSSLSFEPEDGETMPQHICQNCLQLLEQAVAFKRMVIDSDELLRQGLNEANDAFDEYVTVEMLTDVEADNTKPDSSTTDESPAIMLENLNELQQGEEEFVIEEVAEQEDEQEDEHEIEEAEQLQLVAATAEHLEIETVHGYQQGGIQYVIKNEFGSLDTDEDEYEVIDEATAADLLDERMIVIHAEDAIEEIGEEGLEMVEEEAEEMLTCEEEEIECDVEEADYLDESVEESSQLPSEPLPYVCKVCQKPFRQQCRLNQHMRSHIHEKLYRCDECGKKLKHLRNFKEHMLTHSNVKPHQCPICDRFYRTTSSLAAHKRTHAEEKPHNCEQCGRGYAALDHLKRHMLTHTGERPYACDLCDKAYYDSSSLRQHKVSHTGAKMFTCEICGVGLSQKSGYKKHMLVHSGAKPHKCHICGRAFTFTSNLNAHVRLHSGDKPFKCEICSKAFPTKKRLVSHLRVHNKESRSNGVSSSSNTASMPVANLRQRAVVNQMPDITDQKVSNSKVVVVLLRGIAHQTIHNVAMRIECIQYGEHSHALLSREHDNFELFCQFGKKVIDTRALLEAPTSLICPIRMHQHVLHLQDKQSEKKTHCNMSSSNGTCIAHTCRVCYVPAMKSYQLFKPSLVCGQLTTLAQVLSYCVGIDVLEVENYLPDHICSGCAENLEKVMDFKEKARGIDKILRERHQRRSTASVNLRWNSEAMVLEPDPDEGNLLSVCDIIEEVPEDDMHMAGHIPEEQYQISQVQQQHQQQQKLEERQLLPWQQIAAEKETDEEGEGEDEEENEEEEEQQQQEEEESEETSEEEQQQQPKKEKRQKEQRQKEQQPPAAKTRKQTRRPKPNSAQLQCPICNKQLSTTTSFKYHMQLHGDIKPFACHICGESFKTRNAFDGHKTTHDPNNPNTCHICGKVYRQASSLRTHMLAHKGLKPYQCPQCGKRLTQKSGYKKHMLTHTGEMPHSCDICQRSFRFSSNLIAHKRCHSQEKPFECQVCPKRSFASSSDLTRHMLVHSDERPFKCLDCGKTFKRQISLSIHMKSKKTAAMESSPEYDEEN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -