Basic Information

Insect: Drosophila sturtevanti
Gene Symbol: -
Assembly: GCA_018150375.1
Location: JAECWJ010000289.1:854988-862741[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.05 3.5 8.2 1.8 1 23 806 828 806 829 0.95

2 8 0.007 0.5 10.9 0.2 1 23 834 857 834 857 0.98

3 8 0.12 8.7 7.0 2.3 1 23 1098 1121 1098 1121 0.93

4 8 5.7e-05 0.004 17.5 0.7 1 23 1129 1151 1129 1151 0.98

5 8 0.0001 0.0073 16.6 0.3 1 23 1158 1181 1158 1181 0.97

6 8 1.3e-05 0.00089 19.5 1.4 1 23 1187 1209 1187 1209 0.97

7 8 3.9e-06 0.00027 21.1 0.8 1 23 1214 1236 1214 1236 0.99

8 8 0.001 0.071 13.5 1.7 1 23 1242 1264 1242 1264 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.05	3.5	8.2	1.8	1	23	806	828	806	829	0.95
2	8	0.007	0.5	10.9	0.2	1	23	834	857	834	857	0.98
3	8	0.12	8.7	7.0	2.3	1	23	1098	1121	1098	1121	0.93
4	8	5.7e-05	0.004	17.5	0.7	1	23	1129	1151	1129	1151	0.98
5	8	0.0001	0.0073	16.6	0.3	1	23	1158	1181	1158	1181	0.97
6	8	1.3e-05	0.00089	19.5	1.4	1	23	1187	1209	1187	1209	0.97
7	8	3.9e-06	0.00027	21.1	0.8	1	23	1214	1236	1214	1236	0.99
8	8	0.001	0.071	13.5	1.7	1	23	1242	1264	1242	1264	0.99

Sequence Information

Coding Sequence: ATGATCAGTAAAGATGATGGACTACCTCAAGAGATTTGCCGCCAGTGTAAGGCACAATTCCTTATGGTGGCGAAATTTCGTCGACGATGTGTACGTATGCAGCAACGTCTGCAGGATTATGCCCAAGAGTTATCCGATAAACAAGAGGCAAGACTGAACATGCGGCAACAAAAGAGAAAGAGAGAACAGGAACAGGCGCCGCCACTACAAGTACAAGTTCAGTTGCAACAGCAGCACGAACATAATGTTTCCTATATTGAAATACCGAAAACAAATATAATGGATTGTAAGCGTCATCTTAGATCAGAATCTGAAGGGGAATCGCCGCCAGAATCACAGCCAAAGGAAGATAAGACTGAAGTAGAGACTGAACTGCCGCCACCTAAGATTCGACGTTTGATGTTACGATTGCGTAAATTACGCAGAGGTTCAACTGGAGAGGAACAGGAACAGGAACAGGAACATGAACGGGAAGGGGAACGGGAACGGGAACAGTCGTTAGACTCATCATCATCTACACCAATGTGTGACATCTATGAGAAGATCAATATTCCATGGAAAACAAAAGCAGCTAGAAAACAATTATCCGAAATACACTCCGATGCCTCATCTCAAGCAGAAGTCGAAGATCCTAGTACAGGCAGCGAAGTATCGGTGGATCCATGTTTTGGTTTCGAGAGTGATAGCAATCCATCATCTTCAACATCAACATCTACTTCGTCAACATTAAAGTTTCCCAAACGGCCTCAGGCTAGAGTTGTTGGTGGTGTTCGTCGTGGCCGCCGGATACGTAACATTCCCACATACACGGCAGCCAAACGTCAGAGGCGTAACATCACCATTAAGAAAATGGCTACAGCGACGGATGTGATCGCAGAACATAAAGTTAAAGACAAAGATCAGAAGCAAGAAACAGATGACGGACGAAATTCCCCGGAGCAGGAACCTGCGGCTCTAACTAAAGACGAGCTATCATCACCCATGGACAGTGAGACGGAAACAATACCTCCTTCTAGTAGTTTGGATACACCACAAAATGTCCAAGCTGATGAAATAAAAAAAAATCCAGAGCCCGAGATTGATAACTCTAAGCAAAATCATCAATCGGATAAGATAAATTGTGAAAAGGAGTCGTTAACTTCAAATGCCATAACAGAGGATACGAAGGAAACAAAAATAATTGAGATCCCTAAGGGAGAATCAACAAATGATCCAGAAAAGTCATCTGAAGCGGAACCATGTTCGGTGTCCTCCACATCCACCAGCCAAATAGAAAAACCAGAGCAATCCGACAATCTAAAGCAATCAGAGCAACCAGAACTTGTGGTCAGCATACCTCTTGATAAACTCACTGAAGATCTCCAGCGTAAACTAACTATTGGTAGAGATGAAAACGAGGAGGAGGAGCAGCAGCAGCAGCAGCAGCAGGAGGATGAGGAGCTGGAAGGGATTGAGTCATCATCGACAAATTCGAAGGAGGACAATAATAATAATGCGAATAATGAAAATTTTTGTCAGAGTGCTACAGCAGATAGCTTCAATTCTGTTGTGGCACTCTCAAAACCACATATTGAAGCAAATTTAAAAGAAACGGATGGACCAATTGATGTGGCCGAAACTCCACCATCTCCCCCATTACCAAAAGTTGACGCAGCGTTAGAGGATCGAATGCCAGAGCCAATAAGAACAGCACCAACACCCATGGATTTTCTGGCTGAATTTGAGAAGCATTGCGAAATGCGATCTCAGACAATGTCGTCGCCACCAAGTTCTCCGGTCCCATCACCACCACCACCACCACCCCCTCTCAATGATTTATCTGATAAGGAACAATTGGAGGTTGAAATGAATGATGTTGAGACGACATTGAATGGTATACTTAATGAAATGCAGGATCAACATATATATCCACCCACATGTCCCCATATAGATGAGTTTCTAACTCCCGCCGATTATGATCCGCTTAATGAACAGAATGAATCCAATTCTCCCCTGGCTGAGGTAAATGAGGATAATGAGACCACAACTGGACAAAAGGAAAGCCATCAGGCAACGGCAACAAATGGTGACATCTTTAATAGTAATAATTTTACCAATGAATTAATTGGTTTTCAAAATGATATACCATGTTTTGAGAATATTGAAGCAACACCTGAATCCCAACAGAATTTGCAATTGGAATTGACGCAGCTGCTTAACGATTTGCAACCGACGACGGCGATACCAACTGTGGCAGTTGAACAACAAACAGAAACCCAAATTGTTCAACCTATTACCAACTATGATCAGCTTATCCAATTGCCAAATGGAACATTGGAGTCCTTGAAATGTCGCTTTTGTCAAAATGGACCGCGTTTTTTAAATAGTTTAGAATATAGTCGTCATATAATGGAGCTACATCCAGCAGTGGCTCCCTTTAATTGCCCTCATTGCCCATTAGCCTTTCCCGGTCGTAATAAACGCTCCCAGCACATTCTCAGCCATCATGTGTTGCAACAATATCAATGCGGACAATGTACACAGGTTTTTCCTGCTCAGCGTGCATTGGATTTGCATATACAACGGTTTCATATGACATTACCAGCACAACCAGCCACAATACATTTGGGATCAAATGGTGTTGGTGGTGTACGTGTTGAAGATGTCCAATTACAAATTTCGAATAATGAGCAACCAATGACAATAACCCAACCACCAGCTCTGCAAATTTATGCAAATGCGACACCAAAACCTAGAAAACCCCGTATTATTTGCTGTCCAGATTGTGACAATTGCACTACGGGTCAGCATCATATTAGTGGAGGAGGAGGGGCAGGAGCAGGAGCTGATGGTGGTAGTGGTGTTTGTGTTGGTGCTGGTGCTGGTGTTAGTGTGAGTGTTAATGGAGAACTTGGCAATGGATCATTTGAAGAATTGACCAATTTGCAACCACCGCCGATGGTCTTAACGCCGCCAACAACAATTGCATCGATGCCGTCGCCACAACCAATAAGCGCAACACCACATCTAACATTACCCTCACCGGAACAATCCGAACCGGACTCAACGACAACGTTACGTCAGTTCCGTAAACGAAATTGCATGACTGCCACACCCATAGCCTCACCGTCACCCTCTTCGTCGCCATCGTCATCGACAATGATGGATCCAATATCTAACAATGCACCAACAAATGCCACAAATACCAGTAGCACAACAAGTAGCTGCAGCAAAAGCAAAGGAAAAAGCAACACCAGCTCCGCCTCCACCTCCACCTCCACTTCCCTTCAAGTAAGCGATTTACGTGGCAGTCATCAGTGTATCTATTGTGAGGAACGTTTTACCAACGATATTGCCCTGCGCAAACATCATCAGTTGGCCCATGGTGCACAGACCACAATGCCTTTTGTATGCACAATTTGCAAGCGTGGTTATCGGATGCGAACCGCTTTAAATCGCCACATGGAGTCCCATGATGCCGAAGGTAGACCCTATGAGTGCAATCTATGTCGAGTGCGTTTCCCACGACCATCCCAGTTAACATTGCATAAAATAACAGTTCATCTGCTGTCCAAGCCACACACATGCGATGAGTGCGGCAAACAATTTGGTACGGAGAGCGCCTTGAAGACGCACATTAAGTTTCACGGTGAGCTTGGTTACCAATGCGATGAATGCGATCAGAGATTCGTTTATATTGCAGAATTACGCAAACATCGCCGGACACATAAACGCGAACAGTTTTACAAATGTGAATTCTGTCCGCGATCTTTCTTGCGTTTTACGGCATTTCGTGCTCATATGAATTCCCATTTGCCGCTGGGCGTATTCCTCAATGAAGACACTGGCTTGATGTCCTCCACATCTTCCACGAACAACTGCAGCGCGGAAAAATCGGATAATCTAAATACACTCAGCATAACAGAGGAATCAAAGGTGATAGAGACAAAGGAGCAGCCACAATTGGATGAACCATCGTTAGCACCAACTACATCAATGCAGCTAACGATGGTGGAAAGTAGTGCCGGGAACAATAATGCCACAATAAATCTTCCATCAGAAACCATTGCCACGACGCCATAA
Protein Sequence: MISKDDGLPQEICRQCKAQFLMVAKFRRRCVRMQQRLQDYAQELSDKQEARLNMRQQKRKREQEQAPPLQVQVQLQQQHEHNVSYIEIPKTNIMDCKRHLRSESEGESPPESQPKEDKTEVETELPPPKIRRLMLRLRKLRRGSTGEEQEQEQEHEREGEREREQSLDSSSSTPMCDIYEKINIPWKTKAARKQLSEIHSDASSQAEVEDPSTGSEVSVDPCFGFESDSNPSSSTSTSTSSTLKFPKRPQARVVGGVRRGRRIRNIPTYTAAKRQRRNITIKKMATATDVIAEHKVKDKDQKQETDDGRNSPEQEPAALTKDELSSPMDSETETIPPSSSLDTPQNVQADEIKKNPEPEIDNSKQNHQSDKINCEKESLTSNAITEDTKETKIIEIPKGESTNDPEKSSEAEPCSVSSTSTSQIEKPEQSDNLKQSEQPELVVSIPLDKLTEDLQRKLTIGRDENEEEEQQQQQQQEDEELEGIESSSTNSKEDNNNNANNENFCQSATADSFNSVVALSKPHIEANLKETDGPIDVAETPPSPPLPKVDAALEDRMPEPIRTAPTPMDFLAEFEKHCEMRSQTMSSPPSSPVPSPPPPPPPLNDLSDKEQLEVEMNDVETTLNGILNEMQDQHIYPPTCPHIDEFLTPADYDPLNEQNESNSPLAEVNEDNETTTGQKESHQATATNGDIFNSNNFTNELIGFQNDIPCFENIEATPESQQNLQLELTQLLNDLQPTTAIPTVAVEQQTETQIVQPITNYDQLIQLPNGTLESLKCRFCQNGPRFLNSLEYSRHIMELHPAVAPFNCPHCPLAFPGRNKRSQHILSHHVLQQYQCGQCTQVFPAQRALDLHIQRFHMTLPAQPATIHLGSNGVGGVRVEDVQLQISNNEQPMTITQPPALQIYANATPKPRKPRIICCPDCDNCTTGQHHISGGGGAGAGADGGSGVCVGAGAGVSVSVNGELGNGSFEELTNLQPPPMVLTPPTTIASMPSPQPISATPHLTLPSPEQSEPDSTTTLRQFRKRNCMTATPIASPSPSSSPSSSTMMDPISNNAPTNATNTSSTTSSCSKSKGKSNTSSASTSTSTSLQVSDLRGSHQCIYCEERFTNDIALRKHHQLAHGAQTTMPFVCTICKRGYRMRTALNRHMESHDAEGRPYECNLCRVRFPRPSQLTLHKITVHLLSKPHTCDECGKQFGTESALKTHIKFHGELGYQCDECDQRFVYIAELRKHRRTHKREQFYKCEFCPRSFLRFTAFRAHMNSHLPLGVFLNEDTGLMSSTSSTNNCSAEKSDNLNTLSITEESKVIETKEQPQLDEPSLAPTTSMQLTMVESSAGNNNATINLPSETIATTP

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -