Dstu007811.1
Basic Information
- Insect
- Drosophila sturtevanti
- Gene Symbol
- -
- Assembly
- GCA_018150375.1
- Location
- JAECWJ010000317.1:10463398-10466677[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 17 0.023 1.6 9.3 5.2 2 23 232 254 231 254 0.95 2 17 2.7 1.9e+02 2.7 0.1 1 23 259 284 259 284 0.94 3 17 0.094 6.6 7.3 2.4 2 23 295 316 295 316 0.93 4 17 9.1 6.4e+02 1.1 0.3 3 23 357 378 356 378 0.89 5 17 0.0016 0.11 12.9 0.7 1 23 384 406 384 406 0.97 6 17 0.00083 0.058 13.8 2.0 1 23 414 437 414 437 0.98 7 17 5.3e-05 0.0038 17.5 0.3 2 23 442 463 441 463 0.97 8 17 0.0017 0.12 12.8 0.7 1 22 511 532 511 535 0.91 9 17 0.44 31 5.2 1.2 3 21 542 560 542 561 0.89 10 17 0.042 3 8.4 0.9 1 23 580 605 580 605 0.96 11 17 0.019 1.3 9.5 2.5 2 23 633 655 632 655 0.94 12 17 0.015 1.1 9.8 0.4 3 23 662 683 660 683 0.92 13 17 0.0072 0.5 10.8 0.3 2 23 687 709 686 709 0.94 14 17 1.5e-05 0.0011 19.2 2.0 1 23 715 737 715 737 0.98 15 17 0.002 0.14 12.6 2.9 1 23 741 764 741 764 0.94 16 17 4.1e-05 0.0029 17.9 1.2 1 23 770 793 770 793 0.97 17 17 0.005 0.35 11.3 0.1 1 23 797 825 797 825 0.91
Sequence Information
- Coding Sequence
- ATGGACATGGACAAAAAGTTACAAAATTTGTCTCATAAAATCTGTCTGCATTGTACAGCCCACAATCCAAAATTAAAATACCATGAAATTTTTAAAGGTCTTGGCGCGGAAATTGGATTGCAGGAGTTGTTGGCTAAACATTTTCATTTTGTGGTCGAAATTTCCACAAAGCCTCAGTTGCTTTGCGAGGTGTGTGTCAACAGTTTAATCCAATTTTTTGACATCGATGAATTGGAACGGGAGAAAAATGATGCATCTATTGCAGCGGAAAAGGTTCAACGCATTGTGTGCCAAAGACCAACTAATCAGACCAGTTATGTAACACGTACATCCAAGAAGTCCAACAAAGCTACCGAGGAAAAGTCAATCGTAGATGAGTCCGGCACATATGAGTTTATATTTAAATCAGACGATGTATCTTCCACTTCGGTGTTGGAAGAGGAGGAAGAGCAAGAGAATGTGGAAGTAAACGAAGACATAACCAAGTCAGATCAAGGAGGTAATGAGGTTGGTGTGGATTTTGAATTGGAGAGTGATCAGGAAGTGGAAGCAGATTTACAATCCAAGCCAGATGAAGACGAAGATGGCATAGAAACAGATAGCAATGTTATAGATGACATTGATGATTTATATGCCTATTTGGCCACAGTAGTGAAAACGAAATTTGAAAACTTATCATTTGAGTGGAGCACGAGATGCAAACATTGTTCTTTGCCATGTTCCAACTTTCAGAATCTACTTAACCATATGATGCAGCAACACAAAGATTGTCCTTTTGAGTGTCCATTTGAGGGTTGCGTGGTCAAACTAAAGGACAAACAATTTCTAGCCATGCATTTGGTTATGCTGCATGGTCCAGTAGTCAATATACCGATATATGGCAGTTGTCCGGAATGCAAATTAAAATTCTCCAACATTTTACAATATAATAAACATTCCTGTGCCCATGTGATCAAGAAGAAACGTGGCATCCGTCTATATTGTGAAATGTGTTCCATTGAGTTTCCCTCATGGAAACGTTTCAGTTTCCATAATCAATTTCATCTGGAGAGGCACAGACCTCGAGCGTGTTTTGTCTGTAACTATGCCGACACCAATATCGATGATCTCTTCCAGCATTTACACTATGCCCATGAGCCAGAGAACACATTCGTCTGTAAATTATGTGACCGGACATTTCGAGATGAAGTTGTTTTTCTGGAGCACAACAAAACGCATTTAAATGCCAGCAGCAGCACTTACACCTGCAATGAATGTTTCCTCAATTTTGATACTCGGAGTCGATTTAATGGACACATGCGTTCAATGCATGGCACTTTCATCAGTTGCGAGATCTGTTCAAGGGAATTTGCCAGCGAATCCACCTATAATGTGCATATGAAAAAACATTTGATTATCGAACGTGATGTCCATATTTGCCGAAATTGTGGCCAACTGAGTGAACATGAGAATAAAATGCTGCAGCATACAGAATCAGAATCGTCCAACTGCCACAAATCAGATATATATACTGATACATTACGCAATGCTTACATATGCGAATATTGTTCTAGTTATTTTCGTGAGAAATCGGATTTGAATAATCATCGCCAGTCGGGCGTACATAATAATGGTTTATTTTGGTGCCAGCCTTGTTCAAAGGAATTTACTGATATGAAACTTTATCGTCATCATTTGAGAAACTTCCAACAATTGAAGTCGGATACGGAACATCGAAAATTCGAAATATGCTTGTACTATATGTGTGATCAGAAGGATTGCATGGAATCTTATGCAAATTGGAATTCCTTGTACACTCATAAGCGACGCACTCATAGCAAGAATTCTAATCAGTCCAAAGTAGATCACGAAAGCCAAACCACATCGAAATCAACCGCAAATGGAAAACCGGAATGGCAATGCCAGTTTTGTAAAAAGGAATGCCGCTCCAAGATGTCTCTTTCGGTCCATGTGGCACGCAGTCACAATAATGATAATGTTATCTGTTCCATTTGCAAATCGTCATATAAAAACCAAGCAGCATTGGATAAACATCATGCCTATTGGCATGAACCCATCGAGTGTCCGAAATGCTTTAAGGTTGTTAAAAATCGTCGCAATTACGATACTCATGAGAATGTTGTTCATTCGAATAATAAACGTTATACCTGCGGTATTTGTGAAAAGGGTTTCTATCACAAGAGTGAAATGAAGGCACATCAAAAGCTCCATTCCAATTTGTATAGTTGTAAACATTGCAACTTTACCACTAGAAATAAAACTTCTTTATCGGTTCATGTTATGGGTCAGCATTTTAAACGGTTTGCCTTTTCCTGCAAGATGTGCTCGAAGCGGTTTGGTCGACGCCAGGGATTGGCCACTCATATGCAGCGGGTGCATGGGACAAAGTATTCCTGTGAGGAATATTTTATAGGCGGTTGTAATCGGAGTTTTGCCTCCACTGCTTTATTAAGTCAGCATGTAAAGAAAGTCCACAAGGGAACTATATTTTTACCCGACGATATACTGGAGGAAGAATTTGGGGAGCAGGACGAATTGGTGGAGCTAGAGGATGAAGAGTTGGATAACGAGAATGGACCGACCACGTCTAGGAAACGTTATTTTCAAATAAATGATACCAAAATTGAGTTTATCGAAGAGGGTGTCGAAGATATTGAGGAACTTATAGACGAGGATCAGGAGATGGAAGAAGTTGACGACGATAAAAAGAGTTAA
- Protein Sequence
- MDMDKKLQNLSHKICLHCTAHNPKLKYHEIFKGLGAEIGLQELLAKHFHFVVEISTKPQLLCEVCVNSLIQFFDIDELEREKNDASIAAEKVQRIVCQRPTNQTSYVTRTSKKSNKATEEKSIVDESGTYEFIFKSDDVSSTSVLEEEEEQENVEVNEDITKSDQGGNEVGVDFELESDQEVEADLQSKPDEDEDGIETDSNVIDDIDDLYAYLATVVKTKFENLSFEWSTRCKHCSLPCSNFQNLLNHMMQQHKDCPFECPFEGCVVKLKDKQFLAMHLVMLHGPVVNIPIYGSCPECKLKFSNILQYNKHSCAHVIKKKRGIRLYCEMCSIEFPSWKRFSFHNQFHLERHRPRACFVCNYADTNIDDLFQHLHYAHEPENTFVCKLCDRTFRDEVVFLEHNKTHLNASSSTYTCNECFLNFDTRSRFNGHMRSMHGTFISCEICSREFASESTYNVHMKKHLIIERDVHICRNCGQLSEHENKMLQHTESESSNCHKSDIYTDTLRNAYICEYCSSYFREKSDLNNHRQSGVHNNGLFWCQPCSKEFTDMKLYRHHLRNFQQLKSDTEHRKFEICLYYMCDQKDCMESYANWNSLYTHKRRTHSKNSNQSKVDHESQTTSKSTANGKPEWQCQFCKKECRSKMSLSVHVARSHNNDNVICSICKSSYKNQAALDKHHAYWHEPIECPKCFKVVKNRRNYDTHENVVHSNNKRYTCGICEKGFYHKSEMKAHQKLHSNLYSCKHCNFTTRNKTSLSVHVMGQHFKRFAFSCKMCSKRFGRRQGLATHMQRVHGTKYSCEEYFIGGCNRSFASTALLSQHVKKVHKGTIFLPDDILEEEFGEQDELVELEDEELDNENGPTTSRKRYFQINDTKIEFIEEGVEDIEELIDEDQEMEEVDDDKKS
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00501293;
- 90% Identity
- -
- 80% Identity
- -