Basic Information

Insect: Drosophila sturtevanti
Gene Symbol: RREB1
Assembly: GCA_018150375.1
Location: JAECWJ010000686.1:6613987-6620095[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.016 1.1 9.7 0.8 1 21 3 23 3 25 0.93

2 12 0.00015 0.01 16.1 0.2 1 23 35 57 35 57 0.98

3 12 0.14 10 6.8 0.7 1 14 63 76 63 80 0.89

4 12 2.3 1.6e+02 3.0 0.5 3 23 204 225 202 226 0.90

5 12 1.1 75 4.0 6.2 2 19 232 249 232 251 0.97

6 12 0.0029 0.21 12.1 0.1 1 23 381 403 381 403 0.98

7 12 5.5e-06 0.00039 20.7 0.7 1 23 413 435 413 435 0.99

8 12 0.00037 0.026 14.9 2.0 1 23 441 464 441 464 0.97

9 12 3.8e-05 0.0027 18.0 0.3 2 23 708 729 707 729 0.97

10 12 0.064 4.5 7.8 6.3 1 23 735 758 735 758 0.97

11 12 0.0037 0.26 11.7 0.5 3 23 874 894 872 894 0.96

12 12 0.00059 0.042 14.2 4.8 1 23 900 922 900 922 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.016	1.1	9.7	0.8	1	21	3	23	3	25	0.93
2	12	0.00015	0.01	16.1	0.2	1	23	35	57	35	57	0.98
3	12	0.14	10	6.8	0.7	1	14	63	76	63	80	0.89
4	12	2.3	1.6e+02	3.0	0.5	3	23	204	225	202	226	0.90
5	12	1.1	75	4.0	6.2	2	19	232	249	232	251	0.97
6	12	0.0029	0.21	12.1	0.1	1	23	381	403	381	403	0.98
7	12	5.5e-06	0.00039	20.7	0.7	1	23	413	435	413	435	0.99
8	12	0.00037	0.026	14.9	2.0	1	23	441	464	441	464	0.97
9	12	3.8e-05	0.0027	18.0	0.3	2	23	708	729	707	729	0.97
10	12	0.064	4.5	7.8	6.3	1	23	735	758	735	758	0.97
11	12	0.0037	0.26	11.7	0.5	3	23	874	894	872	894	0.96
12	12	0.00059	0.042	14.2	4.8	1	23	900	922	900	922	0.99

Sequence Information

Coding Sequence: ATGAAATATTTATGCCCCATCTGTGAAGTTGTCTCGGCCACGCCCCATGAATTTACCAATCACATCCGATGTCATAATTATGCCAATGGCGATACCGAAAATTTTACTTGTCGCATTTGCTCCAAGGTATTATCATCGGCTTCGTCCTTAGACAGGCATGTCCTAGTCCATACAGGTGAACGGCCATTTAATTGTCGTTATTGTCATCTGACTTTCACCACAAATGAGGAAAGGATTAAGGAAGAGCAAATTGATTTAGATGATGAAGAGCAACAAGATGTTGCCACATCAATGGATGAGTTGCCATTATTAAAACAAAAACGTCGTCTAAAGACCACGATCAATAATAATATAATAGATGATGATGAAGTAGGTAGAAGAGATAATAGGGATAATGCAGAGGATGCTGATATTGCTGATCCTGATGAGGATGAGAATGAGAATGAGAATGGGGATGAGAATGGGAATGAGAATGGGAATGGGGATGGGGATGAGGATGAGGATGATCGGCGAACAGAAGTGGGAGTGTCTATAACTAGTACACCAGATGTGGCTGCATTATTGGCGGGTGCCTCCAGACCAGGATCACCATCACTATCACTAATCGCCTGTCCCGTTTGCAATTTGGCCGAATTTGAAACCCTGCCCAGTTTATGCCAACATTTGGATCAACATCATTCCGATATTTTGGCCAAATGTCGTGAATGTGAGGTAATCTTTTCCAGTCATAAGCAATTGCAAAAGCATTGCTGTCGTGGATCATCATCAACGGGATTGCCACCACTGCTAAGAGCAATTGAAAAGGAAGCCGAAGCAGAAGCCAAACAGCGTGACGATTTCTTTCATCATTTGTATTTGAAGAGTAAAACGGAAGCCATGTCCGAGGACAATAATGAATTGGCCACATCGCCACCCTCACCGATTAAACATGAACCCAATGATAGTAAAGATTTGGCTGATATACAAAGTATACTCAATATGACCAGTTCCAGTTGTACATCCAGTTTTTTGCGTAACTTTGAACAATCGGTCAATACGCCCTGCTCATCGAGTCAATATAGTTTAGATGGTCGGGATCAGGAGGAGGAGGCTCAAGATGTTTTCACATCAGAATTTCGTCGTATGAAATTGCGTGGCGAATTTCCATGTAAACTCTGTACAGCGGTTTTTCCCAATTTGCGTGCCCTCAAGGGACATAATCGTATGCATTTGGGTGCCGTTGGACCAGCGGGTCCCTTCCGTTGCAACATGTGCCCATATGCGGTATGCGATAAAGCCGCTCTGGTGCGTCATATGCGTACCCATAATGGTGATCGTCCGTATGAATGTGCCGTATGCAATTATGCCTTCACAACAAAAGCAAATTGTGAGCGCCATTTAAGGAATCGTCATGGAAAGACAAGTAGGGATGATGTTAAACGGGCCATTGTCTATCATCCCGCTGAGGATGCCAGTTGCGGTGAGGGTGAGGGTAAAATTCGTATGAGTGAAGCCGATGAAAGTTATCGTTCGTCATCACCACCGCCATTAGAGACAGGAAATCTTAATATGGATATGGAGAAAACGGTAGAGGATGAGAAACAATCTCGGAAATCTAACAAGGATTTACCTCAAAGCATTGAGAACTTGGCCACAAATGAGGCAGCTAAAAAAGTGGCCGAAACAATTTTGGAGCAAGCGATTAAAGCTGGTAAACCATTATCCATACCCGAAGTTGAGGGAACTTCAGCTCCAACAGTAGCAACAGTTGCTGCTTCATTGCCTCATCAGCCGCCATCTTCAATGAAATCGATGATTGCTCAAGTTGAATCCGTGGCCAAGTCACTTAAAGATGTGGCCAGTTCACCATTTAATAAAGATGAATCTCCACTATCGGATTTGGTGCCTGTATCGAAGCTGGTGGATAATGCAACCAGTAATCAATCAATGCAAAGTTTCACCAGCTATTTTCGTCCCAGCGATGTGGCCAATCATATGGAACAAAGCGATGAGGAGGGTCTTGTTGCCTCTGGCAGTGCCAGCGAGAGCAATAATTCCGGTACCGAAGATGTCACCAGCAGTAGCAGCAGTGGCCAGGAGCCAAAGAAAAAATCGGCTTACAGTCTGGCGCCCAATCGTGTCTCCTGTCCCTACTGTCAGCGCATGTTCCCCTGGAGCAGCTCGCTCAGACGGCATATTCTAACCCACACGGGACAGAAACCCTTCAAATGCTCCCATTGCCCTTTATTATTTACCACCAAAAGCAATTGCGATCGTCATTTGTTAAGAAAACATGGTAATGTTGAATCGGCCATGTCTGTATATGTCCCCACCGAGGATGTAAGTGAACCGATACCAGTACCAAAATCAGTGGAAGAGATTGAATTGGAGGAGCAAAGAAAGCGATTGGAAGCGGAAAAAGAAAAGGCCGAATTGGAACGGGAACGAGAACGTGAAAGGGAATTGGAACGAGAGCTAGAACGAGAAAGGGAAAAGGAGCGTGCTATTGAAACAGAAGAGCCCACACATAATGCTAATCATCCAACAGCAGCAAACCAATCCGATGATGAGTCTCTGGGCATTGGCAATGGCCGTACTGGTTCCGGTAAATATCCCGATTATAGTAACCGTAAAGTCATATGTGCCTTTTGTGTTCGTCGTTTTTGGTCGACCGAAGATTTGCGTCGTCATATGCGAACCCATTCGGGTGAGCGGCCATTTCAGTGCGAGATTTGCCTTAGGAAATTTACATTAAAGCATAGCATGTTGCGGCATATGAAGAAGCATAGTGGACGATCTCATAATGCTGGTGAAATGCAAGGTCTACTGGACAAGGCGAACGAGTGGCGAGCCAGTCGTTTGGGCGAGCACAAAGAGAATCTGGGTGAAGCAGCAGCAACACCGGCAAGTGCAGCTGGAGCTGTGGCTGGTTCAACGGATCTCATTGGCAATCTGTTGGGCATTAGCGATCAGGGTATATTGAATAAGTTGCTCTCATCGGCAGATGAGGCAGCCAAATTGCTGGGAGTGGACAAGTAA
Protein Sequence: MKYLCPICEVVSATPHEFTNHIRCHNYANGDTENFTCRICSKVLSSASSLDRHVLVHTGERPFNCRYCHLTFTTNEERIKEEQIDLDDEEQQDVATSMDELPLLKQKRRLKTTINNNIIDDDEVGRRDNRDNAEDADIADPDEDENENENGDENGNENGNGDGDEDEDDRRTEVGVSITSTPDVAALLAGASRPGSPSLSLIACPVCNLAEFETLPSLCQHLDQHHSDILAKCRECEVIFSSHKQLQKHCCRGSSSTGLPPLLRAIEKEAEAEAKQRDDFFHHLYLKSKTEAMSEDNNELATSPPSPIKHEPNDSKDLADIQSILNMTSSSCTSSFLRNFEQSVNTPCSSSQYSLDGRDQEEEAQDVFTSEFRRMKLRGEFPCKLCTAVFPNLRALKGHNRMHLGAVGPAGPFRCNMCPYAVCDKAALVRHMRTHNGDRPYECAVCNYAFTTKANCERHLRNRHGKTSRDDVKRAIVYHPAEDASCGEGEGKIRMSEADESYRSSSPPPLETGNLNMDMEKTVEDEKQSRKSNKDLPQSIENLATNEAAKKVAETILEQAIKAGKPLSIPEVEGTSAPTVATVAASLPHQPPSSMKSMIAQVESVAKSLKDVASSPFNKDESPLSDLVPVSKLVDNATSNQSMQSFTSYFRPSDVANHMEQSDEEGLVASGSASESNNSGTEDVTSSSSSGQEPKKKSAYSLAPNRVSCPYCQRMFPWSSSLRRHILTHTGQKPFKCSHCPLLFTTKSNCDRHLLRKHGNVESAMSVYVPTEDVSEPIPVPKSVEEIELEEQRKRLEAEKEKAELERERERERELERELEREREKERAIETEEPTHNANHPTAANQSDDESLGIGNGRTGSGKYPDYSNRKVICAFCVRRFWSTEDLRRHMRTHSGERPFQCEICLRKFTLKHSMLRHMKKHSGRSHNAGEMQGLLDKANEWRASRLGEHKENLGEAAATPASAAGAVAGSTDLIGNLLGISDQGILNKLLSSADEAAKLLGVDK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -