Dstu003452.1
Basic Information
- Insect
- Drosophila sturtevanti
- Gene Symbol
- kipf
- Assembly
- GCA_018150375.1
- Location
- JAECWJ010000408.1:776815-780288[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 17 1.8e-05 0.0013 19.0 2.3 1 23 166 189 166 189 0.97 2 17 1.4e-06 9.9e-05 22.5 0.7 1 23 195 217 195 217 0.99 3 17 4.1e-06 0.00029 21.0 1.2 1 23 223 245 223 245 0.99 4 17 0.0012 0.085 13.3 2.6 1 21 349 369 349 370 0.96 5 17 0.013 0.88 10.1 0.1 3 23 378 401 377 401 0.91 6 17 3e-06 0.00021 21.5 1.3 1 23 407 429 407 429 0.98 7 17 4.4e-05 0.0031 17.8 3.7 1 23 435 458 435 458 0.96 8 17 0.0012 0.084 13.3 6.6 3 23 499 519 498 519 0.95 9 17 1.6e-05 0.0011 19.2 6.3 1 21 522 542 522 545 0.94 10 17 0.007 0.49 10.9 1.7 1 23 583 606 583 606 0.97 11 17 0.00051 0.036 14.5 7.4 1 23 655 677 655 677 0.98 12 17 0.0008 0.057 13.8 0.8 2 23 682 703 681 703 0.96 13 17 0.00011 0.008 16.5 5.7 1 23 708 730 708 730 0.98 14 17 0.0021 0.15 12.5 5.7 1 23 760 783 760 783 0.96 15 17 0.00013 0.0091 16.3 3.7 2 21 870 889 870 891 0.94 16 17 0.00058 0.04 14.3 4.2 1 23 897 919 897 919 0.98 17 17 0.0054 0.38 11.2 2.5 1 23 924 947 924 947 0.95
Sequence Information
- Coding Sequence
- ATGGAGAATGTGTGTCGCGTTTGTAGGGATGGCTCAGTCACCTTAGTAGAAATATTTACCGCAGCGCAGAACGGTGACAATGACGATGAGGACCAAGAGAAGAACTTAGCCTTTGTTCTTAGCCAGTGTGCCAACTGTCCAGTTACGCGGGACGATTTATTACCGAAACAAATATGCTTGTCCTGTGTATTAGCAGCTCAAAATGCATTCCGCTTCAAGAAAACATGCGAGCAAAGTTATCAACACTTTTGCCAACTTCTGGAGATGGGGAGGCAGAAGCAATGCAGAGTCCCGCCGGCCCAGCAGCGATTTAACGACAATGACGTCCTCATGGATGGCGGTCTTCATGTCATCGATGAAAGCTGCATCAAAGTGGAGCCCTTTGTCGAGCCCCAGGAAAATATCATACCAATTAATAACGTTACTACGGAGGATGCGTCCATAACAGTTCCTTGTAGTGAAGATCAGGACAATAGAAATACGGAGGTGTTTCCCCATGTGTGCCAGTACTGTACTAAAGGCTTTCGTGGATCATATGAGCTAAACAATCACATTCGCAGTCGTCATACAGGCGAACGGCCTTTTAAATGTCCCTATTGTCCAAAAGACTTTTCTGTGCGCATATATTTAAGGAATCATCTTCGCATCCATACAGGAGAGCGTCCTTACAAATGCCCACATTGCCCTAACGCATTCACCCTGTCCAACAGCTTAAGAGCTCACATTCGAAAACATGGTGATGGTCGGAACAGATTCTATTCCCGTAAACTGTTTCGTTGCGATTGTTGCGCAGCATCTTTCCGGGAGCACTTTGGTCTCCGCATGCATAAACAATTAAAACATCGCAGCAATGATACATCGGCTAAAACAATTGGGAAAACTAGTGAAAAGCGGACTCAGTCGTTAGTCCAACGTTCTAAAACAAACTCCAATTTACAAAGGTTGGGAATTCAGGAAAATCCTGTGGAAATTAAAAAAGAATCGGTTGAAGAGGAAGTAGAAATCACCGCCAAATCAAATCAGAAAAATAGTGATGATTGTGAATATTGCTGTTCAATTTGTGAAATGAAATTTCGATACAAATACGGATTAATGAATCATCTGCGCTACTGTACGAAACCACCATTTGGGTGTCCAGATCCGTCTTGCTCACAGGCCTTTCAAACGGAAGTCAATCTCACACAGCATCAGAAGCGTGTTCATGCCTCCGATTGGCCATTTCCATGCAGGGAGTGTCCTAAGGGTTTCTACACCAATTACAAGCTAAAACTTCACATGCGTTCGCACACTGGAGAACGTCCATTTGAATGTCCACATTGTCTACAAAGATTTACACAAAAGCAGAACTTAAATCGTCATGTGACTAGAAGACACTCACAGGCCTCTGGTGTAGAAACAATTTCAACAGATGGACAAACCAAGTTTAGCCAAGAGACGCCCAATATAAAGCAAATTCTACCAGATCGAGATTATGCCATTCAAGAGCAAGCTATGTGCCACGTTTGCGGAAAGCATTTCTCAGACACATTTACACTAAAGCGTCATGTTTGTGGTCATACCGGTTTTAAGTGTCCTCACTGTCCAAAGTCTTACACCCAGAATAAAAATTTAAGGGCTCACATCCAGTGTCACCATAATCAATTGAGTGACTTAAATGGACCAGCGAATTCAAGAAAGCAACAGCATAAGCAGAGAAAAATTGCAAAGTCTAAAAAAGCGAAAGGAAAGAAAATCAAAAAGATAAGTTATCGCTGTAAATGGTGTCCGATTGCTTTTCGAGAACACTATAAAATGGTGCTCCATATGCAGCAGAAACATAAAAAACGTCTAAATCAGACCTCCTATGAAGAAGAACAGGATAAAGCGGTTTGTTCTAAAGAACCAATTGAAAGTGGGTTAAGTAACATAGCCACAGCGGCAACTGAAAAAGAAATCTCAATACCAAAAGATTCACTAAAGGATCATAGGTGCTGTGTATGTGGCAAGGCTTTTACGAAAAGATTGAGTTTTATCCACCATATCCGTACACATAAACCACCACTAAACTGTACACTGTGTCCAAAACAGTTTAGTTTATATGCCCAGTTAAGAGTTCACAAGCGCCAGCACACAGCCGGAAGGTTCCAATGTGCTCACTGTTCCAATTCCTATTCTCGAAAAGATAATTTAGTAAAACATATGCATAAACATAAAAAGGAAGGGATATTCGAAGCAAGATCAGAAATCAATGACACAGATCCACTTGAAGATGAGAATAGTGGACAGACGGATCCCCTTTTTAACTGTCAATTGTGCTGCAAATCATTTCGTTATAAATATAACCTAAGGCTGCATATGCTCATGAAACACGGCATTAACCAGCAAACAAATGACGTAGAAAATCAAAAGATAGATTTAAGTTTGGATCAAGAAACAAATTTAAAACTCCGCAATAGACCTGGAGCTGGTGCGTATGAAGAGCTGGAGTTCGAGGACAGTGATAATGAAAGGAGTGACATCAATAAACAGAAGGTCATATCAAGTCCAAAGGCAATCATTGGTGATGGAGTGTTATTACCACAATCACTAATAACTGAAGATCATTTGCCCAATGCGGTAAAAAGTAATGTTTGTCCGTATTGCTTTAAGTGTTACGTACGGAAAGAGAACCTAATTATTCATATGAGATGTCATACTGGAGAACGGCCATTTAAATGTTCTTATTGCGATTTAACCTTCAGTTCAAATACTGCTTGCAAAAGACATCTACGGGGACATACTGGAGATCTTTTTCGTTGCGATCAATGTCCAAAAGTGTATATGACTCGATCTGATTTACGATTTCATAAAAACAAGAAACATAGCATCTCCAACGAGGAGCCAATAGTATTAACAAAAAGGTTAATTGTACGTTTGGAACGCATTAAATTACCAGATAGTGTTAAGATAGAACCGATAGATACTTTAGCATAA
- Protein Sequence
- MENVCRVCRDGSVTLVEIFTAAQNGDNDDEDQEKNLAFVLSQCANCPVTRDDLLPKQICLSCVLAAQNAFRFKKTCEQSYQHFCQLLEMGRQKQCRVPPAQQRFNDNDVLMDGGLHVIDESCIKVEPFVEPQENIIPINNVTTEDASITVPCSEDQDNRNTEVFPHVCQYCTKGFRGSYELNNHIRSRHTGERPFKCPYCPKDFSVRIYLRNHLRIHTGERPYKCPHCPNAFTLSNSLRAHIRKHGDGRNRFYSRKLFRCDCCAASFREHFGLRMHKQLKHRSNDTSAKTIGKTSEKRTQSLVQRSKTNSNLQRLGIQENPVEIKKESVEEEVEITAKSNQKNSDDCEYCCSICEMKFRYKYGLMNHLRYCTKPPFGCPDPSCSQAFQTEVNLTQHQKRVHASDWPFPCRECPKGFYTNYKLKLHMRSHTGERPFECPHCLQRFTQKQNLNRHVTRRHSQASGVETISTDGQTKFSQETPNIKQILPDRDYAIQEQAMCHVCGKHFSDTFTLKRHVCGHTGFKCPHCPKSYTQNKNLRAHIQCHHNQLSDLNGPANSRKQQHKQRKIAKSKKAKGKKIKKISYRCKWCPIAFREHYKMVLHMQQKHKKRLNQTSYEEEQDKAVCSKEPIESGLSNIATAATEKEISIPKDSLKDHRCCVCGKAFTKRLSFIHHIRTHKPPLNCTLCPKQFSLYAQLRVHKRQHTAGRFQCAHCSNSYSRKDNLVKHMHKHKKEGIFEARSEINDTDPLEDENSGQTDPLFNCQLCCKSFRYKYNLRLHMLMKHGINQQTNDVENQKIDLSLDQETNLKLRNRPGAGAYEELEFEDSDNERSDINKQKVISSPKAIIGDGVLLPQSLITEDHLPNAVKSNVCPYCFKCYVRKENLIIHMRCHTGERPFKCSYCDLTFSSNTACKRHLRGHTGDLFRCDQCPKVYMTRSDLRFHKNKKHSISNEEPIVLTKRLIVRLERIKLPDSVKIEPIDTLA
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -