Basic Information

Insect: Drosophila stalkeri
Gene Symbol: ham
Assembly: GCA_035047405.1
Location: JAWNPR010000039.1:11748447-11773904[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.58 42 4.9 0.0 2 21 373 392 372 395 0.87

2 9 0.038 2.8 8.7 2.3 1 23 402 425 402 425 0.91

3 9 1.8e-07 1.3e-05 25.4 1.7 1 23 431 454 431 454 0.96

4 9 1.1e-06 8.3e-05 22.9 1.6 1 23 460 482 460 482 0.97

5 9 8.8e-05 0.0064 17.0 3.8 1 23 488 510 488 510 0.97

6 9 0.0057 0.41 11.3 2.0 2 21 518 537 517 538 0.94

7 9 6.8e-09 5e-07 29.9 1.3 1 23 1035 1057 1035 1057 0.99

8 9 3.6e-07 2.6e-05 24.5 0.9 1 23 1063 1086 1063 1086 0.97

9 9 4.6e-05 0.0034 17.8 6.8 1 23 1092 1114 1092 1114 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.58	42	4.9	0.0	2	21	373	392	372	395	0.87
2	9	0.038	2.8	8.7	2.3	1	23	402	425	402	425	0.91
3	9	1.8e-07	1.3e-05	25.4	1.7	1	23	431	454	431	454	0.96
4	9	1.1e-06	8.3e-05	22.9	1.6	1	23	460	482	460	482	0.97
5	9	8.8e-05	0.0064	17.0	3.8	1	23	488	510	488	510	0.97
6	9	0.0057	0.41	11.3	2.0	2	21	518	537	517	538	0.94
7	9	6.8e-09	5e-07	29.9	1.3	1	23	1035	1057	1035	1057	0.99
8	9	3.6e-07	2.6e-05	24.5	0.9	1	23	1063	1086	1063	1086	0.97
9	9	4.6e-05	0.0034	17.8	6.8	1	23	1092	1114	1092	1114	0.98

Sequence Information

Coding Sequence: ATGTTATACGAACGTTATATTATGCCAGGCTCTAACGGCGACGACTACGATCCGAGCGTCGTGcgccaccatcatcatcatcaccatcatttGGATCTCAGCAGTGGAGCGCCGGCATTTGGTCCGCTGCCTCCGGCGCACTTAACCTCCAGCCAAACTCGGCCCGAGGAGACGTTCGGTCGCCATCTGCCGCCAACGATATCCCCGCCACCTGCTGCACTGCTTCAGcagcaatcgcaatcgcaatcgcagtcgcagtcacagcagCACTCACCGTTGCCACCGCCATCGCATTTATCATTGCatttgcagcaacagcgattGCAACGTTCGCCGCCCGCCTCCGTTTCCGCCGCGATCTCTGGCTCCGGCTCCGGCCCCGGCTCCGGCTCTGTTTCCGGCAGCGGCACCAATATGGAGCATCTGTTCGGCGACAAGACGCAGGAGTTTCTACTGCAAATGGCGCGACTGCGCGACCCCTTTTGTGATCTGGACATTCGTGATACGGGCGTCTATGCCAAGACCGATTTGCCACGCGACTCCCGCTACGGTCCCTTTCCCATGCACCTGTGCCAGCAACACAGCGATCGCCATCTGGCCTGGGAGgTAATTGCCGGACCGCTATTCCATGGCTGGCTGGAGCCCTCAGCAGATGTGGCCACATGGTTGAAAAAGATACGCAACGCACAGCCCGACGAGGCTGAAGAGGCTAATTTAAGGAGTTTCATTGTCGATCGTTGTCTGTGGTACGAGACGAAACGTGATATTAGTGCAGGCGCCGAAATTGTGGTCGACGCCCGTTCCCGCACGCCCTACGACATCAGCGACAGTCTAAGGAATGgctgcagcagtagcagcggcagcagcagcgcagcagccgtggctgccacagcagcagcagccgccgccgccgctgccgctgcagccgcCATGGCAGCggctagcaacaacaacaacaacaataataataataataacaataacaatagcgaTGATCGCAGCGATCGTGATAATGGCTTTTACAGCGGCGACGAATTTGCCAAGGATAAGAAAAACATATCGATAATCAGTCAGGGCGATAACGATTTCACAGACGACGAGAACGGTTTCGATATACGCTGTGAGGTCTGTGATAATGTCTATACGGATTTAGAACGCCTAGACGATCATCTGGTGGGCGCGCATCATTTCAAGCGTGGAGAATTTGCCTGTGAGCTCTGCTCTCAACATTTCTGCCATCGTCCCTTGCTGATCAAACACGGAGCGATCGCTCATAATAATATCAGGAAATATTCTTGCGAGAACTGTTCCAAGGTATTCTGTGACCCATCGAATTTACAGCGTCATATTCGCGCCTATCACGTCGGCGCTCGCAGTCATCCGTGCCCGGAGTGCGGTAAAACATTTGGCACATCGTCGGGGCTAAAGCAGCACCAGCACATTCACTCCTCCGTGAAGCCATTCGCCTGCGAGGTGTGCTTCAAGGCGTATACGCAGTTCTCTAACCTGTGCCGGCACAAGCGCATGCACGCCGATTGTCGCATGCAGATCAAGTGCCAGAAGTGCAAAACGAGCTTCAGCACGGTCACCTCGCTATCGAAGCATAAGAAGTTCTGCGATAGCTCCGATAGCTTTCGCAGCAGCCAACAGAGTCGCCTGCAAcaccatcagcatcagcatcagcaacagcatcagcatcagcagcacgtgccgcatcagcagcagtcgcagtcggGGCCACTTCTATTGCCACCTGGTGCGCATCAGCGActcgctgccgccgccgccgctgccgcagccagcagcaacagcagcgagacAGCTGCCATGGCAACGCCACCGAATCACATGTTCACGATGCATCCCTCGCACTCCTTCTTTCCGGGCTTTCCGCCGTACACGTTGCCCAACTTCTTTACGAACTGTCggccgcagccgctgctgccgcacaTGTTTCCCAATCCACATCTGGGCGACATGGGCCGCGGCCTAGTGGCGCCGCTAGTCTCACCGAATGCTGccttccagcagcagctgcaggcagCCATGAGTCTGAAGTCAGAGTCGCCGCGCCTGAAACGCGAGTCCAGCACGCCGGAGCGCAAGCCCGTCAAGACCGAGATGCAGCGCAGCGACGACGatgaggaagaggaggaggaggaggaggacgtGTCCAATAGCTATGatcagctgcaattgcagctggaTTCGAGTAAGAAGTCGAACAAGCTGAAGTCGGAGTCAAAGCCGGAAGCTAGCGGCACGCAGCCAGCACAGCATGAGGAACAGCATCAtgccaatgataatgataatgacaacgatattgacaatgataatgacaatgatattGACAATGATAGGAAATCCATTGATATATTGAGCACACCACCGCCCGCTGAAACGGAGCTGCAGCCGGAGCCGGAGGACAAGAGCAGCGTTGATCTGCTGCCTCTGGATCTGTCCATCAGTCGCAAGCGTCGCAGCTCACTGTGCACGGCCAGCACACCCGTGCCGCTGGCCATTTCGCTGTCCAGTCGCACATCCACGCCCGCCCTGGACATATCTGAGGGCGTGGCCGGCCAGCCGCCCGTTAAGCTGATGAAGCACAGCTCCGGCGAATCGTCCACCTCGCATCAGTCCTTCAAGGGCAGCAGTCCCACGCCCAGTGTCAGCGCCTCGCCAGGACCCACGCCCTCGCCCTCGCCGCCCATTAGCACCGGCGGCGAGCTGAGCAGCATGTCCGAGAGTGcggcgtctgctgctgctgtgggcgCTGCctcggcagcggcagctgctgcctcgGTGATGGCCTGCCCACGGCAACTGCatccgcagctgctgctcgaggAGTTCTATCGCTCACGCTTCAATACGCCATCGTTTCATTTTTTAGGCCAAATGGGCGGACGGCCAGGTTTTGAGCCACTCAAATCGCCGGCTGCTGTcatcagcagcggcagcagctcgcGTCATCTGCCGTTTCCGCCCGAGCACAATTTCCATGAGGCTCTCAGAGCCGCCGGCCtggccgccgccgctgccaatGCCTGCAGCAGCGGCGCCAGCATCGCCAACGCCAACGGTGTCAAGCTCAAGGATCGCTACACGTGCAAGTTCTGCGGCAAAGTGTTTCCGCGCTCCGCCAATCTCACCCGGCACCTGCGCACCCACACCGGCGAGCAGCCGTACACGTGCAAGTACTGTGATCGCGCCTTCAGCATCTCCTCGAATCTGCAGCGACATGTGCGCAACATTCACAACAAGGAGCGTCCGTTCCGGTGTCACATGTGCGATCGCTGCTTTGGCCAGCAAACGAATCTCGATCGCCATCTGAAGAAACACGAAGCGGATGCGGGCGGCTTCGACTACAACGATTCGCCCAGTTCGAATGAGGCGAACGATCGGGAGGAGGCCTGCTTCGATGACATACGCTCCTTTATGAAGCGCGTCTATACGCCCACGAGTCTGGGCGGCGCTGATGGGGATACCGAGGAGTATGCGGGCAGCGATGATCAGTTGTCCGTCTCGACGCGTCACTCTGTCAACTTTGACAAGGAGTTGATCtccaatggcaacaacaacaacaccaacaacaacaacaacaacaacaataacaacaacagcagcagcaacagcaacagcaacaacaacaacaacaacaatcagacaGGTCTGAGTGAAACGATCGCCGTCAGCActtag
Protein Sequence: MLYERYIMPGSNGDDYDPSVVRHHHHHHHHLDLSSGAPAFGPLPPAHLTSSQTRPEETFGRHLPPTISPPPAALLQQQSQSQSQSQSQQHSPLPPPSHLSLHLQQQRLQRSPPASVSAAISGSGSGPGSGSVSGSGTNMEHLFGDKTQEFLLQMARLRDPFCDLDIRDTGVYAKTDLPRDSRYGPFPMHLCQQHSDRHLAWEVIAGPLFHGWLEPSADVATWLKKIRNAQPDEAEEANLRSFIVDRCLWYETKRDISAGAEIVVDARSRTPYDISDSLRNGCSSSSGSSSAAAVAATAAAAAAAAAAAAAMAAASNNNNNNNNNNNNNNSDDRSDRDNGFYSGDEFAKDKKNISIISQGDNDFTDDENGFDIRCEVCDNVYTDLERLDDHLVGAHHFKRGEFACELCSQHFCHRPLLIKHGAIAHNNIRKYSCENCSKVFCDPSNLQRHIRAYHVGARSHPCPECGKTFGTSSGLKQHQHIHSSVKPFACEVCFKAYTQFSNLCRHKRMHADCRMQIKCQKCKTSFSTVTSLSKHKKFCDSSDSFRSSQQSRLQHHQHQHQQQHQHQQHVPHQQQSQSGPLLLPPGAHQRLAAAAAAAAASSNSSETAAMATPPNHMFTMHPSHSFFPGFPPYTLPNFFTNCRPQPLLPHMFPNPHLGDMGRGLVAPLVSPNAAFQQQLQAAMSLKSESPRLKRESSTPERKPVKTEMQRSDDDEEEEEEEEDVSNSYDQLQLQLDSSKKSNKLKSESKPEASGTQPAQHEEQHHANDNDNDNDIDNDNDNDIDNDRKSIDILSTPPPAETELQPEPEDKSSVDLLPLDLSISRKRRSSLCTASTPVPLAISLSSRTSTPALDISEGVAGQPPVKLMKHSSGESSTSHQSFKGSSPTPSVSASPGPTPSPSPPISTGGELSSMSESAASAAAVGAASAAAAAASVMACPRQLHPQLLLEEFYRSRFNTPSFHFLGQMGGRPGFEPLKSPAAVISSGSSSRHLPFPPEHNFHEALRAAGLAAAAANACSSGASIANANGVKLKDRYTCKFCGKVFPRSANLTRHLRTHTGEQPYTCKYCDRAFSISSNLQRHVRNIHNKERPFRCHMCDRCFGQQTNLDRHLKKHEADAGGFDYNDSPSSNEANDREEACFDDIRSFMKRVYTPTSLGGADGDTEEYAGSDDQLSVSTRHSVNFDKELISNGNNNNTNNNNNNNNNNNSSSNSNSNNNNNNNQTGLSETIAVST

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00568407;
90% Identity: iTF_00493810;
80% Identity: -