Basic Information

Insect: Drosophila sproati
Gene Symbol: -
Assembly: GCA_018904355.1
Location: JAEIFY010000094.1:424967-426297[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 5 5.6e-06 0.00038 20.5 0.2 1 23 206 228 206 228 0.95

2 5 0.0001 0.0068 16.6 2.6 1 23 234 256 234 257 0.96

3 5 0.00014 0.0092 16.2 3.5 1 23 263 286 263 286 0.97

4 5 2.7e-05 0.0018 18.4 0.5 1 23 292 314 292 314 0.96

5 5 0.00096 0.065 13.5 3.2 1 23 321 345 321 345 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	5	5.6e-06	0.00038	20.5	0.2	1	23	206	228	206	228	0.95
2	5	0.0001	0.0068	16.6	2.6	1	23	234	256	234	257	0.96
3	5	0.00014	0.0092	16.2	3.5	1	23	263	286	263	286	0.97
4	5	2.7e-05	0.0018	18.4	0.5	1	23	292	314	292	314	0.96
5	5	0.00096	0.065	13.5	3.2	1	23	321	345	321	345	0.91

Sequence Information

Coding Sequence: ATGTCGGTTCACTGTAGAACTTGTGGAGAACCTATTTACAATCTCAACCCCAGAAATCTCTTCAGTCATGAGAACAAAGACATTCGCAAAAACATCGAAGCAATTACAGGAATAAAATTATCTTATCACTCGCATCTACCGAGCCATGTGTGTTCCTGTTGTTATTTGGACTTGAACCATTCTATGGCATTTCGGCAACGCTGTCTGGTGACACACAAGCATTTCATGAGCTTAAAACAAGCAGATTTCGCTGAGAAGAACTTAATTTCCAAGCAATCTTTGCTGGCCATCGATCTATTGTTTGATTATGATCTTAGTGCTGAAGAAGATGCGATCATTGAATCCAAGTACATGACTGACTACCCCTCAAGTACCAATGTATCATCGTCCCCTAAGAAACTTGTCCAAAATACCCCAAGCCATCTTTCGCATCGAGTACGTATTATGCGTTGTCGTCATCCAAGTGAAGCTCTCGAAAAACCAATTCGTCCGACAACAAATCCTGCGGCACCTTCAATCATTTCAAGGTCGACAAGAAAAGTAATCAGAAAGTTGCCTGATGAAATGCGAAATGTCAAGAAAAATAAGCCGCGTATTGCGCCACTGGAGAAGAAATTCGTTTGCGACCAATGCGGCTGGTCTTTCCGTGATCTGAGCAATATGAAGGATCATGCAGTGCGCCATTCGGGCGTCAAAAACTTTGAATGTGAAGAATGCGGCTGTAAATTCTTCACGCGACCTCTGCTCATGCTCCACGTGCGTGTCCACCACAAAGGCGAGAAGCCCTTCGTATGCAAATATTGCGGAATGGCCTTTCGCAACAGTCCCAGTCGGTGCCGGCACGAACGGAAATACCATGCAAAGGAATTACCCTTCGTGTGCAATCTTTGTAGCAGGACGTTTATAAGTAAAATTAGCTTGGAAAAGCACAGAGAGGCTCATGATTTGGGAGAAAAGATCTATCGCTGCGAAACGTGCAAGAAGACCTTTAAGGGAGCCATATTTTTAAAAAATCATTACACTACAAAGTTTCATCAGAGGAGAGTTAATCAAATGATTAAAGATGACTTGGAGGCAGCTGATATAACAAAGGTCAGCGATGGCGATGTTAATTTTGATTTTTCCGATTCTATTATTGAAGAAATTGAAAATTAA
Protein Sequence: MSVHCRTCGEPIYNLNPRNLFSHENKDIRKNIEAITGIKLSYHSHLPSHVCSCCYLDLNHSMAFRQRCLVTHKHFMSLKQADFAEKNLISKQSLLAIDLLFDYDLSAEEDAIIESKYMTDYPSSTNVSSSPKKLVQNTPSHLSHRVRIMRCRHPSEALEKPIRPTTNPAAPSIISRSTRKVIRKLPDEMRNVKKNKPRIAPLEKKFVCDQCGWSFRDLSNMKDHAVRHSGVKNFECEECGCKFFTRPLLMLHVRVHHKGEKPFVCKYCGMAFRNSPSRCRHERKYHAKELPFVCNLCSRTFISKISLEKHREAHDLGEKIYRCETCKKTFKGAIFLKNHYTTKFHQRRVNQMIKDDLEAADITKVSDGDVNFDFSDSIIEEIEN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00482536;
90% Identity: iTF_00564927;
80% Identity: -