Dspr014655.1
Basic Information
- Insect
- Drosophila sproati
- Gene Symbol
- -
- Assembly
- GCA_018904355.1
- Location
- JAEIFY010000104.1:3574224-3580815[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 12 0.034 2.3 8.6 0.2 1 23 1022 1045 1022 1045 0.94 2 12 3.1 2.1e+02 2.5 0.2 1 23 1215 1237 1215 1237 0.91 3 12 0.00012 0.0083 16.3 2.7 2 23 1240 1261 1240 1261 0.97 4 12 0.35 23 5.4 5.1 3 23 1269 1292 1267 1292 0.84 5 12 3.5 2.4e+02 2.3 0.4 5 23 1305 1323 1302 1323 0.95 6 12 0.93 62 4.1 5.4 3 23 1330 1351 1328 1351 0.93 7 12 0.099 6.6 7.2 0.2 2 23 1362 1382 1361 1382 0.96 8 12 3.8e-05 0.0025 17.9 0.4 1 19 1388 1406 1388 1410 0.95 9 12 1.1e-05 0.00073 19.6 0.5 1 23 1418 1440 1418 1440 0.98 10 12 7.1e-05 0.0048 17.1 7.6 1 23 1446 1468 1446 1469 0.96 11 12 0.00014 0.0093 16.2 5.9 1 23 1474 1496 1474 1496 0.98 12 12 0.02 1.3 9.4 8.2 1 23 1502 1524 1502 1525 0.95
Sequence Information
- Coding Sequence
- ATGGTGGACAGTGTGCAGTGCCCCGTGTGCACCTTGTATCTGCATGCGGGCATGAATCTCTCCGATCACTTGGAGACACATCCCAAGGAGCAGGTCATCAAGGCACTGGTGCAAATGACCATTGCTGGCAACAACAATGGTGGTCTGGACAGCGCCCTGGCGGCAGCTGCGCCAGCCACCACATCCAACAACAACACACCCACCATAAGCAACGTGTCTGCTGTCTATCCGGCAACCCTGGCAACCGAATATCGCTACGAACAGCAGCAACAGCCACAGCTACAGCAGCAGCACCAGCAGCTGCATGGCTTTCCACGCGGCACCACCACTACACTGGTGATACCACAAGCGCCGCCGCAACAGCACCACAATTTTCTGGCCAACCAACAGCCGCCTGCGCACTTTGCCCACCAGCAACAGCAGCCGCAGTCGACCATGAAGTTCACGTATGCAACAGCAGCGTTGCCTCCGCCTCCCTTGCAGCTTTTTGCACAGCAGCCGACGTCAACGCAGCCGCATCAGAAGCCTCCACCCGCCTATGGCGCCGCCATCAGTCAAATTCGATCTCAGCATAACCAAAACAAGCAACAACACCAACACCACCAACAACAGCAACAGCAACCACAACACATAAGCGTACAGCAGCATAATGCGAATGCAGCACCACCGAGTGGCAAACAACAACACAATGGCAAAATCCATGCGGATATCTTTCTGAATCCACCGCCACCGCCACAGCTCACAATTCCATCGTCGGCGTCGGCGTCATCGTTGTCGTTGTCGCTGTCCCTGTCCTCCTCGGTTGCTCTGATGTCCGGCACATCGTCGGCACGCGCCAGCAGTCGCCAGTCGAGCAATTCACCCTTTGGTGCCCTGCTGAATGCGGCTGCGCACGCTGCCTGCTCCTCGCCCGCTTCGACTGGGGCGTCTGTGCTGCGCTATGCTGAGTCGCCAGTGGCCCACTATCTGGAGCGGGATAACGGTGATTTCATAGTGCAAGAGACGCCCAAGCACATTGTGGAGTGTGTCGAGAAAGACGATGGCGAATTCTCCGTGATTGAGCGCATCTATCAGTCGCCACCCAGCGTTCTCCACATACACGACGACGACGAAGAGGAGGAGGAGGACGAGGATGATCAGCAGGGTTGGGCAAACAGCGATGAGGAAGATCACGTCAAGGTGCCACACGAGCATGTCGAGGATGGCGATGATGAGCACGAGGATAGTCGCAGCCGAGTTGCACCCAAAACGACAACGAAAAAGTCGCGCAAGACAAAATCGAGTGGCAGATTGCACAAGCGCGCCTCCAAGCATCAGCTGGCCACGACGACGGAGGACGAGGACGACTTCATGAGCATAGGCAGCAGTTCACAGTTGGCGGCGAGCTCATCGCCGGCTCAACTTTGCACTGCGCCCTCCACGAGCAGTGGAGGTGCTGTTGCTGCTGCTGCTACCGCCGCCAGTGGTGGTAAATTCATGGCCAGCGGCACCATCAAGTCCAAAAAGAATCGGGTAACGGTGCTCAGCGATGTGCCGCTCAACATGAACGAGTATCTGGATCTGGTGGGCAACATTGTCGCCTCGACTCGCATTGGTGCAGCGCGTCCCTTTGCCGCTGTAGCGCCCATACCGCTCGTCAAAGTGGAAAAGGAGGAACCCATGGATGAATATGATGCCGTTGAGGATCTCACACAGCCGCCGCCGATGAAGGTGGAGGTGGAGCCAACGGCGCTGCTGCCGCAACGCTTCTCGGCACCGGGGCAGCTGCGTGGACCCAAGAAATTAGTCATCAAACCAAAGGCCACAGCGACGGCAACGGCGACGTCAACGACGAAAAAGACTGAGAACAACGCTGCTGCTGTTGCTACTGGCAGCAACAGTAGCAATTGCGCCGAATCCCATAGCATATCAGTGAATACGCCCGCCGAGCTTGTGCAGATCAAGAGCGAGAACGTGGAGGCGTCCACATCGAGCAGTGGCAGCATATTGGAAAAGCATCTGACTAACAGCTATGCGGCACAGCAGGCGGCACGCAAGCACTCCGCCGTCAACGATGACGATGCACGTGTGCTGCTCGAGTTTGCCAACTCGAAGCAGCTGCCGATGCCGGGCAACAGCAATCATACCACGTTTGTGGTGAACGCGGCCAGTTTTGCGTCAGCGGGTTCCGTATTTGCCAGCGGCAGCAGCATCAGCGGTGTCAATGTGCAAAAGTCAACCAAGCCGGGCTGTGGCGATGAGTACATTCTGCCCGACGACACCAAGCTGGAGGAGTGCTCGATGAATGCCACGTTTCGTGTGGCAAAGCCACAATCAATGCTGGGCACCTGGTATCAGCCACATCAGGCGCAGCATCAGGTGACATCTTCGCACAGTCCACAACATGTGGATCAGCCGAGCAATTTTATTGCGGCTCTGTCTGCCGTCGACTGCTGCAGTGCAGCCGTCGACAGCGATATGAGCGAGGCTAAATACTTGGATCTGGATGCCTGCAAGCGGGAACAGCTGAGCAACAGCAGCAGCCATATGCCATCCGCTTCGACATCGACCACATCGTCATCGTTTGCTGCCGCAGCAACGGAGAGCAGTCTCGTCGGTGGCCTGGGTCTGAATATACGCACCGATGAGAAAATGCCCGCCAAGGGTGAGATTTCCGAACAGGAAAGCAACTGCGACATAGAGAACTCTTGGAGTCAATCGATGTATGGCGACATATCACAGCGTTACTTTAGGAATCAGTTCACGGATGGCTACAATCAGCAGCTGGCCGATTGGCGTCACGACTATTATCCGGCGCAGGATCTCAGTGGCCAGCAGCAGCAGCGAGAGCAAAAACGATTTGACTTCAATGCGGTCGCCTCGGAGTACGCACAGCCGGGCGAGCTGGAAGCTTCCTCGAGCTCAACGAGGAACAATCATTTGTTGGATGCACAGCCCACCACTTCCTCGTCGTCATCGGCTTTGTTGGCTGGTCCACCAATAGCCTCGACATCCCGCGCTGCCGCCGAAGCGGAGGCGGTTGCAGCAGCACTGGCTCAACGGAAGCCAGCACGTCGCAAGATCTACAAGTGTCCACATTGTGTGGCCATCTTCGAGAAGCTAAAGGAGCGCAATGCGCACATGATTGGCGAGCACAACTATGTGCGCCAGAATCGGCGTCTCATCTGCACGCAGGCGCTGGTCAGCGCTGCGATGCTCGCCCAGCCGCTGGCTCAGCAGTCAGAGCAGCAAATGGAGCTGGAACAGCAGCAACAGCATCAGTTGCTGCAGGTGAGCCACAGTACGGGCGGCGCCGAGCACGAGGATTCCAAGGATGGTATTGTGAAGATTAAGCAGGAACATTGTCACGACAAGCACGATGCAGCATCGGAGCAATTGCTTGGCCACTTGGAGCTGCCGGATGTGAAGGATGCTGGCCTGCTCGAAACCAGTGGTGAAAACGGACGCGATGCGGACATGAAGCCACCAACCACTGTTGCTGAGCTTGACGAGAAACCGACCATAGCACCGCTGGCCATGACGACGCCCGCTGCCAAACTGGCTGCTCTTTATCGCATGCTAATTGCCTACAACGAATCGAAGCTGGGCCAGGAGCGCAACAATCTAAGTGAACTGGAGCAAAAGGCCATGGAGAAATCTATATTCTTGTGCTACATTTGCCGAACCGACTTCCCCTCTGTGAAGCTGTACGATGCGCATCTAACCGAGCATCCCGCCGAGTGTTTCACTTGCGGCAAAAAATTCTATCGCTGGAAGAACTTCTCGCTGCATCTGAAACGCCATCTGGGCTGGAAGGAGTTTGGCTGCTATGTCTGCGACAAGAAGTTTGTGAAGTTCAAGCGATACTCGAACTTGACGCAGCATCGCAAGCGCCACACTAAGATGACGGTGCGCAAAAAGGAATATGTATGCCACTGTGGCGAAGTGCTGCCCTCAAAGGCCCGCTTCCTGTGGCACAAGGAGACGCACGACTTGAAGCCCAAATGCTGTCCGTACTGCTGCGATCGTTTCGTGCATGCGAACTCGCTGCGTCGACACATCCGGCTGGCGCATTCGGACAAGTTCGACTATGCCGAGCCGATGGAGTGTCCCATGTGCAAGCAGATCTTTGCCAAGACATCGATTAAGGCGCACATGGCGACGCACTCGACGGATCCGCAATACGATTGCGCCATCTGCAACAAGAGCTTCTCCACCAAATGGAATCTCAAGATACATTCGTGGGTGCATGCGAATCGAACGGCCAAACCGTTCAAGTGCGAGTACTGCCCGAAGGCGTTTGTGCGCGAGTTGGACTTCAAGAATCATATGAATGCGCACAAGCAGATCAAGCCGTACACCTGCGAATATTGCGGTTGCAAGTTCATACGCAAGTACAACTATATGCGGCATAGGCGGGAGCATCATGGCAACAAGAAGTTCACGTGCGATCAATGCGACAAGTCTTTCCATCGCCACTACTATCTGATTGAGCATCGGCGCATTCACACTGGCGAGCGACCCTTCCACTGCACCATCTGTGGCAAGAGCTCCACCACAAAGACCAATCACAACAAACATCTGAAGATTCATCATTCGCGCGATCCCTTCACTGTGGAGGTCTAA
- Protein Sequence
- MVDSVQCPVCTLYLHAGMNLSDHLETHPKEQVIKALVQMTIAGNNNGGLDSALAAAAPATTSNNNTPTISNVSAVYPATLATEYRYEQQQQPQLQQQHQQLHGFPRGTTTTLVIPQAPPQQHHNFLANQQPPAHFAHQQQQPQSTMKFTYATAALPPPPLQLFAQQPTSTQPHQKPPPAYGAAISQIRSQHNQNKQQHQHHQQQQQQPQHISVQQHNANAAPPSGKQQHNGKIHADIFLNPPPPPQLTIPSSASASSLSLSLSLSSSVALMSGTSSARASSRQSSNSPFGALLNAAAHAACSSPASTGASVLRYAESPVAHYLERDNGDFIVQETPKHIVECVEKDDGEFSVIERIYQSPPSVLHIHDDDEEEEEDEDDQQGWANSDEEDHVKVPHEHVEDGDDEHEDSRSRVAPKTTTKKSRKTKSSGRLHKRASKHQLATTTEDEDDFMSIGSSSQLAASSSPAQLCTAPSTSSGGAVAAAATAASGGKFMASGTIKSKKNRVTVLSDVPLNMNEYLDLVGNIVASTRIGAARPFAAVAPIPLVKVEKEEPMDEYDAVEDLTQPPPMKVEVEPTALLPQRFSAPGQLRGPKKLVIKPKATATATATSTTKKTENNAAAVATGSNSSNCAESHSISVNTPAELVQIKSENVEASTSSSGSILEKHLTNSYAAQQAARKHSAVNDDDARVLLEFANSKQLPMPGNSNHTTFVVNAASFASAGSVFASGSSISGVNVQKSTKPGCGDEYILPDDTKLEECSMNATFRVAKPQSMLGTWYQPHQAQHQVTSSHSPQHVDQPSNFIAALSAVDCCSAAVDSDMSEAKYLDLDACKREQLSNSSSHMPSASTSTTSSSFAAAATESSLVGGLGLNIRTDEKMPAKGEISEQESNCDIENSWSQSMYGDISQRYFRNQFTDGYNQQLADWRHDYYPAQDLSGQQQQREQKRFDFNAVASEYAQPGELEASSSSTRNNHLLDAQPTTSSSSSALLAGPPIASTSRAAAEAEAVAAALAQRKPARRKIYKCPHCVAIFEKLKERNAHMIGEHNYVRQNRRLICTQALVSAAMLAQPLAQQSEQQMELEQQQQHQLLQVSHSTGGAEHEDSKDGIVKIKQEHCHDKHDAASEQLLGHLELPDVKDAGLLETSGENGRDADMKPPTTVAELDEKPTIAPLAMTTPAAKLAALYRMLIAYNESKLGQERNNLSELEQKAMEKSIFLCYICRTDFPSVKLYDAHLTEHPAECFTCGKKFYRWKNFSLHLKRHLGWKEFGCYVCDKKFVKFKRYSNLTQHRKRHTKMTVRKKEYVCHCGEVLPSKARFLWHKETHDLKPKCCPYCCDRFVHANSLRRHIRLAHSDKFDYAEPMECPMCKQIFAKTSIKAHMATHSTDPQYDCAICNKSFSTKWNLKIHSWVHANRTAKPFKCEYCPKAFVRELDFKNHMNAHKQIKPYTCEYCGCKFIRKYNYMRHRREHHGNKKFTCDQCDKSFHRHYYLIEHRRIHTGERPFHCTICGKSSTTKTNHNKHLKIHHSRDPFTVEV
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00514348;
- 90% Identity
- -
- 80% Identity
- -