Basic Information

Insect: Drosophila sproati
Gene Symbol: GFI1
Assembly: GCA_018904355.1
Location: JAEIFY010000122.1:3939975-3959705[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 0.00017 0.012 15.8 3.6 1 23 522 545 522 546 0.96

2 6 0.00026 0.018 15.3 0.5 1 23 551 573 551 573 0.97

3 6 3e-07 2e-05 24.5 1.9 1 23 579 601 579 601 0.98

4 6 1.5e-05 0.001 19.2 4.2 1 23 607 629 607 629 0.97

5 6 1.8e-07 1.2e-05 25.2 2.5 1 23 635 657 635 657 0.98

6 6 3.7e-05 0.0025 17.9 5.0 1 23 663 686 663 686 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	0.00017	0.012	15.8	3.6	1	23	522	545	522	546	0.96
2	6	0.00026	0.018	15.3	0.5	1	23	551	573	551	573	0.97
3	6	3e-07	2e-05	24.5	1.9	1	23	579	601	579	601	0.98
4	6	1.5e-05	0.001	19.2	4.2	1	23	607	629	607	629	0.97
5	6	1.8e-07	1.2e-05	25.2	2.5	1	23	635	657	635	657	0.98
6	6	3.7e-05	0.0025	17.9	5.0	1	23	663	686	663	686	0.97

Sequence Information

Coding Sequence: ATGAACGTTGTCAAGATGCAAGCGCCTGGCCAGCACCAGCATCCGCATCATTTGCTGCATTCGGCTGCATCCGCTGCGCCGCCACCGACGCAACAACATCATCTGCCCATCGATTATAGTTTGGGCAACTTTAAGCCCGCCATTGCTGCCGATTTTCCTGGCGGCCCCTTTGTCGCCAGCCCCCAGCAGCAGCAGTCATCCTCAGCCTCCTCCACGTCGCCGCCCTCGATTGTCACGTCAAGCGCTTCGCTGCAGGTGCGAGATCTCAGCGCGTTGACCACAATGGCAGCGATACCCTCGCCCACACAGCTGCTCCATCAGCGCATGCAACAGGCCCAAATCACTGTGGATGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNAATGCCGCCGGCGGCAACATCGCCCCACGATTACGCGCCCATGTCCGCCTTCAAGGCGGTGCTACCCAAAAAGCGAACTTCCGACGATGCGTCGCACCCCTTTAGCATAAGCAGATTGGTCAAGACTGAACACCTGACGGCAATTGTGGCCGCTGCTGGCCTTAAGCCGCCGCCGCCTCTGCCTCTGCCGGCGCACAGCGTCGCCTTGGCGGAGGACAACAACAACTCCATCTCGATGCTGAGCAAGAACCAACAGCAACAGCACGAACCACACAATATTCAGCGTCCCAAGCTGTTGCCTTATTTAAGCGCCAGCGAGCAACTTCGTCAATCGCGCTCCCGATCGAGATCGCGTTCGCGCAGCGCCTCCCACTGCTCCTCGCAGATCGACATGGACGATGCGGATAGCAGTCATGAGCGATACTCACGGCATTCGCAACGCTCGCTGCATTCGAGATCCCGTTCCCGCTCCAGATCACGATCGCACTCGAGCAGCTCCTCTGTGGAGCTGGAGGTGGACTCGCCACCAGGTAGTCCCAGCATCAGTTCACCCAGTGCCGCCTCTGTTTCCGCATCCGAGCTACTTATCACGGCCAACAGCAACATCAGCGCCAAGAAATCGGATCTCTTCTCCGTCTCCGCGCTCCTGCGTCGCGATGAACCCACAACACGTCGCGTCCGTAGTCCACCGCTTGGCCTCGCCGGCGCCTCGACTGCTGCGCTGTCAGCGCTGCCCACCAATCCGCTGGAAGTCATGCGCCAGAGCTACCCGCCCAACTACGATGCTGCCATGTTTCAGCGCCCCATCTTCTCACCAGCGCTGCCCTTCTTTGCCGCCATTGCCTTCCACCAGGGTCAGCAGCAGCAACAGCAACAGCAATCCGGACTAGTCACTAGTTACCATCCGGACTCACAGGAAAATCTCTTCCGGCTGCGCAGCCTAATGGTGCCACTGCAATCTGCTGGCCAGAATGGCTCCACAGCGGCAGCGGCGGCGGCGGCGGCGGCAGCAGCAGCGGCTGTTGGTGTGGGCGTGCCACCCGGTGGCGGACATTTGGGTCTGCCACATCCGCCGCATCTGCACTTTCATCACATGGCGGCCAAGTGGCCGGGCCTGCATCAATTTAGCGACCTGTACTCGTGCATGAAGTGCGAGAAAATGTTCTCCACGCCCCATGGACTCGAGGTGCACTCGCGCCGCACCCACCACGGCAAGAAGCCCTACGCCTGTGAGCTATGCAACAAGACCTTCGGCCACGAGGTCAGCCTCAGCCAGCACAGGGCGGTGCACAATGTGGAAAAGGTCTTTGAGTGCAAACAGTGCGGCAAACGCTTCAAGCGCTCCAGCACCCTCTCCACCCATCTGCTCATCCACAGCGACACGAGGCCTTATCCCTGCAGCTACTGCGGCAAGCGATTCCATCAAAAGAGTGATATGAAGAAGCACACCTACATTCACACCGGTGAGAAACCGCACAAGTGCCAGGTGTGTGGAAAGGCTTTTAGCCAGAGCTCCAACCTGATAACGCATTCACGCAAGCATACCGGCTACAAGCCATTCTCCTGCAAGCTGTGCCACAAGTCCTTCCAGCGCAAGGTGGATCTACGACGTCACAAGGAGACACAGCACACAGATCTGCGCGTCCATCTCGGCAAGGTGGACTTCATGTCTGCCGCAGCGGCAGCCGCAGCCGTTGCCGAACTGAATGGAGCTCCGGGTGCTGGCATGAGTATGTCAGCTGGTGGTGCAGCACCACAAACCGGTACAGGAGCGCCAGTCAGTGCCACCACGCCGGTCAACTCGATGAATTGCCAAAAGGTATCACTGCTGGCATAA
Protein Sequence: MNVVKMQAPGQHQHPHHLLHSAASAAPPPTQQHHLPIDYSLGNFKPAIAADFPGGPFVASPQQQQSSSASSTSPPSIVTSSASLQVRDLSALTTMAAIPSPTQLLHQRMQQAQITVDXXXXXXXXXXXXXXXXXXXXXXXXXXMPPAATSPHDYAPMSAFKAVLPKKRTSDDASHPFSISRLVKTEHLTAIVAAAGLKPPPPLPLPAHSVALAEDNNNSISMLSKNQQQQHEPHNIQRPKLLPYLSASEQLRQSRSRSRSRSRSASHCSSQIDMDDADSSHERYSRHSQRSLHSRSRSRSRSRSHSSSSSVELEVDSPPGSPSISSPSAASVSASELLITANSNISAKKSDLFSVSALLRRDEPTTRRVRSPPLGLAGASTAALSALPTNPLEVMRQSYPPNYDAAMFQRPIFSPALPFFAAIAFHQGQQQQQQQQSGLVTSYHPDSQENLFRLRSLMVPLQSAGQNGSTAAAAAAAAAAAAAVGVGVPPGGGHLGLPHPPHLHFHHMAAKWPGLHQFSDLYSCMKCEKMFSTPHGLEVHSRRTHHGKKPYACELCNKTFGHEVSLSQHRAVHNVEKVFECKQCGKRFKRSSTLSTHLLIHSDTRPYPCSYCGKRFHQKSDMKKHTYIHTGEKPHKCQVCGKAFSQSSNLITHSRKHTGYKPFSCKLCHKSFQRKVDLRRHKETQHTDLRVHLGKVDFMSAAAAAAAVAELNGAPGAGMSMSAGGAAPQTGTGAPVSATTPVNSMNCQKVSLLA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00586160;
90% Identity: iTF_01322121;
80% Identity: -