Basic Information

Insect: Drosophila sordidula
Gene Symbol: zfy1
Assembly: GCA_035047465.1
Location: JAWNPQ010000163.1:6384702-6398387[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 5.3 3.4e+02 1.9 0.2 1 20 637 656 637 660 0.76

2 6 0.33 22 5.7 1.9 1 20 666 685 666 687 0.93

3 6 7.3e-05 0.0047 17.2 2.0 2 23 699 721 699 721 0.96

4 6 0.068 4.4 7.9 0.4 1 23 731 754 731 754 0.94

5 6 3.3e-05 0.0021 18.3 1.0 2 23 762 783 761 783 0.97

6 6 0.35 23 5.6 2.0 1 23 789 814 789 814 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	5.3	3.4e+02	1.9	0.2	1	20	637	656	637	660	0.76
2	6	0.33	22	5.7	1.9	1	20	666	685	666	687	0.93
3	6	7.3e-05	0.0047	17.2	2.0	2	23	699	721	699	721	0.96
4	6	0.068	4.4	7.9	0.4	1	23	731	754	731	754	0.94
5	6	3.3e-05	0.0021	18.3	1.0	2	23	762	783	761	783	0.97
6	6	0.35	23	5.6	2.0	1	23	789	814	789	814	0.94

Sequence Information

Coding Sequence: ATGAAGCGACCAACTGACGTCCGCACTCAATGCCAGATGCAaagCCTGCCGCCTCCGTCGCCGGCGCACACGCCCACCAAGGGCTTCGATGGCAACTTCAAGCTGGAACCGAACCTGAGCGTCAAGGACTTTGCGCCACCGCCGGagaatggcaatggcaacggcaatggcaGCCTGGAGTCCAGCGGCGTGACCGCTTcgatggccacgcccaccccgccGCAGCGCAAGCGCTACAAGAAGCGGGTGCAGTTCACCACCGACGCCCTCAACGGCTTTGCGGGCGCCAAGGGCAAGGGTGGCGCTGCGATGGCAGCTGttggcgccgccggcgccagcgccagcgccgccgccggctacgcgaacaacagcaacagtttcGCCAGCACGCCCAAGTCGAAGAAGCAGGAGGCGaaagcggccgccgccgccctaAAGGCGggcgctgcggcagcggcagcggcggcggctgcggcggccgcCTCCTCGGCCCTGCCCGAGGTGCTCGACTGCCGCATCGCGGAGAAGATCAAGAGCGAGCTGGAGGCCAGCAGCAAGGAGTCGCTGCCGAGCGCGCTGTGCCTCAAGAAGGCGgcggcagccgctgcagcagccgcagcggcggcgcgCCACAGCGACGAGGAtgaggacgacgaggaggatCATCAGCACCATCAGCACCACCATCGCCATCAccatcaccagcagcaacagcagcagcagcagcagcagcagctgtcgctgTCAACGTCGGCAGCGGGCAATGTCCATTCCTCGGCGGCGACCGCGGCGTTGGCGGCCTCGGATGCGGTGgacgccagcagcgccagcaacggCCAGCTGGGCGGCTTTCATGTGCGCTCCAAGGGCCAGGCCAGCAGCAAGAAGTCGCAGTcggcaaaagcagcagccgccgcagcagcagcggcggcggcagcggcggcggcagcagcggcggccatGATGCCGCCGAATAGCTACGATGAGCCGGAGGATGATTCAGCGGCTGGGCCgggcgacgacgatgacgaggaCGATGAGGAGCTGGACGAGGAGGCGCTGGCGCGTGAGATGAAAATGGAGCAGAACTTcgtggaggaggaggatgagCACGACATCGCCTTCCGGTCGCAGCAATCCTGCCGCGAGTGCTCCATCTCGCACGACCACAAGCTGTGCCCGCTGCGGAACGCGTGCGGCAATGTGACGGACGCCGTCGACCTGGCCGAGTGGATCGAGCGGCGCAACCTGGAGGCGCTGGCCAAGCTCAAGGCTGATGCACAGCGCCAGGCGAAGGTGGGCCGGCCGCGTCACgatgacgacgaggacgacatggaggacatggacatggacgaATCATCGCAGCTGTCCGAGCTGGAAACGAAGCCGCTGATCACCTTCGCCGAGGCCTCCGTGCCCGCCGAATTCGAGCTGCACAACGTCGAGCCGAACGTCACCGGCGTCTTTGCCCGGACCGAGGTGCGCGCCTACACCAAGCTGGGCCCGCTCATCGGGCAGCCGGTGCAGACCGGCGAGGTGCGCGAGGGCAGCGACATGAAGTGGATATTCGAGATGTGCGAGGCCGGCGCCGACAAGTCCTATCTGCTCTGCTGCGACAACCCGAATGCCTCCAACTGGCTGCGCTTCATCCGGCCCGCGCCCAGCTACGAGGATCGCAACGTCAACCTCGTCTCCATCGATCGTCAGGCCTACTTCGTTAGCTGTCGCGATCTGCGCAACGGCATGGAGCTGCTCTACTGGAGCGACGACTGCAACACCATGTGGCGCAAGAAGCACACCGAGAAGACAAactgCGGCGGCTGCAATTTGAAGTTCGAGCATCCGCTTTACTATCGCACGCACTGCTCAGTTTTTCATGATCCATCGATGAGCCTCACCATACGGAAATATCACTGCAAGGTGTGCGGCGAGGCGGTGCTGGGCAAGGACAACATCATGAAGCATGCGGCCGAGAAGCACGACGGCAAGGGCGCCTATCAGTGCCAGTTCTGCAACAAGTTCTTCCTGCGCCTCAACTATCTGGAAATGCATCGCACCTACGGCTGTGCCTCGAACCCGAATCGGTCGCGGCCCGTTTGCGATTTCTGTGGCCGCAAATTCTGTCAGCCGCAGAAGCTGAAGGCGCACATTAAGCGCGTGCACAGTGaTATGGCTGAAGTTTTACGAGATTTTCAGTGTAAATTATGTTCAAAACTTCTAGGATCGCGTGCGGCACTGCAGCGCCACTCGAAGGAGGTGCACAGCCGCAACTCGACCGTGGTCAGTTGTCCGCGCTGCCAGAAACTCTTCCAGAACCGCAGCAATCTGAAGATCCATATGCTCACGCACTCGGGCGTGCGGCCCTTCAAGTGCGCGGAACCGGAGTGCAACGCCGCCTTCACCACGAAGCAGTGCCTGCAGTTCCACTACAAGAAGGTGCACAACTACACCCAGGAGCAGATGCCGAAGATCGAGCGCAGCGTGGCGTACACCTTCGATGCGTATTCGGGCGGCATGAAGGTGGACTTTTTGGAGCAAGCACCGCGTCGGCGGCGCAAGAGCCTCGAGGATCAGAACCAGAACTCCATGCTCAGCAGCTCGATGCAGAGCGACACCGAGTACAGCGACGACAACATCTTCGAGGCGATCAAGAAGAGCGGCAAGTCGATCAAGGATCTGTGCCGCAACGAGCCGAACCTCTCGCTGCTCAGCTCCAAGATCTCCAGCATCTTTGGCGACAAGGTGCCGGCCGTGCAACAGGCCCCCATTCCGCCCAACGCCGGCGGCTCCTCCGTTGCGGCTGGCGCCGGACGCAAGCGCAAGCGGAAAAAGGAGCCGGCCACCTCGCTggccgcacagcagcagcaacagcagcagcagcagcagcagcagcagcagcagcagcaacaacaacagcaacagcagcagctgcagcagcaacagcagcagcagcagcaacagcaacagcagcagcacgcccAGCAatgccaccagcagcagcagcagcagctccacggCCATCTGgagcagtcgccgtcgcatcTGTCGCAcgcgcatcagcagcagcagcagccgcagtaccacagccacgcccactcgcacGGACATGCACACGCCcacccgcagcagcagcagcaacagcagcagcagcaacagcagcaacagcagcagctgcagcagcagcagacggccGCGcttcaccagcagcagctgcacgatgccgacgaggaggaggagagcGCGCGCCTGGAGCAGGTGCGCCGCAAGCAGAACGCCCAGCTCAGCCTGGTCGAGTCCTTCCTGACCACCACCGCGCAGCGGCTGAGCGCCCAGCAACAGGTGCAGCAGGTGGtcgccgccgcggccgccgtCTCCGCCATGGCCGGCGCTGGCGAGGATCCCGCCAAGCTCGGCCACATGATGGGGCACATgggcggcgtgggcgtgggcgtgggcctggacgatgacgatgatgacgacgaggacgatgaCGACGGCACCGctcaccaccaccaccaccagcagcagcagcagcagcaacagcagcagcagcagcaccagcaacaacaccagcagcagcagcagcaccaccactcGCACCAGTCGCATCCGCACCACGCGCACGCCCActcgcatccgcatccgcaccCGCATCCGCATCCCCACCAGCACGGACAGCAGgcggcgcagcagccgcacaGCGAGGCCGGCTATCGGCATGCGGCCGCCATGAACGCGGCTCTCGGCCAGAACCTGGTCGTCAGCAAGGGCAGCAAGAAGTGGATCGGCGCCGACGATCGCCATTTGAGCGACGGCGGCGATGTGGCCAACGATGCGGCcgttggcggtggcggcggtgggggctccggctccggcggcggcggtggtgctgGCTGCGGTCAACTGGCCGGTGGCGCCAACGCTGGCCCGGATCTCGGGTTCGCAGTGCCGCCCAGCGCCGTTGACGAGCACAGCAAGCTGCTGGGCCAGAATCGCGACTTCCTGGCGCGCCTCatgagcagcgccagcgccagccatGCCagccaccagcaccagcacagCGCGCACAGCCGCGAGGAGGACGAGAACAGCTCCTTCCTGGACGTGGTCGAGTCCAATAACAAtgcggccgccgctgccgccgccgccgccgcggccatGTCCCAATACCACCACAGCGCGGCGGCCAACGGCAGCGCAGCTGGCGCgggcgctgccggcggcggcggcggcgacggtgCTGGTGGGCACACGCCCACCGGCCCACCGACAGCGCCCAGCAGCGTGGAGCCGCCCCAGATGCAAATGAACTCGCTCAGCCACTCGCAGTCGTTCATGAGCTCGTTCTACAACAACGCCAACGCAAGACTgagcggcgccggcgccgtcgttggcgttggcgcCAACTCCTCCTCGGCCAGCATGCTGGTGGAGGCGGCCCTCAACTCCGTTGGCAATATGATTGACAGCGAGAGCAGCGATCTAAAGGTACCCACCGAGAACCACATAAATAGCGACAGTCCGATGAGTGCGCACGTGGATGCGGAGGCGCAGCGCTTTGGCAGCGGCGGGGGGAGCGGAGCGAACGGCCCGGGCATTGGCGCCACGATGGACAACCTGGAGAACGAGCTGAAGATGATGAAGAACCTGGGCAGCTTCCCCATGCAGATACCGCCATTGCCTATGTTCCAGGGCGCTTGCAACATATCGCCGAGCGCCTCGACGCCCACCAATCCGCAGAGTaaccagaaccagaacgaTGTCGATGTGGATGCGGGCAGCACGCCACGGCCTCAGCATCCGGACTCCGATGGCTTCTCCTCGTCGCACCATCGTACGCCGCCCTCGCCGCCGCCCATCTCGCCGGGCCGCGACTACGGCGGCATGTTTGGCGCCGGCAACGGTGCCGGCGGCCCCGGCTCGAATAGCACGCCAGCGGGCAGCTCCAGCGGCCCCCCAACAGGCGGCAACAATCTGTCCGCATCGTCaccgctgccggcgctgcagccgcagcgacGCAACGCCTCCAGCGTGGGCAGCACATATCCCGAGCACGAGCTCATCTCGCCGGCCTCCTCGCCGAGCATACCGCGCTACAATTTCAACGGCGACATGATGCGCCACAAGCGCGCCGtccaggagcaggagcagcaggagcgaCGCCACAACATCTCGCGCCACAACCAAATGTCCAGCGACGAGGAGAACAGCATTATGCCCCAGAACAGCGCCGGCCAGGATATGCGCATGAAGTTCCCGCAATCGCAGATCGATCTCATGTACTCCAAGTACGAGAGCATGGCCAGCAATCTGAAGTACAACAGCCAGGATCTGGACTCGCCGGCCGAGTACAggcagagcagcaacagcaacgcggccagcgcagcggctgccgccgcggcggcggccagtGCCGCCAACGATATGTCCGACCTGCAGGGCCTGGACATGAGCTCGCGCTCGAACGCGTCGAGCAACTATCATCACAACTTCCAGCTGCCGAGCAGCCGCTACCATCACCACATCTACGACATACTGTCCGACCGGGAGCAGAGCcagcaggcgcaggcgcagcagcaggggCCGCCGTCGGTGGTGCACCAGCAGGAGCATGGCAGCCATGGCGGGCACAGCAGCCAGCTGGCGATGCAGCAGCACCAGTCGGCGGCGATGCACAACATGCTCAGCGAGCAGCTGGGCGAGCAGGAGCACGATCAGACCACGTCGGTCGATTTGAGCCGCACCGCCAACTATGTGGTGTCgtcgccgccgcagctgccgtACAATCATCCGCATCACGATATGCTGCGGATGGCATCGCTGGATCTGACGCCAAATACGGCCAACATGACGGTGGGCAACAATCGGTCGTTCCTCTCCTCGCAGATGCAGCACCAGAGCCGCGAGAGTCTCGAGCACCATCGGCTGCTGTCGACGGTGGAGCAGCATCGGATACTGGCCGCCTCGAATGCGGCGGCCGATCAGCATCGCCTCCTCGTCGATCCCACCGCCCACCTGCTGATGGAGCAGAACAATCGCCTGCTGGGCACCGCGGATCAGACGCGTCTCCTCGGCGaatcggcggcggcggccgcccaGAATCGTCACATGGCCCGCAGCTTCGGTGCCTACCATCAGGTGGCCTCCAGCAACTATCATCCGGGCGTGCGGCCGCCACCGGTGCTGCCGTCGGCCAATCATCATGCTTCCAATCCGTCGAATTATCATCCATTTCCCGCCTACTACTAG
Protein Sequence: MKRPTDVRTQCQMQSLPPPSPAHTPTKGFDGNFKLEPNLSVKDFAPPPENGNGNGNGSLESSGVTASMATPTPPQRKRYKKRVQFTTDALNGFAGAKGKGGAAMAAVGAAGASASAAAGYANNSNSFASTPKSKKQEAKAAAAALKAGAAAAAAAAAAAAASSALPEVLDCRIAEKIKSELEASSKESLPSALCLKKAAAAAAAAAAAARHSDEDEDDEEDHQHHQHHHRHHHHQQQQQQQQQQQLSLSTSAAGNVHSSAATAALAASDAVDASSASNGQLGGFHVRSKGQASSKKSQSAKAAAAAAAAAAAAAAAAAAAMMPPNSYDEPEDDSAAGPGDDDDEDDEELDEEALAREMKMEQNFVEEEDEHDIAFRSQQSCRECSISHDHKLCPLRNACGNVTDAVDLAEWIERRNLEALAKLKADAQRQAKVGRPRHDDDEDDMEDMDMDESSQLSELETKPLITFAEASVPAEFELHNVEPNVTGVFARTEVRAYTKLGPLIGQPVQTGEVREGSDMKWIFEMCEAGADKSYLLCCDNPNASNWLRFIRPAPSYEDRNVNLVSIDRQAYFVSCRDLRNGMELLYWSDDCNTMWRKKHTEKTNCGGCNLKFEHPLYYRTHCSVFHDPSMSLTIRKYHCKVCGEAVLGKDNIMKHAAEKHDGKGAYQCQFCNKFFLRLNYLEMHRTYGCASNPNRSRPVCDFCGRKFCQPQKLKAHIKRVHSDMAEVLRDFQCKLCSKLLGSRAALQRHSKEVHSRNSTVVSCPRCQKLFQNRSNLKIHMLTHSGVRPFKCAEPECNAAFTTKQCLQFHYKKVHNYTQEQMPKIERSVAYTFDAYSGGMKVDFLEQAPRRRRKSLEDQNQNSMLSSSMQSDTEYSDDNIFEAIKKSGKSIKDLCRNEPNLSLLSSKISSIFGDKVPAVQQAPIPPNAGGSSVAAGAGRKRKRKKEPATSLAAQQQQQQQQQQQQQQQQQQQQQQQQLQQQQQQQQQQQQQQHAQQCHQQQQQQLHGHLEQSPSHLSHAHQQQQQPQYHSHAHSHGHAHAHPQQQQQQQQQQQQQQQQLQQQQTAALHQQQLHDADEEEESARLEQVRRKQNAQLSLVESFLTTTAQRLSAQQQVQQVVAAAAAVSAMAGAGEDPAKLGHMMGHMGGVGVGVGLDDDDDDDEDDDDGTAHHHHHQQQQQQQQQQQQHQQQHQQQQQHHHSHQSHPHHAHAHSHPHPHPHPHPHQHGQQAAQQPHSEAGYRHAAAMNAALGQNLVVSKGSKKWIGADDRHLSDGGDVANDAAVGGGGGGGSGSGGGGGAGCGQLAGGANAGPDLGFAVPPSAVDEHSKLLGQNRDFLARLMSSASASHASHQHQHSAHSREEDENSSFLDVVESNNNAAAAAAAAAAAMSQYHHSAAANGSAAGAGAAGGGGGDGAGGHTPTGPPTAPSSVEPPQMQMNSLSHSQSFMSSFYNNANARLSGAGAVVGVGANSSSASMLVEAALNSVGNMIDSESSDLKVPTENHINSDSPMSAHVDAEAQRFGSGGGSGANGPGIGATMDNLENELKMMKNLGSFPMQIPPLPMFQGACNISPSASTPTNPQSNQNQNDVDVDAGSTPRPQHPDSDGFSSSHHRTPPSPPPISPGRDYGGMFGAGNGAGGPGSNSTPAGSSSGPPTGGNNLSASSPLPALQPQRRNASSVGSTYPEHELISPASSPSIPRYNFNGDMMRHKRAVQEQEQQERRHNISRHNQMSSDEENSIMPQNSAGQDMRMKFPQSQIDLMYSKYESMASNLKYNSQDLDSPAEYRQSSNSNAASAAAAAAAAASAANDMSDLQGLDMSSRSNASSNYHHNFQLPSSRYHHHIYDILSDREQSQQAQAQQQGPPSVVHQQEHGSHGGHSSQLAMQQHQSAAMHNMLSEQLGEQEHDQTTSVDLSRTANYVVSSPPQLPYNHPHHDMLRMASLDLTPNTANMTVGNNRSFLSSQMQHQSRESLEHHRLLSTVEQHRILAASNAAADQHRLLVDPTAHLLMEQNNRLLGTADQTRLLGESAAAAAQNRHMARSFGAYHQVASSNYHPGVRPPPVLPSANHHASNPSNYHPFPAYY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00803235;
90% Identity: iTF_00491147;
80% Identity: -