Basic Information

Insect: Drosophila sordidula
Gene Symbol: zfh2
Assembly: GCA_035047465.1
Location: JAWNPQ010000320.1:1147752-1171873[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 13 0.56 36 5.0 0.4 3 23 2 23 1 23 0.96

2 13 0.00014 0.0091 16.3 1.4 2 23 217 239 216 239 0.96

3 13 3.5e-05 0.0023 18.2 0.7 1 23 271 295 271 295 0.92

4 13 0.0061 0.4 11.2 0.4 1 22 385 406 385 409 0.91

5 13 9.8 6.3e+02 1.1 0.4 1 21 568 589 568 590 0.86

6 13 1.4 89 3.8 1.9 1 23 611 635 611 635 0.91

7 13 5.8 3.7e+02 1.8 0.4 2 21 747 766 746 770 0.89

8 13 0.27 17 6.0 0.5 1 23 881 904 881 904 0.96

9 13 0.043 2.8 8.5 0.5 2 21 1111 1130 1110 1134 0.89

10 13 2.9e-05 0.0019 18.5 1.4 1 23 1165 1187 1165 1187 0.98

11 13 0.00072 0.046 14.1 1.0 2 23 1194 1216 1193 1216 0.94

12 13 0.00034 0.022 15.1 1.7 1 23 1752 1774 1752 1774 0.97

13 13 0.0016 0.1 13.0 0.4 1 23 1889 1911 1889 1911 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	13	0.56	36	5.0	0.4	3	23	2	23	1	23	0.96
2	13	0.00014	0.0091	16.3	1.4	2	23	217	239	216	239	0.96
3	13	3.5e-05	0.0023	18.2	0.7	1	23	271	295	271	295	0.92
4	13	0.0061	0.4	11.2	0.4	1	22	385	406	385	409	0.91
5	13	9.8	6.3e+02	1.1	0.4	1	21	568	589	568	590	0.86
6	13	1.4	89	3.8	1.9	1	23	611	635	611	635	0.91
7	13	5.8	3.7e+02	1.8	0.4	2	21	747	766	746	770	0.89
8	13	0.27	17	6.0	0.5	1	23	881	904	881	904	0.96
9	13	0.043	2.8	8.5	0.5	2	21	1111	1130	1110	1134	0.89
10	13	2.9e-05	0.0019	18.5	1.4	1	23	1165	1187	1165	1187	0.98
11	13	0.00072	0.046	14.1	1.0	2	23	1194	1216	1193	1216	0.94
12	13	0.00034	0.022	15.1	1.7	1	23	1752	1774	1752	1774	0.97
13	13	0.0016	0.1	13.0	0.4	1	23	1889	1911	1889	1911	0.97

Sequence Information

Coding Sequence: ATGTGCTTCATATGCAAACTGTCCTTTGGCACTGTCAACTCCTTTAGCTTGCATGCGAACACGGATCATAGGCTGAATCTCCAGGAGCTGGAACAGCAGCTTTTAAATCGCGAGTATTCTAGTGCTATCATTCAGCGTAATATGGATGAAAAGCCGCAGATATCGTTTCTCCAGCCGCTTGATGTCAATGCTGTTGAGCCGGTGGATTTGGCTGCCATCGATACCAACCAGGAAATTGCCACCCTCACCCAATTAGCTGCCGATAATTCCAGCATCGATGGTCAGCGGGACGAGCGAGAAGATATTGATGGCGATGGAGTTGGTGCTGAGCTGGGCGAAATGATAGCACCTGGTGATAGTGCCCCAGCTCCGTCATCTCAAAAATCGCACTGCCAGTCCCAATCTCTGCCGCAGCCTCAACGCTCGCCTaatggcagcagcggcggcttgTCAACATCCATGCCCATCTCGCCTAGTGCGTCGTCGGTTGGAAATGCAACTGCATCAAGTTTTACAATTGGTGCCTGCTCCGACCACATCAATGGTCGACCTCAAGGCGTAGATTGCGCTCGATGTGAAATGTTGTTAAACTCGGCACGTCTTAACAGCGGTGTCCAGATGTCCACACGTAACTCATGTAAAACCCTCAAATGTCCTCAGTGCAATTGGCATTACAAATACCAGGAGACTTTAGAAATCCATATGCGTGAGAAACATCCCGATGGAGAGAGCGCCTGTGGATATTGTTTGGCAGGCCAACAGCATCCACGACTGGCACGTGGGGAGTCATACTCGTGCGGGTACAAACCATACCGCTGCGAGATTTGCAACTATTCGACGACCACAAAAGGCAACCTCTCCATACACATGCAGTCGGACAAGCACTTGAATAATATGCAGGAGCTCAACAGCTCACAGAATATGGTCGCTgttgcggcggcagcagcgagcgCGAAATTGCTGCTACCCAGCCCATCACCACAAGGATCGGGCCCCGGTCCGGCGGTGAGTGTGGGAGTGAGCTCGGCAACACAGCAAACAGCGTTAAGTTCATCCAGTGCAAGTGGTAGCGTACTGAGCAGTGCCAGCAACGCTGCCAGTGGTGCAATGGGAACGACGGTGTCTACGGCATCCATCAAGCCCAAGCCGTCGTTTCGTTGCGACATCTGCAGCTACGAGACATCTGTAGCCCGCAATCTACGTATTCATATGACCAGTGAAAAGCATACACACAATATGGCCGTGCTCCAGAACAATATAAAGCACATACAGGCATTCAActttttgcagcagcagcatcaccaACAAGGATCTGCACCCGGAACAGTTGGAGCAAATGCCAACAGTTTCCTGCCCGTACCAGAGGTGGCCCTGGCCGATCTAGCCTATAACCAGGCACTTATGATCCAGCTGTTGCAACAAAATGCTCAAGCAACTgccaaccagcagcagcagctgcatccgCAGACCTCGAATAGCAAATTATCGCCAACGTCGAACTCGCCAGTGAGCACGCCCGACCAATTGCATGGATCGTTCTCATTCTCACCGAAGCCTCTGAAAATGCCACAAGGAATGAACATGGGCATGGGAATGGGCATGGGGGTGGGCATGGCTCCTGCGAGTGATGCTGGGACATCGGCAGGGGAGACGTTGGATGCTTATCCTGATAGTTTGCCGGAATTGTGGCCAACGGCACTTTACAGCTGTCTGATATGCGACTGCTTTAGCACAAATGATATGGACGAGCTCAATCAGCATTTACTGATGGATCGTTCCCGGCAATCCTCAAGCGCTTCGACGGACATTATGGTCATACACAACAATAACTATATTTGCCGACTATGCAACTACAAGACGAATCTAAAGGCAAACTTTCAACTCCATAGCAAGACGGACAAGCACTTGCAGAAGCTCAACTTTATCAATCACATCCGCGAGGGCGGCTCCCGTAACGAGTACAAGCTGCAGTATCAGCCACAACTGGCCACCAATGTGGTGCAGCTCAAGTGCAATTGCTGTGACTTTCACACGAACTCAATCCAGAAGCTGTCGCTGCACACGCAGCAAATGCGACACGATACAATGCGTATGATCTTTcaacatttgcttttaataataCAGAAGAGCCGTATGCGTCAAATATACAGTTCAGGTTCCAGTCACATTCATTCTGAGCGGGAGTCGCCTATGCATGATGATCAGGAGCAGCATCAGCCGTCTATGAAAAAGGCCCTTTACTGCCAGCTGTGCGATTTTGTCGCCAAAAATCTGCACGAGATGGTGCAACATGTGAAGGGCTTAAGGCACATGCAAGTTGAACAGATTGTTTGCTTGCAACGCCGCAGCGAAAACATTGAAATGCTTGGACTTAATGAGGTATTTAAGGTCACTGAACAACCGCCAGCTAGCACTGAAGattCAAACCTTGATTTTGGCCTCAACCTGGCAACGGCAGCTTGCGTAGGAGCATCCACAGATACTGGATTTGGTGTGGCGAGTGCATCATCAACAGACGCCAACATATTTTCGCCTGCTTCTgtctccagctgctcgaccTCATGCGGCAAGGCTCAACCACGAAATGTATCCCCATTGCCGACTGCTGGTGACCTCCATCTAAATGCTTCAACCACGGTTTTCAAATGCAATCTCTGTGAATATTTTGTACAATCTAAAAAAGACATAGAAAGTCACATTGAGTCTCTCCACCCAACTGCGGAAGGCGATGACTTTACCAGCATACCCACAAACGCAGCAGCTCTGCAAGCTTTTCAGACAGCCGTCGCAGCCGCCGCTCTTGCCGCCGTCCAGCGCTGTAATGCCAGTACCAACCCCACGTCCACCGCCGTAGAAGCAGACGCAGATGCGCGTAGTGGCGACGCCGATTGTCCCATCGATATTAAGCGGGAACGGCTGGAGGAGAGCGATGAAACTATCACTAATAGTGCTGACTTAAAGGACAATCCAATAGTAGAGAGCAACCGCAATAAGAGTAGAGTTTTGCCAAAGAATGAGTCTACGCCCCAGTCGGGTGTATCGTGTCCCCTATGTCTAGAAAGCGGATATAGTGAGAAATCTCTATTGGAAACTCATCTTATGGGCGTGCACAGCGTAACTCGAGATGGTCTTGCCagactgctgcagctggtaGACCACAAGGCCTGGCGATCTGCAAATACAACCGATTCGACAGCAACTTCAGTGTCATCAGTGCCCTCTGAAAGAATACTTGATGAGATTAAATGTAATGTCAACGCCGAAGAGTATATATCCTCGCCCACATCCGCACCAACGGCCTGTTCTAACGCTGGCACTATGCAGGGCATCTCGTGCCAGCAGTGTGACGCAAACTTCAAGCACGAGGAGCAGTTGCTTCAGCATGCCCAACAGGCGCAACACTTTCCAACGCAAAACAGCGAATACCTCTGCCTAGCTGTTACTCATGACTCGCACATGAGCCTAGTAATTTCGGAGCGGCATGTCTATAAGTACCGCTGTAAACAGTGCTCTCTGGCGTTTAAGACACAGGAAAAGCTAACCGCCCACATGCTTTACCACAGCATGCGGGACGCTACCAAATGTTCCCTTTGCCAGCGAAACTTTCGTAGCACTCAGGCTTTACAGAAGCATATGGAGCTGGCTCATGCAGCCGAGTGTACCGCTGTTACGACTAGCAGTCCTCGGGACCTATCACCTGGTTTCAGTGCTAGCGAAATTGAGAAGATACCAGCTGAGCCAAGTGTTTTTGACTTTAGTACAACGCGGACTAGTGAATCTGTTGCCAAAACGAACGAAGCTGTAAAAGAATCCCCCCAGCGTTCTCGATCGCCCTTTCAACTAGATTCACAATCGAAGGAGCCGCATCAACGCTCAGCATTGTTATCGCCAAATGCTCTTGAGGACCCTCCAActgagcagcaacagcacttTGCTGTACTAACTGCAGCTTTgcttaagcagcagcaggaagcaGTTGGTCAGACAGTAGATACACAATTGCCCATGTCGCCGGGCGGGATGCAGCAGCTTCAGGTGAAGGCACAACAGCAGAGTCCTTTCGGCAGCAGTATGAATCAACAATCATTTCACGGCCTTCAAAGCATACAGAATTTGCAGCAAATTCAACAACAGTTGAGCGCCGCAGCGGCCGCATCGGGAATGCCCATCAATCCGGTGGACATGCTCAATCTCATGCAATTCCATCATTTGATGTCGCTCAATTTCATGAATCTAGCACCTCCCCTAATTTTTGGAGCCAATGCTTCCGGCGGTAATTCCGCAACAGCAGGAGGCGTCCAGAACAATGGCATTATCCCAACCCCTACGACTAACAGCTCCGAGCACCAACAAAAATGCTCTGCCAGTGCAGCCTCTTTAACAGGTGATGCCGCCAACATGAATCTCATCACGCAGTCAAGTATGACTAACAATAATCAGCAACAGTTAAGTAGCAACCAGAAACGCGCACGCACCCGTATCACCGACGATCAGTTGAAGATTCTGCGCGCCCATTTTGATATAAACAACTCACCTAGCGAAGAGAGCATTATGGAAATGTCGCAGAAAGCAAATCTTCCAATGAAGGTCGTAAAGCATTGGTTCCGCAACACGTTGTTCAAGGAACGACAACGCAACAAGGACTCGCCATACAACTTTAATAATCCGCCGTCAACAACACTGAATCTGGAGGAGTACGAGCGTACTGGTCAAACCAAGCAGCACTATcaaaatcagcatcaacaacatctgcagcagcaacaacaacaacaaaccaatTGCTTCGAGACCAAGTCAGAAAGCGGCAGTTCAGATGTGCTTTCGCGCCCACCGACCCCAAATAGCGTTGCAGCCAGCAATCTCTATAGCAGCATGAACGATTTACTGAGTCAACAGCTGGAGAACATCGGCAGTAATATGGGTCCAcctaaaaaattgcaaatatcaGCATGCGCGCAATTAGAGAGCAACTCTTCGAACTCATCGAACTCGTCCTCGTCGACATCCGGTGGAAAGCGTGCGAATCGGACACGTTTCACAGACTATCAAATCAAAGTTTTGCAGGAATTCTTCGAGAACAATTCGTATCCCAAGGACAGTGATCTTGAATATTTGAGCAAGCTTCTGCTCCTGTCGCCACGGGTAATTGTTGTATGGTTCCAAAATGCACGGcaaaagcagcgcaaaatCTACGAAAATCAGCCGAACAATACGCTGTACGAAAGTGAGGAGACCAAAAAGCAGAACATTAACTACGCATGTAAAAAATGCAGCTTAGTTTTCCAGCGCTACTATGAGCTAATACGCCATCAAAAAAACCACTGCTTTAAGGAAGAGAATAACAAGAAGTCAGCAAAAGCACAAATAGCTGCCGCGCAAATAGCTCACAATCTAAGCTCGGAAGATTCAAATTCTTCCATGGATATTCACCATGCCGCTGGGCCAACCGGTTTGGGTTTGGCACCACAAAACGTGGCAGCTGccgtggctgttgctgctgctgctgcagcagctcattCTGGATCTCAGCAATACGGCTCGTCGCCCTCGCCACAGCATTTATTTAGCAAGTCTTCATCGCTCACGGATTTCAGTCCATcgacaacgccaacgccacCTCAGCGGGAGCGCAGCAATAGTCTGGATCAGCAGCGAATGCCAAAGTTTGACTGTGACAAATGCGAGATGCAGTTTAATCAATTGGAACTACTGCGTGAGCATCAATTAATGCACTTAATGAGCCCGGCACTCTTTCCGAGCAGCCATCAGTCAAATCAGGCCGAGGCGGCCTATGGACCCTTTGGCACCATATTGCAAGGCCTGCAGCAGGCagcccaacagcaacaacagcatcagccaCAGCCGCCTCCGgctaaaaaaaggaaatgctCCGAGAGCTCATCGAACGCAGAGGAGGCAACTATGGGAGAATTTGAGactttacataaaaaatacgAGTTCCTATACCAATACTTCATGCGACATGAAACTAATGCAGAACTTAAACAGCAGTTCCtaatgcaacaacagcagcagcaacagcatggACAAGAGTCAGACTTGGAATTGGAGTTCTTAAGCAATTTTTATCAGCAGAGTGAGCTGAAAAAGATCAGCAGCTATGATTTTTTACTGCAATATTATCGCAAAAATGAAGATTCTTTAAAGCACGAACATTCGTCATTTAGCTCCAGCAAGAAGCCAACTATTGAGTTTCTGCTACAATATTATCAGCTTAACGAGTCGAAAAAGTTTTTTCAGTTAGCTGCCTCGCCCCAAACAACACCTGATGGCACAGAATCACAGCCGTCGTCGCATCAGCCGAACGCGACGACGGatgaaacaattaaattgatcGGCAGACAGGAACAATCACAAGAGCAAGAGCGCGAAGTAAAAATGGATCTGGACTTAGACTACTCTACTGAGTCCAACGACATTGGTGATGATGTGCATGAGAAACTGAATAACAACCACATCAACATTGATATTAGCCTAACCGAAGGGCAGAATTTTGATCATCAGAAAGTAAATCTTAAAAAACGAGTCGTACAAGTTTGGTTTCAGAACTCCCGGGCAAAAGATAAGAAATCAAGGAATCAGCGCCAATATGCACACATTTCGGACGATAATAACAGTTTTGACGGATCTAGCGGTAAAgaagccagcaacagcaacagcaatggcaTTAAGAGCAAGTCCCTGCCATTGTGCCAAGAGCCAATAGTTGCTTCTAGCACACTCATGGAAGTCGATTCCGATCTGCAGCTGCAAGACTGTCAATTATGCCAGATCCCCCAGGTGAATATGAATAAGCACGCATTCAGTGTTGAGCACATCTGCAAGATGAAGGAACTTCTCGAGCAAACCAGCGAGCTCTATGCCCCCAGTAATGCCAGTGGAAGTGATGACAACGATTCTGACAGGGAGCGGCGCTTTTACAGCCTTTCCAAGGCATTCCTCCTGCAGCATGTTGTGTCCAATACTAGCAGCATTTTACCGACTAGCACTGAGCGTCTCACAGACAGTGGGAACTGCGGTGGGCTGGTGAACTTTGACCCGACAGCGTCTActactgcgactgcgactgcaactgcaacattgACTGCTACGGCGAATGACTCTAAGAACGGACCTGAAGCGGCCCATCGCCATTTGGCTGGCGACATTGCCGTCTCTGTTAACGATGACAACGAAATCCCTGAACCTGGCTCCAGACAGAATCAATCAGGCAATCGGGACATCATTCAACAACTATTCAATCGCAATCACATCACTGtTATAGGTGGCAAATAA
Protein Sequence: MCFICKLSFGTVNSFSLHANTDHRLNLQELEQQLLNREYSSAIIQRNMDEKPQISFLQPLDVNAVEPVDLAAIDTNQEIATLTQLAADNSSIDGQRDEREDIDGDGVGAELGEMIAPGDSAPAPSSQKSHCQSQSLPQPQRSPNGSSGGLSTSMPISPSASSVGNATASSFTIGACSDHINGRPQGVDCARCEMLLNSARLNSGVQMSTRNSCKTLKCPQCNWHYKYQETLEIHMREKHPDGESACGYCLAGQQHPRLARGESYSCGYKPYRCEICNYSTTTKGNLSIHMQSDKHLNNMQELNSSQNMVAVAAAAASAKLLLPSPSPQGSGPGPAVSVGVSSATQQTALSSSSASGSVLSSASNAASGAMGTTVSTASIKPKPSFRCDICSYETSVARNLRIHMTSEKHTHNMAVLQNNIKHIQAFNFLQQQHHQQGSAPGTVGANANSFLPVPEVALADLAYNQALMIQLLQQNAQATANQQQQLHPQTSNSKLSPTSNSPVSTPDQLHGSFSFSPKPLKMPQGMNMGMGMGMGVGMAPASDAGTSAGETLDAYPDSLPELWPTALYSCLICDCFSTNDMDELNQHLLMDRSRQSSSASTDIMVIHNNNYICRLCNYKTNLKANFQLHSKTDKHLQKLNFINHIREGGSRNEYKLQYQPQLATNVVQLKCNCCDFHTNSIQKLSLHTQQMRHDTMRMIFQHLLLIIQKSRMRQIYSSGSSHIHSERESPMHDDQEQHQPSMKKALYCQLCDFVAKNLHEMVQHVKGLRHMQVEQIVCLQRRSENIEMLGLNEVFKVTEQPPASTEDSNLDFGLNLATAACVGASTDTGFGVASASSTDANIFSPASVSSCSTSCGKAQPRNVSPLPTAGDLHLNASTTVFKCNLCEYFVQSKKDIESHIESLHPTAEGDDFTSIPTNAAALQAFQTAVAAAALAAVQRCNASTNPTSTAVEADADARSGDADCPIDIKRERLEESDETITNSADLKDNPIVESNRNKSRVLPKNESTPQSGVSCPLCLESGYSEKSLLETHLMGVHSVTRDGLARLLQLVDHKAWRSANTTDSTATSVSSVPSERILDEIKCNVNAEEYISSPTSAPTACSNAGTMQGISCQQCDANFKHEEQLLQHAQQAQHFPTQNSEYLCLAVTHDSHMSLVISERHVYKYRCKQCSLAFKTQEKLTAHMLYHSMRDATKCSLCQRNFRSTQALQKHMELAHAAECTAVTTSSPRDLSPGFSASEIEKIPAEPSVFDFSTTRTSESVAKTNEAVKESPQRSRSPFQLDSQSKEPHQRSALLSPNALEDPPTEQQQHFAVLTAALLKQQQEAVGQTVDTQLPMSPGGMQQLQVKAQQQSPFGSSMNQQSFHGLQSIQNLQQIQQQLSAAAAASGMPINPVDMLNLMQFHHLMSLNFMNLAPPLIFGANASGGNSATAGGVQNNGIIPTPTTNSSEHQQKCSASAASLTGDAANMNLITQSSMTNNNQQQLSSNQKRARTRITDDQLKILRAHFDINNSPSEESIMEMSQKANLPMKVVKHWFRNTLFKERQRNKDSPYNFNNPPSTTLNLEEYERTGQTKQHYQNQHQQHLQQQQQQQTNCFETKSESGSSDVLSRPPTPNSVAASNLYSSMNDLLSQQLENIGSNMGPPKKLQISACAQLESNSSNSSNSSSSTSGGKRANRTRFTDYQIKVLQEFFENNSYPKDSDLEYLSKLLLLSPRVIVVWFQNARQKQRKIYENQPNNTLYESEETKKQNINYACKKCSLVFQRYYELIRHQKNHCFKEENNKKSAKAQIAAAQIAHNLSSEDSNSSMDIHHAAGPTGLGLAPQNVAAAVAVAAAAAAAHSGSQQYGSSPSPQHLFSKSSSLTDFSPSTTPTPPQRERSNSLDQQRMPKFDCDKCEMQFNQLELLREHQLMHLMSPALFPSSHQSNQAEAAYGPFGTILQGLQQAAQQQQQHQPQPPPAKKRKCSESSSNAEEATMGEFETLHKKYEFLYQYFMRHETNAELKQQFLMQQQQQQQHGQESDLELEFLSNFYQQSELKKISSYDFLLQYYRKNEDSLKHEHSSFSSSKKPTIEFLLQYYQLNESKKFFQLAASPQTTPDGTESQPSSHQPNATTDETIKLIGRQEQSQEQEREVKMDLDLDYSTESNDIGDDVHEKLNNNHINIDISLTEGQNFDHQKVNLKKRVVQVWFQNSRAKDKKSRNQRQYAHISDDNNSFDGSSGKEASNSNSNGIKSKSLPLCQEPIVASSTLMEVDSDLQLQDCQLCQIPQVNMNKHAFSVEHICKMKELLEQTSELYAPSNASGSDDNDSDRERRFYSLSKAFLLQHVVSNTSSILPTSTERLTDSGNCGGLVNFDPTASTTATATATATLTATANDSKNGPEAAHRHLAGDIAVSVNDDNEIPEPGSRQNQSGNRDIIQQLFNRNHITVIGGK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00597970;
90% Identity: iTF_00597970;
80% Identity: iTF_00597970;